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Tiny brain bubbles carry complete codes

Scientists discovered that tiny brain bubbles called small extracellular vesicles carry more complete instructions for altering cellular function than previously thought. Researchers found nearly 80% of identified mRNAs were full-length, allowing them to be transcribed by recipient cells into viable proteins.

SourceSanford Burnham Prebys·JournalCell Reports·TypeExperimental study·DateApr 8, 2024

Cellular postal service delivers messages from non-human cells, too

Extracellular vesicles have been found to transport bacterial products into human cells, alerting the immune system and potentially affecting physiology. This discovery explains a key mechanism by which bacteria impact our health, with implications for both infections and normal bodily functions.

SourceUniversity of Connecticut·JournalNature Cell Biology·TypeExperimental study·DateNov 27, 2023
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Researchers discover how some brain cells transfer material to neurons in mice

Researchers at UC Davis discovered how oligodendrocyte-lineage cells transfer cell material to neurons in the mouse brain, providing a new mechanism for understanding brain maturation and finding treatments for neurological conditions. This discovery opens new possibilities for treating neurodegenerative diseases like Alzheimer's and P...

SourceUniversity of California - Davis Health·JournalJournal of Experimental Medicine·DateApr 17, 2023

Purification of DNA nanostructures from hydrophobic aggregates

Researchers developed a simple purification method using surfactants to separate hydrophobic DNA nanostructures from aggregates, enabling the construction of artificial cells and complex functions in molecular robots. The purified structures retain their ability to bind lipid vesicle surfaces.

SourceKyutech·JournalChemBioChem·DateMar 6, 2023

The changing patterns of DNA microcapsules

Researchers at Tohoku University have successfully created capsule-like DNA structures using two different types of nanostructures that can stick together. These structures can form water-in-oil droplets with patch-like patterns depending on the concentration of each type, and can be used to carry substances to specific target organs o...

SourceTohoku University·JournalJournal of the American Chemical Society·DateDec 12, 2021