Articles tagged with Nucleobases
Researchers validated panels of antibodies targeting clinically relevant nucleic acid modifications to visualize antisense oligonucleotides in both in vitro and in vivo studies. The tools enable detection of modified nucleic acids irrespective of sequence, facilitating multiple clinical and pre-clinical workflows.
The OSIRIS-REx mission returned a large sample from asteroid Bennu, which Japanese collaborators detected includes all five nucleobases required for life. The analysis revealed high concentrations of ammonia and nitrogen-rich organic matter.
A team of researchers has discovered a wide range of nitriles, key molecular precursors for life, in the interstellar molecular cloud G+0.693-0.027 near the Milky Way center. The study provides important insights into the chemical ingredients available in the nebula that give rise to our planetary system.
Researchers at Georgia Institute of Technology discovered that RNA's chemical ancestors can spontaneously form spiral strands in plain water without catalysts or enzymes. The spiraling integrated another compound, forming a structure similar to RNA, and demonstrated the possibility of an early evolutionary path for RNA.
Scientists find that DNA and RNA have memory properties, with two stable states, making them suitable for storing data. The minimum electric field required for switching is inversely proportional to the ratio of topological polar surface area to total surface area.
A new study by Tohoku University researchers found that meteorite impacts can create nucleobases and amino acids, essential components of life. The team's hypervelocity impact experiments revealed the formation of two types of nucleobases and nine proteinogenic amino acids.
Scientists have discovered nucleobases, building blocks of genetic material, in meteorites that suggest an extraterrestrial origin. The findings, published in the Proceedings of the National Academy of Sciences, indicate that certain meteorites brought these compounds to Earth, providing a possible source for life.
Researchers have developed a new PNA molecule that can be used to construct nanodevices, thanks to its ability to form stable metal-containing duplexes even with non-complementary strands. This breakthrough could lead to the creation of novel electronic devices and materials.