Researchers created a new type of microporous aerogel that overcomes limitations of conventional materials, enabling flexible and highly processable shapes. The material's flexibility arises from reversible van der Waals interactions between metal–organic polyhedra molecules.
A Kyoto University study reveals the molecular mechanism of high-density lipoprotein (HDL) production. Researchers used a new imaging method to show how ATP-binding cassette protein A1 (ABCA1) generates HDL molecules, a complex process involving the transfer of lipids into the extracellular domain.
A team of scientists has developed a protein-based therapeutic tool called Crunch to target and remove specific living cells, such as cancer cells or overactive immune cells. The new system uses the body's natural waste removal system to clear out unwanted cells, offering hope for improved treatments.
Researchers create WaaFs with high thermal stability and reversible assembly, opening avenues for gas storage, separation, and catalysis. The frameworks utilize van der Waals interactions to form robust structures, making them suitable for industrial applications.
Researchers at Kyoto University investigated the effects of two-hit stress on mice, finding that it leads to increased microglia activity, neuronal loss, and decreased brain connectivity. Microglia replacement therapy showed promise in rescuing affected mice, with female mice exhibiting higher stress resilience.
A new phase-transformable membrane can precisely select CO₂ and H₂, enabling efficient gas separation. The membrane's liquid-glass-crystal states optimize its selectivity and permeability for specific gases.
Scientists at Kyoto University's Institute for Integrated Cell-Material Sciences have discovered a protein complex that regulates phospholipid scrambling, a process important for blood clotting and unwanted cell removal. The finding could lead to new treatments for diseases like epilepsy and anemia.
A team of researchers has developed a new membrane material that can detect and remove pharmaceutical chemicals from water at trace levels. The new approach uses a polymer membrane with an interconnected network of pores, which are designed to capture larger molecules, allowing for more effective filtration.
Early porous coordination polymers (PCPs) exhibit a flexible 'soft' nature, allowing them to adjust their shape and hold more gas. This finding offers new insights into the evolution of PCPs and paves the way for future research and applications.
Researchers have successfully observed raft domains in live cells using new fluorescent probes, revealing dynamic interactions between gangliosides and cholesterol. The findings open up new avenues for investigating how toxins, bacteria, and viruses invade cells through these membrane structures.
A team of scientists found that 5hmC localizes at sites of DNA damage and repair, with TET enzymes playing a critical role in maintaining its reparative function. This discovery raises the possibility that 5hmC helps keep chromatin open for other DNA damage response proteins.
Scientists at Kyoto University developed an approach to assemble DNA origami units into larger structures by using a double layer of lipids. This method allows for more freedom of movement and interaction between origami structures, enabling them to form nanomachines such as nanomotors for targeted drug delivery
Researchers at Kyoto University developed a technique using tiny gold rods to target pain receptors and activate TRPV1, leading to desensitization and pain relief. The gold nanorods have been shown to be more efficient than magnetic nanoparticles in heat generation and activating TRPV1 receptors.
Researchers visualize pyrene linked to a single-walled carbon nanotube using high-resolution transmission electron microscopy. This breakthrough methodology could provide indispensable information on molecular interactions, enhancing the efficiency and lifespan of organic devices.
Researchers at Kyoto University successfully visualized RNA behavior within living brain tissue of mice, enabling the study of RNA distribution and its response to drugs. This breakthrough technique holds promise for accelerating the discovery and development of new drugs.
Researchers at Kyoto University discovered how nerve cells adjust to low energy environments during brain growth, shedding light on neurodegenerative disorders. They found two protein molecules that produce enzymes to allocate energy molecules for cellular survival in areas with low ATP energy concentrations.
Researchers developed an advanced imaging system to identify cells storing memory in a tiny worm, offering a new way to investigate molecular substrates of memory. The study may lead to understanding how memory loss occurs in humans and potentially develop therapies for memory disorders.
Scientists have discovered that PP4 protein oversees DNA processing during sperm and egg generation for successful fertilization. The study found that PP4's activity becomes more crucial during aging, indicating a potential role in age-related fertility declines.
Researchers at Kyoto University developed a novel method to assemble graphene into porous 3D structures, overcoming the challenge of maintaining unique material properties. The technique uses interfacial complexation with oppositely charged polymers, enabling tunable porosity and scalability for large-area films.
Researchers created a new membrane that can remove harmful greenhouse gases from the atmosphere, including carbon dioxide, at a lower cost and higher efficiency than current technologies.
Scientists at Kyoto University create porous coordination polymers (PCPs) with exterior surface grooves to repel water, allowing for stable gas storage and separation. The new materials demonstrate selectivity in isolating organic molecules from mixtures, overcoming a major drawback of traditional PCPs.
Researchers at Kyoto University's iCeMS have developed a process to create custom-designed porous coordination polymer architectures for high-efficiency, low-cost gas and liquid separation. The new method, called 'reverse fossilization,' transforms inorganic materials into organic structures with preserved shape and form.
Researchers at Kyoto University and the University of Oxford have successfully constructed a DNA motor capable of navigating a programmable network of tracks with multiple switches. The breakthrough uses DNA origami technology, allowing for autonomous nanoscale devices to produce predictable outputs based on different starting conditions.
Researchers at Kyoto University have discovered a way to create ultra-high-speed transistors and high-efficiency photovoltaic cells using terahertz pulses. The study found that exposing gallium arsenide to a single-cycle terahertz pulse increased electron density by an astonishing 1,000-fold.
Researchers at Kyoto University have designed an inexpensive new material capable of quick and accurate detection of carbon dioxide gas. The compound gives off variable degrees of visible light in correspondence with different gas concentrations, enabling the development of easy-to-use monitoring devices.
The research team used single-molecule imaging to study G protein-coupled receptors (GPCRs) and found that they can interconvert between monomers and dimers. This understanding is crucial for predicting GPCR numbers in cells and blocking signal amplification by these molecules.
A team of scientists created a programable molecular transport system, observed in real time using atomic force microscopy. The system consists of a DNA origami track with a motor and fuel, allowing for adjustable speed and potential applications in drug delivery and synthetic ribosome creation.
Researchers at Kyoto University have developed a porous framework that can capture common air pollutants and emit glowing colors when exposed to ultraviolet light. This breakthrough enables the creation of portable, solid-state pollution detectors with potential applications in medicine, pharmaceuticals, and industry.
Researchers at Kyoto University have successfully developed a method using terahertz pulses to manipulate molecular networks in crystalline form. This technique softens crystals without raising temperatures, allowing for potential advances in chemical synthesis and pharmaceutical refinement.
Scientists at Kyoto University have developed a new method to study polymers in confined spaces, revealing unexpected thermal transitions and potential breakthroughs in nanoscale manufacturing. The technique uses porous coordination polymers to trap polymers, allowing researchers to observe their behavior under controlled conditions.