Add BrightSurf on Google Email

Aging modulates extracellular vesicles of epidermal keratinocytes

Researchers found a significant increase in extracellular vesicles released by aged keratinocytes, which were also enriched with specific microRNAs. These EVs impaired young keratinocyte proliferation and organogenesis, mimicking aged skin defects.

SourceImpact Journals LLC·JournalAging-US·TypeObservational study·DateNov 30, 2023

Coaxing hair growth in aging hair follicle stem cells

Researchers at Northwestern University have discovered a way to soften stiff hair follicle stem cells, enabling them to grow hair again. By boosting the production of microRNA-205, they promote hair growth in both young and old mice, offering potential for human hair regrowth.

SourceNorthwestern University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJun 5, 2023
SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Bryophytes branch differently… also at the molecular level

Researchers discovered that non-vascular bryophytes like Marchantia polymorpha adapt their architecture in response to shade, using phytochromes to regulate branching. The study found a liverwort-specific microRNA and SPL gene controlling meristem function, differing from vascular plants.

SourceGregor Mendel Institute of Molecular Plant Biology·JournalCurrent Biology·TypeExperimental study·DateJan 24, 2023

How genetics influences our body weight beyond the genes

Researchers have identified microRNA-7 as a non-classic genetic risk factor for hereditary obesity. The molecule affects energy balance and appetite regulation in humans and mice, highlighting the need to examine non-genetic factors in gene-based studies. This discovery may lead to new therapeutic approaches for treating obesity.

SourceETH Zurich·JournalNature Communications·TypeExperimental study·DateOct 11, 2022

New sleep molecule discovered: “It shows just how complex the machinery of sleep is”

Researchers have discovered a new sleep molecule, microRNA-137 (miR-137), that regulates hypocretin levels for normal sleep. The study found that miR-137 is associated with hypocretin regulation and sleep disorders such as narcolepsy and insomnia.

SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateApr 29, 2022

NYU, Rockefeller researchers find complexity of regulation by microRNA genes

Researchers at NYU's Center for Comparative Functional Genomics have discovered a complex system of microRNA gene regulation, with individual genes controlling an average of 200 different transcripts. The team developed PicTar, a new algorithm to predict microRNA target sites in the genome, and made several experimental validations.

SourceNew York University·JournalNature Genetics·DateApr 4, 2005
Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.