Articles tagged with Discovery Research
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A team of international researchers has developed a globally-applicable ethical code for ancient human DNA research, aiming to address social and cultural implications. The code proposes cooperation with stakeholders, minimal damage to human remains, and respect for indigenous communities' perspectives.
Researchers discovered that naked mole-rats rapidly decrease uncoupling protein 1 (UCP1) in brown adipose tissue to conserve energy in hypoxia. This mechanism may hold secrets for humans to survive and thrive in low-oxygen environments, particularly in relation to diseases like stroke and chronic pulmonary disorders.
Researchers at Durham University have developed a sugar-containing polymer coating that can repair damaged artificial joint implants by mimicking the way cartilage works to lubricate human joints. The coating uses water to create a slippery surface, protecting the surfaces from wear and tear.
A study published in Frontiers in Psychology found that false information in both native and second languages equally contribute to the formation of false memories. The researchers used an online experiment with participants speaking Russian and English to assess the influence of misinformation and source misattribution on memory recall.
Astronomers have discovered an ultrahot Jupiter, TOI-2109b, with a record-breaking 16-hour orbit. The planet is estimated to be around 5 times the size of Jupiter and has a day side temperature of approximately 3,500 Kelvin.
A new 'image analysis pipeline' called TDAExplore gives scientists rapid insight into how cells are changed by disease, using a combination of microscopy, topology, and artificial intelligence. This approach can provide objective information on cell changes, such as the movement of proteins like actin, even with limited training data.
A UBCO study found that psychedelic microdosing significantly reduces symptoms of anxiety and depression in adults. The study, which followed over 8,500 participants from 75 countries, suggests that microdosing can be a valuable tool for mental health treatment.
Scientists have discovered a 900-mile mantle pipeline stretching from the Gal ªgapos Hotspot to Central America, suggesting that hotspots are not fixed in place. This new finding transforms our understanding of geologic processes occurring beneath the Earth's surface.
The WVU-led Dolly Sods GPU cluster enables researchers to accelerate computational research in fields like drug development, interstellar phenomena, and biometrics. The cluster will facilitate the analysis of massive datasets and enable real-time processing of signals from satellites in space.
A novel gene therapy has shown sustained expression of clotting factor VIII, leading to a reduction or complete elimination of bleeding events in patients with hemophilia A. The trial demonstrated improved production of coagulation factor VIII over prolonged periods.
Researchers at Lawrence Berkeley National Laboratory have developed a new approach to modify the surface of copper catalysts, improving the conversion of carbon dioxide into useful fuels. The technique involves coating the copper with thin films of ionomers, which steer the reaction towards generating carbon-rich products.
The discovery proposes replacing carbon-hydrogen bonds with nitrogen rings, enabling faster and more efficient production of drug candidates. This breakthrough could lead to rapid creation of potent and effective medication libraries.
Researchers at Tel Aviv University conducted a cross-adoption experiment with fruit bat pups to determine whether boldness is genetic or learned. The findings indicate that the pups behave like their adoptive mothers, not biological mothers, suggesting that boldness is an acquired trait passed on through mother's milk.
The new project aims to bridge the gap between complex rare category analysis and state-of-the-art techniques. It will focus on developing explainable methods for detecting defective silicon wafers and severe complications among diabetes patients.
Researchers discover that finger snaps produce the highest rotational accelerations observed in humans, even faster than professional baseball pitchers. The study explores the role of friction and finds a 'Goldilocks zone' necessary for optimal energy storage.
A URI researcher has published a series of articles in the journal Biological Invasions to address concerns about diversity, equity and inclusion. The study found that the editorial board was overwhelmingly American and white, with most papers published by Americans and Europeans.
Scientists are using peptide nucleic acids to study SARS-CoV-2 RNA pseudoknots, a crucial mechanism for viral replication and translation. Understanding this process could lead to new methods to disrupt it, potentially leading to more effective treatments.
Researchers identified areas of the infant visual cortex that already show strong preferences for faces, bodies, or scenes, similar to those in adults. This challenges the traditional view that these regions take years to develop, suggesting a more rapid emergence of specialized brain structures.
A study published by Sanford Burnham Prebys found unappreciated changes in brain cell types involving hundreds of thousands of never-before-seen RNAs in individuals with Down syndrome. This breakthrough provides new avenues for understanding both Down syndrome and Alzheimer's disease.
Researchers used seabird prey data to inform fisheries management and assess the impact of the COVID-19 pandemic on the marine ecosystem. The study revealed a surge in anchovy populations and changes in rockfish recruitment, informing ecologists and fisheries managers.
Researchers at Lancaster University examine the use of AI in the food sector, highlighting the need for trusted data collaboration to reduce waste and increase sustainability. They also warn about potential ethical issues and unexpected consequences of new technology.
Researchers from the University of Copenhagen have discovered that naturally acquired immunity to malaria works differently than immunity following vaccination. The immune system uses natural killer cells to fight the parasite, which is more tailored to the disease than other typical infections.
Researchers found that specifying a shorter deadline increases response rates, while long deadlines allow people to procrastinate and forget. No deadline led to the most responses, suggesting that removing urgency leads to inaction.
A new study led by University of Minnesota Medical School researcher Xavier Revelo found that macrophages play a role in protecting the heart after injury. The research team discovered a large increase in cardiac macrophages early in response to a cardiac injury similar to high blood pressure.
A study by West Virginia University researcher Sunil Sharma found that rural COVID patients who end up in an intensive care unit are more likely to die within 30 days compared to their urban counterparts. The researchers also discovered that rural patients with COVID-linked ARDS have a higher mortality rate, even when controlling for d...
Researchers discovered inhibiting or genetically deleting the MTHFD2 enzyme reduced disease severity in various inflammatory disease models. This suggests that MTHFD2 function is important for immune cell regulation, particularly for T cell subsets involved in inflammation.
A new species, Brighstoneus simmondsi, with a distinctive bulbous nose has been identified by University of Portsmouth and Natural History Museum scientists. The discovery was made through meticulous analysis of Iguanodon bones found on the Isle of Wight, which revealed subtle differences indicating a new species.
A 13-year study tracked 21,000 young drivers and found that those who took part in a resilience program were 24% less likely to have any crashes and 42% less likely to crash at night. The program addressed common youth risks like alcohol and drugs, promoting a culture of safety.
Scientists discovered an important protective response in the heart that can prevent excessive scarring after a heart attack. The study found that this reactive response can limit cardiac fibrosis by preventing oxidant build-up in heart cells, potentially leading to new therapies to repair scarring damage.
Scientists at NTU Singapore develop a new electrochromic window material that can block up to 70% of infrared radiation while allowing 90% of visible light to pass through. The material is designed to be energy-efficient and durable, with improved performance compared to existing technologies.
A new Digital Solutions Hub will provide a gateway to interconnected toolkits and resources, integrating existing data sources on pollution, flooding, biodiversity, geology, carbon capture, and environmental health. The hub aims to improve decision-making by providing cross-sectional data for informed decisions in various sectors.
Paxlovid demonstrates significant efficacy against SARS-CoV-2 virus, reducing hospitalization and death risks in adult patients by up to 89%. The treatment's development involved cutting-edge X-ray technology from the Advanced Photon Source.
Researchers found that levels of chitinase 3-like-1 increase with age and co-morbid diseases, augmenting SARS-CoV-2 infection. A therapeutic antibody blocks the induction of the ACE2 receptor, potentially paving the way for COVID-19 prevention and treatment.
Researchers discovered a new biomarker, inactive AMPK (lo-P-AMPK), that may predict immune evasion in lung cancer. The finding could enable better personalized care for lung cancer patients by identifying those most likely to benefit from immunotherapies.
A rare collection of non-returning boomerangs from Cooper Creek, South Australia, has been analysed, revealing a diverse range of activities and daily lives of Aboriginal people. The artefacts date back to circa 1650–1830 AD and were likely used for fighting, hunting, digging, fire management, and possibly in ceremonies.
A new study suggests that black holes grow in lockstep with the expanding universe, a phenomenon called cosmological coupling. This idea improves the explanation for large black hole masses observed in gravitational wave observatories.
A 26-year study on wild white-footed mice found that mice with physical impairments survived and thrived at a rate similar to their unimpaired counterparts. Mice with impairments had greater mass and larger home ranges, but no evidence of decreased fitness.
Researchers at Children's Hospital of Philadelphia have developed a novel therapy that targets proteins essential for tumor growth and survival. Using a multi-omics approach, they identified peptides unique to neuroblastoma tumors, which are then targeted by peptide-centric chimeric antigen receptors (PC-CARs).
Researchers at Tel Aviv University discovered a central mechanism in plants that helps them deal with drought conditions and water shortages. They found that the ABA signal molecule is stored in inactive state in leaves and released under desired conditions, allowing plants to rapidly respond to changing environmental conditions.
A new analysis finds that 67 million US adults identify as disabled, with significant disparities among different socioeconomic and demographic groups. The study highlights the need for accurate data on disability to inform effective policies and solutions.
A new study by Lancaster University identifies four major concerns that hinder the adoption of reusable packaging: affordability, digitalization challenges, regulatory hurdles, and data collection limitations. To address these concerns, researchers propose implementing a track and trace system using unique barcodes to enable businesses...
Researchers at the University of Queensland have developed a method to produce unbreakable screens using liquid-phase sintering of lead halide perovskites and metal-organic framework glasses. This breakthrough could revolutionize the display industry with virtually indestructible displays.
A multidisciplinary team of researchers used a new X-ray technique to discover zinc-containing nanoparticles lodged within the wooden hull of the Mary Rose, leading to its deterioration. The nanoparticles, likely from anaerobic bacteria, have been found in conjunction with polymer deposits that were added to preserve the ship's remains.
Researchers found that future goals are represented by a pattern of neural activity resembling previous visits, and this activity can re-emerge upon decision to target a location. The orbitofrontal cortex plays a key role in representing future goals during navigation.
A five-year study aims to identify hormone responses in a population of Mexican Americans with prediabetes, Type 2 diabetes, and obesity. The research uses genetic data and physiologic testing to guide optimal treatments for diabetes, prediabetes, and related diseases.
A new study suggests that human presence on the Falkland Islands dates back to around 3450 B.C.E., with evidence of fire activity and stone projectile points consistent with Indigenous South American technology. The research indicates that people likely visited the islands for short-term stays, leaving few cultural materials behind.
A new beaked whale species has been discovered and named after Māori whale expert Ramari Stewart, highlighting the importance of Indigenous knowledge in scientific discovery. The species, Mesoplodon eueu, was found in South Africa and features a unique name that reflects its Indigenous roots.
A promising new antimalarial compound has been discovered in a collaboration between McMaster University and the University of Hamburg. The compound, duocarmycin PDE-I2, shows potent malaria-killing properties without the adverse effects of previously known compounds.
A Harvard University study estimates Americans perform about 30 minutes less moderate-to-vigorous physical activity daily compared to 200 years ago. The decline is attributed to technology, with researchers using historical body temperature records as a 'thermometer' of population-level physical activity.
SMART researchers have discovered a practical method to overcome current challenges in the manufacture of indium gallium nitride (InGaN) LEDs with considerably higher indium concentration. The new approach uses intrinsic defects in semiconducting materials to form quantum dots that emit long-wavelength light.
A computer model developed by the University of Surrey researchers supports Bernard Williams' 40-year-old hypothesis that pressure changes cause fluid in the cavity to 'slosh', generating stress in the spinal cord tissue. The study shows that this process can lead to small cavities gradually expanding down the spinal cord.
Researchers developed a graphene-based electrode, the sutrode, to modulate spleen function and immune response in diseases like rheumatoid arthritis and sepsis. The device can control different terminal nerves, increasing precision in organ function regulation.
A new study revealed that global guidance for preventing Surgical Site Infections (SSI) is not effective and needs revision. The FALCON trial found no superiority of interventions like alcoholic chlorhexidine skin preparation and triclosan coated sutures over lower-cost alternatives.
A new study reveals that rural Americans face significant challenges in accessing COVID-19 treatment trials, with many living more than an hour away from the nearest trial site. Native Americans and Alaska Natives are particularly affected, with over 50% living more than 60 minutes from a trial site.
Researchers discovered a novel topological edge soliton that inherits topological protection from its linear counterpart, enabling robust and localized light beams. This breakthrough is achieved through nonlinear photorefractive lattices harnessing the valley Hall effect, without requiring an external magnetic field.
A team of scientists led by University of Hawaii at Manoa has discovered a newly-formed planet, 2M0437b, which can be directly observed. The planet is estimated to be several times more massive than Jupiter and formed with its star around the time of main Hawaiian Island emergence.
Researchers aim to generate a model of brain-fat communication system to regulate metabolism during environmental challenges. The study uses cutting-edge techniques like immunolabeling-enabled imaging to identify new components of neural circuits controlling brown and white fat tissues.
Aging affects bilateral coordination, particularly anti-phase movement, by altering alpha and beta neural activity. Researchers discovered that older subjects displayed lower synchronization between sides of the body during anti-phase movements, making such tasks more challenging.
A 'raptor-like' dinosaur was actually a timid, long-necked herbivore, according to recent reanalysis of fossil footprints found in an Australian coal mine. The Prosauropod, a plant-eating dinosaur with legs about 1.4 metres tall and a body length of six metres, is the earliest evidence of its kind in Australia, marking a 50-million-yea...
Researchers discovered carbon residue in ancient ruby, indicating early life presence, and graphite changed surrounding rocks' chemistry for favourable conditions