Articles tagged with Animal Research
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at UNSW Sydney have developed a new technology offering test strips for rapid, on-the-spot disease detection. The test strips are accurate and cost-effective, making them suitable for various applications including public health, environmental diagnostics, and cancer cell detection.
Researchers investigated combining Sacituzumab govitecan with platinum-based chemotherapeutics for triple-negative breast cancer, urinary bladder carcinoma, and small-cell lung carcinoma. The study showed additive to synergistic antitumor effects in vitro and in vivo, with improved outcomes in tumor-bearing animals.
Researchers found that altering the starch, oil, and amino acid content of a broiler diet can help support healthy growth in coccidiosis-challenged birds. The optimal mix consists of 35.8% starch, 8.9% oil, and 101.3% recommended amino acids.
A study by researchers at the University of Wyoming and Max Planck Institute of Animal Behavior found that migrating animals refine their behavior with age, suggesting experiential learning plays a crucial role in successful migration. As young birds explore new places during migration, they gradually adopt more direct routes, resultin...
Researchers from Kyushu University and Harvard Medical School have identified proteins that can reprogram fibroblasts into cells with properties similar to limb progenitor cells. The new method simplifies the process of regenerating human limbs after amputation and could one day be used to give snakes back their legs.
Researchers discovered a group of common microbes that work together to decompose flesh, allowing for accurate time-of-death estimates. A predictive model based on microbial activity demonstrated high accuracy in predicting time of death within three calendar days.
Researchers found that brown bears' digging for cicada nymphs damages tree roots and alters soil nitrogen content, limiting tree diameter growth. This phenomenon is unique to human-planted conifer forests, with no similar effects in natural forests.
A recent study reveals how animal agriculture companies shape public discourse and policymaking in their favor, downplaying their role in climate change. Industry-funded efforts have been bolstered by collaborations with academic researchers, hindering meaningful action on climate change mitigation.
Scientists have identified a crucial role of the newly discovered ion channel Elkin1 in converting mechanical stimuli into electrical signals, enabling normal touch sensation. The findings also suggest Elkin1 may play a part in transmitting painful mechanical stimuli, opening up new potential targets for chronic pain treatment.
A new rapid test has been developed to identify hantavirus in South Korea, paving the way for early outbreak control. The Flongle sequencing-based diagnostic is cost-efficient and can detect HTNV genomes within 3 hours.
Oregon State University researchers have documented the first-ever sighting of a hoary bat flying over the open ocean, highlighting the need for further studies on threats bats face at sea. The sighting occurred in an area leased for potential offshore wind energy development.
A new study by City University of Hong Kong found that sex and social status influence social grooming among free-ranging feral cattle in Hong Kong. The research suggests that more dominant females receive more grooming, and high-ranking animals exchange more friendly grooming with each other.
A study by researchers at UNC School of Medicine found that chronic cocaine use alters the functional networks in the brain, including the default mode network and salience network. This disruption can make it harder for individuals to focus, control impulses, or feel motivated without the drug.
A University of Otago-led study found that sensory cues alone can drive ageing effects in animals. Researchers tested male mice exposed to female odours and found reduced fertility and increased mortality later in life. The study highlights the importance of sensory perception of mates in influencing life-history trade-offs.
A new protocol has been implemented, compensating loggers to leave kite nesting sites alone. The results show that 37 young raptors were saved over 7 years. This innovative approach demonstrates the benefits of dialogue between public and private sectors in conservation.
The University of Maryland School of Medicine has been awarded $3.5 million in federal funding to develop acute radiation syndrome animal models and advance the development of radiologic and nuclear countermeasures.
Two new Pacific bee species and insights into Fijian bird behavior have been described in recent scientific studies led by Flinders University. The research highlights the potential for species discovery, ecological knowledge, and cultural engagement from Asia-Pacific collaborations.
A new study reveals that ringtails prefer tree cavities in mature and older forests, rather than oak woodlands. Researchers found that the presence of fishers did not influence where ringtails chose to rest, providing important guidance for forest managers seeking to conserve these trees.
A study models habitat suitability for medically relevant black flies in four German federal states, predicting an increase in their population due to climate change. The findings suggest that the warming temperatures and changing land use could promote the growth of species with a broad niche, leading to more frequent occurrences.
The Almodóvar lab is studying the link between HIV and pulmonary hypertension, a condition that increases pressure in lung arteries. By examining the interactions between different cell types and using a humanized mouse model, researchers hope to propose novel therapies to prevent lung diseases in people with HIV.
Researchers developed a new recombinant flu vaccine called Hexaplex, which provided superior protection against H1N1 and H3N2 viruses in animal models. The vaccine's combination of six proteins from different groups resulted in strong antibody production and T-cell activation, offering broader immunity.
A new mouse study reveals that the gut microbiome interacts with the loss of female sex hormones to exacerbate metabolic disease. The research suggests that the gut microbiome contributes to weight gain, fat in the liver, and inflammation, particularly in women after menopause.
Delta opioid receptors play a crucial role in anxiety development, and research reveals its therapeutic effects in animal models. KNT-127, a DOP agonist, reduces anxiety-like behavior by suppressing glutamatergic transmission, offering new potential for treating anxiety disorders.
Researchers created novel gene editing enzymes with improved precision, reducing off-target RNA edits by over 99%. The technology has potential applications in treating mitochondrial genetic diseases and may lead to transformative treatments within the next five years.
Researchers discovered exceptionally high levels of PFAS in birds and mammals at Holloman Lake, contaminating thousands of species. The study found that even low concentrations of PFAS can cause harm to animals and people, highlighting the need for environmental action.
Researchers analyzed tissue and fecal samples from 90 stranded marine mammals to study the distribution of toxic elements. The study found that Risso's dolphins and short-finned pilot whales had high concentrations of mercury, cadmium, and lead, while dwarf sperm whales had low levels.
Researchers found that a compound called BAM15 makes mitochondria less efficient at producing energy, extending life span and improving body composition in fruit flies. The study also showed reduced age-related decline in motor activity. Further studies are needed to confirm these findings in humans.
A new study aims to enhance and prolong vaccine effectiveness by delivering adjuvants to white blood cells using lipid nanoparticles. The research, led by WVU professor Sharan Bobbala, has the potential to provide broader protection against evolving viruses and multiple diseases.
A study by UC Davis Health found that a single dose of BCG reduced liver tumor burden and extended the survival of mice with liver cancer. The vaccine boosted the body's immunity, leading to tumor shrinkage and improved liver function.
A new study from the Stowers Institute for Medical Research has discovered that sea lampreys and humans share an remarkably similar molecular and genetic toolkit in their hindbrain development. The research found a crucial molecular cue, retinoic acid, to be involved in both species' brain stem formation.
Researchers found that impaired mitochondrial unfolded protein response causes accelerated telomere shortening in both oocytes and somatic cells of aging mice. This study highlights the link between loss of mitochondrial protein homeostasis, infertility, and somatic aging.
Researchers at Texas A&M discovered that immune genes are frequently exchanged between Myotis bat species during seasonal mating swarms, potentially helping humans fight emerging diseases. The study's findings have opened new questions about the importance of hybridization in evolution and its impact on genomicists' knowledge.
The study reveals changes in motor protein structure and energy consumption during hibernation, highlighting key differences between large and small hibernators. Myosin plays a crucial role in non-shivering thermogenesis, with smaller mammals experiencing increased ATP consumption at lower temperatures.
A study by Dr Sebastian Korb at the University of Essex found that a brief weak grin makes faces appear more joyful, creating the illusion of happiness. The research used electrical stimulation to spark smiles and has potential for future clinical applications.
A new metabolomics method has been proven to be a reliable approach for grouping chemicals, potentially reducing the use of lab rats. The study's results show that the method can accurately group chemicals into categories, making it a viable alternative to traditional methods.
Studies reveal how primates modify behaviors to care for themselves and others despite physical disabilities. Behavioral flexibility is crucial, allowing them to adjust species-typical behaviors and innovate new ways to participate in daily activities.
A genetic study reveals two distinct clusters of deer populations in Nara, Japan, highlighting the need for reconciliation among stakeholders. The research emphasizes the importance of careful management to address conflicts between preserving sacred deer lineage and allowing admixture for conservation.
A Tel Aviv University study found that women in this age group experience increased AMH secretion when exposed to UV radiation from the sun. This increase in hormone levels is associated with a positive effect on fertility.
A new large-scale study finds that functional traits, not nativeness, play a key role in shaping the effects of large mammalian herbivores on plant communities. Introducing feral cattle or water buffaloes into local areas could be a good idea for complementing native deer and promoting plant diversity.
Researchers have made groundbreaking discoveries about the reproduction of giant Antarctic sea spiders, a phenomenon known as polar gigantism. The study found that these creatures do not carry their young like most other species, but instead attach them to rocks for several months before hatching.
A team of researchers used biopsies from young bulls to investigate the genes and mechanisms controlling male fertility. They found a large number of genes associated with fertility in bulls, most of which are also relevant to human male fertility.
A recent study found that exotic cats, including lions, tigers, and cheetahs, can discriminate between familiar and unfamiliar human voices. The researchers used carefully designed experiments to investigate this phenomenon, finding consistent evidence of voice recognition across 25 cats.
A recent study published in Science found that wildebeest and zebra compete for nutrient-dense grasses in Serengeti, pushing each other along in a 'push-pull' hypothesis for grazing succession. This challenges the prevailing theory of how mass-migration patterns occur in the park.
The tawny owl's pale grey plumage is linked to crucial functions aiding survival in cold environments, including energy homeostasis and fat deposition. Genetic analysis reveals a 70-100% accuracy in predicting grey coloration through specific genetic variants.
A study of human-animal co-burials from ancient Italy suggests that the practice may have been related to enduring companion relationships or religious beliefs. Researchers found that the people buried with animals did not share common traits, leaving multiple interpretations for this phenomenon.
A study published in Nature tracked neural activity of freely moving macaques using wireless eye tracking and neural monitoring. The research found that the visual cortex plays an active role in social behavior by providing signals to the prefrontal cortex, enabling the decision to cooperate.
A new study finds that red-colored agricultural nets are more effective at deterring onion thrips than traditional black or white nets. The use of red nets resulted in a 25-50% reduction in insecticide applications, making them a promising solution for sustainable agriculture.
A recent study published in Biological Conservation reveals that NY bobcat populations remain critically low, with occupancies below detectable limits. Researchers used trail cameras to monitor wildlife populations in central and western NY state, tracking white-tailed deer, red fox, coyote, eastern wild turkey, and gray fox numbers.
A Johns Hopkins Medicine-led study found rapid antigen tests for detecting SARS-CoV-2 can be used at home with accuracy comparable to clinician-administered tests. The study involved nearly 1,000 patients and showed that self-administered rapid tests rivaled clinician-administered tests in both sensitivity and specificity.
A new study from the University of Ottawa proposes using vanoxerine, a drug initially developed for cocaine addiction, to potentially treat advanced colon cancer. Vanoxerine has been found to suppress cancer stem cell activity in colon cancer patients' tissues and tumours implanted in laboratory animals. The drug works by interfering w...
A recent study found that polar bears, closely observed by scientists, struggled to maintain weight when their preferred seal prey was out of reach during longer ice-free seasons. Despite trying various strategies, including resting and foraging, nearly all the bears lost weight rapidly, highlighting their vulnerability to climate change.
Researchers found Joro spiders can thrive near busy roads, attacking simulated prey 59% of the time, despite slight differences in attack rates, without compromising their health or body mass. The species' ability to tolerate urban vibrations and sounds is likely a key factor in its exponential growth
The study reveals that the superior colliculus is vital in the transition from seeing individual flashes to smooth motion, and may be a key component in creating the continuity illusion. Different methods of measuring the Flicker Fusion Frequency threshold suggest other parts of the brain also play a role in this process.
Two new EU-funded projects, PollinERA and WildPosh, will investigate the toxicological and ecological impacts of chemical pollution on terrestrial biodiversity and pollinators. The projects will improve risk assessment tools and characterise exposure routes to pesticides in four European regions.
Researchers identified blood proteomic markers associated with hepatocellular carcinoma (HCC) in patients with cirrhosis. The study found a set of biomarkers, including TGF-β driven mechanistic biomarkers and Myostatin and Pyruvate Kinase M2, which may stratify risk for HCC.
Researchers have created the DEBBIES dataset to enhance understanding of cold-blooded animals' responses to novel environmental shifts. The dataset contains estimates of eight life history traits for 185 ectotherm species, allowing users to develop general predictions on animal responses using a few key characteristics.
Detailed CT scans reveal the worm-lizard's skull anatomy, including sutured bones and a singular central tooth. Researchers also discovered sexual dimorphism in one species, confirming their findings through powerful jaw muscles.
ATH-1105, a small molecule positive modulator of the neurotrophic HGF system, demonstrates significant neuroprotective effects and extends survival in preclinical models of ALS. The study highlights the therapeutic potential of ATH-1105 in slowing or stopping neurodegeneration.
Scientists at UC Riverside have discovered a tiny worm species that can control crop pests in warm, humid environments. The new Steinernema adamsi nematode is nearly invisible and can kill insects with a low dose, making it a potential alternative to pesticides.
Researchers found elevated PROX1 levels in advanced colon adenocarcinoma, correlating with poor prognosis. PROX1 modulates CRC cell behavior, influencing invasiveness and survival outcomes. The combined PROX1/α-SMA gene set emerges as a potential CRC prognostic marker.