Bluesky Facebook Reddit Email

Lab-grown retinas explain why people see colors dogs can’t

Researchers discovered how an offshoot of vitamin A generates the cells that enable people to see millions of colors. The study found that a molecule called retinoic acid determines whether a cone will specialize in sensing red or green light, making humans uniquely color-savvy.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

How ‘pioneers’ blaze the one trail that determines cell fate

Researchers have discovered how pioneer transcription factors, such as FOXA and OCT4, coordinate with epigenetic repressors to safeguard cell fate, enabling precise manipulation of cell fate in cellular programming and reprogramming. This breakthrough has important implications for scaling up organoid and tissue engineering technology.

Novel tissue-derived brain organoids could revolutionize brain research

Scientists have developed mini-brains from human fetal brain tissue that self-organize in vitro. These lab-grown organoids can study brain development and disease, including brain tumors. They offer a valuable means to untangle the complex network of molecules involved in directing brain development.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Exploring the effects of vascularization strategies on brain organoids

A study by Waseda University explores the effects of different vascularization strategies on brain organoids, improving cell differentiation and transcriptome profiles. Vascularized cerebral organoids exhibit a gene expression profile closer to fetal human brains than non-vascularized ones.

Potential new treatment for pulmonary neuroendocrine tumors

Researchers have developed a new model for studying pulmonary neuroendocrine tumors, which may indicate that patients with EGF-dependent NETs can be treated with EGF receptor inhibitors. This discovery provides a promising route of treatment for aggressive pulmonary NETs.

Unlocking the secrets of the brain’s dopaminergic system

A new organoid model replicates the dopaminergic system's structure, connectivity, and functionality, shedding light on its intricate functionality and potential implications for Parkinson’s disease. The model also uncovers the enduring effects of chronic cocaine exposure on the dopaminergic circuit, even after withdrawal.

Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

New strategies generate more accurate pediatric brain organoids

Researchers at the Princess Máxima Center and Hubrecht Institute developed a new cortex organoid that more accurately captures essential features of the human brain. The mini-organs can be used to model pediatric brain tumors, offering potential targets for treatment.

Apple AirPods Pro (2nd Generation, USB-C)

Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

Miniature colons with immune components aid the study of intestinal diseases

Researchers at MUSC and Cincinnati Children's have developed a novel colon organoid model with naturally occurring immune cells. The model has the potential to improve treatment outcomes for colon-related diseases such as cancer and IBD by providing a more complete human organoid system that can be used to model inflammation in the colon.

Genetic switches in tumor development

Researchers at Kanazawa University found that genetic alterations underlie the dual function of activins in colorectal cancer. Mutations in genes such as Kras and Trp53 can promote tumor progression while also suppressing it, highlighting the complex role of TGF-ß signaling.

GoPro HERO13 Black

GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.

Controlling organoids with light

Scientists have developed a way to regulate gene expression in organoids using optogenetics, enabling the observation of cell behavior and development patterns. This breakthrough allows for more accurate reproduction of tissue processes in the petri dish.

Lab-grown skin helps unlock secrets of mpox virus infection

Researchers have developed a lab-grown human skin model that effectively replicates mpox virus infections, providing insights into the virus's mechanisms of attack on skin cells. The study reveals how the virus causes disease and identifies potential therapeutic targets, including an antiviral drug called tecovirimat.

Human vascular organoids reveal clues for a potential COVID treatment

Researchers have developed a human vascular organoid model that accurately mimics the damage caused by SARS-CoV-2, revealing clues for a potential COVID-19 treatment. The study identified a long-acting monoclonal antibody targeting factor D as a promising approach to mitigate severe vascular damage and thrombosis associated with COVID-19.

GQ GMC-500Plus Geiger Counter

GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

CHOOSEn fate: one brain organoid’s tale on Autism

Researchers developed a technique called CHOOSE that allows them to test the effect of multiple mutations in parallel and at a single-cell level within human brain organoids. The study identified critical transcriptional changes regulated through common networks, or GRNs, and found that some cell types are more susceptible to autism mu...

Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Revolutionizing recovery after a heart attack

A preclinical study suggests that nanowired cardiac organoids could repair hearts instead of just preventing further damage. The treatment, led by Dr. Mei and Ryan Barrs, showed a 69% increase in heart function, promising a new therapy for heart disease.

Application of base editors in organoids opens new doors for cancer research

Researchers used base editors to introduce specific combinations of activating and inactivating mutations into healthy organoids, creating realistic models for various types of cancer. This allows for further investigation into the development and treatment of cancer, with potential applications including testing new drugs.

Stem-cell derived organoids secrete tooth enamel proteins

Researchers successfully created stem-cell derived organoids from human stem cells that secrete three essential enamel proteins. These proteins form a matrix that undergoes mineralization to create a hardened enamel structure. The breakthrough offers hope for developing novel treatments to repair and regenerate teeth.

Synthetic extracellular matrix supports endometrial organoids

Scientists have developed a synthetic extracellular matrix that can support the growth of mini endometria in a dish for at least two weeks. This allows researchers to study its role in healthy and diseased states, such as endometriosis, by extrapolating from patient samples.

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Organoids revolutionize research on respiratory infections

Researchers developed AirGels, bioengineered models of human lung tissue, to study airway infections in a more realistic manner. They found that Pseudomonas aeruginosa induces contraction of the host's mucus using type IV pili, contributing to biofilm formation.

Understanding metabolites underlying eye development

A new Northwestern Medicine study has furthered the understanding of metabolic pathways underlying organ development, specifically eye development. The research found that aerobic glycolysis and production of lactate regulate critical genes required for early eye development.

AmScope B120C-5M Compound Microscope

AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

Studying herpes encephalitis with mini-brains

Researchers at Max Delbrück Center developed a new model of the brain using human stem cells, which showed promise in treating HSV-1 induced encephalitis. By combining an anti-viral with an anti-inflammatory drug, they were able to prevent tissue damage and promote recovery.

Davis Instruments Vantage Pro2 Weather Station

Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

3D 'bio-printing' inside hydrogels

Researchers achieve 3D printing within mini-organs growing in hydrogels, allowing for precise control over shape, activity, and tissue growth. This breakthrough enables the creation of realistic models of organs and disease, with potential applications in cancer research and treatment.

Purified pituitary tissue generated from stem cells

Scientists have successfully converted human pluripotent stem cells into purified pituitary cells that secrete adrenocorticotropic hormone (ACTH), a hormone normally produced by the pituitary gland. Transplantation of these cells into mice with hypopituitarism resulted in long-lasting improvement in ACTH levels.

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

Lab-grown mini lungs could accelerate the study of respiratory diseases

Researchers have developed a technology to grow genetically identical mini lungs on microchips, enabling high-throughput analysis of lung tissue infections and identification of candidate therapeutics. The platform can track thousands of lung buds at once, revolutionizing the study of respiratory diseases like COVID-19.

Scientists target human stomach cells for diabetes therapy

Researchers at Weill Cornell Medicine have successfully converted human stomach stem cells into insulin-secreting cells, offering a promising approach to treating type 1 and severe type 2 diabetes. The transplants reversed disease signs in mouse models, suggesting good durability.

Brain research with organoids

Scientists have developed a new method to genetically modify brain organoids, allowing for quick and effective analysis of gene function in early stages of brain development. This breakthrough enables comparative studies across primate species and simulates neurological diseases without animal experiments.

DJI Air 3 (RC-N2)

DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

New way to model human brain immune cells

Researchers create a human-brain-like environment to study microglia development and function for the first time in living human-derived tissue. The findings suggest that brain environment influences microglia development and function, particularly in diseases such as autism spectrum disorder and Alzheimer's disease.

Detailed image of the human retina

Researchers have created a detailed map of human retinal organoid development, revealing information on cell types, proteins, and gene expression. The study uses advanced imaging techniques to visualize multiple proteins simultaneously and provides insights into retinal diseases such as retinitis pigmentosa.

Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

Organoids validated as tool for studying fetal intestine development

Cincinnati Children's scientists have successfully grown functional human intestinal organoids that mimic key development stages of the human fetus. These lab-grown tissues accurately replicate the formation of specific cell types and tissue structures, providing a valuable resource for studying fetal intestine development and potentia...

New insights into liver cancer using organoids

Researchers used human liver organoids to study fibrolamellar carcinoma, a rare childhood liver cancer. They found that different genetic mutations underlie different degrees of aggressiveness in the tumors, and uncovered the probable cell-of-origin as hepatocytes.

Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Organoids shown to speed glycoengineered vaccine development

Researchers have developed an organoid-based method to assess the potency of glycoconjugate vaccines, speeding up the vaccine development process. This method uses tissue from a single mouse to create hundreds of immune organoids, allowing for the assessment of dozens or even hundreds of vaccine candidates in just four days.

Simple but revolutionary modular organoids

Scientists at RIKEN have developed a new technique for creating complex 3D organoids using a cube-like structure made of hydrogels. This innovation enables researchers to control the environment around cells, allowing for the creation of tissues with faithful reproduction of asymmetric genetic expression. The technology has the potenti...

Tumor avatars to fight colorectal cancer

A UNIGE team created customizable treatments by testing drugs on artificial tumors derived from patients' cancer tissue. The approach opens the way for optimized and tailored therapies against various cancers and diseases.

Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Groundbreaking lymphoma tumor model paves way for new therapies

Researchers at Georgia Institute of Technology developed a synthetic tumor model to understand the impact of microenvironment on targeted therapies for Activated B Cell-like Diffuse Large B cell lymphoma. The model showed promise in demonstrating how combining therapeutics can overcome tumor resistance to inhibitors.