Articles tagged with Electron Microscopy
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers developed high-precision X-ray deformable mirrors for controllable beam size and formed three types of focused beams without changing experimental setups. This paves the way for a multifunctional X-ray microscope to perform various analyses in one device, enhancing flexibility and range of uses.
The MCU structure is a homopentamer with a hydrophilic pore, featuring two carboxylate rings as the ion selectivity filter. This novel ion channel architecture suggests a passage for calcium transport.
A proof-of-concept study demonstrates a new method using super-resolution microscopy can accurately diagnose rare platelet disorders, offering an alternative to costly and resource-intensive electron microscopy. This innovative approach provides personalized treatment options, saving the NHS money and improving patient outcomes.
Researchers from McMaster University successfully tracked individual catalyst nanoparticles during heating using advanced electron microscopy techniques. This breakthrough could lead to the development of less expensive catalysts, such as platinum-iron nanoparticles, reducing dependence on imported oil and greenhouse gas emissions.
Researchers have unlocked the structure of a plant virus using groundbreaking microscopy, revealing key to building custom virus-like particles that can carry medicines into the human body. The findings could lead to the development of targeted medicines.
Researchers at RIKEN Brain Science Institute developed a new optical clearing technique called Sca l eS, enabling the creation of transparent brain samples for detailed analysis. The technique has provided new insights into Alzheimer's disease pathology and revealed associations between amyloid beta plaques and microglial cells.
Researchers at the University of Leeds captured images of motor protein dynein in action using electron microscopes. The study revealed a hinge between the motor's arms and its track, allowing flexibility in movement.
Rice University researchers have developed a new technique to characterize the space within porous materials, allowing them to measure dimensions and dynamics at the nanoscale. This breakthrough could improve protein separation processes for the pharmaceutical industry.
Scientists have finally understood the structure of a flexible plant virus that has resisted description for over 75 years, revolutionizing efforts to stop such viruses and potentially leading to new vaccine delivery methods.
EPFL scientists have developed a new method called cryofixation to preserve the brain's true structure, overcoming distortion caused by traditional fixation methods. This breakthrough allows for unprecedented detail in brain imaging and has significant implications for understanding brain anatomy and function.
Ze'ev Reches and collaborators study earthquake instability and fault weakening mechanisms using electron microscopy. They find phase transformation and nano-size grains are associated with profound weakening, resolving two major conflicts in laboratory results and natural faulting.
Researchers developed a hybrid approach combining core-loss spectroscopy and ultrafast four-dimensional electron microscopy to visualize structural dynamics of atomic-scale materials. The technique revealed tiny electronic changes in individual atoms within a material on ultrafast time scales.
Scientists found small square crystals of ice at room temperature in a transparent nanoscale capillary made from graphene, which allowed them to see individual water molecules. The researchers used computer simulations to find that thin layers of water can form square ice independently of the material's chemical makeup.
UC Davis researchers use new techniques in electron microscopy to study HIV and other viruses. They find that the gp120 trimer associates with gp41 to form a structure that allows HIV to enter host cells. The study also reveals how viruses hijack cellular processes to enter cells, shedding light on potential vaccine targets.
Researchers have successfully observed atomic positions and electron distribution during the transformation of vanadium dioxide from a semiconductor to a metal. This achievement marks the first time that experiments can distinguish between atomic-lattice structure changes and electron relocation at ultrafast speeds.
Scientists discovered a new material, WTe2, exhibiting unlimited growth in magnetoresistance when exposed to strong magnetic fields. This phenomenon could be useful for detecting magnetic fields in scanners.
Researchers have successfully imaged gold nanoparticles at atomic resolution using high-resolution electron microscopy, revealing a crystalline structure with 68 gold atoms. The breakthrough opens the way for understanding and practical applications of nanoparticle structures.
Biologists at MTSU have optimized FIB-SEM technology to image plant cell architecture, revealing previously unseen aspects of organelle organization and function. The technology provides high-resolution images of plant cells, allowing researchers to explore new questions and expand their understanding of plant development.
A team of scientists has visualized the desorption of oxygen molecules from a silver surface using low-energy electron microscopy. They found that the process involves isolated islands breaking up on the surface, leading to discrepancies between theoretical predictions and experimental measurements.
Researchers at the University of Illinois Chicago have developed a graphene 'sandwich' that enables atomic-level imaging of biomolecules in their natural state. This breakthrough improves resolution and minimizes damage to samples, opening up analysis of difficult-to-image biological samples.
Researchers at Caltech used high-resolution electron microscopy to visualize HIV infection in the gut of an infected mouse model. The study revealed novel observations about HIV behavior, including semisynchronous wave patterns of virus release from infected cells and transmission through free pools of virus.
A new microscope allows scientists to capture the movements of atoms and molecules at the nanoscale, revealing crucial functions in nanoscale devices. This breakthrough has applications in nanoelectronic technologies and clean-energy industries.
Scientists at Rice University have created a method to locate specific sequences along single strands of DNA, which could help diagnose genetic diseases. The 'motion blur point accumulation' technique resolves structures as small as 30 nanometers by capturing images of fluorescent probes binding to target DNA.
Researchers used a new electron microscopy method to study high-pressure samples of carbon, detecting unexpected atom types and locations within minerals. The findings explain how large amounts of carbon reside in the Earth's interior, addressing a long-standing problem.
Researchers create a method to convert conventional microscopes into high-resolution imaging systems that outperform standard microscopes. The new system combines the field-of-view advantage of a 2X lens with the resolution advantage of a 20X lens, producing images with 100 times more information.
Researchers at EMBL used super-resolution microscopy to determine the arrangement of Y-shaped molecules in the nuclear pore complex, resolving a decade-old controversy. The study found that the Ys lie in an orderly circle around the opening, with all arms pointing towards the centre.
Researchers develop a platinum-nickel nano-octahedra material that accelerates hydrogen and oxygen conversion to water, saving 90% of typical platinum usage. The unique atomic structure enhances reactivity while limiting lifetime.
Biologist Luis Vidali will explore how components of a cell's internal anatomy organize themselves to grow in a single direction, critical for vital functions in animals, plants, and fungi. He will use genetic techniques, advanced microscopy, and computer simulations to compile a complete picture of the mechanisms involved.
A $4 million international collaboration aims to create a noninvasive quantum electron microscope, enabling real-time imaging of living cells at molecular resolution without radiation damage. The project has the potential to revolutionize our understanding of biology and fundamental physics.
Researchers at Berkeley Lab's Advanced Light Source are transforming X-ray microscopy into a widely available form of high-resolution imaging. State-of-the-art instruments can create three-dimensional images with elemental and/or chemical sensitivity, allowing for unprecedented insights into biological systems.
Scientists at Caltech have developed a unique microscope that captures the motion of DNA structures in both space and time, allowing them to directly measure stiffness and map its variation. This breakthrough technique has far-reaching implications for understanding biological nanomaterials and their properties.
Researchers at TUM and PSI have developed a method to visualize material fluctuations and nanostructures using X-ray microscopy. This technique relaxes the hard restrictions of immobility required for high-quality imaging, enabling the visualization of previously inaccessible objects.
Researchers share code for Amazon Cloud that significantly reduces time necessary to process super-resolution images, enabling biologists to study molecular machines like proteins and enzymes in greater detail. The method saves over a week's worth of time, making it possible to analyze data within hours instead of days.
Researchers at TSRI have determined the structure of Ltn1, a 'quality-control' protein that ensures protein-making machinery works smoothly. The study suggests Ltn1 may be relevant to human neurodegenerative diseases such as ALS.
Researchers developed a new nanotech tool to probe solar-energy conversion, revealing exquisite chemical details with a resolution thought impossible. The tool combines scan/probe microscopy and optical spectroscopy, enabling scientists to examine nanoscale chemistry and interactions with light.
Researchers from MIT have developed a new tag, APEX, that enables high-resolution visualization of proteins in cells using electron microscopy. The APEX tag allows scientists to label and identify specific proteins with unprecedented clarity, resolving open questions regarding protein locations and functions.
Cold atmospheric gas plasma technology has shown promise in inactivating Salmonella on fresh produce, but exposure length varies greatly depending on the type of produce. Researchers discovered that food surfaces' microscopic structures can block plasma from reaching bacteria, affecting treatment efficacy.
Researchers can now navigate biological tissues from whole embryo to subcellular structures thanks to virtual nanoscopy and enhanced JCB DataViewer. The technique allows for exceptional opportunities for future discoveries by integrating information across cells and tissues.
Researchers at EMBL develop method to follow molecules under light and electron microscope, revealing crucial protein interactions in endocytosis process. They discover actin scaffolding protein forms network pulling membrane inwards.
Scientists at the University of Illinois have developed new microscopy techniques to analyze pollen grains, enabling better classification of prehistoric flora. The research highlights the importance of pollen morphology in understanding the evolution and diversity of ancient vegetation.
Berkeley Lab scientists create thinnest possible films of gold-silicon eutectic alloys and observe peculiar patterns of circles surrounded by blisters. The team finds that thinner gold layers lead to faster reaction rates and the formation of perfect squares in the center of the circular denuded zones.
The University of York team has developed electron beams with orbital angular momentum, enabling the efficient examination of magnetic materials. This breakthrough promises novel applications in nanoparticle manipulation and edge contrast detection.
Scientists have developed a new technique that allows them to create detailed 3D images of individual proteins using cryo-electron microscopy. This breakthrough enables researchers to study the flexibility and movement of proteins, which is crucial for understanding their function and developing new drugs.
University of Alberta researchers create a miniature model of oil-trapping rock layers using core samples from drilling sites. The 'reservoir on a chip' model helps energy companies determine optimal water and chemical concentrations for maximum oil recovery.
A new electron microscopy method resolves the structure of tiny crystals, opening up a door to nanostructures. The method is faster and more accurate than conventional methods, allowing for detailed analysis of materials like zeolites and minerals.
The study reveals that neurons normalize receiving signals by adjusting their morphological characteristics, making it easier to receive farther signals. The research team's 3D image reconstruction of minute dendritic tree morphology demonstrates the size and distance of dendritic trees determine signal clarity and strength.
UCSD scientists create a new type of genetic tag visible under an electron microscope, allowing for detailed, three-dimensional images of individual cells. The modified protein, dubbed miniSOG, produces abundant singlet oxygen when exposed to blue light, enabling its visualization.
Scientists at UCSD and colleagues create a new type of genetic tag visible under electron microscopy, enabling detailed three-dimensional images of individual cells. The breakthrough enhances electron microscopy capabilities, allowing researchers to visualize proteins in unprecedented detail.
Scientists at NIST have developed a method to measure the wear and degradation of AFM tips in real time, allowing for dramatic improvements in precision and speed. This technique uses contact resonance force microscopy to track the resonant frequency of the sensor tip, enabling atomic-scale resolution and reducing inaccuracies.
Researchers have created a carbon cloak made of graphene that protects bacterial cells from shrinking under electron microscopes, allowing for high-resolution imaging. The graphene cloak uses the material's impermeability and strength to retain water in the cells, enabling scientists to observe them at their natural size.
A team of researchers at Harvard Medical School has developed a technique to unravel the complex neural circuits in the brain. By crawling through individual connections, they created a partial wiring diagram that revealed interesting insights into how the brain functions.
Researchers at the National Institute for Nanotechnology have created the world's sharpest man-made object, a tungsten microscope tip with a diameter of just one atom. The breakthrough was achieved using a patented controlled etching method and has potential commercial applications.
Scientists have developed a microscope that can see objects as small as 50 nanometres, beyond the theoretical limit of optical microscopy. This breakthrough enables potential examination of human cells and live viruses for the first time, revolutionizing cell study and biomedicine.
Researchers Marta Rossell and Rolf Erni developed a new technique to study the 3D structure of nanoparticles, enabling the determination of their atomic arrangement. This breakthrough could improve understanding of nanoparticle properties, reactivity, and toxicity.
The team aims to create images revealing micro- and macroscopic matter with improved clarity, surpassing traditional microscopy resolution by 10-fold. This enables scientists to study living tissue in its natural state without sample manipulation.
Researchers have developed a new X-ray microscope that delivers immediate 3D images of entire living cells, closing the gap between conventional microscopic techniques. The new method allows for high-resolution imaging without chemical fixation or labelling, enabling detailed study of cellular ultrastructure.
A Scripps Research team has successfully imaged the formation of cells' protein factories using a novel technique. The breakthrough could lead to new antibiotic development and treatments for diseases tied to ribosome errors. The study offers insights into cellular processes and may uncover new targets for therapeutic interventions.
Scientists at EMBL discovered that a molecular signal triggers cell shape change necessary for zebrafish lateral line development. This change in shape allows cells to migrate properly along the embryo's sides, forming a rosette structure.
Researchers have successfully imaged the internal tissues of a soft-bodied marine worm using micro-computed x-ray tomography (micro-CT) without dissection or destructive methods. This technique allows for high-definition images and three-dimensional rotating views, enabling detailed study of functional anatomy.
Researchers used electron microscopy to observe Xylella fastidiosa bacteria breaking down plant cell walls, weakening and killing grape plants. The study aims to understand the disease's progression and develop prevention strategies.