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Science News for December 17, 2007


Z-shaped incision enhances minimally invasive surgery

Researchers at Penn State developed a novel surgical technique using a Z-shaped incision to access the stomach, promising reduced bleeding and complication rates. The technique has potential applications in minimally invasive surgeries, such as intestinal bypass surgery and organ biopsies.

SourcePenn State·JournalGastrointestinal Endoscopy·DateDec 17, 2007

New strategy to cut heart attack risk is effective in initial test

A new drug has been found safe and effective at reducing levels of 'bad' LDL cholesterol by up to 40 percent, a promising approach for treating high cholesterol and related conditions. The drug accelerates the natural process of ridding the body of LDL, offering an alternative to statins and potentially complementing their use.

SourceUniversity of California - San Francisco·JournalProceedings of the National Academy of Sciences·DateDec 17, 2007

Robotic device appears useful for surgical removal of cancer involving the tonsils

A new robotic surgery technique called transoral robotic surgery (TORS) has been shown to be effective in removing tonsil cancer with minimal complications and improved patient outcomes. In a study of 27 patients, surgeons successfully removed all cancerous tissues in 93% of cases, with an average surgery time of one hour and 43 minutes.

SourceJAMA Network·JournalArchives of Otolaryngology - Head and Neck Surgery·DateDec 17, 2007

For babies with heart defects, death risk is far lower at most experienced hospitals

A national study suggests that infants with complex congenital heart defects have a lower risk of dying if treated at experienced hospitals. The study found significant differences in mortality rates depending on the number of procedures performed at each hospital, with centers treating more cases having lower mortality rates.

SourceMichigan Medicine - University of Michigan·JournalPediatric Cardiology·DateDec 17, 2007

Poultry workers at increased risk of carrying antibiotic-resistant E. coli

A recent study by Johns Hopkins Bloomberg School of Public Health reveals that poultry workers in the US are 32 times more likely to carry gentamicin-resistant E. coli bacteria than others outside the industry. The study highlights the importance of non-hospital environments in the origin of drug-resistant infections.

SourceJohns Hopkins Bloomberg School of Public Health·JournalEnvironmental Health Perspectives·DateDec 17, 2007

Fundamental discovery by Einstein researchers reveals how fat is stored in cells

Scientists at Einstein College of Medicine identified two genes crucial for packaging fat into lipid droplets. Overexpressing these genes led to a significant increase in lipid droplet formation, while suppressing one of the genes resulted in a drastic reduction. This discovery could lead to new strategies for treating obesity and rela...

SourceAlbert Einstein College of Medicine·JournalProceedings of the National Academy of Sciences·DateDec 17, 2007

Agent orange chemical, dioxin, attacks the mitochondria to cause cancer, says Penn research team

Researchers at the University of Pennsylvania have identified that dioxin targets the mitochondria, disrupting normal cellular function and promoting tumor progression. The study's findings suggest that understanding this mechanism could lead to new ways to block the propagation of mitochondrial stress signaling and inhibit cancer growth.

SourceUniversity of Pennsylvania·JournalProceedings of the National Academy of Sciences·DateDec 17, 2007

Study shows urban sprawl continues to gobble up land

A new study suggests that urban sprawl has continued to grow significantly in the US over the past few decades, particularly in exurban areas. The research found significant increases in fragmentation of land use patterns, with housing development juxtaposed with agricultural or forested areas.

SourceOhio State University·JournalProceedings of the National Academy of Sciences·DateDec 17, 2007

CSHL scientists identify and repress breast cancer stem cells in mouse tissue

Researchers at CSHL have identified and repressed breast cancer stem cells in mouse tissue by manipulating microRNAs, suggesting a potential therapeutic target for breast cancer treatment. The study found that the delivery of the microRNA let-7 to breast-tissue cells can help distinguish stem-like tumor-initiating cells from other cells.

SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateDec 17, 2007

The blood-brain barrier: A misunderstood key to finding life-saving cures to brain disease

An international team of scientists proposes strategies to overcome obstacles posed by the blood-brain barrier, a gate-keeping system protecting the brain from toxins and letting in nutrients. The review article highlights the importance of understanding the blood-brain barrier in treating brain diseases such as Alzheimer's, multiple s...

SourceSaint Louis University·JournalThe Lancet Neurology·DateDec 17, 2007

New property found in ancient mineral lodestone

Researchers at Rice University have discovered a surprising new electronic property in magnetite, a well-studied magnetic mineral, by using nanofabrication methods. They were able to get the material to revert from an insulator to a conductor at temperatures colder than minus 250 degrees Fahrenheit.

SourceRice University·JournalNature Materials·DateDec 17, 2007

Massage may help ease pain and anxiety after surgery

A 20-minute evening back massage was found to decrease pain intensity and unpleasantness, as well as anxiety, in patients undergoing major surgery. The study suggests that massage may act through multiple mechanisms, including relieving anxiety and generating mood-boosting endorphins.

SourceJAMA Network·JournalArchives of Surgery·DateDec 17, 2007