Research on weight loss and its health effects. Covers GLP-1 injections, companion digital programs, pregnancy guidelines, and asthma benefits.
Researchers found that using analytical language when describing weight loss goals led to greater weight loss success and lower dropout rates. Analytical language, such as focusing on what's important and why, was associated with more weight loss and less program attrition.
A long-term study found that bariatric surgery improves physical activity and diet quality in participants, but only a small percentage meet federal guidelines. Patients may need continued support to maintain weight loss and health benefits after surgery.
Research found that food insecure teens are more likely to attempt weight loss, while college students who drink may compensate with unhealthy eating behaviors. Additionally, studies linked sugar-sweetened beverage consumption to higher triglyceride levels in youth and identified potential mechanisms behind this association.
Scientists at CNIC discovered a complex network between liver tissue connections that allows the liver to regulate body temperature. The secretion of IL-12 by liver-infiltrating macrophages blocks FGF21 production, reducing heat generation by brown fat in mice.
A new study by the Physicians Committee for Responsible Medicine found that a vegan diet rich in legumes is associated with decreased weight and improved insulin sensitivity. The 16-week study involved 244 overweight adults who followed either a low-fat vegan diet or made no changes, resulting in an average weight loss of 13 pounds.
Researchers found that weight-loss surgery patients saw significant reductions in several types of cancer incidence and improved survival rates compared to non-surgical patients. The 10-year incidence of any new cancer was lower and the 10-year survival rate was higher for bariatric group patients.
A recent study reveals that patients with lower body mass indexes (BMIs) could benefit from weight-loss surgery due to its effectiveness in treating type 2 diabetes and other comorbidities. The study found that patients with Class I obesity who underwent weight-loss procedures had shorter hospital stays, fewer complications, and improv...
A customized WeightWatchers program has been shown to effectively manage Type 2 diabetes by lowering blood glucose levels and promoting significant weight loss. Participants in the six-month clinical trial experienced improved glycemic control and overall well-being, with clinically meaningful and statistically significant results.
A recent study published at the Euroanaesthesia Congress found that patients with higher body mass index (BMI) and weight prior to bariatric surgery are more likely to experience complications and have worse outcomes. The research analyzed data from over 4,000 adults who underwent weight loss surgery between 2006 and 2020, revealing a ...
The US healthcare system faces a significant challenge in providing high-quality, personalized obesity care due to lack of insurance coverage for effective medications and societal stigma. Recent efforts aim to address this issue through framework development and policy changes, which may lead to improved patient outcomes and cost savi...
A new mobile app provides effective support for children with obesity by tracking their weight development in real-time and offering personalized care. The app achieved twice the weight loss results compared to conventional care, particularly benefiting adolescents who were previously difficult to reach with behavioral therapy.
A study published in Human Reproduction found that men with obesity who lost weight saw a 50% increase in sperm concentration and a 40% increase in sperm count over an 8-week period. This improvement was sustained for up to 52 weeks and even doubled for those who maintained weight loss after a year
A new weight-loss intervention has been developed to target the instinctive desire to eat, particularly in individuals who struggle with resisting food cues. The Regulation of Cues program trains individuals to use natural hunger cues, reinforces tolerance of cravings, and inhibits urges to eat palatable foods when not physically hungry.
A recent study published in Obesity Reviews found that resistance training, in conjunction with a reduced calorie diet, can lead to significant fat mass and muscle loss. This breakthrough highlights the importance of considering non-aerobic exercise options for individuals struggling with obesity.
A new study provides recommendations for behavioral weight loss interventions to address the unmet needs of Black people with obesity. The research emphasizes the importance of enhancing recruitment and retention of Black men and women in behavioral weight loss intervention studies, as well as combining policy with behavioral changes.
A recent study found that only 3% of adults with a recording of overweight or obesity in England are referred to weight management programmes, indicating under-reporting in primary care. The programme's effectiveness varies across the country, and the lack of national registry makes it difficult to determine access for patients.
A meta-analysis of 11 randomised trials found that vegan diets for at least 12 weeks can lead to clinically meaningful weight loss and improved blood sugar control. However, vegan diets did not affect blood pressure or triglycerides compared to other diets.
Researchers found that restricting calories and eating at the right time of day can lead to a longer, healthier life. Mice on a reduced-calorie diet lived up to 35% longer when fed at night, extending their median lifespan by nine months.
A randomised trial found that poor sleeping habits may contribute to regaining weight after weight loss in adults with obesity. Exercise sessions per week can help maintain better sleep and aid in weight loss maintenance.
Canadian and German researchers have identified personalized prescriptions that combine drugs to treat obesity and Type 2 diabetes. The combination therapy shows higher effectiveness in some patients and fewer side effects compared to single drugs. Studies are now needed to understand why individuals respond differently to the treatment.
A study published in Obesity found that two specific brain networks, FN1 and FN2, are strongly linked to weight loss success. The neural circuits involved sensory and motor skills (FN1) and self-regulation and attention (FN2).
A new study suggests that a diet high in protein, zinc, and niacin, and low in saturated fat, can improve blood vessel flexibility. The study found improvements in metabolic and cardiovascular health, including reductions in calorie and saturated fat intake, increases in zinc and niacin, and improvements in blood vessel function.
A UK study of over 400,000 adults with obesity found that losing weight reduces the risk of 13 obesity-related complications, with greater benefits for those with lower initial BMIs. Weight gain increases these risks, particularly in individuals with lower starting BMIs.
Researchers will enroll 1,000 adults in a placebo-controlled trial to assess the effects of low-cost phentermine on weight loss and related health metrics over two years. The study aims to provide long-term treatment options for patients struggling with obesity.
An automated nutrition app called eNutri improved participants' healthy diet scores by 6% compared to a control group. The app provides personalized nutrition advice based on evidence and uses a diet scoring system.
A study suggests that intense exercise can help rats resist cues for high-fat food pellets, even after a 30-day diet. The researchers found that exercise modulated the rats' willingness to work for these cues, reflecting their craving level.
A study published in Current Biology found that consuming non-essential amino acids can curb appetite and encourage physical activity in mice. This mechanism is thought to be rooted in evolutionary history, where eating these amino acids promoted the urge to seek out more nutrient-rich food sources.
The 9th World Congress on Targeting Microbiota 2022 will focus on recent advances in the microbiota field and therapeutic strategies. Key findings include research on probiotic strains, natural mineral waters, and extracellular vesicles.
Researchers found that fighters who rapidly cut weight before bouts are more likely to suffer concussions or be misdiagnosed with head trauma. The study also discovered that the practice may not offer a competitive advantage and can leave fighters at a disadvantage more often than not.
A new study published in Surgical Endoscopy found that adolescents with obesity who underwent laparoscopic sleeve gastrectomy benefited from reduced obesity and concomitant organ damage, regardless of their age at the time of surgery. Additionally, adolescents with a family history of bariatric surgery had a higher weight prior to weig...
A study published in the Journal of Cachexia, Sarcopenia and Muscle found that BAM15 improves health outcomes for aged mice with obesity by preventing muscle loss and increasing energy expenditure. The compound helped mice lose fat, gain strength and increase physical activity.
A new study from Northwestern University found that once-weekly prednisone treatment improved exercise endurance, increased lean body mass, and reduced weight in obese mice. The treatment also promoted nutrient uptake into muscles and increased adiponectin levels, a hormone that helps protect against diabetes and insulin resistance.
A new study suggests that dramatic swings in food intake can have long-term impacts on cardiovascular health and metabolism. Researchers found that rats who experienced cycles of weight loss and gain had reduced heart and kidney function, as well as increased insulin resistance.
A large cohort study found that babies born to men who took metformin during sperm development were at increased risk for genital defects in boys. Diabetes control affects sperm quality, so men should discuss alternative treatments with their doctors before conception. The findings suggest a need for further study on treatment of prosp...
The Experimental Biology (EB) 2022 meeting features live presentations and a moderated Q&A session on groundbreaking studies. The virtual press conference reveals potential treatments for Parkinson's disease, COVID-19 vaccine-associated side effects, and alleviating food allergies.
This year's Experimental Biology 2022 meeting features groundbreaking studies on COVID-19 vaccine-associated symptoms in non-menstruating people, a plant compound showing promise for alleviating food allergies, and the potential of omega-3s to boost immunotherapy's cancer-fighting power. Researchers also explore the safety of using CBD...
Intermittent fasting produces mild to moderate weight loss and improves cardiometabolic risk factors, comparable to traditional calorie-restricted diets. The review also dispels myths about intermittent fasting, including the misconception that it leads to weakness and decreased concentration.
A randomized study of 379 women with obesity and unexplained infertility found that intensive lifestyle changes that shed pounds led to no better chances of pregnancy than simply increasing physical activity without weight loss. The study also showed significant health benefits from weight loss, including a decrease in metabolic syndrome.
The green Mediterranean diet induces specific microbial changes in the gut microbiome, enriching with bacteria that positively affect glucose metabolism and insulin sensitivity. This novel diet also promotes genetic pathways involved in reducing branched-chain amino acids linked to insulin resistance.
A new analysis by University of Copenhagen researchers found that a Nordic diet has positive health benefits regardless of weight loss. The diet's unique fat composition, high in omega-3 and omega-6 unsaturated fats, plays a significant role in lowering blood sugar and cholesterol levels.
A new study from the University of South Australia has found that popular weight loss diets can be expensive, with costs ranging from $345 to $625 per week. The most cost-effective diet was modelled on the Australian Guide to Healthy Eating and adapted for weight loss through calorie restriction.
A new study found that an anti-tumor drug, camptothecin, can activate a natural hunger-suppressing pathway in mice, leading to significant weight loss. The mechanism involves the elevation of growth differentiation factor 15 (GDF15), which suppresses food intake and reduces body weight.
A recent commentary argues that treating obesity should prioritize compassionate care and focus on health rather than weight. The researchers aim to eliminate the false dichotomy between eating and weight disorders, promoting a patient-centered approach that screens for and addresses eating disorders throughout treatment.
Exercise interventions delivered in primary care appear to boost moderate to vigorous intensity activity by an average of 14 minutes a week. Participants also weighed 1 kg less than controls at follow-up, highlighting the critical role of primary care professionals in promoting healthy behavior changes.
A study published in Obesity found that telemedicine can mitigate barriers to obesity care, including limited access to specialized care and high costs. Virtual interactions between patients and healthcare providers may be more cost-effective and lead to better weight loss outcomes.
A new study reveals that middle-aged men perceive weight gain as an inevitable consequence of family and career commitments. The research found that these men experience low self-worth and despondency, despite awareness of health risks, due to a lack of education on nutrition and lifestyle factors.
A new study published in JAMA Network Open suggests that gastric bypass surgery is the most effective treatment option for patients with severe obesity and type 2 diabetes, leading to greater weight loss and a higher rate of remission. The study found that gastric bypass produces better results regardless of diabetes severity.
Researchers analyzed the motivations and strategies of over 6,000 long-term weight-loss maintainers, finding that perseverance, consistently tracking food intake, and focusing on health goals were key to success. The study's findings may lead to new approaches in counseling and lifestyle interventions.
A study found that rapid weight gain from antipsychotic medications can contribute to loss of agency, hope, and social withdrawal. Understanding this psychological journey may offer new targets for weight loss treatments.
A new study found that increasing sleep duration by an average of 1.2 hours per night reduced participants' overall caloric intake by an average of 270 kcal per day. This translates to roughly 12 kg, or 26 lbs., of weight loss over three years if the effects were maintained.
A new study finds that weight loss is associated with a 46% reduced risk of developing colorectal adenoma. Adults who are initially overweight or obese may be able to reduce their risk by losing weight, while weight gain increases the chance of developing adenoma.
A recent study published by The Obesity Society found that metabolic adaptation after weight loss increases the time necessary to achieve weight-loss goals in premenopausal women. The study, which included 65 participants, revealed a significant delay in achieving weight-loss goals due to metabolic adaptation.
Scientists at Nanyang Technological University have developed a novel therapeutic approach to tackle obesity, reducing body fat and improving blood markers through a hydrogel injection and near infrared light treatment. The treatment shows significant promise in lab trials, with mice experiencing reduced body mass and improved metabolism.
A 24-week study found that dogs fed a reduced calorie, high-protein, high-fiber diet achieved healthier weight without losing muscle mass. Their serum triglycerides, insulin, and inflammatory markers decreased with weight loss.
A new study published in Cell Reports Medicine found that a cancer drug called ADI-PEG 20 improved insulin sensitivity, cholesterol levels, and reduced inflammation in mice. The treatment also caused significant weight loss in obese mice, suggesting potential benefits for human obesity treatment.
A new interdisciplinary treatment method has shown significant improvements in reducing overeating episodes and emotional issues among individuals with morbid obesity. The treatment combined mental health care with somatics, resulting in a nearly 30% reduction in overeating episodes and improved emotional well-being.
A study of nearly 12,000 obese patients found that substantial weight loss achieved through weight loss surgery was associated with improved outcomes after contracting COVID-19, including lower risk of severe disease. The results suggest that weight loss surgery may help mitigate the severity of COVID-19 in individuals with obesity.
A Cleveland Clinic study found that prior weight loss achieved with bariatric surgery was associated with a 60% lower risk of developing severe COVID-19. Patients who underwent weight-loss surgery had better clinical outcomes, including reduced hospitalization and need for supplemental oxygen.
A new study found that incorporating frequent periods of enjoyable movement into daily life leads to better short-term and long-term weight loss compared to structured exercise. The intervention, which encouraged participants to move more often throughout the day, resulted in similar weight loss and improved maintenance relative to a h...
A new study found that news media amplified rather than rectified misleading health information from TV personality Dr. Oz, resulting in the further spread of misinformation. The researchers called for government oversight to lessen the risk of spreading inaccuracies.