A multidisciplinary taskforce developed a Clinical Care Pathway for NAFLD/NASH, outlining practical guidance from screening to patient care management. The pathway aims to provide efficient, safe, and value-based care for patients with NAFLD and NASH, highlighting the importance of early interventions and shared decision-making.
Problem-solving therapy led to short-term changes in the amygdala, a key region for emotion regulation, in individuals with comorbid depression and obesity. The study suggests that neural target changes at two months predicted improved behavioral outcomes after 12 months.
A new USC study found that artificial sweeteners like sucralose can trick the brain into feeling hungry, leading to increased calorie consumption. This study, one of the largest to-date on artificial sweeteners, suggests that females and people with obesity may be more sensitive to these sweeteners.
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A new study found that people of normal weight with type 2 diabetes can achieve remission by losing weight. Eight out of 12 participants achieved remission after losing 10-15% of their body weight, with levels of fat in the liver and pancreas falling substantially and insulin-producing cells restored. The study supports the idea that e...
A recent US study found that major weight loss can reverse most cardiovascular risks associated with obesity. The study analyzed data from over 20,000 adults and found that the risk of high blood pressure and dyslipidemia was similar in those who lost weight and those who never had obesity.
A new UNSW Sydney-led study suggests that strength training can lead to significant weight loss, with participants losing an average of 1.4% of their total body fat after a five-month program. The study analyzed existing evidence and found that this level of fat loss is comparable to cardio-based exercise.
Increasing physical activity and improving fitness are superior to weight loss in reducing mortality risk and treating obesity-related health conditions. Employing a weight-neutral approach also reduces the risks associated with yo-yo dieting.
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A pilot study at the University of Cincinnati found that young adults with ASD and ID can lose or maintain weight with a system of education and support in place. Participants and parents reported knowledge and behavior change, with two participants losing significant weight.
A new study from Institute for Systems Biology (ISB) reveals that the genetic capacity of the gut microbiome is strongly associated with weight loss success or failure. Microbiomes of those who lost weight had higher bacterial growth rates and were enriched in genes that divert dietary nutrients toward bacterial cell growth. In contras...
Top-performing diet and nutrition apps often track dietary intake, anthropometrics, and physical activity but lack behavior change features. A new study in the Journal of Nutrition Education and Behavior found that premium versions offered more features than free ones, but these did not significantly impact app ratings or user engagement.
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A large-scale review of clinical evidence suggests that losing significant weight through diet or surgery can bring about type 2 diabetes remission. Meal-replacement diets and low-carbohydrate diets were found to be effective in achieving remission, with people who lost the most weight being more likely to succeed.
A new study from NYU Langone Health found that losing weight and managing excess body fat can significantly reduce the risk of lung disease in firefighters exposed to toxic substances on 9/11. The study analyzed 20 years of data from over 5,700 first responders and identified five key factors that predict lung disease.
A recent study published in Current Biology found that individuals with obesity burn fewer calories on body maintenance when exercising, reducing the calorie-burning gains of exercise. This reduction in energy expenditure was most pronounced in individuals with obesity and older adults.
A study published in Current Rheumatology Reviews found that rehabilitation exercises significantly improved functional strength and reduced weight in knee osteoarthritis patients. The researchers also noted an increase in exercise adherence among the rehabilitation group compared to the control group.
A new study by Salk scientists found that time-restricted eating (TRE) confers multiple health benefits, including reduced risk of type 2 diabetes, fatty liver disease, and sepsis, regardless of age and sex. TRE may also protect against infectious diseases like COVID-19 and improve insulin resistance.
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Research suggests that dieting is a consequence of an unhealthy food environment, rather than the cause of weight loss problems. Experts recommend refocusing concerns on changing the food environment to curb dieting and related issues.
Patients who underwent bariatric surgery reported improved physical health, energy, and reduced body pain compared to those on medical therapy alone. Significant weight loss and insulin independence drove these improvements in general health measures and quality of life.
A study by Cleveland Clinic found that combining a weight management program with FDA-approved anti-obesity medications leads to significant weight loss among adults with obesity. The research showed that participants who had access to the medications averaged -7.7% weight loss at 12 months, compared to -4.2% in those without medication.
A University at Buffalo-led study found that SGLT2 inhibitors cause a median weight loss of over 6 pounds in Type 2 diabetes patients, compared to 2.5 pounds with GLP-1 receptor agonists. The findings suggest that SGLT2 inhibitors may be more protective against weight gain caused by other antidiabetic drugs.
Researchers found that extreme caloric restriction diets alter the gut microbiome, leading to weight loss in participants. The study suggests that a decrease in gut bacteria and an increase in Clostridiodes difficile may be responsible for the observed weight loss effects.
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A comprehensive review of 315 clinical trials found that most weight-loss supplements and therapies did not produce significant weight loss. Only 16 studies demonstrated significant results, with weight loss ranging from 0.3 to 4.93 kg.
A new study suggests that alternate-day intermittent fasting may offer no unique health benefits over a standard daily diet. In contrast, traditional daily energy restriction resulted in greater weight and fat loss. The researchers note that longer studies with larger groups are needed to confirm these findings.
A new study published in Science Translational Medicine found that intermittent fasting diets are not the most effective way to lose weight. Participants who followed a traditional diet with reduced calorie intake lost more weight and fat mass compared to those who fasted on alternate days.
A study by Brigham and Women's Hospital found that patient-provider discussions about bariatric surgery result in patients with obesity losing more weight; however, such discussions occur in less than 10% of eligible cases. Patients who had these conversations were 10 times more likely to undergo weight loss surgery.
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A new study suggests that using a brain-training app can help people reduce their junk food consumption and lose weight. The app trains users to associate healthy foods with stopping and unhealthy snacks with avoiding, resulting in an average weight loss of half a kilogram and a small increase in healthy food eaten.
A recent study by the University of Washington found that living in a more densely populated neighborhood is associated with lower body weight and less obesity. However, proximity to fast-food restaurants or supermarkets did not have a significant impact on weight gain.
A study conducted in Brazil found that a cognitive-behavioral approach to treatment can significantly yield weight loss and improve quality of life. The program was shown to be effective in increasing quality of life in all domains, physical, psychological, social, and environmental, while reducing symptoms of depression.
A double-blind study found that combining endoscopic sleeve gastroplasty (ESG) with semaglutide increased weight loss in patients, with the ESG group losing an average of 26.7% of their total body weight compared to 19.6% for the control group.
A new study found that semaglutide causes similar weight loss in patients aged under 40, 40-60 years, and 60 years and over. The treatment also showed a more pronounced effect on body composition in younger patients.
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A new study has found a reduced risk of eye cataracts associated with obesity surgery. Patients who underwent weight loss through bariatric surgery showed a lower incidence of cataract compared to those who did not have surgery, especially when performed before age 60.
Researchers found that semaglutide treatment leads to significant weight loss across various patient groups, including those with different ages, sexes, and body weights. Female participants and those with lower starting body weights achieved the most substantial weight losses.
A virtual weight-management support group during lockdown resulted in clinically meaningful weight loss for 27% of participants, associated with reduced risk of diabetes and other chronic conditions. Average weight loss was 7.4lbs or 3.5% of body weight.
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The COVID-19 pandemic's restrictions both spurred motivation and supported participation in an online weight management program, yet had a negative impact on mood and behaviors. Participants attributed lockdowns to weight gain and found the pandemic motivated them to lose weight, but also reported decreased social support.
A global review of 121 randomised trials involving nearly 10,000 adults found herbal and dietary supplements show statistically greater weight loss but not enough to benefit health. The authors call for more research into long-term safety due to lack of clinical evidence supporting their effectiveness.
A new study by University of Copenhagen researchers reveals the key to maintaining long-term weight loss in people with obesity. Combining moderate-intensity exercise with appetite-inhibiting medication yields significant health benefits, including reduced blood sugar levels, improved fitness ratings, and muscle mass preservation.
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Researchers found that consuming mixed tree nuts resulted in significant weight loss and improved satiety, while also reducing dropout rates compared to pretzel snacks. The study suggests that incorporating tree nuts into a weight management program may have a positive impact on overall health.
A study published in JAMA Neurology found that weight loss surgery is more effective than dieting in reducing brain pressure in patients with idiopathic intracranial hypertension (IIH). Bariatric surgery resulted in a significant reduction of brain pressure and weight loss, with the surgery group losing an average of 23Kg after 12 months.
A recent study published in Nutrients investigated the influence of exercise on food intake. The results showed that physical activity increased the amount and urgency of food consumption, particularly after exercise. This finding highlights the importance of considering post-exercise eating habits for optimal weight loss.
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The American Gastroenterological Association has released new clinical guidelines recommending the use of intragastric balloons for patients with obesity who have not been able to lose weight with traditional strategies. The treatment is most successful when combined with lifestyle modifications and pharmacological agents, and can be u...
Researchers tested 17 supplements containing deterenol and found nine experimental stimulants, linked to nausea, vomiting, and cardiac arrest. Consumers are urged to avoid these products and report any adverse effects to medical authorities.
Researchers found that dieting impairs the energy-producing machinery of fat tissue, resulting in rapid weight regain, whereas bariatric surgery improves mitochondrial function and reduces regaining weight. The study used transcriptomics analysis to examine the effects of dieting and surgery on adipose tissue mitochondria.
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A pooled data analysis of 31 clinical trials found that wearable fitness trackers and step counters significantly helped people with weight-related health conditions lose weight. Those using research-grade step counters/accelerometers lost an average of 4.4 kg, while commercial fitness trackers produced a 3 kg loss.
New research from the University of Bath found that females who are physically fitter burn fat more efficiently when exercising compared to males. The study analyzed factors influencing body fat burning during endurance sports and explored molecular mechanisms behind sex differences in fuel use.
A study by the University of South Australia found that women with gestational diabetes are ten times more likely to develop type 2 diabetes. However, only a third of these women understand they are at high risk due to lack of education and lifestyle changes.
A study found that family members of patients following the Mediterranean diet-based PREDIMED-Plus program experienced significant weight loss, averaging almost 4 kg over two years. Improved dietary habits were also observed, with family members showing increased commitment to the Mediterranean diet.
Researchers found that participants with obesity and food insecurity lost less weight than their food-secure counterparts over a 24-month period, despite following an intensive lifestyle-based intervention. The study highlights the need for weight loss approaches that address both obesity and food insecurity.
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A recent international study found that semaglutide, an injectable medication, is effective in reducing weight and treating obesity in patients with Type 2 diabetes. The study showed significant weight loss results, with over 25% of participants achieving a 10% or greater weight loss.
Researchers mapped out changes in fat tissue during intermittent fasting, showing visceral 'belly' fat becomes resistant to weight loss by adapting to repeated fasting periods. The study provides insights into the mechanisms behind this resistance and potential diet interventions.
A systematic review of randomized controlled studies found that digital self-monitoring using digital health tools was associated with significant weight loss. Digital tools, including apps, wearables, and websites, were used to track behaviors such as diet and physical activity.
In a groundbreaking 68-week study, semaglutide combined with intensive behavioral therapy resulted in an average weight loss of 16% for participants, exceeding one-third who lost 20% or more of their baseline weight. The treatment also showed significant improvements in cardiometabolic risk factors and marked metabolic benefits.
A study found that bariatric surgery leads to greater weight loss in patients with a heightened perception of sweetness and lower hedonic hunger. Changes in sweet intensity perception were associated with the magnitude of weight loss, while pleasantness had no correlation.
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A new study found that a vegan diet is more effective than the Mediterranean diet for improving health markers and boosting weight loss. Participants who followed a low-fat vegan diet lost an average of 6 kg and had significant reductions in visceral fat, total and LDL cholesterol levels.
A pilot study of time restricted eating found that participants lost an average of 3.5kg over 12 weeks with almost 60% adhering to the plan at three months. The researchers suggest this weight loss approach could be a viable option for those struggling with obesity.
A University of Alberta study finds that weight loss before knee replacement surgery does not lead to better outcomes for patients with advanced knee osteoarthritis. The research calls into question the use of body mass index (BMI) as a determinant of patient outcomes, highlighting the need to reconsider recommendations about BMI.
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A low-carb diet may lead to higher rates of type 2 diabetes remission in the short term, with benefits diminishing at 12 months. The study found that low-carb diets increased weight loss and reduced medication use, but also showed worsening quality of life and cholesterol levels at longer term.
A new study found that many weight loss surgery patients in the UK are not receiving annual nutritional monitoring and weight checks as recommended by clinical guidelines. This can lead to serious health consequences, including weight regain and nutrient deficiencies. The study's lead researcher calls for improved support for GPs and p...
A Drexel University study found that health counselors with access to self-monitored health data helped participants maintain weight loss. The study involved 87 adult participants who shared their daily activity, food intake, and weight using wearable devices and smartphone apps.
A recent study found that formulating New Year's resolutions as 'approach goals' (adopting new habits) leads to higher success rates than 'avoidance goals' (quitting or avoiding something). Rephrasing resolutions can also boost success, especially when replacing unhealthy habits with healthier ones.
A new study published in the Journal of Bone and Mineral Research found that exercise can help minimize bone loss after weight loss surgery. Participants who attended structured exercise sessions had higher bone mineral density measurements compared to those in the control group.
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A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that gastric bypass surgery can lead to long-term diabetes remission in over half of adults with type 2 diabetes. The study suggests that weight loss is not the only factor contributing to improved blood sugar levels.