A new study from the University of Oklahoma found that measuring circulating microRNAs is likely as effective as measuring blood sugar levels in determining how young people with type 2 diabetes will fare. The study also found a 20% decrease in beta cell function during the first six months of treatment.
SourceUniversity of Oklahoma·JournalThe Journal of Clinical Endocrinology and Metabolism·TypeData/statistical analysis·DateJun 24, 2024
Researchers from the University of Granada found that accumulating moderate-to-vigorous physical activity in the evening improves glucose regulation in overweight and obese adults. The study's results have significant implications for individuals at risk of developing insulin resistance or type 2 diabetes, highlighting the importance o...
SourceUniversity of Granada·JournalObesity·TypeRandomized controlled/clinical trial·DateJun 14, 2024
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
A potential new strategy for reducing diabetes risk associated with antipsychotic medications involves co-administering drugs that block dopamine receptors in the brain alongside those that stop these same receptors in the pancreas. This approach may limit metabolic side effects and improve glucose metabolism.
SourceUniversity of Pittsburgh·JournalDiabetes·DateJun 13, 2024
The CCR4-NOT complex plays a crucial role in regulating RNA metabolism and stress response in C. elegans, compromising stress resistance and decreasing lifespan when depleted of subunits. This study highlights an important new role for the CCR4-NOT complex in normal aging and longevity.
SourceImpact Journals LLC·JournalAging-US·TypeCommentary/editorial·DateJun 11, 2024
Aging human pancreatic beta cells display features of senescence but maintain elevated levels of genes crucial for function and exhibit an ability to release insulin in response to glucose. This sheds light on the potential role of aging beta cells in immune regulation and their relevance to autoimmune reactions in type 1 diabetes.
SourceThe Hebrew University of Jerusalem·JournalNucleic Acids Research·TypeExperimental study·DateJun 3, 2024
A new study reveals how accumulation of IMAT drives diseases such as muscle loss, type 2 diabetes, and cardiovascular disease. Regular exercise and healthy diet can prevent and reverse IMAT accumulation.
SourceVictor Chang Cardiac Research Institute·JournalMolecular Aspects of Medicine·TypeSystematic review·DateJun 2, 2024
Researchers at the University of Rochester Medical Center found that ketones can rescue impaired neuronal function in the hippocampal network. This study suggests a potential therapeutic approach for preventing or delaying neurodegenerative diseases like Alzheimer's.
SourceUniversity of Rochester Medical Center·JournalPNAS Nexus·DateMay 31, 2024
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A new study reveals that a cancer drug can improve insulin sensitivity and lower blood glucose levels, but eliminating a specific gene related to fat metabolism worsens insulin resistance. The research highlights the interconnectedness of fat metabolism in organs and the need for simultaneous treatment of obesity and insulin sensitivity.
SourceUniversity of Oklahoma·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMay 23, 2024
Researchers at the State University of Campinas found that daily consumption of jaboticaba peel improved glucose metabolism even after meals. The study showed lower post-prandial glycemia and less inflammation in volunteers with obesity and metabolic syndrome.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalNutrition Research·DateMay 21, 2024
Researchers are exploring the connection between high-fat diets and Type 2 diabetes, with a focus on the REDD1 protein in heart cells. Insulin resistance in heart cells doubles the risk of heart failure and death, highlighting the need for new treatments for diabetic heart disease.
Researchers found that men with obesity have increased adipose tissue insulin resistance and higher levels of free fatty acids in the blood. This may partly explain why type 2 diabetes is more common in men. The study suggests that sex differences in adipose tissue insulin sensitivity could be a key factor in this disparity.
SourceEuropean Association for the Study of Obesity·JournalInternational Journal of Obesity·DateMay 10, 2024
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Neotame has been shown to cause previously healthy gut bacteria to become diseased and invade the gut wall, potentially leading to irritable bowel syndrome and sepsis. The study also found a breakdown of the epithelial barrier, which forms part of the gut wall.
SourceAnglia Ruskin University·JournalFrontiers in Nutrition·DateApr 24, 2024
Researchers found that spinal cord injury triggers abnormal neuronal activity that causes abdominal fat tissue compounds to leak and pool in the liver and other organs. A short course of gabapentin, commonly prescribed for nerve pain, prevented this damaging metabolic effect.
SourceOhio State University·JournalCell Reports Medicine·TypeExperimental study·DateApr 24, 2024
A new study has identified a deficit in the placental expression of IGFBP1 and low circulating levels as associated with insulin resistance during pregnancy. The findings suggest that measuring IGFBP1 levels could help identify people at risk of developing gestational diabetes early in pregnancy.
SourceHarvard Pilgrim Health Care Institute·JournalNature Medicine·DateApr 16, 2024
Scientists at University of California San Diego discover how one TZD drug works and replicate its benefits in mice without side effects. Researchers identify specific microRNA responsible for beneficial metabolic effects, paving the way for potential new therapies for type 2 diabetes.
SourceUniversity of California - San Diego·JournalNature Metabolism·DateApr 11, 2024
A new study found that increased childhood sedentary time is associated with higher blood insulin concentration and a greater risk of excess insulin and insulin resistance. Light physical activity was shown to reduce the risk of excess insulin by 20%, while moderate-to-vigorous physical activity had a smaller effect.
SourceUniversity of Eastern Finland·JournalThe Journal of Clinical Endocrinology and Metabolism·DateApr 9, 2024
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A review of mitochondrial energy metabolism in diabetic cardiomyopathy reveals disrupted dynamics and oxidative stress as key triggers. Targeted therapies, such as antioxidants and ketogenic diets, show promise in combating this debilitating condition.
SourceCactus Communications·JournalChinese Medical Journal·TypeLiterature review·DateApr 4, 2024
A low-fat vegan diet was found to reduce insulin needs by 28% and improve insulin sensitivity by 127% in people with type 1 diabetes, according to a groundbreaking new study. The diet also led to improvements in cholesterol levels, kidney function, and weight.
SourcePhysicians Committee for Responsible Medicine·JournalClinical Diabetes·TypeRandomized controlled/clinical trial·DateMar 29, 2024
A recent literature review discusses the underlying mechanisms of type 2 diabetes, including insulin resistance and b-cell failure. The review also explores potential therapeutic strategies, such as replenishing and regenerating b-cells, pancreas transplants, and stem cell-derived b-cells.
SourceCactus Communications·JournalChinese Medical Journal·TypeLiterature review·DateMar 19, 2024
Researchers found that Kallistatin expression increases after weight loss, improving hepatic insulin sensitivity in obese mice. This protein may be an interesting therapeutic target for treating obesity and type 2 diabetes.
SourceDeutsches Zentrum fuer Diabetesforschung DZD·JournalMolecular Metabolism·TypeObservational study·DateMar 18, 2024
A one-year interdisciplinary therapy program reduced inflammation and cardiometabolic risk in obese adolescents, improving insulin resistance and weight management. The semi-intensive model produced better results than previous intensive models, reversing hyperlipidemia and promoting energy balance.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalInternational Journal of Environmental Research and Public Health·DateFeb 21, 2024
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
A fasting-mimicking diet has been shown to reduce signs of immune system aging, insulin resistance, and liver fat in humans, resulting in a lower biological age. The study found that patients who followed the diet had lower disease risk factors and improved immune function.
SourceUniversity of Southern California·JournalNature Communications·TypeRandomized controlled/clinical trial·DateFeb 20, 2024
A new study from the University of Surrey found that melatonin treatment significantly improved sleep quality in night shift workers, but had no effect on insulin resistance or glucose tolerance. The research suggests that alternative methods to improve insulin resistance and reduce the risk of Type 2 diabetes may be needed.
SourceUniversity of Surrey·JournalPharmacological Research·DateFeb 19, 2024
Millennial-aged adults who snack on pistachios and other tree nuts experience better weight control and more efficient use of dietary fat as an energy source. The study's results support the inclusion of tree nuts as part of a healthy self-care routine in 2024.
SourceAmerican Pistachio Growers·JournalNutrients·TypeRandomized controlled/clinical trial·DateFeb 7, 2024
A recent study published in PNAS suggests that impaired macrophage function plays a key role in the development of type 2 diabetes in obese individuals. The research found that collagen breakdown is handled by macrophages, which become deactivated in obesity and insulin resistance, leading to the accumulation of collagen fragments.
SourceUniversity of Gothenburg·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateFeb 1, 2024
A new study found that curtailing sleep by 90 minutes for six weeks increased insulin resistance in women, particularly postmenopausal women. Insulin resistance was also linked to an increased risk of developing type 2 diabetes.
SourceColumbia University Irving Medical Center·JournalDiabetes Care·TypeExperimental study·DateNov 13, 2023
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
A recent study found that chronic insufficient sleep can increase insulin resistance in healthy women, with more pronounced effects on postmenopausal women. Insulin resistance can lead to a higher risk of developing type 2 diabetes.
SourceNIH/National Heart, Lung and Blood Institute·JournalDiabetes Care·DateNov 13, 2023
A preclinical study by Weill Cornell Medicine researchers reveals that activating a pathway to promote cell division can expand insulin-producing cells without impairing their function. The study's findings support the concept that beta cell mass can be expanded without compromising function.
SourceWeill Cornell Medicine·JournalJournal of Clinical Investigation·DateNov 8, 2023
Researchers found that a high-sugar diet causes insulin resistance in the brain, reducing its ability to remove neuronal debris and increasing the risk of neurodegenerative diseases. This study provides insight into how obesity-inducing diets contribute to disease risk.
SourcePLOS·JournalPLOS Biology·TypeObservational study·DateNov 7, 2023
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
A recent study published in Nutrients found that daily strawberry consumption can improve cognitive performance and reduce depressive symptoms in middle-aged adults. The research, led by Professor Robert Krikorian, suggests that strawberries contain antioxidants and micronutrients that may help mitigate the risk of dementia.
SourceUniversity of Cincinnati·JournalNutrients·TypeRandomized controlled/clinical trial·DateNov 1, 2023
Nick Burton's research aims to identify bacteria that influence insulin production and signaling, with the goal of finding new therapeutic strategies for Type 2 diabetes. Preliminary results from a small-scale pilot study are promising, suggesting that certain bacteria may play a role in regulating insulin levels.
A study published in Diabetes Care found that obesity, hypertension, and dyslipidemia alter cardiac energy production by interfering with metabolic substrate uptake. The research reveals early changes in apparently healthy middle-aged individuals, highlighting the importance of identifying mechanisms involved in heart disease onset.
SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalDiabetes Care·TypeRandomized controlled/clinical trial·DateOct 3, 2023
A groundbreaking study by UNIST researchers reveals that high levels of endotrophin in fat cells disrupt autophagy, leading to inflammation and insulin resistance. Inhibiting ATG7 protein function or neutralizing endotrophin shows promise as a potential treatment for obesity-related metabolic diseases.
SourceUlsan National Institute of Science and Technology(UNIST)·JournalMetabolism·DateSep 7, 2023
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Researchers discovered a gut bacteria that helps reduce insulin resistance and protect against diabetes. The study found that a specific bacteria, Alistipes indistinctus, consumed excess monosaccharides in the gut, lowering blood sugar levels and reducing insulin resistance.
A new study from the University of Copenhagen reveals that GDF15 improves insulin sensitivity in rodents, particularly in their liver and fatty tissue. This finding raises interesting perspectives for treating type 2 diabetes and high blood pressure, as increased insulin sensitivity is a critical indicator of health.
SourceUniversity of Copenhagen - Faculty of Science·JournalCell Metabolism·DateAug 28, 2023
A new study found that arterial stiffness is a novel cause of premature heart damage among adolescents, leading to increased blood pressure and insulin resistance. The study discovered that adolescents with high arterial stiffness had a 23-27% increased risk of structural heart damage.
SourceUniversity of Eastern Finland·JournalAtherosclerosis·DateAug 15, 2023
Researchers at Buck Institute for Research on Aging developed a bioavailable compound that selectively inhibits free radical production in mitochondria, preventing and treating metabolic syndrome in mice. The compound, S1QEL1.719, decreases fat accumulation, improves glucose tolerance, and normalizes fasting insulin levels.
SourceBuck Institute for Research on Aging·JournalFree Radical Biology and Medicine·TypeExperimental study·DateJul 9, 2023
Researchers have found a hidden mechanism connecting cancer and diabetes, where cancer cells don't respond well to insulin, leading to faster cancer growth. Insulin resistance can also cause muscle loss and strength decline in cancer patients.
SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalActa Oncologica·TypeMeta-analysis·DateJun 20, 2023
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
A new study suggests that eating more calories earlier in the day may improve metabolic health by reducing blood sugar fluctuations and inflammation. The study found that participants who followed an early time-restricted feeding pattern experienced a decrease in time above normal blood glucose levels, thereby improving metabolic health.
SourceNYU Langone Health / NYU Grossman School of Medicine·DateJun 15, 2023
A review of studies found that reducing meal frequency and cutting out late-night snacks can improve insulin resistance, brain health, and glycemic control. This approach may also help regulate appetite hormones and reduce calorie intake, ultimately staving off obesity and metabolic disorders.
SourceUniversity of Georgia·JournalNutrients·DateJun 15, 2023
Researchers have identified a number of candidate genes that may drive the development of conditions like Type 2 Diabetes. The study found that proteins such as PCSK1, SUR1 and GLUT2 play a role in calcium ion dynamics and insulin secretion.
A study of over 55,000 people identified new genetic variants associated with insulin resistance after eating, which may help inform future treatments of type 2 diabetes. The discovery highlights the importance of understanding how glucose regulation works in the body, particularly in the fed state.
SourceUniversity of Cambridge·JournalNature Genetics·TypeExperimental study·DateJun 8, 2023
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Researchers have developed biodegradable hollow nanoscavengers that target reactive oxygen species to restore liver function and reverse insulin resistance in human liver cells and diabetic mice. This innovative approach offers a promising pathway toward long-term treatment of type 2 diabetes and other metabolic diseases.
SourceAmerican Chemical Society·JournalACS Nano·DateMay 17, 2023
A new study found that overweight boys tend to have lower testicular volume, putting them at risk for infertility in adulthood. The research suggests that weight loss could help patients avoid infertility later in life.
SourceOxford University Press USA·JournalEuropean Journal of Endocrinology·TypeData/statistical analysis·DateMay 10, 2023
Researchers identified a novel high RS gene, SSIIIb, which when combined with the loss-of-function SSIIIa gene, increased RS content in cooked rice. This breakthrough provides genetic resources for breeding high-RS rice varieties, potentially reducing obesity and related health issues.
SourceChinese Academy of Sciences Headquarters·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMay 8, 2023
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
Recent cluster analyses identify novel risk stratification concepts to better implement precision medicine in clinical practice. Metabolically unhealthy individuals, regardless of weight, face a higher CVD risk compared to obese, metabolically healthy peers.
SourceDeutsches Zentrum fuer Diabetesforschung DZD·JournalThe Lancet·TypeLiterature review·DateMay 8, 2023
The National Institutes of Health recognizes World Asthma Day and highlights innovative research on asthma, its causes and treatments. Several NIH institutes conduct and support asthma-related research, including NIEHS, NHLBI, and NIAID.
SourceNIH/National Institute of Environmental Health Sciences·DateMay 2, 2023
Researchers found that women with prediabetes after pregnancy had aberrations in their early pregnancy blood serum metabolomic profile, including higher concentrations of small HDL particles. These metabolic changes predicted prediabetes at postpartum and were associated with increased risk of type 2 diabetes.
SourceUniversity of Turku·JournalMetabolomics·DateApr 19, 2023
A team of researchers from Ohio University discovered that CIDEC protein improves vascular and metabolic dysfunction, reducing insulin resistance and lipid levels in high-fat diet-induced mice. The study contributes to understanding the role of the vascular endothelium in regulating systemic metabolism.
SourceOhio University·JournalDiabetes·TypeExperimental study·DateMar 29, 2023
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Two new subtypes of insulin-producing beta cells, ß <sub> HI </sub> and ß <sub> LO </sub>, have been identified with distinct characteristics. The study suggests epigenetic dosage as a driving force behind the decision of ß cells to become these subtypes, offering a new target for potential diabetes treatments.
SourceVan Andel Research Institute·JournalCell Metabolism·TypeExperimental study·DateMar 28, 2023
New research reveals coffee consumption may help reduce the risk of type 2 diabetes by lowering inflammatory biomarkers in the body. A study published in Clinical Nutrition found that a one cup per day increase in coffee consumption was associated with a 4-6% lower risk of T2D.
SourceKaizo·JournalClinical Nutrition·TypeData/statistical analysis·DateMar 22, 2023
A new study suggests that pregnant women who have dimmed lights and screens for three hours before sleep are less likely to develop gestational diabetes. Dim light exposure before bedtime may help regulate glucose levels, reducing the risk of this common pregnancy complication.
SourceNorthwestern University·JournalAmerican Journal of Obstetrics & Gynecology MFM·TypeObservational study·DateMar 10, 2023
A study found that time-restricted feeding improves muscle performance in obese fruit flies by upregulating genes related to glycine production and utilization. This approach may provide a natural alternative therapy for managing obesity-related pathologies.
SourceUniversity of Alabama at Birmingham·JournalNature Communications·TypeExperimental study·DateMar 3, 2023
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Researchers found that alternate-day fasting combined with exercise decreased liver fat, weight, and ALT enzymes in patients with nonalcoholic fatty liver disease. The study suggests that this lifestyle modification may be a good option for treating the condition without pharmaceuticals.
SourceUniversity of Illinois Chicago·JournalCell Metabolism·TypeRandomized controlled/clinical trial·DateFeb 14, 2023
Researchers from DZD and Harvard Medical School identified key hepatokines dysregulated in NAFLD, predicting type 2 diabetes and cardiovascular events. Hepatokine cluster analysis revealed distinct subtypes of people with fatty liver having different pathomechanisms of insulin resistance.
SourceDeutsches Zentrum fuer Diabetesforschung DZD·JournalCell Metabolism·DateFeb 7, 2023
Researchers found that clearance of p16Ink4a-positive cells did not impact β-cell mass, but improved β-cell function and proliferative capacity in a subset of HFD mice. The targeted subpopulation of β-cells is non-proliferative and non-SASP producing.
SourceImpact Journals LLC·JournalAging-US·TypeExperimental study·DateJan 31, 2023
Researchers at WashU Medicine discovered a link between obesity and diabetes, highlighting the importance of an enzyme in fatty acid processing. The study suggests that defects in this enzyme contribute to insulin hypersecretion and beta cell failure, paving the way for potential therapeutic interventions.
SourceWashU Medicine·JournalCell Metabolism·TypeExperimental study·DateJan 11, 2023
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
A cluster randomized controlled trial found that Texas Sprouts, a gardening, nutrition, and cooking intervention, improved glucose control and reduced bad cholesterol in high-risk youth. The results showed a 0.02% reduction in mean blood sugar levels and a 6.4 mg/dL reduction in bad cholesterol.
SourceUniversity of Texas Health Science Center at Houston·JournalJAMA Network Open·DateJan 10, 2023
A recent study shows that eight weeks of exercise can restore the brain's insulin sensitivity in severely overweight adults, leading to improved metabolism and reduced visceral fat. This opens up new therapeutic possibilities for reducing obesity and diabetes risk factors.
SourceDeutsches Zentrum fuer Diabetesforschung DZD·JournalJCI Insight·TypeObservational study·DateNov 7, 2022
A new study found that afternoon or evening physical activity is associated with reduced liver fat content and improved insulin sensitivity. Performing MVPA in the afternoon or evening was linked to reduced insulin resistance by 18% and 25% respectively.