Articles tagged with Glucose
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A newly engineered yeast strain can simultaneously consume glucose and xylose, reducing inefficiencies in current biofuel production methods. The new strain produces more ethanol and consumes less time than existing strains, making it a significant breakthrough in cellulosic biofuel production.
Researchers found that drinking sweetened lemonade boosted glucose levels, reducing aggressive behavior in college students. The study suggests a link between low glucose metabolism and increased aggression and violence, particularly among individuals with diabetes.
Researchers discovered SRC-1, a steroid receptor coactivator, plays a crucial role in regulating the liver's glucose production. The study found that mice lacking SRC-1 have impaired glucose production, leading to hypoglycemia.
Researchers have trained bacteria to efficiently convert sugars in agricultural bio-wastes into valuable chemicals for bioplastics. The optimized process enables the production of high-quality bioplastics from waste materials, reducing costs and increasing efficiency.
Australian scientists have developed a measure to assess embryo health and likelihood of successful pregnancy in IVF treatment. The research found that embryos with higher glucose uptake are healthier and more likely to result in successful pregnancies, with women's embryos consuming more glucose than men's.
Scientists have found a key protein regulating biological clocks also regulates glucose production in the liver, improving diabetic mice health. Altering this protein can open new treatments for obesity and type 2 diabetes.
Researchers at NIH used high-resolution microscopy to understand how fat cells absorb glucose in response to insulin. The findings may aid in identifying the interval when someone becomes at risk for developing type 2 diabetes.
A study by researchers at the University of Warwick has found that short sleep duration is associated with a significant increased risk of developing type 2 diabetes and heart disease. People who sleep less than six hours a night are three times more likely to develop impaired fasting glycaemia, a pre-diabetic state.
Researchers found that hormonal changes play a significant role in enabling the crabs to make their journey. The Crustacean Hyperglycaemic Hormone (CHH) enables the efficient use of stored energy and its conversion to glucose to fuel the migration.
Research found high glucose levels can form a 'sugar coating' that blocks immune receptors, increasing the risk of chronic bacterial and fungal infections in diabetes patients. This can lead to increased risks of viral infections like influenza and inflammatory conditions like cardiovascular disease.
Researchers identified a novel protein called SNARK, which plays a key role in regulating glucose transport during muscle contraction and exercise. The study shows that SNARK mediates contraction-stimulated glucose transport, providing an alternative pathway for increasing glucose uptake in individuals with insulin resistance.
A bioengineered implantable glucose sensor successfully monitored tissue glucose levels in animals for over a year, demonstrating its potential as an alternative to traditional glucose monitoring methods. The device could help people with diabetes adjust their insulin doses and reduce the risk of hypoglycemia.
A Tel Aviv University study finds that women who fail the glucose challenge test have a nearly 50% chance of developing Type II diabetes within ten years. The test's predictive power highlights the need for personalized counseling and intervention to prevent disease onset.
Researchers found a significant association between acute illness complicated with hyperglycaemia and the development of type II diabetes or glucose intolerance. Patients with hospital-acquired hyperglycaemia during critical illness are at increased risk of developing diabetes, suggesting regular monitoring is necessary.
In a study of over 10,000 adults with type 2 diabetes, intensive glucose control did not delay the progression to kidney failure, major vision loss, or advanced peripheral neuropathy. However, it reduced signs of damage, such as decreased protein leakage in urine and lower cataract surgery rates.
A national study called HEALTHY found that innovative PE programs, healthier food choices, and in-class lessons on healthy lifestyles can benefit children most at-risk for type 2 diabetes. After three years, students in intervention schools had a 21% lower rate of obesity and improved fasting insulin levels compared to comparison schools.
The DURATION-2 study found that once-weekly exenatide improved HbA1c levels by 1.5% compared to 0.9% for sitagliptin and 1.2% for pioglitazone, with significant weight loss in the exenatide group. The findings suggest that exenatide should be considered as an adjunct to metformin for improving glucose control and weight loss.
A laboratory study found that fructose makes fat cells in belly fat more mature and less responsive to insulin. The findings suggest a link between high fructose intake during childhood and increased visceral obesity, which raises cardiometabolic risk.
A University of Pennsylvania psychologist reanalyzes data suggesting that the brain does not consume extra glucose when exerting self-control, contradicting a popular model. The analysis also suggests that any potential decrease in glucose levels may be due to other factors, such as increased heart rate.
Research published in Archives of Disease in Childhood found that giving infants a small amount of sucrose or glucose before immunization significantly reduced crying and pain. Healthcare professionals are recommended to consider using these solutions as an analgesic during painful procedures.
A new study found that just one night of short sleep duration can cause significant changes in metabolic regulation, leading to impaired glucose tolerance and insulin resistance in healthy individuals. Researchers used the hyperinsulinemic euglycemic clamp method to measure insulin sensitivity before and after a night of either normal ...
Researchers found significant differences in hemoglobin A1c response to blood glucose between African-American and Caucasian children with diabetes. The study suggests that doctors may be misinformed about blood glucose levels in African-American patients, leading to life-threatening hypoglycemia and increased complications.
A new study by Duke University Medical Center scientists identifies a mechanism linking meal anticipation to Type 2 diabetes. Ankyrin-B gene mutation impairs insulin secretion, increasing blood sugar levels.
Researchers found that HbA1c levels accurately predict future diabetes and stroke, heart disease, and all-cause mortality. The study identified people with HbA1c levels between 5.0 to 5.5 percent as within the normal range, while those at a level of 6.5 percent or greater are considered diabetic.
A team of LMU researchers has created a genetically modified strain of pigs that consistently develop the essential symptoms of type 2 diabetes. The pigs' physiology is similar to humans', making them an ideal model system for studying the disease, testing new treatments and diagnostic methods.
A closed-loop 'artificial pancreas' system can improve blood sugar control in young patients with type 1 diabetes, reducing the risk of nocturnal hypoglycaemia and achieving good glucose levels. The study found that children with the artificial pancreas maintained normal blood glucose levels for 60% of the time.
Researchers at the Salk Institute have discovered that corticotropin-releasing factor (CRF) plays a part in the pancreas, increasing insulin secretion and promoting beta cell division. This finding may provide new insights into diabetes, particularly type 1, and suggest novel targets for drug intervention.
A study reveals that the absence of SIRT6 triggers a switch from cellular respiration to glycolysis, leading to increased glucose uptake and reduced mitochondrial energy production. This switch may contribute to tumor growth and provide new insights into treating type 2 diabetes.
Researchers at University of Florida have developed a tiny new sensor that can detect glucose levels in the breath and pH levels, offering a potential solution for non-invasive diagnosis and treatment. The sensor is made from widely used technology already in cell phones and other devices, making it inexpensive to produce.
Two large-scale studies found 13 new genetic variants influencing blood glucose regulation, insulin resistance, and beta cell function. Five variants increase the risk of type 2 diabetes, highlighting the role of beta cells in disease development.
A team of researchers identified ten new genetic markers associated with biological traits underlying type 2 diabetes and three new variants linked to raised glucose levels. The study helps unravel the complex biology of type 2 diabetes and paves the way for further research on treatments.
A major international study has identified 10 new gene variants associated with blood sugar or insulin levels, including two that increase type 2 diabetes risk. The study provides additional information on glucose regulation and potential therapeutic targets for the disease.
A study conducted by the University of Chicago found that obstructive sleep apnea (OSA) significantly worsens glucose control in patients with type 2 diabetes. OSA severity is associated with poorer glycemic control and increased HbA1c levels, which can negate the effects of anti-diabetic medications.
Researchers developed non-invasive technology using nanoparticles that react with glucose molecules in tears, changing color to alert users. The innovation has potential applications beyond biomedical devices, including food packaging and biodegradable materials.
Researchers at UAB have discovered that restricting glucose consumption can extend the life of healthy human-lung cells and speed the death of precancerous cells. The study found that calorie reduction aids the body's natural ability to kill off cancer-forming cells through epigenetic control of telomerase and p16 expression.
Researchers at the University of North Carolina found genetic variations that lead to less efficient glucose metabolism in African-American patients compared to whites. These findings suggest a link between diet and environment in shaping genetic predispositions to diabetes.
Researchers found that gestational glucose intolerance during pregnancy predicts an increased likelihood of metabolic syndrome at 3 months postpartum. This study suggests women with this condition may be at high risk for future cardiovascular disease.
Researchers found that good taste and pleasant meals stimulate muscle glucose uptake and decrease blood glucose levels. Orexin is involved in the regulation of muscle glucose metabolism, suggesting a potential role in controlling feeding behavior and blood sugar levels.
Researchers at Winship Cancer Institute have discovered a common switch governing cancer cells' glucose usage, which could lead to new treatments.
Dr. Bergman's work developed a glucose 'disposition index' that quantifies the nature of interactions between insulin sensitivity and pancreatic secretion, predictive of type 2 diabetes development. The awards ceremony recognizes his contributions to understanding carbohydrate metabolism and identifying risk factors for type 2 diabetes.
Scientists discovered that adding glucose to worms' diet reduces their life span by 20%, suggesting a possible link between sugar and human aging. The study highlights the importance of insulin signaling pathways in regulating life-extending molecular players.
Researchers at Brigham Young University have developed a fuel cell that extracts electrons from glucose and other carbohydrates, utilizing a common weed killer as a catalyst. The technology has shown a 29% conversion rate, paving the way for more efficient and commercially viable applications.
Researchers found that kudzu root's isoflavones, particularly puerarin, improve regulation of metabolic syndrome contributors. The substance regulates glucose in the blood by steering it to beneficial places like muscles, away from fat cells and blood vessels.
A large cohort study suggests that mild glucose intolerance in pregnancy may be an early indicator of women at increased risk of heart disease. Women with subclinical blood vessel changes during pregnancy are more likely to develop type 2 diabetes and vascular disease.
Researchers at Huntsman Cancer Institute have discovered that restricting glutamine availability can halt tumor growth by blocking glucose utilization. This breakthrough could lead to the development of new drugs targeting glutamine utilization or MondoA/ TXNIP.
Researchers at Duke University Medical Center found that carnitine supplementation improves glucose tolerance in obese rats by restoring their cells' fuel-burning capacity. This breakthrough offers potential therapy options for people with type 2 diabetes, prediabetes, and kidney disease.
A novel function of a gut hormone was discovered that can potentially lower glucose levels in diabetes by activating specific receptors. The study found that CCK peptide hormone rapidly lowers blood glucose by triggering a signal to the brain and liver.
Researchers found that a gut hormone called cholecystokinin (CCK) activates receptors to regulate glucose levels via a gut-brain-liver neuronal axis. CCK's effects depend on activation of CCK-A receptors, which slow down glucose production in the liver.
A study published in the Archives of Internal Medicine found that intensive glucose control halves the rate of eye and kidney damage in people with longstanding type 1 diabetes. The study also showed lower rates of cardiovascular disease events and improved vision loss rates compared to conventional control.
Researchers at the University of Illinois have developed a new method using electrolyzed water to pretreat ethanol waste products, producing an acetone-butanol-ethanol fuel mix. The traditional chemical-based method is eliminated, reducing inhibitor production and increasing sugar yield.
Researchers found that diabetic patients with heart failure who have blood glucose levels slightly higher than recommended have the lowest risk of death. In contrast, those with levels too high or too low are at increased risk of mortality.
A study published in The Journal of Bone and Joint Surgery found that controlled glucose levels significantly reduce complications after total joint replacement surgery for diabetic patients. Patients with uncontrolled glucose were more likely to experience surgical complications, infection, blood transfusions, and longer hospital stays.
The glucose challenge test is an accurate, convenient, and inexpensive way to screen the general population for unrecognized diabetes and prediabetes. The study screened 1,573 participants and found that 4.6% had previously unrecognized diabetes and 18.7% had prediabetes.
A study published in The Lancet found that metabolic changes, including increased fasting glucose levels and decreased insulin sensitivity, occur several years before the onset of type 2 diabetes. By identifying these changes, it may be possible to delay or even prevent diabetes diagnosis.
A recent phase II study found aleglitazar to be safe and well-tolerated, reducing HbA1c levels in patients with type 2 diabetes. The medication also showed a favorable lipid profile without significant cardiovascular risks.
Researchers found that routine diabetes screenings can lead to significant cost savings for healthcare systems. The study suggests that screening and preventive management can be a cost-effective approach to managing the disease.
Researchers at UCLA's Brain Injury Research Center are re-examining the standard treatment for traumatic brain injury (TBI), suggesting that fueling the brain with glucose may not be the best approach. Instead, they propose using alternative compounds like pyruvate and beta-hydroxybutyrate to optimize recovery.
A Finnish study found that low glycogen levels predict forthcoming violent offending among antisocial male offenders. Low glycogen stores may contribute to impulsive violent behavior during alcohol intoxications.
A special supplement of Diabetes Technology & Therapeutics reviews the latest research findings and critical analysis of continuous glucose monitoring (CGM) technology. CGM devices have been shown to improve glucose control, but limitations and drawbacks include finicky technology and limited physician knowledge.
Researchers at UCSF have identified a specialized protein called CHC22 that controls the formation of GLUT4 storage compartments in human muscles. This discovery highlights key differences between humans and mice and has implications for developing better models for studying type 2 diabetes.