Articles tagged with Vaccine Research
Child vaccination rates in Africa are significantly lower where people distrust local and national authorities. A study of 167,000 children across 22 African countries found that mistrust in courts, parliament, and government can lead to a 11% increase in unvaccinated children.
A recent study from the University of Virginia Health System found that more than a quarter of American infants in 2018 had not received all recommended childhood vaccines. Disparities were observed among African-American infants, low-income families, and those with lower education levels. The researchers warn that these gaps can lead ...
A Cornell-led research survey found that many Americans believe the Moderna and Pfizer-BioNTech vaccines provide weak protection against COVID-19 after a second dose. The study highlights the need for improved guidance on continued public health precautions, such as wearing masks, to combat vaccine attrition and prolong pandemic recovery.
A study by University of California, Davis researchers found that prioritizing vaccination for vulnerable populations like seniors and essential workers can reduce deaths, infections, and years of life lost by 17-44%. The optimal strategy depends on the outbreak conditions, including vaccine supply and transmission rates.
Researchers at Ben-Gurion University found the Pfizer vaccine to be moderately less effective against the South African variant, while still providing protection against the British variant and the original strain. The study was published in Cell Host and Microbe and suggests that future variants may require a modified vaccine.
A new study examined COVID-19 vaccine acceptance among a large national sample of sexual and gender minority men and transgender women, finding that medical mistrust, social concern, and race were significantly associated with decreased vaccine acceptance. Healthcare provider recommendations and altruistic attitudes were found to be po...
Researchers found that people preferred drive-through clinics due to perceived safety, convenience, and reduced contagion. The study suggests drive-through clinics could rapidly vaccinate large numbers of people, transforming the COVID-19 pandemic's trajectory.
A new modelling study estimates that without vaccination, mortality in children under five would be 45% higher in low-income and middle-income countries. Vaccination has prevented 69 million deaths between 2000-2030.
A new study estimates that vaccination against 10 major pathogens will have prevented 69 million deaths in low-income and middle-income countries between 2000 and 2030. Vaccination programs are expected to reduce mortality from these diseases by 72% for those born in 2019, with the greatest impact on children under five.
A study from Boston Medical Center found that using indicative language when recommending HPV vaccination boosts vaccine acceptance and conversation efficiency while preserving patient satisfaction. This approach resulted in a nine-fold increase in vaccine acceptance and shorter vaccine discussions compared to elective styles.
A recent study assessed the acceptability of COVID-19 vaccine mandates in the US public, revealing mixed attitudes towards mandates. The study found that while some individuals strongly supported vaccine mandates, others were more hesitant or opposed.
A nursing researcher reflects on her experience participating in a COVID-19 vaccine trial, discussing the importance of informing patients about possible side effects. The article emphasizes the need for clinicians to prepare their patients for vaccination, ensuring informed consent and minimizing adverse reactions.
A recent study found that a high-dose flu vaccine is equally effective to a standard dose in reducing the risk of death or hospitalizations from heart or lung-related illnesses in people with heart disease. Researchers enrolled over 5,000 participants and found no significant difference between the two vaccine formulations.
A new study suggests that localized vaccination surveillance can help predict and prevent measles outbreaks by analyzing geographic clustering of non-vaccinators. The researchers found that even at high overall vaccination coverage, clustering of non-vaccinators increases the probability and size of an outbreak.
A study found that vaccination with the measles-mumps-rubella (MMR) vaccine reduced the severity of COVID-19 in high-risk patients. Out of 36 cases, none required supplementary oxygen or respiratory insufficiency.
A new study by the International Vaccine Access Center at Johns Hopkins Bloomberg School of Public Health estimates that immunization programs will save $681.9 billion for 2011-20 and $828.5 billion for 2021-30, with a return on investment ratio of up to 51:1.
The Michelson Prizes support the innovative work of Dr. Danika Hill and Dr. Michael Birnbaum on discovering targets for long-lived humoral immunity and identifying specific antigens in HIV vaccines.
Researchers discovered that vaccinated participants were less generous to non-vaccinated individuals than to other vaccinated peers, especially among those who viewed vaccination as a moral duty. This suggests that vaccination is perceived as a societal obligation, transcending social group affiliations.
A Washington State University study found that words matter in vaccination messages, with normative and injunctive messages increasing interest and vaccine intention. Negatively worded messages can decrease interest, highlighting the importance of using effective promotional messaging to improve vaccine uptake.
Researchers found concern for others was a key driver of polio vaccination in Israel during a polio resurgence. Understanding the campaign's prosocial nature influenced vaccination behavior, highlighting the role of communication in improving outcomes.
Researchers have identified a newly found pneumococcus capsule, the 100th since its discovery, and linked it to oral streptococci. This finding underscores the need for updated vaccines that can keep pace with rapidly changing bacteria.
Researchers found that a common soil fungus can promote plant growth and boost defense responses in corn plants, suppressing pest growth. This discovery could be an valuable ally for organic corn growers facing challenges with insect control.
Research finds people with vaccine skepticism tend to overestimate the likelihood of rare negative events, including mortality-related causes. This suggests a possible explanation for their concerns: cognitive or affective variables influencing vaccine skepticism.
Research by University of Otago found significant levels of negative information about vaccines available online, including on Google, Facebook, and YouTube. Health professionals can help inform parents by referring them to credible websites containing well-validated information.
A recent study found that social media significantly increased expressions of distrust in government regarding vaccines after the 2018 Changchun Changsheng Biotechnology vaccine incident. The researchers also observed a decrease in self-reports of vaccination and expressed support for vaccine acceptance in China.
A recent study published in Clinical Infectious Diseases found that adults who completed their childhood vaccination series against tetanus and diphtheria are protected for life. The researchers compared data from millions of people across North America and Europe between 2001 and 2016, concluding that booster shots are not necessary.
A new study found that peace of mind plays a significant role in parents' attitude towards vaccines, with reassurance from knowledge of benefits and healthcare providers influencing decisions. The research suggests that decision makers should consider these benefits when making funding decisions.
Researchers propose using genomic data and mathematical modelling to design vaccines for the specific geographic location where they will be used. This approach aims to minimize rates of pneumococcal disease, a serious infection that can cause pneumonia, sepsis, and bacterial meningitis.
A California law eliminating nonmedical exemptions increased vaccination rates and restored 'herd immunity,' preventing outbreaks. The study found a 3.3% increase in MMR coverage and a 4.3% increase in overall vaccination coverage, while nonmedical exemptions decreased by 2.4%.
Researchers found that a plant-based compound called halofuginone improves the immune response to a potential dengue vaccine in mice, producing twice as many antibodies and binding more strongly. The compound mimics amino acid starvation, activating a pathway that results in better antibodies.
Researchers at Trinity College Dublin have discovered that only 17% of badgers disperse from their home territories, with females traveling long distances in search of new habitats. Understanding this behavior is crucial for implementing effective vaccination programs to limit TB transmission.
Researchers examined over 500 vaccine-related ads on Facebook and found that a small group of anti-vaccine ad buyers targeted specific audiences, while pro-vaccination ads were often rejected due to Facebook's policies. The study highlights the need for social media platforms to balance free speech with public health concerns.
Researchers detected oral HPV DNA in 6.2% of teen and young adult female participants, with detection decreasing over time since becoming sexually active. The study suggests that the HPV vaccine is less effective against certain types of oral HPV in vaccinated individuals compared to those who are fully unvaccinated.
Researchers found that oral antibiotics can alter human immune responses to seasonal influenza vaccination, potentially hindering protection against infection. Antibiotics also promoted pro-inflammatory states in the body, similar to conditions seen in older adults who have received influenza vaccines.
A University of Minnesota researcher has been awarded a $3.9 million NIH grant to develop novel vaccine strategies for cytomegalovirus (CMV), the most common infection causing birth defects and disabilities in US babies. The research aims to prevent congenital transmission of CMV by targeting pregnant women.
A study published in PLOS ONE found that individuals' vaccination attitudes are shaped by their proximity to a disease outbreak, particularly for those who distrust government medical experts. On the other hand, people with high levels of trust in government experts are not affected by disease proximity.
A new study published in Papillomavirus Research found that one dose of HPV vaccine lowers the chance of having a pre-cancerous lesion detected at cervical screening in women vaccinated at a young age. The data supports the possibility that one dose may be sufficient for protection, simplifying vaccination and potentially benefiting co...
A new shingles vaccine has been shown to effectively prevent outbreaks of the painful rash among patients who have undergone stem cell transplantation. The study found that the vaccine reduced the incidence of shingles by 68% and related complications, offering promise for patients with immune-compromising conditions.
Researchers at Drexel University found that combining HPV vaccination with condom use reduces HPV cases among young gay men. Vaccination was effective in preventing oral infections, while condoms were more effective against anal transmissions.
New research from Brigham Young University finds that exposing people to the pain and suffering caused by vaccine-preventable diseases can increase support for vaccinations. Nearly 70% of students who interviewed someone with a vaccine-preventable disease moved from hesitant to pro-vaccine attitudes.
Studies show that specific rabbit genes contribute to acquired resistance to the myxoma virus, while co-evolutionary forces drive parallel adaptation between viruses and hosts. The research demonstrates how genetic variations can lead to changes in virus pathogenicity.
Researchers from University of Barcelona analyzed Hepatitis A virus variants that can escape the effects of the vaccine. They recommend giving two doses and additional booster shots to prevent the emergence of these variants.
A recent study by FSU researchers found significant racial disparities in flu vaccine rates among adolescents. Black teens received significantly lower vaccination rates than their white and Hispanic peers. The researchers suggest targeted interventions to improve vaccination rates and reduce disparities.
Scientists identify nine new potential vaccine candidates and six new proteins that could be effective targets for new antimicrobials to combat drug-resistant gonorrhea. The study represents a key step toward developing new weapons against the ever-evolving pathogen.
Researchers in Belgium have identified an additional inoculation source for lambic beer production, the wooden casks or foeders. The microbial compositions of these surfaces differed statistically based on barrel cleaning procedures and type, reflecting different characteristics of lambic barrels.
A study by the London School of Hygiene & Tropical Medicine found a significant drop in public confidence in vaccines after the Philippines' Dengvaxia crisis. In 2015, 93% of respondents strongly agreed that vaccines are important, but this dropped to 32% in 2018.
Researchers found vaccination rates dropped significantly throughout the day at primary care clinics from 44% to 32%. Implementing a nudge in electronic health records increased flu vaccinations by nearly 20% compared to practices with no intervention.
A recent US study found that catch-up HPV vaccination in women aged 14-20 years who receive all three doses is effective against cervical precancers. The study suggests that protection is strongest when the vaccine is initiated earlier, and further research is needed for women aged 21-26 years.
A new study examines the effect of HPV vaccine on a population level, finding a significant reduction in severe dysplasia. The vaccine has been shown to work effectively in reducing cervical cancer risk, with a 40% lower incidence rate compared to unvaccinated women.
A University of Kent-led study reveals that prophylactic mass vaccination programs are not effective in preventing new Ebolavirus outbreaks. To establish herd immunity, 80% of the population would need to be immunized, which is currently unachievable.
The Scripps Research team will expand studies on broadly neutralizing antibodies that can neutralize many strains of malaria and influenza. The grant aims to design promising vaccine candidates against these diseases, which kill millions globally each year.
A study reveals that incomplete vaccination coverage is causing a predictable increase in pertussis cases. The vaccine's effectiveness decreases over time, allowing susceptible individuals to contract the disease. Researchers recommend targeting schoolchildren for vaccination campaigns.
A Kaiser Permanente study found no association between multiple vaccines and non-vaccine targeted infections in infants. The research examined 193 children with non-vaccine targeted infections and 751 control group children, concluding that vaccination does not damage the immune system.
Researchers found that constant media coverage increased vaccinations by 79% in the Jewish population and 71% among high socio-economic subgroups. Positive media sentiments also prompted an increase in polio vaccines, while negative sentiments had no noticeable effect.
Researchers discovered a new badger behaviour where some males range widely across multiple territories, gaining access to more female badgers and potentially increasing disease transmission. This finding could help pinpoint areas of high risk for TB transmission, informing effective vaccination strategies.
A recent study in northwest Pakistan found that high insecurity increases access issues for vaccinators and vaccination rates, leading to a higher incidence of polio. Regional conflict has been cited as a barrier to polio eradication, but this study provides strong evidence supporting the claim.
A new study published in BMC Medicine found that the rotavirus vaccine has a disproportionate impact on reducing gastrointestinal disease in the UK's most deprived communities. The vaccine has been shown to decrease hospitalisations and attendances by up to 80% and 32%, respectively, among these populations.
A decade-long study on hundreds of HPV vaccine recipients found the vaccine to be safe and effective in preventing the most virulent strains of the virus. The quadrivalent vaccine was virtually 100% effective in preventing disease in young individuals.
Researchers at Johns Hopkins Bloomberg School of Public Health have discovered a genetic mutation in the FluMist intranasal flu vaccine that has the potential to be altered to enhance its protective effect. The mutation reduces virus production, but reversing it makes the virus more active and induces a stronger immune response.
A Kaiser Permanente study found that pregnant women who used an interactive website monitored by a clinical expert were more likely to vaccinate their children than those without access. The study suggests websites with interactive components can complement face-to-face clinical interactions and combat misinformation.