Articles tagged with Nucleobases
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
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Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
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Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers validated panels of antibodies targeting clinically relevant nucleic acid modifications to visualize antisense oligonucleotides in both in vitro and in vivo studies. The tools enable detection of modified nucleic acids irrespective of sequence, facilitating multiple clinical and pre-clinical workflows.
The OSIRIS-REx mission returned a large sample from asteroid Bennu, which Japanese collaborators detected includes all five nucleobases required for life. The analysis revealed high concentrations of ammonia and nitrogen-rich organic matter.
A team of researchers has discovered a wide range of nitriles, key molecular precursors for life, in the interstellar molecular cloud G+0.693-0.027 near the Milky Way center. The study provides important insights into the chemical ingredients available in the nebula that give rise to our planetary system.
Researchers at Georgia Institute of Technology discovered that RNA's chemical ancestors can spontaneously form spiral strands in plain water without catalysts or enzymes. The spiraling integrated another compound, forming a structure similar to RNA, and demonstrated the possibility of an early evolutionary path for RNA.
Scientists find that DNA and RNA have memory properties, with two stable states, making them suitable for storing data. The minimum electric field required for switching is inversely proportional to the ratio of topological polar surface area to total surface area.
A new study by Tohoku University researchers found that meteorite impacts can create nucleobases and amino acids, essential components of life. The team's hypervelocity impact experiments revealed the formation of two types of nucleobases and nine proteinogenic amino acids.
Scientists have discovered nucleobases, building blocks of genetic material, in meteorites that suggest an extraterrestrial origin. The findings, published in the Proceedings of the National Academy of Sciences, indicate that certain meteorites brought these compounds to Earth, providing a possible source for life.
Researchers have developed a new PNA molecule that can be used to construct nanodevices, thanks to its ability to form stable metal-containing duplexes even with non-complementary strands. This breakthrough could lead to the creation of novel electronic devices and materials.