Articles tagged with Molecular Structure
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Berkeley Lab researchers generate 3-D images of 129 DNA structures, revealing the dynamics and flexibility of DNA origami particles. The method used provides a new strategy for improving control over large DNA scaffolds by redesigning DNA sequences near joints to stiffen the structure.
Researchers developed a printing technique combining molecular self-assembly with additive manufacturing to create complex biological structures. This allows for the study of biological scenarios such as cancer growth and immune cell interactions, potentially leading to new drug development.
Researchers propose a new method to solve the complex many-particle Schrödinger equation, enabling accurate electronic energies and advancing fields like drug discovery and nuclear physics. The approach merges deterministic and stochastic methods to identify key wave function components.
A new study develops an innovative simulation model to predict the three-dimensional conformation of ribonucleic acid molecules, overcoming limitations of existing models. The model shows promising results in predicting RNA structures, with potential implications for basic research and medical therapies.
Researchers have accurately determined the molecular structure of alpha-pinene in its gas phase. This breakthrough analysis can help scientists better detect and understand how alpha-pinene reacts with other gases in the atmosphere, producing pollutants and particles that affect health and climate.
Researchers at Van Andel Research Institute have determined the atomic-level structure of TRPM4, a protein responsible for regulating blood flow to the brain. The 'crown-like' structure reveals new facets of its makeup and provides a molecular blueprint for designing effective medications with fewer side effects.
The German Research Foundation will fund TRR 83 for a further four years to study biological membranes and their functions. Biological membranes with proteins and lipids mediate various functions, from barriers to signal transduction platforms.
Researchers discovered two primary forces at play: hydrogen bonds and phase segregation, which strengthen or weaken each other. The study improves understanding of polymer structure formation, enhancing knowledge about self-healing materials and protein structures.
The Donald Danforth Plant Science Center has received a $3.4 million grant from the National Science Foundation to develop novel methods for predicting a plant's phenotype and precisely manipulating plant architecture traits in maize. The project aims to enhance yield potential and address the plateaued yields in recent years.
Researchers from RUDN University refined understanding of synthetic toxin causing mutations in lionfish embryos. Using X-ray diffraction and NMR analysis, they determined the molecule's spatial structure, contradicting earlier interpretation.
Researchers at RUDN University developed a new complex mercuric compound with unusual structure using non-covalent interactions. The compound can be used to create molecular machines, which are molecules capable of mechanical work.
Researchers used microwave spectroscopy to analyze the structure of a single molecular motor, revealing its stator, rotor, and axle. The study provides insight into the motor's dynamics and opens up possibilities for studying nano-machines in action.
Researchers at Trinity College Dublin have developed 'molecular cages' that can boost reactivity and storage capacity, offering promise for energy conversion and bio-sensing applications. The new material's enormous internal surface area makes it ideal for encapsulating molecules with specific functions.
A team of researchers led by Carnegie Mellon University chemist Roberto R. Gil and Universidade Federal de Pernambuco chemist Armando Navarro-Vázquez has developed a program that automates the process of figuring out a molecule's three-dimensional structure, reducing human error and shortening the pipeline of drug discovery.
Scientists at the University of Vienna created a hybrid carbon system with graphene sheets enclosing fullerenes. This setup allows for the observation of fullerene diffusion and rotation within the graphene sandwich, providing new insights into molecular dynamics.
A 10-year Lassa virus research project has yielded structural and functional details of a key viral surface protein, which could help advance development of Lassa vaccines. The study provides the first detailed view of the Lassa glycoprotein precursor complex bound to a human neutralizing antibody.
Researchers at Kanazawa University have developed a compound that selectively captures n-alkane gas molecules with its color change, indicating a special ability to distinguish configuration of guest molecules. The compound's properties were evaluated in solid/gas interfaces, showing excellent separation efficiency and recyclability.
Researchers at the University of Basel and Paul Scherrer Institute have produced a wafer-thin ferrimagnet by arranging phthalocyanine molecules on a gold surface in a checkerboard pattern. The material exhibits two-dimensional magnetic properties, making it suitable for applications such as sensors and quantum computing.
Chemists at Ruhr-University Bochum developed a new terahertz calorimetry technique to map changes in water molecules around solutes. This method allows for real-time analysis of hydration shells and can be applied to complex systems like enzymes for drug design.
Researchers at OIST created self-assembling molecules that can be rearranged by ultraviolet light to form novel macroscopic structures. This breakthrough enables the creation of exotic nanostructures with tailored functions, holding potential for biological and pharmaceutical applications.
Researchers at FAU have successfully assembled and tested conductors and networks made of individual molecules. The 'Lego bricks' can fabricate the smallest nanostructures under precision-controlled conditions, opening up possibilities for optoelectronic applications.
Researchers at Sandia National Laboratories have made a breakthrough in converting lignin, plant waste from biofuel production, into useful products like renewable plastics and fabrics. The discovery of LigM enzyme has opened a path toward new molecules and marketable products, potentially making biofuels competitive with petroleum.
Researchers at Northwestern University developed a new method, GAMERS, to extract the static and dynamic structure of complex chemical systems. This four-dimensional coherent spectroscopic method reveals hidden features of molecular structure, enabling insights into quantum phenomena and potential applications in solar cells.
Researchers found that modifying molecule structure can influence crystallization path, leading to better control over materials assembly. The discovery may lead to improved design of pharmaceuticals, energy technologies, and food products.
Researchers capture snapshots of electronic structure during a transient state of a reaction using femtosecond pulses of X-ray light on a tabletop apparatus. The study provides insights into the ring-opening reactions of cyclic molecules, relevant to photobiological synthesis and optoelectronic technologies.
Researchers at Kyoto University discovered that nanocages facilitate the fast folding and stability of G-quadruplexes, a type of biomolecule. This breakthrough has potential applications in understanding diseases, cancers, and allergies, as well as developing new drug treatments.
Berkeley Lab researchers develop first 3-D atomic-scale model of P22 virus that identifies critical protein interactions crucial for its stability. The successful rendering allows peeking inside the virus' protein coats at resolution.
Researchers at Dartmouth College have developed a 3D printing method to transform microscopic nanorings into smart materials that perform work at human-scale. The new technique enables the creation of complex smart devices beyond current grasp, with potential applications in soft robots and other tasks.
Researchers at Forschungszentrum Jülich develop a method to mix molecules with opposing intermolecular interactions, creating tailored surface structures. The technique enables the controlled production of active layer systems, which are crucial for organic electronics applications.
The LOH-Theory suggests that amino-acids and primitive organisms arose in semi-liquid water systems saturated with functional organic substances, allowing for exothermal and thermodynamically feasible syntheses. The theory is supported by analyses of available literature and paleontological data on the origins of life on Earth.
Researchers developed predictive models that accurately anticipate the smell of molecules based on just a handful of features, outperforming traditional methods. The DREAM Olfaction Prediction Challenge demonstrated the potential for crowdsourced competition to advance our understanding of scent perception.
Researchers design a pod-like casing with liquid-crystal elastomers and molecular switches, demonstrating the ability to produce powerful movement at the molecular level. The device uses light-triggered re-arrangement of molecular switches to drive twisting helices in opposing directions, resulting in the bursting of the casing.
Researchers developed a computational method that allows for controlled fabrication of tiny electrical wires and other nanomaterials. By analyzing intermolecular interactions, the team was able to predict the outcome of molecular self-assembly with high accuracy, leading to potential breakthroughs in device manufacturing.
Scientists developed a generative neural network to create new pharmaceutical medicines with specific properties. The network, trained on millions of molecular structures, identified 69 potential anticancer compounds and hundreds more using a powerful extension of the method.
Researchers developed machine learning algorithms to reconstruct 3D protein structures using microscopic images, enabling faster discovery of new drugs for diseases like Alzheimer's and cancer. The approach eliminates prior knowledge requirements, making it possible to study previously inaccessible proteins.
Researchers at the University of Lincoln have determined the molecular structure of a new antibiotic, teixobactin, which holds promise in tackling drug-resistant bacteria. The discovery reveals that the antibiotic's disordered structure is essential for its biological activity, providing insight into how to produce effective derivatives.
A study by the UPV/EHU and University of Bologna has resolved a discrepancy in a biological system through accurate characterization using microwave spectroscopy. The research targets the 2-hydroxypyridine/2-pyridone model system, where different structures coexist under the same molecular formula.
Researchers at Johns Hopkins University successfully created DNA nanotube bridges that connected two molecular landmarks on the surface of a lab dish. This breakthrough could lead to the development of new medical devices and technologies that can communicate directly with cells, potentially revolutionizing the field of nanotechnology.
Researchers at Nagoya University have synthesized stable antiaromatic nickel norcorroles and investigated their interactions, revealing face-to-face interactions that form a triple-decker structure with aromatic characteristics. The resulting materials exhibit nonlinear optical properties and potential applications in optoelectronics.
Researchers study organizing principles behind high Z' crystal structures to understand material properties like solubility and bioavailability. By analyzing complex structures, they identify organization principles tied to chemical molecule details.
Scientists used cutting-edge imaging and computational tools to decipher the assembly process of ribosomes, revealing multiple routes for assembly and parallel pathways. This discovery has significant implications for understanding diseases and developing safer medicines.
Researchers have finally captured water molecules passing excess charges, revealing the Grotthuss mechanism. This process is crucial for understanding water's behavior in biological and industrial settings.
Researchers at MIT deciphered the structure of a long noncoding RNA and found that it interacts with a protein to control heart muscle cell development. The study reveals the importance of RNA structure in understanding its function, which could lead to new therapeutic approaches for cardiovascular disease.
A team of researchers has discovered the three-dimensional structure of infectious prions, revealing a four-rung β-solenoid architecture that allows for replication. This finding rules out existing theories and proposes a novel templating mechanism involving protein-protein interactions.
Researchers at Argonne National Laboratory capture atomic and electronic arrangements within a metalloporphyrin molecule using ultrafast X-rays. The study reveals an extremely short-lived transient state that lasts only a few hundred femtoseconds, which is crucial for the development of solar fuels.
Researchers have gained structural insights on a key protein from Aedes aegypti, the mosquito species most often linked to Zika. The study suggests compounds targeting this protein could kill mosquitoes and reduce cases of Zika and other illnesses.
Researchers at Berkeley Lab create a nanoscale display case to reveal new structural details for challenging molecules, including complex compounds and potential drugs. The new technique stabilizes molecules in sturdy structures, enabling precise X-ray views of their atomic structure.
Scientists at the University of Maryland School Medicine have elucidated details about synaptic transmission, a crucial aspect of brain function. They discovered an unexpected and precise pattern in neurotransmission using single-molecule imaging, revealing the core architectural structure of synapses.
A new study confirms the existence of polymorphs in nanomaterials, revealing two unique structures for gold nanocluster Au144(SR)60. This discovery opens up new avenues for designing nanoparticles with desired properties, paving the way for more efficient materials and applications.
Researchers used RNA simulations to understand how viruses fold into specific shapes, offering potential targets for treating retroviral diseases. The study's findings provide valuable information on the thermodynamic stability of RNA molecules and their behavior in different environments.
Researchers designed a helix-shaped supercrystal composed of quantum dots to separate organic molecules and enhance drug synthesis. The chirality of the supercrystal allows for accurate detection of chiral biomolecules, enabling precise identification of enantiomers in pharmaceuticals.
A team of chemists and physicists used atomic force microscopy to capture snapshots of molecules reacting on a catalyst's surface, revealing intermediate structures lasting for up to 20 minutes. This breakthrough expands the toolbox for designing new catalytic reactions and has implications for fields like materials science and medicine.
Researchers used a world-class camera to observe the atomic structure of proteins as they reacted to light in real-time. This breakthrough could lead to understanding how proteins function and ultimately inform treatment of diseases.
Researchers at JILA have developed a new technique using laser frequency comb spectroscopy to detect and identify large, complex molecules. The upgraded system cools molecules to near absolute zero, simplifying and strengthening absorption signals and greatly boosting the ability to identify the molecules.
Chemists develop methods to wind up molecules into screw-shaped structures using artificial molecules, demonstrating a mechanism to transfer handedness. The technique could be used to design molecules for catalysis or energy conversion.
Research reveals that fruit flies' adult and larval nervous systems share similar structures and molecular signatures, contradicting the traditional view of metamorphosis as two separate stages. The study uses lineage tracing to identify neuroblast lineages and discover unique neuroblasts controlling leg motor neurons.
Scientists at TUM have engineered ordered monolayers of molecular networks with photovoltaic responses, utilizing self-assembly on atomically flat, transparent substrates. The findings open up possibilities for the bottom-up fabrication of optoelectronic devices with molecular precision.
Scientists have made a breakthrough in understanding enzymes that break down tough biomass, crucial for producing biofuels from renewable sources. The discovery could lead to improved efficiency and environmental sustainability in industrial biofuel production.
Researchers develop a new technique to determine the spatial structures of proteins and molecules without prior knowledge, revolutionizing crystallography. The method provides insights into the modes of action of biomolecules and can lead to tailor-made drugs for diseases.
A team of researchers has revealed the molecular motions behind elastin's flexibility, showing how scissor-shaped molecules assemble into long chains that give tissues their stretchability. The study provides insights into the material's durability and could lead to new materials for engineering applications.