Articles tagged with Molecular Recognition
Scientists systematically map the Biginelli reaction to uncover a previously unknown branch that produces complex bicyclic structures and molecules with unusual supramolecular behavior
Scientists at The University of Osaka developed a polymeric adhesive that can be reused repeatedly by introducing reversible bonds into the interface. This technology could improve manufacturing yield, reduce costs and minimize waste.
Researchers used NMR spectroscopy to capture enzyme dynamics, discovering a 'crossover loop' structure that plays a crucial role in catalyzing reactions. This new method promises unprecedented access to biomolecule mechanisms and potential pathologies.
UCSF scientists identified a receptor that enables microglia to engulf and digest amyloid beta plaques, leading to fewer and smaller clumps. This discovery creates an opportunity for new therapies targeting the receptor ADGRG1.
Researchers discover Dscamb protein regulates spacing between color-detecting cells, ensuring perfect arrangement for optimal vision. The protein acts as a 'self-avoidance enforcer' to maintain proper distances between cone cells.
Kayunta Johnson-Winters, a UTA associate professor of chemistry and biochemistry, has been honored as an American Society for Biochemistry and Molecular Biology fellow. Her research on F420-dependent enzymes has expanded understanding of disease proteins and paved the way for potential treatments.
Dr. Yonatan Stelzer has made significant contributions to understanding epigenetic mechanisms and embryonic development, challenging conventional knowledge with innovative approaches. His research aims to establish fully data-driven quantitative models of spatiotemporal processes in mammals.
Researchers at UCSF have discovered how a unique type of virus called a jumbo phage protects itself inside bacteria. The shield works via a set of secret handshakes that allow only useful proteins to pass through, giving the phage an advantage over regular phages when fighting infections.
Daniel Armstrong, a renowned UTA chemist, has been honored with the prestigious 2025 Pittcon Analytical Chemistry Award for his pioneering work in analytical chemistry. His research focuses on developing new approaches to identify chiral disease biomarkers, peptide epimers, and isotopic compounds.
A POSTECH research team found that EGF/EGF-like domains interact with GlcNAc-based biopolymers to achieve strong underwater adhesion without oxidation, leading to durable and reversible bonds.
Researchers explore the role of efferocytosis in reducing inflammation and containing injury spread after an ischemic stroke. Efferocytosis may offer a promising therapeutic strategy to promote neural regeneration and minimize brain damage.
Researchers developed a novel cyclic molecule that selectively traps phosphate species through multi-point hydrogen bonding in harmony with water molecules. The findings provide guidelines to design new cyclic molecules for aqueous environments, significant for materials development.
Two Hebrew University researchers have been selected to join the EMBO Young Investigator Programme, a prestigious initiative recognizing exceptional early-career group leaders in life sciences. The recipients will receive funding and training to foster scientific excellence and interdisciplinary collaboration.
Dr Bøsch's work explores betalains' potential to impact blood pressure, diabetes, cardiovascular health, and gut microbiota. The award highlights the significance of her research in advancing functional food and feed applications with implications for human and animal health.
Julian West, assistant professor of chemistry at Rice, recognized for harnessing free radical intermediates through inner sphere photocatalysis. His work holds significant implications for organic synthesis and developing next-generation therapeutics and materials.
Scientists at UMC Utrecht developed a new technology to isolate and study gut bacteria recognized by IgA antibodies, which are associated with various diseases. The next-generation IgA-SEQ method allows for high-throughput identification and analysis of these immunostimulatory bacteria, shedding light on their role in health and disease.
Researchers at University of California - San Francisco designed biological sensors that can ensure engineered cells are activated in tumor environments, making cancer therapies more effective. The new sensors, called SNIPRs, can bind to soluble molecules and alter gene expression, offering a promising approach for targeted therapies.
The new nanodevice shows significant efficacy against pathogenic microorganisms such as Escherichia coli, Staphylococcus aureus, and Candida albicans. It improves the efficacy of encapsulated cinnamaldehyde by up to 52-fold for E. coli and 60-fold for S. aureus.
The team developed a 'catch-and-release' mechanism to oxidize hydrophobic compounds, selectively and efficiently producing hydrophilic products under mild conditions. This breakthrough enables the selective two-electron oxidation of anthracene and aromatic compounds from mixtures, solving a long-standing challenge.
Researchers at Northwestern University have developed an electron-based catalyst for noncovalent bonding, promoting self-assembly and complex structure formation. This breakthrough enables the control of molecular recognition processes at a fundamental level.
A research team led by Professor Wonyoung Choe has developed a new paradigm for designing future structures of metal-organic polyhedra (MOPs). They found that multiple weaker bonds can play a similar role to strong bonds in constructing predictable structures.
Researchers have successfully integrated the shape-shifting molecule bullvalene into a coordination cage, restricting its fluctuating behavior and enabling controlled molecular recognition. This breakthrough could lead to the development of responsive materials with fast adaptation capabilities.
Researchers developed single-cell yolk-shell capsules with high biological activity and stability, addressing limitations in industrial reactors. The capsules exhibit size-dependent permeability and molecular recognition abilities, enabling enhanced cell survival and viability.
Researchers at Virginia Tech are developing novel polymers that incorporate DNA base pairs, resulting in enhanced elasticity and self-healing capabilities. These biobased materials have potential applications in various industries, including automotive and biomedical sectors.