Articles tagged with Vaccine Research
Researchers discovered that a 1966 RSV vaccine's defective antibodies failed to bind to the real virus, leading to severe disease. New findings could lead to the development of safer and more effective vaccines for RSV and other respiratory viruses.
Researchers at Temple University found that addressing ER workers' fears and concerns through targeted messages can increase vaccination rates. The study used perceptual mapping to analyze respondents' attitudes toward vaccination, revealing significant shifts under varying levels of threat.
A combination vaccine using virus-like particles (VLPs) provides complete protection against Ebola and Marburg viruses in monkeys. This innovative approach has the potential to offer broad-based immunity and is considered a leading candidate for use as a filovirus vaccine in humans.
Researchers at Baylor College of Medicine discovered that mesothelin, a protein found on tumor cells' surface, promotes pancreatic cancer growth. A new vaccine targeting mesothelin, made from virus-like particles, has shown promise in slowing tumor growth and increasing survival time in mice.
Researchers at Oregon Health & Science University have discovered a way to jumpstart the production of new naïve T-cells, which are vital for fighting infections. This approach could provide long-term protection against diseases such as the flu for aging Americans.
Researchers found that over half of vaccination-related videos on YouTube portray childhood, HPV, flu vaccinations negatively or ambiguously. A staggering 45% of these videos contradict the Canadian Immunization Guide.
A study published in Science suggests that the standard trivalent vaccine is not effective in poor sanitation and high population density states like Uttar Pradesh and Bihar, where polio persists. Using a monovalent vaccine may boost efficacy and help eradicate the virus.
A new H5N1 variant, Fujian-like (FL), has emerged in China and spread to other countries, causing increased poultry infections and recent human cases. The study suggests that the vaccination program may have facilitated FL's emergence, highlighting inadequate control measures.
A recent study suggests that prompt surveillance and containment of victims would be sufficient to thwart an epidemic in the event of a large bioterrorist US smallpox attack. Researchers found that mass pre-vaccination of the general population may not be necessary, as the benefits of vaccination are outweighed by potential side effects.
Researchers at Rockefeller University developed a modified HIV virus that can infect both human and monkey cells, paving the way for more effective vaccine testing. By manipulating key proteins, they created a 'simian tropic HIV' (stHIV) that replicates vigorously in primate cells.
OHSU researchers show that CD8+ T-cells can literally eat virus-infected cells, providing insight into the human immune system and potential new way to gauge vaccine effectiveness. The discovery may help determine vaccine efficacy by measuring T-cell response to and consumption of a candidate vaccine.
Researchers propose a $500 million upfront investment to secure a 12-month vaccine supply, protecting 11,000 daily births from potential shortages. The CDC's six-month plan is deemed unclear given the actual production interruption timelines.
A 2.5-year study involving 2,781 individuals aged 15-65 found the acellular pertussis vaccine to be safe and 92% effective in preventing the disease among adults and adolescents. The vaccine's effectiveness could help reduce transmission of the disease.
Researchers at UTSA are studying safe effective vaccine candidates for long-term immunity against tularemia, a deadly pathogen associated with a 30-40% mortality rate. The study will focus on understanding the organism's strategies to evade immune responses and develop T-cell protection.
A study found that attempts to change anti-vaccine attitudes can lead to increased opposition, damaging physician-patient relationships. Researchers discovered that after presenting evidence-based information or hearing from a polio survivor, some participants became more opposed to vaccination.
A study found that many US children are undervaccinated or have delayed vaccinations in their first 2 years of life. The researchers discovered that on average, children were undervaccinated for 172 days during this period.
The Alliance for Taxpayer Access urges NIH to provide timely and complete access to its research, citing the importance of public investment in medical innovation. A delayed announcement on enhanced public access to NIH research has disappointed patient advocates and researchers.
A DNA vaccine has been shown to protect against anthrax, with the protective antigen (PA)-based vaccine proving more effective than the lethal factor (LF)-based vaccine. The study found that immunization with PA induces antibodies capable of neutralizing toxin and conferring protection.
Research found a 10-20% point gap in vaccination rates between blacks and whites, even after adjusting for socioeconomic factors. The study suggests that culturally appropriate messages and additional resources are needed to improve flu vaccination rates among underserved communities.
A new study published in The Lancet found that the meningococcal C conjugate vaccine (MCCV) may increase relapse rates of nephrotic syndrome in children with kidney disease. The vaccine was introduced to all UK children under 18 years old in 1999, but subsequent monitoring revealed a 30% increase in relapses post-vaccination.
Researchers at UCSD School of Medicine have demonstrated that pneumococcal vaccination can reduce the extent of atherosclerosis by 21 percent in laboratory mice. This breakthrough provides insight into the biological role of immune responses and offers potential therapeutic interventions for this complex disease.
The American Association for Cancer Research (AACR) has awarded several prestigious grants to outstanding cancer researchers. The AACR-National Foundation for Cancer Research Professorship in Basic Cancer Research supports Dr. Manuel Perucho's research on gastrointestinal cancer mechanisms. Additionally, the AACR-Gertrude B. Elion Canc...
A study found that many doctors' offices struggled to consistently obtain enough Prevnar vaccine, with over half reporting they had run out completely in the past year. The nation's 'patchwork' system of vaccination, driven by varying state practices and private insurance, contributed to these inconsistencies.
Researchers found that the absence of the SAP gene impairs the immune system's ability to recognize and react to infection, leading to impaired long-term antibody responses. The study has implications for vaccine development and may offer therapeutic benefits in treating X-linked lymphoproliferative disease.
A study found that acidified calcium sulfate is effective in killing Listeria on the surface of cooked products and preventing its regrowth. The treatment was shown to be safe and did not affect the taste or texture of the product, making it a potential solution for improving food safety.
Researchers have developed a sepsis vaccine that provides outstanding protection by reducing inflammatory chemicals by nearly 95%. The vaccine targets endotoxins, which trigger the immune system's response to infection.
A study by Kansas State University researchers has linked anthrax vaccination to poor health outcomes in Gulf War veterans, suggesting that the combination of vaccinations and medications may have adverse effects on susceptible individuals. The research also found that falsified or destroyed medical records made it difficult to assess ...
A recent study suggests that methionine, a chemical found in beta-amyloid protein, may play a role in slowing the progression of Alzheimer's disease. Vitamin E's antioxidant properties appear to destroy free radicals produced by amyloid, providing a possible explanation for its link to slowing the disease.
Distributed computing is revolutionizing the way scientists solve complex computational problems, enabling breakthroughs in astronomy and biology. The Stanford-led project Folding@home has taken off, with over 10,000 volunteers contributing their home computers to protein folding research.
A study found that family caregivers of dementia patients experience a decline in immune responses after vaccination, suggesting they may be more susceptible to illnesses like pneumonia and flu. Chronic stress is believed to play a role in this impairment.
The conference will examine the latest research efforts towards understanding and treating neurodegenerative diseases. Novel approaches using stem cells, vaccines, gene therapy and hormone modulation will be discussed.
Researchers at the University of Florida have developed a new treatment method using carbon dioxide to eliminate bacteria from fresh fruit juice, preserving its flavor and appearance. The process is as effective as heat pasteurization in reducing pathogens, but without the undesirable taste change.
Researchers have identified a viral protein responsible for Ebola-induced internal bleeding. The discovery could lead to the development of targeted antiviral treatments and vaccines to prevent the disease. By understanding how the virus attaches to and enters cells, scientists can design more effective countermeasures.
Mothers prefer family practice vaccinations over clinics, citing lack of empathy and pain from vaccination as reasons. Health professionals who acknowledge distress and engage with babies are valued most by mothers, research suggests.
A University of Michigan cancer vaccine combination with interleukin-2 was found to be effective in mobilizing the immune system to attack and destroy malignant cells. Eighty percent of mice showed complete regression of their tumors after treatment.
Researchers have developed a nasal vaccine that could protect people from pneumonic plague, the disease responsible for the Black Death. The vaccine, which targets tissue lining the gut and respiratory system, has shown promising results in mice trials.
Researchers at UT Southwestern Medical Center discover that telomerase causes human cells to retain their youth and continue dividing beyond their normal limit. The extension of normal cell lifespan in a youthful state presents numerous opportunities for biotechnology and medicine, including producing engineered products in human cells.
A new study suggests that an individual's control over exercise intensity and duration can affect the immune system. Voluntary exercise was found to strengthen the immune system without stress, while forced exercise led to suppression.
A recent study reveals that in 24 out of 28 cases involving Americans released from prison based on DNA evidence, eyewitnesses made false identifications from photo spreads and lineups. New research is helping to understand the circumstances leading to these errors and find ways to reduce their occurrences.
Researchers tested bovine tuberculosis diagnosis methods, finding similarities in cattle responses to three tuberculins. Swine were found susceptible to M. bovis infection through meat consumption.