A large-scale study revealed that SEEG improves decision-making in temporal lobe epilepsy by identifying specific patterns like LFPS that predict better outcomes. This enhancement enables clinicians to make more precise surgical plans, particularly for patients with non-concordant imaging or suspected bilateral epilepsy.
A bioinspired soft robotic system combines a steerable, elongating soft arm with a leech-inspired three-finger grasper to overcome limitations of existing ESD robots. The system achieves high precision, force and endurance, but requires improvements in fine force control, haptic feedback and sterilization for clinical translation.
A new study suggests that prolonged nitrate depletion delayed marine ecosystem recovery after the end-Permian mass extinction. Nitrate availability remained consistently low in South China during this period, with temperatures rising and falling to impact ocean stratification and upwelling.
A new study from Tel Aviv University found that the percentage of fat in a child's liver is a critical factor in determining their overall health, rather than just their body weight. The researchers discovered that children with lower liver fat levels were less likely to develop metabolic illnesses, even if they were obese.
Researchers created a comprehensive single-nucleus transcriptomic atlas of the pig intestine, identifying 19 major cell types and 58 cellular subtypes. This study provides valuable insights into the mechanisms by which neurons regulate inflammatory responses and the molecular basis for stronger immune functions in wild boars.
Researchers have developed a comprehensive review on thermally drawn flexible fiber sensors, which provide excellent flexibility, biocompatibility, and scalability. The thermal drawing process enables the mass production of multifunctional fiber sensors for various applications, revolutionizing wearable technology and biomedical devices.
Recent advances in cathode binder design for lithium-ion batteries focus on LiFePO4 and transition-metal oxide cathodes. The overlooked role of binders is highlighted to ensure long cycling stability, safety, and sustainability.
The SRI model integrates swarm dynamics with dynamic graph neural networks, resolving existing method pitfalls. It demonstrates significant performance improvements over traditional methods, with reduced long-term prediction errors.
Researchers have assembled a near-complete genome map of northern wild rice (Zizania palustris), spanning 1.41 Gb with 47,804 predicted genes. This improved genome provides critical insights into the plant's unique adaptations and traits, supporting future breeding and sustainable cultivation.
Researchers are developing monolithic perovskite/perovskite/silicon triple-junction solar cells to overcome the theoretical efficiency limit of crystalline silicon. The cells feature tunable bandgaps, low-cost fabrication, and excellent optoelectronic properties.
Researchers developed a new strategy to boost immunotherapy in solid tumors by targeting senescent immune cells, which contribute to treatment resistance. The approach showed improved efficacy and lower toxicity compared to existing treatments.
Researchers developed an innovative NGCs model to predict luminescence properties and design complex glass systems. The model enables the estimation of multiple luminescence metrics, allowing for rational design of chemically complex laser glasses with superior performance.
A Kyoto University study reveals the molecular mechanism of high-density lipoprotein (HDL) production. Researchers used a new imaging method to show how ATP-binding cassette protein A1 (ABCA1) generates HDL molecules, a complex process involving the transfer of lipids into the extracellular domain.
Researchers propose a novel lower-limb motion capture system using flexible pressure sensors, achieving accurate joint position estimation with an average prediction error of only 7.8 pixels. The system enables seamless interaction and natural control in the metaverse.
Scientists discovered that tree species respond differently to slope, bench, or valley in temperate forests, with some species storing more carbon on slopes than others. The study found that valleys tend to have higher biomass of yellow-poplar and American beech, while slopes support southern shagbark hickory growth.
Researchers have successfully grown the smallest stable carbon nanotubes, a breakthrough that could lead to advancements in nanoelectronics and cutting-edge technologies. The study uses rhodium-based catalysts to achieve a high yield of the (5, 4) nanotube, paving the way for future applications.
A review by Prof. Mayer Brezis reveals finasteride's potential psychiatric effects, including depression and suicidal thoughts, despite mounting evidence; hundreds of thousands may have suffered from depression, and hundreds more may have died by suicide.
Scientists developed a custom Kelvin probe force microscopy system to study the chiral-induced spin selectivity effect in chiral halide perovskites. The study reveals nanoscale 'spin maps' that show the strength and spatial uniformity of the CISS effect.
Researchers propose a self-doped molecular Mott insulator model for La3Ni2O7, connecting strong correlations and interlayer coupling to its superconducting properties. The material's unique bilayer structure leads to localized atomic orbitals forming symmetric and antisymmetric molecular orbitals.
Researchers have developed a CoWO4/WO2 heterojunction catalyst that leverages intercalation-mediated catalysis to accelerate polysulfide conversion and suppress the shuttle effect, enabling long-life lithium-sulfur batteries.
A new Cochrane review finds RSV vaccines reduce the risk of infection in vulnerable groups, including older adults and infants. Vaccination also significantly reduces severe disease and hospitalization rates.
New Cochrane review finds RSV vaccines protect against severe lung infections in high-risk groups. Vaccination with RSV prefusion vaccines reduces lower respiratory tract disease by 77% in older adults, while pregnant people's children benefit from reduced hospitalization risk by 54%.
A pilot study found that hypnosis significantly improved patients' tolerance of masks, allowing them to breathe more comfortably. The study showed a substantial improvement in non-invasive ventilation (NIV) tolerance, reduced agitation, and lower requirements for sedation and anti-anxiety medication.
A study found that people whose fathers began smoking at age 15 or younger show signs of faster biological aging compared to chronological age. This accelerated aging is linked to a higher risk of diseases such as cancer, arthritis, and dementia. The researchers call for stronger efforts to prevent tobacco use in teenagers.
A multi-national study found that higher levels of air pollution are linked to worse symptoms of obstructive sleep apnea (OSA) in European patients. The study revealed a modest but measurable increase in the apnoea hypopnea index (AHI) for every one unit increase in PM10 concentration.
In a first-of-its-kind study, researchers found that unplanned, premature births outside hospitals in Austria posed significant challenges for emergency teams. The study identified key findings on how to improve outcomes for mothers and newborns, including the importance of standardised protocols, training, and equipment availability.
Researchers have quantified the costs of e-scooter injuries for the first time in Ireland, revealing an average cost of €1,726 per patient. The study found that e-scooter injuries mainly resulted in musculoskeletal injuries requiring major surgery, resulting in significant financial burdens on healthcare services.
A new PSMA-targeting radioligand therapy added to stereotactic body radiotherapy (SBRT) more than doubled progression-free survival in men with recurrent prostate cancer, delaying the start of hormone therapy by up to 24 months. The study found minimal side effects and identified biological markers that may predict treatment benefits.
A new clinical trial found that patients with mild-to-moderate knee osteoarthritis reported significant reductions in pain and improved physical function after receiving low-dose radiation therapy. The study showed a 70% response rate in the high-dose group, compared to 42% in the placebo group.
A new randomized study validates a predictive gene expression test that identifies patients with recurrent prostate cancer who will benefit from adding hormone therapy to radiation. The test, PAM50, groups tumors into molecular subtypes and predicts treatment outcomes.
A new clinical trial found that adding a PSMA-targeting agent to stereotactic radiation therapy doubled progression-free survival in patients with limited metastatic prostate cancer. The study also showed that the treatment delayed hormone therapy by 24 months and improved local control.
Research shows that remote monitoring of children's asthma can prevent hospitalizations by around 57%. The system helps keep symptoms under control, leading to better outcomes and lasting self-management skills. This innovative approach could revolutionize healthcare services for patients with asthma.
A gold-standard randomised-controlled trial found that specialised singing programmes can improve the symptoms and quality of life of people with lung disease, particularly those with chronic breathlessness. The SINFONIA study showed a significant improvement in quality of life for patients with COPD and ILD.
A recent trial found that a combination inhaler reduced asthma attacks in children aged 5-15 by an average of 45% compared to salbutamol. The study also confirmed the safety of the combined-inhaler approach, with no significant differences in growth or lung function between groups.