Articles tagged with Molecular Chemistry
UVA engineer Nick Vecchiarello is using a $600,000 grant to develop customized molecularly engineered surfaces for purifying protein-based drugs. The technology has the potential to reduce waste and failed batches, saving manufacturers millions of dollars while making treatments more affordable.
Researchers have observed the luminescence of an excited complex formed by two donor molecules, opening possibilities for developing simpler, more efficient OLED devices. The discovery also enables the creation of sensitive sensors capable of detecting low concentrations of explosive substances.
Researchers at OIST have synthesized a stable 20-electron ferrocene derivative, defying the traditional 18-electron rule. This breakthrough could lead to new applications in energy storage, chemical manufacturing, and sustainable chemistry.
A new study by Colorado State University outlines a path to creating advanced, recyclable plastics using natural poly(3-hydroxybutyrate) (P3HB). The breakthrough method involves stereodivergent catalysis, which enables the production of enantiopure PHAs with improved properties for various applications.
Researchers have engineered a new type of molecule that can store information at extremely low temperatures, potentially leading to ultra-high data densities and smaller storage devices. The discovery could enable the development of stamp-sized hard drives capable of storing 100 times more data than current technologies.
The DFG is establishing 13 new Collaborative Research Centres (CRC) to tackle innovative, challenging and long-term research projects. The CRCs will focus on circadian medicine, metabolic dysfunction-associated steatotic liver disease, heterostructures of molecules and 2D materials, and criticality.
A team of Cambridge chemists has developed a powerful new method for adding single carbon atoms to molecules more easily, offering a simple one-step approach. This technique targets alkenes, common in everyday products, and allows for the introduction of functional groups, enabling further versatility in molecule design.
Scientists have designed human-made molecules that self-assemble into stacked rings, allowing charge and energy to circulate freely, echoing photosynthesis. This breakthrough could lead to improved energy generation and advanced electronics.
Scientists have created a new way to store and decode data using synthetic molecules, which can be used to unlock computers with encoded passwords. The method involves designing molecules that contain electrochemical information, allowing messages to be decoded using electrical signals.
A new study from Uppsala University investigates how sleep deprivation affects biomarkers associated with cardiovascular disease. Researchers found that chronic lack of sleep increases the risk of heart problems by promoting inflammatory proteins.
Rasika Dias, a renowned chemist at UTA, has been named a 2025 fellow of the Royal Society of Chemistry for his groundbreaking contributions to chemical sciences. He is the second chemistry faculty member to receive this honor.
A new approach, GlycoCaging, delivers medicine directly to the lower gut at significantly lower doses than current treatments, potentially helping people with inflammatory bowel disease. The technique has been shown to be effective in mice and has potential for treatment in humans, as most people have the ability to activate the drugs.
Researchers developed fluorescent polyionic nanoclays that can be customized for medical imaging, sensor technology, and environmental protection. These tiny clay-based materials exhibit high brightness and versatility, enabling precise tuning of optical properties.
A recent study reveals that tropical forests are home to an incredible diversity of chemical compounds, including terpenoids and alkaloids, which could have practical implications for human health. The researchers found that tree species in higher elevations tend to use similar chemicals to protect themselves from enemies.
A new web platform, AutoSolvateWeb, developed at Emory University enables chemists of all levels to configure and execute complex quantum mechanical simulations through chatting. The free platform uses cloud infrastructure and automates software processes on the backend.
A team of researchers led by UMass Amherst discovered that imperfect polymer fillers can enhance thermal conductivity, challenging conventional wisdom. Polymers with defective fillers performed 160% better than those with perfect fillers in conducting heat.
A new study by researchers at the Institute of Science Tokyo hints that calcium ions played a crucial role in shaping life's earliest molecular structures. The team discovered that calcium dramatically alters how tartaric acid molecules link together, favoring homochiral polymers and potentially influencing the emergence of life.
A research group at Peking University discovered dopamine's role in regulating Tau's function through a novel chemoproteomic strategy. This finding deepens our understanding of dopamine's physiological and pathological roles in the human brain.
Researchers create WaaFs with high thermal stability and reversible assembly, opening avenues for gas storage, separation, and catalysis. The frameworks utilize van der Waals interactions to form robust structures, making them suitable for industrial applications.
Kayunta Johnson-Winters, a UTA associate professor of chemistry and biochemistry, has been honored as an American Society for Biochemistry and Molecular Biology fellow. Her research on F420-dependent enzymes has expanded understanding of disease proteins and paved the way for potential treatments.
Researchers at TUM have developed a novel method to purify proteins using short-wave UV light, eliminating the need for chemical reagents. The 'Azo-tag' system changes shape under light exposure, allowing for targeted purification of proteins in a more efficient and gentler manner.
Richard Willson, a University of Houston professor, has been elected Fellow of the Royal Society of Chemistry for his contributions to the chemical sciences. He has developed innovative methods to detect viruses and other biological threats using glow-in-the-dark nanoparticles.
A recent study found that polyester microdroplets can form in salt-rich environments, at low alpha-hydroxy acid concentrations, and in small reaction volumes. This expands on previous research and suggests that polyester protocells were likely more common on early Earth than previously thought.
A novel double aryne insertion strategy has simplified the production of complex thioxanthones, a type of organic compound with various industrial and medical applications. The new method enables efficient synthesis of diverse thioxanthone derivatives, including functional molecules and photocatalysts.
Researchers at Colorado State University have developed a stronger, biodegradable adhesive polymer that can replace common superglues. The new polymer, made from P3HB, offers tunable adhesion strength and is biodegradable under various conditions.
Researchers created new proteins using AI that bind to and neutralize deadly snake toxins, providing a safer alternative to traditional antivenoms. The study's results show an 80-100% survival rate in mice, offering potential benefits for people in developing countries.
Researchers at Indiana University found that bacteria secrete molecules, like coelechelin, which weaken competitors' immune systems and increase their vulnerability to phage infection. This discovery highlights the potential of phage-chemical combinations in treating antibiotic-resistant infections.
Macromolecular chemistry expert Christopher Barner-Kowollik receives Germany's best-funded research prize for his groundbreaking discoveries in photochemistry. His work challenges traditional assumptions and opens new avenues for applications in phototherapy, light-driven synthesis, and materials development.
Researchers at King's College London developed a new method to produce biofuels from fatty acids in cooking oil, making it as effective as diesel with improved efficiency. The technology uses enzymes to break down fatty acids into alkenes, reducing the need for conventional catalysts and toxic chemicals.
Researchers demonstrate key Darwinian evolution principles in self-replicating molecules, indicating evolution predates life. Competitive exclusion among these molecules curtails chemical diversification, shedding light on potential emergence of life from non-living materials.
Researchers at Maynooth University are leading a two-year study to develop non-abrasive bandages that can be sprayed onto the skin and melted away painlessly. The goal is to reduce the agony experienced by those living with Epidermolysis Bullosa, a genetic skin condition affecting over 500,000 children and adults worldwide.
SwRI researchers developed a tool to model environments expected on icy moons, accounting for organics and predicting conditions for microbial life. The project aims to constrain environmental factors and provide valuable information about ocean worlds.
A new phase-transformable membrane can precisely select CO₂ and H₂, enabling efficient gas separation. The membrane's liquid-glass-crystal states optimize its selectivity and permeability for specific gases.
The symposium features over 20 inspirational lectures by esteemed international speakers on molecular science topics. Nobel Prize laureates are among the keynote speakers, advancing cutting-edge research and facilitating interaction with the public.
Researchers at UCLA have invalidated Bredt's rule, a fundamental principle in organic chemistry that has constrained the design of molecules for pharmaceutical research. By creating anti-Bredt olefins, also known as ABOs, chemists can now generate highly unstable structures with practical value.
Recent research highlights microwave-induced synthesis as a transformative potential in drug discovery and development. This efficient technique enables rapid preparation of diverse N-heterocycles, including biologically active molecules such as pyrimidines, thiazoles, and quinolines.
A study led by Cesar de la Fuente and his team has uncovered sequences for infection-fighting molecules in the genomic data of extinct species. These ancient β-defensins may lead to the creation of new antimicrobial therapies, including antibacterial, antifungal, and antiviral treatments.
A team of researchers has developed a new membrane material that can detect and remove pharmaceutical chemicals from water at trace levels. The new approach uses a polymer membrane with an interconnected network of pores, which are designed to capture larger molecules, allowing for more effective filtration.
Researchers have developed a cost-effective and easily reproducible point-of-care testing device that can accurately measure cortisol levels in the blood. The device uses iridium oxide nanoparticles to improve stability, sensitivity, and selectivity, allowing for commercial use.
Researchers at the University of Illinois have developed a method to understand and improve light-harvesting molecules for solar energy applications. By combining AI with automated chemical synthesis and experimental validation, they were able to produce molecules four times more stable than traditional ones.
Researchers developed a one-pot process to transform aromatic ketones into esters, simplifying the reaction process, reducing reaction times, and minimizing purification steps. The method enables seven different chemical transformations and has shown notable stability and reusability, making it scalable for industrial applications.
Researchers at Tokyo University of Science discovered a natural tyrosinase inhibitor from Corynebacterium tuberculostearicum that inhibits melanin synthesis and provides an alternative to toxic hydroquinone-based products. The compound, cyclo(L-Pro-L-Tyr), exhibits low toxicity and potential benefits for hyperpigmentation treatment.
Scientists at Osaka Metropolitan University have found that single crystals of anthracene derivatives react differently when irradiated with light, holding clues for functional applications. The research team discovered non-uniform photoreactions in two of the compounds, which proceed from the edge to the center of the crystal.
Anaerobic bacteria have survived for ages in oxygen-free niches, influencing human health and environment. The 'AnoxyGen' project aims to unlock their biosynthetic potential using molecular and synthetic biology tools.
Scientists have created mirror-image cyclodextrins in the laboratory, which could make it easier to formulate and deliver complex medications. These discoveries may also lead to improved treatment of cardiovascular diseases caused by atherosclerotic plaques.
Researchers at Yokohama National University utilized machine learning and AI to predict the selectivity of chemical reactions. By analyzing molecular factors such as sterics and orbitals, they developed a method to better understand reaction mechanisms, leading to more efficient synthesis of desired products.
Researchers have discovered distinct ethanol-water molecular clusters that determine critical alcohol content ranges in various beverages. By controlling these clusters' transitions, manufacturers can maintain ideal taste while reducing alcohol concentration.
Three FAU researchers have received $1M in FDOH grants to develop innovative approaches against Alzheimer's disease. Mare Cudic aims to explore the link between glycosylation and neuroinflammation, while Ruth Tappen develops an online screening tool for older drivers with cognitive decline.
A new AI method developed by Swedish researchers can identify toxic substances based on their chemical structure, potentially replacing animal testing. The method has been shown to be more accurate and broadly applicable than existing computational tools, offering a promising alternative for environmental research and authorities.
Scientists at POSTECH create conducting polymers with exceptional electrical conductivity, rivaling graphene's performance. The breakthrough achieves ultrafast electron mobility and long phase coherence length, overcoming a major challenge in organic semiconductors.
Scientists developed a force-controlled release system harnessing natural forces to trigger targeted release of molecules, advancing medical treatment and smart materials. The breakthrough uses rotaxane technology to release multiple functional molecules simultaneously, including medicines and healing agents.
A new statistical-modeling workflow can quickly identify molecular structures of products formed by chemical reactions, accelerating drug discovery and synthetic chemistry. The workflow also enables the analysis of unpurified reaction mixtures, reducing time spent on purification and characterization.
A Scripps Research team has uncovered a simple and inexpensive way to produce quaternary carbon molecules using an iron catalyst. This breakthrough could benefit drug developers by making molecules cheaper and easier to produce at small and large scales.
A blended antioxidant supplement improved spatial learning ability and short-term memory in supplement-treated aged mice. The discovery suggests that the supplements may also prevent age-related cognitive decline in humans and mitigate muscle frailty.
A team of scientists from Pohang University of Science & Technology developed an artificial vitreous body based on alginate to treat retinal detachment. The hydrogel maintains vision post-surgery and regulates fluid dynamics within the eye, preventing recurrence and air bubble formation.
Researchers at Xi'an Jiaotong-Liverpool University developed a new method that enables the efficient production of cysteine-rich peptides and microproteins in their naturally folded 3D structure. The approach uses organic solvents to mimic nature's oxidative folding process, resulting in speeds of over 100,000 times faster than aqueous...
Researchers at NTNU's Department of Chemistry have developed a method to increase the calculation speed of chemical reactions by 30-40 times. By connecting 20 computers and optimizing data exchange, they achieved this significant improvement, enabling previously impractical calculations to be performed.
Researchers at KIT's Institute for Advanced Membrane Technology found that the interplay of hydrodynamic forces, friction, and forces of attraction and repulsion affects adsorption in membrane nanopores. This study provides basic findings with respect to water processing and may benefit ultra- and nanofiltration processes controlled by...
Researchers at the University of Gothenburg discovered how proteins deform to create efficient transport routes for electrons, powered by solar energy. This finding could lead to more efficient solar cells and batteries.
Researchers at North Carolina State University are developing a suite of performance metrics to standardize the evaluation of self-driving labs in chemistry and materials science. These metrics aim to compare different lab technologies and identify areas for improvement, ultimately advancing the field and accelerating discovery.