Articles tagged with Animal Research
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
New research finds ancient oil droplets containing biomarkers from eukaryotes and cyanobacteria that lived before the planet's glaciation, contradicting previous theories. The study suggests oxygen was produced long before the atmosphere became oxygenated, supporting life in extreme conditions.
Researchers develop IMPY tracer to visualize abnormal protein in Alzheimer's and prion diseases, providing new directions for future research. The tracer may also aid in early diagnosis of Alzheimer's with single photon emission computed tomography (SPECT) imaging.
New findings of myglobin levels in the common carp could help scientists understand how humans could survive loss of oxygen supply to their tissues during a stroke or heart attack. The research suggests that the protein plays other roles in protection from low levels of oxygen, apart from storing oxygen.
Researchers found that withdrawal contributes to compulsive drug consumption in addicts, creating a vicious cycle. A previously unknown source of drug craving was also identified through Pavlovian conditioning.
Researchers found that Nepali rhesus macaques are genetically similar to Indian-origin animals, which could provide a new alternative for HIV/AIDS research. The study suggests that these animals may be representative of Nepali rhesus macaques in general, and their use in research could help address conservation concerns.
Researchers found that over 40% of the marshes have been reflooded and native species are recovering, with growth in giant reeds and rare bird sightings reported. However, challenges remain, including water supply issues and potential environmental threats from oil exploration.
Researchers Harry Roberts and Bob Carney are studying the animals that live near oil and gas seeps in the Gulf, including bacteria that feed on hydrogen sulfide gas. They will use the Alvin submersible to take them down to the bottom of the Gulf, where they hope to discover new species and learn more about these unique communities.
Researchers tracked sperm whales using acoustic recording tags, finding that they produced 'buzzes' to locate cephalopods like squid during deep dives. This non-invasive method provides insight into the timing of prey detection and capture during dives.
Researchers found that a slight difference in protein shape allows dioxin to bind more easily, triggering harmful effects. A test using molecular analysis could help assess dioxin sensitivity in wild animal populations.
The studies reveal that integrated treatments benefit patients with multiple psychological problems and that cooperation between judiciary and addiction care provides added benefits. Effective prevention programs are also available for young people, while animal experimental research offers perspectives on human addiction research.
A recent study compared how natural 'machines' and man-made technologies overcome similar problems, revealing that only 5% of natural machines rely on energy in the same way. Instead, insects, plants, birds, and mammals use the structure and organization of their body parts and behavior to solve problems.
Researchers find Hox system genes are independently evolved in cnidarians, contradicting its role as defining characteristic of metazoan animals. This discovery explains the remarkable morphological diversity seen in Cnidaria.
Researchers used Chlamydomonas reinhardtii to study cilia function and signaling in human cells. They found that intraflagellar transport (IFT) is necessary for cilia to bind with signaling molecules, enabling response.
Researchers discovered that males of the extinct species Thyrohyrax had oversized, swollen lower jaws shaped like a banana, which may have been used to produce sound. The discovery suggests that Thyrohyrax and its fossil relatives were the only mammals to use this skeletal structure for sound production.
Researchers at the University of Washington discovered a regulatory gene named broad that is necessary for insect metamorphosis. The study shows that the broad gene regulates the nymphal stage in lower insects, equivalent to the pupal stage of advanced insects like butterflies.
A new anthrax antitoxin has been designed using a fatty bubble studded with small proteins that can effectively neutralize the toxin. The polyvalent inhibitor showed 10,000 times more potency than unattached peptides and prevented five out of nine rats from becoming ill when given in combination with antibiotics.
A polyvalent inhibitor has been developed that recognizes multiple sites on the anthrax toxin molecular structure, making it four orders of magnitude more potent. The inhibitor was tested in rats and protected them from anthrax toxin, showing promise as a potential therapeutic for anthrax exposure.
Researchers at La Jolla Institute for Immunology have made a major finding on a potential cure for type 1 diabetes by combining two therapies, producing better efficacy and longer-lasting results in preclinical trials. The combination therapy is being planned to begin human clinical trials later this year.
Researchers found that animals can detect movement direction from foot cues, which may help avoid predators. This low-level locomotion detector is part of an evolutionary old system, suggesting animal brains are 'hard-wired' for this type of recognition.
A 10-year study of wild finches reveals that female birds choose mates based on genetic diversity, not flashy traits. This helps explain why elaborate ornaments evolve despite potential inbreeding risks.
The lizard's parietal eye photoreceptors contain two pigments, allowing it to respond to blue and green light in the same cell. This unique mechanism may have been an economical way to detect changes in sunlight during dawn and dusk. The study proposes a 'missing link' between the light-sensing apparatus of lower animals and humans.
A new gene, Lazaro, has been discovered to reduce retinal degeneration in fruit flies by enhancing the production of diacylglycerol, a key player in controlling TRP channels. This discovery may have implications for understanding sensory signaling in mammals.
Researchers discovered that African legless amphibian B. taitanus females provide nutrition to their hatchlings via their skin for up to four weeks. This post-hatching parental care is unprecedented in amphibians and may represent an evolutionary intermediate between reproductive modes.
Researchers found that worms dwelling at ocean depths of 2,200 meters prefer temperatures around 50 degrees Celsius, outperforming other species. This adaptation allows them to graze on bacterial lawns that no other organism can access, with some species succumbing to heat quickly.
A study of zoo lions across the US found that cold temperatures contribute significantly to mane length and density, with up to half of the variation attributed to temperature. The research suggests that lion manes may not be as genetically determined as previously thought.
Yale researchers found that environmental toxins like TBT can alter the balance of chloride ions in outer hair cells, causing profound changes in sound amplification in the inner ear. This study confirms that whales and other marine mammals exposed to TBT have altered hearing and may contribute to beaching incidents.
Researchers have made a breakthrough in understanding the role of AMPA receptors in strokes, with potential to prevent brain damage and improve learning and memory. By modifying one part of the genetic blueprint of these receptors, they aim to protect neurons from lethal calcium flows, which can cause irreversible brain damage.
The carp's extraordinary ability to adapt to low oxygen conditions allows it to thrive in environments where other fish would perish. Researchers have discovered that its blood has a higher affinity for oxygen than any other vertebrate, enabling the fish to maintain physical activity while oxygen supplies are limited.
Researchers administered stem cells to animals with significant mobility loss after stroke, showing a 25% greater improvement in motor function compared to controls. In another model of cerebral palsy, rodent stem cells improved recovery by at least 25% within two weeks.
Researchers found that cystamine and a related drug increase levels of protective protein HSJ1b, which helps neurons survive in Huntington disease. This may lead to potential treatments for the neurodegenerative disorder.
Paleontologist Josh Smith rediscovered two photographs of the holotype of Spinosaurus aegyptiacus, providing new insight into the dinosaur's skeleton. The images were found in the Palaontologische archives of the Museum in Germany and allow for direct comparison with Stromer's 1915 illustrations.
A new mouse model reveals that moderate alcohol consumption fuels blood vessel growth and encourages cancer tumors, increasing the risk of cancer. The study suggests that blocking VEGF over-production could reduce cancer incidence and provides a potential tool for cancer education and prevention.
Research found harbor seals that were heavier when captured continued to gain weight on high fat and low fat diets, but smaller pups lagged behind. The study suggests changes in prey availability, including herring, may contribute to the declining seal population.
Researchers found that elevating perceived sexual competition in male house mice led to increased vigorous thrusting and premature ejaculation during copulation. Males were nearly twice as likely to ejaculate on a second occasion when a rival male was present.
Brain scans of depressed female monkeys reveal lower serotonin receptor binding in all brain areas, supporting previous studies. The findings suggest that these animal models can help researchers understand depression and develop new treatments.
Native insects provide valuable services worth $50 billion in recreation industry, $4.5 billion in pest control, $3 billion in crop pollination, and conserving grazing lands valued at $380 million annually. Insects are crucial for human survival, and their ecological functions need to be conserved or enhanced through research investment.
Researchers have discovered a plant enzyme called Mir1-CP that protects corn from pests by degrading insects' peritrophic matrix. The enzyme accumulates at feeding sites within an hour of caterpillar feeding, causing impaired nutrient utilization and inhibiting growth.
Researchers have developed a new family of biodegradable polymers, called polyketals, that can deliver drugs to cells more efficiently and with reduced inflammation. These polymers degrade into FDA-approved compounds and generate membrane-permeable products that allow byproducts to diffuse outside the cell.
Researchers observed male chimps in Uganda's Kibale National Park using 'directed scratches' to request grooming of specific areas on their bodies. The study suggests that these primates may be capable of mental-state attribution, making inferences about the knowledge of others.
Researchers found that inhibiting CPT1A in rats improved insulin sensitivity and reduced blood sugar levels, suggesting a critical role for this enzyme in nutrient sensing. The study provides new insights into the molecular mechanisms underlying diet-induced obesity and insulin resistance.
Researchers at Ohio University found that salamanders and the ancient lizard-like animal tuatara can both walk and run on land, using energy-saving mechanisms similar to those in fast-running animals. This discovery suggests that these early vertebrates may have had a key role in shaping the evolution of locomotion in later species.
A new study identifies areas with potential species extinction risk, highlighting the need for proactive conservation efforts. Researchers found that many species currently deemed safe could leapfrog into high threat categories, emphasizing the importance of protecting vulnerable species before they become endangered.
Researchers found that a protein called Cryptochrome helps regulate the biological clock in fruit flies, similar to its role in mammals. The study provides new insights into the human biological clock and its relationship to sleep-wake cycles and overall health.
Researchers found that free-living hummingbirds in Canadian Rocky Mountains have impressive timing abilities, remembering interval between visits to individual flowers. They can maintain 'independent stopwatches' for up to eight different flowers, allowing them to plan efficient nectar harvesting
Researchers at Johns Hopkins Medicine discovered that injecting ciliary neurotrophic factor (CNTF) into obese mice with leptin deficiency or resistance reduced their heart muscle walls by up to a third and the size of the left ventricle by 41%. This breakthrough suggests a novel brain-signaling pathway for obesity-related heart failure.
Researchers at Tohoku University discovered that adding rice bran to the diets of hypertensive rats lowered their systolic blood pressure by about 20 percent and inhibited angiotensin-1 converting enzyme. The study also found that rice bran significantly lowered levels of a marker called 8-OHdG, indicating reduced oxidative stress.
UCI researchers found a compound, AF267B, reduces hallmark lesions and improves cognitive function in genetically modified mice. The compound mimics the effects of acetylcholine and binds to M1 receptors, preventing beta-amyloid production and accumulating tangles.
Researchers found that a new experimental drug, AF267B, reversed key cognitive deficits and reduced pathological plaques and tangles in the brain of Alzheimer's patients. The treatment improved learning and memory abilities in mice with amyloid plaques and neurofibrillary tangles, but not in other brain regions.
The use of animal serum-free media for growing live cells is being promoted as a more humane and scientifically superior alternative. This approach eliminates the need for fetal calf serum, reducing variables in experiments and ensuring reproducibility across laboratories.
Researchers discovered that modern birds can form teeth in embryonic stages with similar developmental positions to mammals. The talpid2 strain of chicken harbors a genetic change allowing this process.
Researchers found that male-specific gene SRY is required for normal brain function of dopamine-secreting neurons. This may help explain the higher incidence of Parkinson's disease in males, which exhibits a 3:2 ratio with females.
Childress and colleagues develop tool to simulate hovering flight in laboratory setting, allowing analysis of optimal flapping frequency with size. The researchers created a vertical oscillating wind tunnel to study the hovering of passive flexible bodies in oscillating airflow.
Researchers at the University of Pennsylvania School Medicine have created a three-dimensional neural network that can be transplanted to bridge spinal cord lesions. The construct, designed to mimic the longitudinal arrangement of the spinal cord, integrates with host tissue and maintains its geometry after transplantation.
The American Physiological Society has published a resource book on animal exercise protocols to promote informed dialogue and improve animal welfare. The book covers various aspects of exercise research, including study design considerations, animal stress, and common exercise protocols using different species.
Researchers have found that the number of senescent cells increases exponentially with age, with TIF-positive cells making up about 4% of connective tissue in young monkeys and 20% in older ones. The study confirms the importance of telomeres in aging and suggests a strong link between aging cells and body.
Researchers found evidence of increased clay mineral deposition in the oceans during a 200 million year period, which preceded the first animal fossils about 600 million years ago. The study suggests that an increase in oxygen concentration in the atmosphere was necessary for animal life to arise.
Researchers dispelled the myth that eating late at night causes weight gain. Female rhesus monkeys on a high-fat diet gained 5% more weight after having their ovaries removed, showing ovarian hormones play a role in weight balance. The study found no correlation between late-night eating and weight gain.
Researchers found that the Runx1 gene is essential for the development and function of nociceptive sensory neurons, which are responsible for sensing pain. The study reveals that Runx1 regulates the specification of these neurons and their wiring, providing a genetic basis for chronic pain.
Researchers created mice with a genetic defect that affects learning and memory, mirroring symptoms of schizophrenia. The animals struggled to adapt to new environments and scents, highlighting potential treatments for the mental health disorder.
Researchers found a correlation between armpit odor and female fertility, suggesting that volatile organic compounds (VOCs) may play a role in reproductive health. The study suggests that women with higher VOC levels in their armpits may have better fertility prospects.