Articles tagged with Molecular Chemistry
Researchers from Drexel University found that microbes help break down biodegradable materials and release per- and polyfluoroalkyl substances (PFAS) into the environment. PFAS have been linked to serious health problems and accumulate in soil, crops, and groundwater.
Researchers discover abiotic peptide chain formation from glycine in space conditions, shedding light on the origin of life. The study shows that small clusters of glycine molecules exhibit polymerization upon energy input.
The study uses artificial intelligence to generate new molecules with optimized properties, applicable to various industries. The method enables finding Pareto-optimal solutions, leading to more efficient materials for optoelectronics, solar energy, and other fields.
Researchers developed new spiro-pyrazolo quinazoline derivatives with reduced bee toxicity without compromising insecticidal activity. The compounds showed promising results, including one compound with an LD50 value three to four orders of magnitude lower than fipronil.
Researchers from Osaka University have stabilized atomic carbon for common reaction conditions in organic chemistry, enabling the synthesis of complex drugs in one step. This breakthrough simplifies and lowers the cost of pharmaceutical synthesis.
Researchers have used a technique called QCM-D to observe the interplay between hydration structures and ion configurations in layered materials. The study found that the hydration structure plays a crucial role in determining the material's ion-storage capacity, with flexible layers helping to stabilize the structure.
A study by University of Liège researchers decodes the mechanical response of synthetic small-molecule overhand knots to tightening, revealing a high resisting force and relative rigidity. The results have relevance for designing extended knotted and molecularly woven materials.
A multidisciplinary team led by Northwestern University has developed an electric motor that can convert electrical energy into unidirectional motion at the molecular level. The motor's design is based on a catenane molecule and has the potential to make a huge difference in medicine, particularly in biomolecular motors in the human body.
Researchers at Rice University have developed a multiplex base-editing platform that significantly improves the pace of new drug discovery by inducing fungi to produce more bioactive compounds. The technique has been deployed as a tool for mining fungal genomes for medically useful compounds, reducing research timeline by over 80%.
Researchers at Rice University have developed a photochemical process that simplifies the manufacture of essential precursors for drugs and agricultural chemicals. By illuminating reagents with visible light, they can form diazides in conditions far gentler than current industrial processes.
University of Copenhagen researchers made a groundbreaking discovery about the mammalian brain, finding that a vital enzyme that enables brain signals is switching on and off at random intervals. This challenges the long-held assumption that these enzymes are active at all times to convey essential signals continuously.
Researchers at UC San Diego have shown that vibrational polaritons alter molecular dynamics, leading to changes in chemical reactions. The study uses 2D infrared spectroscopy to separately excite and follow polariton modes and dark modes, revealing a new way to control reactions.
Researchers at the University of Amsterdam's Van 't Hoff Institute for Molecular Synthesis have developed a biocatalytic method to synthesize primary, secondary, and tertiary amines containing two stereogenic centers. The method uses a one-pot enzyme cascade, achieving excellent stereoselectivity and high chemical purity.
Researchers discover individual gold atoms can target specific C-H bonds in organic molecules, enabling a low-energy reaction at room temperature. This breakthrough addresses two significant challenges and paves the way for the synthesis of novel organic and metal-organic nanomaterials.
A Kyoto University research group has developed a material that effectively separates heavy water from normal water at room temperature. The discovery uses an adsorption-separation method based on copper-based porous coordination polymers, which utilize the flipping action of linkers to separate molecules.
Researchers at the University of Missouri have successfully used click chemistry to deliver radiopharmaceuticals specifically to tumors in large dogs with bone cancer, increasing effectiveness and minimizing circulation. This breakthrough could pave the way for click chemistry-based treatments for humans with cancer in the future.
A team of researchers from Johannes Gutenberg University Mainz have successfully developed a new approach to improve the way data is processed and stored. By combining chirality in spin configurations and molecules, they aim to create faster, smaller, and more efficient data storage devices.
Researchers create a material with disordered molecular structure that conducts electricity well, defying conventional theories. The material's stability and versatility make it promising for new electronic devices.
Researchers from Xi'an Jiaotong-Liverpool University found that brain stimulation combined with a nose spray containing nanoparticles can improve recovery after ischemic stroke. The treatment increased cognitive and motor functions, and weighed more quickly than those treated with TMS alone.
A joint research team from Korea and Japan developed site-specific organelle fluorescent thermometers that visualize temperature changes in almost all typical organelles. The new thermometers, called Thermo Greens (TGs), provide quantitative images of heat generation at different organelles, offering insights into cellular processes.
A POSTECH research team developed a new polymer electrolyte with different functional groups, resolving contradictions in mechanical strength and conductivity. This breakthrough enables the creation of artificial muscles that can produce fast switching and great strength.
A research group from Tokyo University of Science has discovered molecular features that govern the filling process at nanoscales, enabling finer resolutions in ultraviolet nanoimprint lithography. The findings provide valuable insights for guiding the selection and design of optimized resists for sub-10 nm resolution.
Researchers at Ohio State University have developed a new method to synthesize medicines using carbenes, reducing the need for explosive intermediates. This breakthrough could enable faster production of cyclopropanes, a key ingredient in COVID-19 treatments and other medications.
Researchers develop technique to control pH at microsites, enabling high-throughput biomolecular synthesis and enzymatic DNA synthesis. This allows for increased experimental throughput and speeding up processes in DNA synthesis.
A team of researchers from Tokyo University of Science has developed a novel multi-proton carrier complex that shows efficient proton conductivity even at high temperatures. The resulting starburst-type metal complex acts as a proton transmitter, making it 6 times more potent than individual imidazole molecules.
Researchers from Tokyo University of Science developed novel complex-peptide hybrids that induce programmed cell death in apoptosis-resistant cancer cells through paraptosis. The compounds, syn-6 and anti-6, inhibit cell death by uncoupling mitochondrial calcium uptake and inducing cytoplasmic vacuolization, leading to cell death.
Researchers at Eindhoven University of Technology accidentally discovered that adding more water to a liquid solution turns it back into a gel, and then further dilution forms another gel. The team's findings have significant implications for various fields in chemistry and biology.
Liu's three-year grant will pursue protein-derived cofactor studies to improve understanding of amino acids and their role in metabolism. The research aims to gain a quicker and more thorough understanding of amino acid function and purpose.
Researchers at Shinshu University have developed a new method to remove nanoplastics from water using apples and pectin. The study found that the method was able to remove 95% of nanoplastics in just 24 hours.
Researchers at Kyoto University have discovered a novel hydroxy-iodide (HSbOI) cluster compound with large, positively charged clusters. This finding may open up new possibilities in the design of solid-state catalysts.
Indiana University researchers have discovered the world's brightest-known fluorescent solid materials, called SMILES, which can transform liquid materials into stable crystalline solids with unprecedented brightness. The grant will help advance research on SMILES to improve existing technologies and create new ones.
Researchers have identified new biomarkers to detect non-small cell lung cancer in its early stages through a blood test, offering improved survival chances. The approach can also identify potential drug resistance, allowing clinicians to choose alternative treatment options.
Researchers have designed an iron catalyst to facilitate the olefin metathesis reaction, a widely applicable catalytic reaction for carbon-carbon double bond formation. The iron-based catalyst shows promise in reducing costs and environmental impact compared to traditional ruthenium-based catalysts.
Researchers have developed a new measurement method in molecular electronics that enables the exchange of molecules at will. This allows for the measurement of conductivities of many different molecules in succession. The method has potential applications in biosensing and advanced molecular computing.
A new study suggests that supplementing a diet with Ascidiacea, also known as sea squirts, reverses some main signs of aging in animal models. The researchers found that plasmalogens, vital to body processes, decrease with age and contribute to neurodegenerative diseases like Alzheimer's and Parkinson's.
Professor Holger Frey's innovative research aims to preserve PEGylation benefits while avoiding immune system recognition. His project RandoPEGMed seeks to create modified polymers for medicinal agents, potentially solving the problem of increasing antibody resistance.
Researchers have developed a novel method called 'dative epitaxy' for growing thin layers of crystals made from different materials on top of each other. This technique allows for the formation of special chemical bonds to fix crystal orientation, overcoming limitations of conventional and van der Waals epitaxial techniques.
Researchers have developed an eco-friendly and reusable solution for removing toxic synthetic dyes from wastewater using nanocomposite-based hydrogels. The new material, made from carboxymethyl cellulose (CMC) and graphene oxide, demonstrates high adsorption capacities and retains its effectiveness even after multiple cycles of use.
Researchers create complex mixtures of biomolecules that spontaneously form self-organized patterns in response to environmental changes. This breakthrough bridges the complexity gap between chemistry and biology.
Scientists at the University of Illinois Chicago have created a new family of environmentally safe, frost-resistant coatings that can delay the formation of frost for extended hours. These coatings can be applied to various surfaces without preconditioning or expensive surface treatments, reducing pollution and ice-related problems.
A study by CSIC researchers has discovered and synthesized molecules that inhibit the effect of heparin, a widely used anticoagulant drug. The molecules have been tested in mice with excellent results, showing potential as antidotes for heparin reversal drugs.
A research team has demonstrated the potential of a new material based on rare earths as a photonic quantum system, showing interest in europium molecular crystals for quantum memories and computers. The material enables ultra-narrow optical transitions, enabling optimal interactions with light.
Researchers at the University of Illinois used sonification to analyze data and teach protein folding, leading to a new discovery about protein folding mechanisms. Musicians collaborated with chemists to create audio-mapped visualizations that complemented traditional views, increasing intuition for experts.
Researchers at Niigata University have successfully observed the formation of an oxygen-oxygen bond in a low-valent Ru(III) complex. This breakthrough could lead to the development of more efficient water oxidation catalysts, crucial for artificial photosynthesis and sustainable energy systems.
Matthew Jones, a Rice University chemist, has won a National Science Foundation (NSF) CAREER Award to investigate the fundamental processes of nanoparticle formation. He aims to develop a mechanistic understanding of nanoparticle growth to control their size and shape, enabling advances in biomedicine, energy storage, and computing.
A team of scientists successfully constructed a supramolecular rotor inside a hollow cube-shaped zinc(II)-metallated porphyrinic cage (Zn-PB) molecule. The addition of a chemical stimulant initiates both rotary and tumbling motions, controlled by external stimuli.
Scientists at the University of Missouri study photodissociation reactions on the quantum level, revealing strong quantum effects that challenge classical 'billiard-ball' models. The research could lead to a better understanding of atmospheric chemistry and develop new theoretical frameworks.
Researchers at GIST used ultrafast X-ray pulses to study warm dense copper electrons, revealing that bonds harden before melting. The findings could improve understanding of extraordinary material properties and their underlying mechanisms.
Researchers studied electron transport through a single water molecule in a C60 cage, revealing multiple tunneling-induced excited states. The findings suggest the transition between ortho- and para-water occurs simultaneously within a minute.
Researchers at Osaka City University developed a new quantum algorithm that calculates potential energy curves of molecules without controlled time evolutions. This addresses issues with conventional quantum phase estimation algorithms, enabling parallel processing and efficient full-CI calculations.
Researchers in Japan have designed the first de novo-designed peptides that can form artificial nanopores to identify and enable single molecule-sorting of genetic material in a lipid membrane. The peptides can detect specific molecules, including DNA, and have the potential to mimic natural proteins' ability to detect specific proteins.
Researchers genetically engineer E. coli microbes to convert glucose into olefins, a type of hydrocarbon found in gasoline, using a two-step process with a catalyst. This method has potential to advance green energy technology and create sustainable biofuels.
The discovery proposes replacing carbon-hydrogen bonds with nitrogen rings, enabling faster and more efficient production of drug candidates. This breakthrough could lead to rapid creation of potent and effective medication libraries.
A Rice University undergraduate student and her mentor have synthesized the first molecule found in poppies, setigerumine I, using a three-step process at room temperature. The environmentally friendly method produced 20 milligrams of the rare extract, which could be a potential precursor for non-addictive painkillers.
Researchers used machine learning to analyze core-loss spectroscopy data, revealing connections between spectral data and material properties. The study successfully predicted intensive and extensive material properties, enabling high-throughput development of new materials.
Researchers from KIT and TU Darmstadt developed a novel sensor for gas molecules by combining a graphene transistor with a customized metal-organic coating. The sensor selectively detects ethanol and responds to neither other alcohols nor humidity.
Researchers at Goethe University Frankfurt and Bonn have synthesized molecular nano spheres made of silicon atoms, known as silafulleranes, which can encapsulate chloride ions. The discovery of these new compounds may lead to improved applications in electronics, solar cells, and batteries.
A research team has successfully fabricated single-layer tetracene molecular crystals using two-dimensional inorganic crystals as substrates. The resulting material exhibits extraordinary photostability and Davydov splitting, making it a promising candidate for OLEDs and organic photoelectric energy conversion.
A team of researchers at University of California San Diego School of Medicine discovered that GIV/Girdin plays a critical role in sperm motility, survival, and fertilization success. The protein regulates capacitation and acrosome reaction processes, essential for successful fertilization.
Researchers developed a novel block copolymer electrolyte that controls structure through electrostatic interactions, enhancing ionic conductivity. The new nanostructure enables significant enhancement in conductivity compared to typical two-dimensional structures, paving the way for safer all-solid-state batteries.