Articles tagged with Discovery Research
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers developed a novel wearable soft robotic armband that conveys artificial sensations of touch to prosthetic hands, enabling users to control multiple grasp functions simultaneously. The study showed improved time efficiency and precision in transporting objects, with haptic feedback being crucial for tasks.
Researchers discovered a 150-million-year-old dinosaur with evidence of an avian-style respiratory infection, providing insight into ancient diseases. The study suggests that sauropod dinosaurs may have been susceptible to fungal infections similar to aspergillosis.
The ALS Canada Research Program has awarded nine Discovery Grants to investigate critical areas of disease processes and clinical care. The grants will support fundamental laboratory research, biomarker studies, and clinical trials.
A new study by the University of Arizona has identified a brain region and neural circuitry that mediate satiation, making it possible to create treatments with fewer side effects for eating disorders and weight management. The parasubthalamic nucleus plays a key role in regulating feelings of fullness after eating.
Researchers have discovered two new and unusual species of diatoms that fix nitrogen, a critical process supporting productivity in nutrient-poor open ocean waters. These diatoms harbor symbiotic cyanobacteria that convert dissolved nitrogen gas into ammonia, enabling them to thrive in nutrient-poor conditions.
Researchers at University of Maryland Center for Environmental Science found that marine snow particles help remove carbon dioxide from the atmosphere, contributing to a more efficient carbon cycle. The discovery sheds light on how oxygen deficient zones play a crucial role in the Earth's carbon cycle.
Researchers have developed a new therapeutic approach to block mutated RAS proteins, which are frequently found in cancers. The method, using small molecules, has the potential to work with multiple mutant forms of RAS in various types of cancers, including pancreatic, lung, and colorectal cancers.
Researchers at PSI's Laboratory for Muon Spin Spectroscopy have discovered strong evidence of exotic charge order and orbital currents in a correlated kagome superconductor. The findings provide a new insight into unconventional superconductivity and its relationship with the quantum anomalous Hall effect.
A national study found that states with higher labor underutilization, non-Hispanic white populations, and opioid prescriptions had higher SIM rates. States with centralized medicolegal death investigation systems detected more SIM cases due to toxicologic testing.
Researchers have confirmed an inhaled vaccine provides long-lasting protection against SARS-CoV-2 and its variants by targeting the lungs and upper airways. The vaccine induces broad respiratory mucosal immunity, outperforming traditional injected vaccines in terms of efficacy and dose requirements.
A comprehensive 'vertical map' of airborne microorganisms has been created, showing that temperature is the single most important factor influencing their composition. As global temperatures rise, this could lead to significant changes in the air microbiome, affecting human health and food security.
A team led by Case Western Reserve University discovered the novel repair properties of Gasdermin B protein, promoting restoration of epithelial layers and effective wound-healing. The findings have significant implications for designing therapeutics to enhance wound repair in various organs.
A new study using advanced radar technology has recorded Antarctic glaciers losing ice at unprecedented rates, threatening global climate risks. The research team plans to expand its findings to giant and fragile West Antarctica neighbors, including the Thwaites and Pine Island glaciers.
A recent study from Edith Cowan University found that even brief periods of weightlifting, such as three seconds a day, can increase muscle strength. The research involved 39 healthy university students performing isometric, concentric, or eccentric bicep curls for three seconds daily over four weeks.
Researchers at San Diego State University have discovered a novel way bacteria infect cells by producing long threads, which grows up to 100 times the size of a bacterium in 30 hours. This mechanism allows the bacteria to rapidly infect multiple cells and access more nutrients for growth.
Researchers at Wellesley College found that people frequently misinterpret bar graphs, with one in five graph readers categorically misunderstanding averages. The 'bar-tip limit error' occurs when viewers interpret the tip of the bar as the outer limit of the data, despite the average being the balanced center point.
A study by Academic Analytics Research Center found a significant increase in journal article publications (64%) and decrease in book publications (34-54%) across 12 Social Sciences disciplines from 2010 to 2020. This shift may impact library acquisitions strategies and affect humanities-related fields.
A new cloud-based data resource has been developed to help identify new subtypes of amyotrophic lateral sclerosis (ALS), a fatal neurological disorder. The tool, part of the Answer ALS collaborative effort, uses biological and clinical data from over 1,000 patients to better understand the disease.
Researchers discover unique bat-pollination system in Fiji's kuluva trees, highlighting co-dependence between species and urgent conservation needs. The novel chiropteropisteusis system sheds light on the evolution of flowering plants and threatens tree and bat species.
Research from the Dunedin Multidisciplinary Health and Development Study finds that prolonged cannabis use leads to over-inflated lungs and increased airway resistance, impairing oxygen extraction. This effect is distinct from tobacco use and may reflect early signs of a severe form of emphysema.
The collaboration aims to create an interoperable global data ecosystem for rare diseases, accelerating the development of new therapies. This partnership benefits patients, regulators, advocacy stakeholders, researchers, and industry, while expanding C-Path's global capabilities in collaborating on methodologies and technologies.
Researchers have discovered that a small protein called glucagon-like peptide-1 (GLP-1) couples the body's control of blood sugar and blood pressure. This finding could lead to new treatment strategies for patients with hypertension and/or diabetes.
Researchers discovered increased activity in the hippocampus during anesthesia and sleep, preceding Alzheimer's symptoms by years. This abnormality may enable early diagnosis and treatment of the disease.
Researchers from McGill University found that oxygen levels rose with complex eukaryotic ecosystems, indicating low oxygen was a significant limitation on evolution for billions of years. The discovery has implications for searching for biosignatures in other planets, focusing on ozone detection.
A new 'Goldilocks Zone' has been discovered in the Earth's crust, allowing critical metals like gold, copper, and tellurium to pass upwards. This finding sheds light on planetary cycles of metals and could enable more targeted mineral exploration, reducing environmental impact.
Researchers discovered a key growth factor protein, HB-EGF, produced by immune-regulating cells that protects the gut against inflammatory bowel disease. ILC3s produce HB-EGF to counteract TNF-induced inflammation and maintain gut barrier function.
A new global dataset reveals approximately 73,000 tree species, highlighting the vulnerability of global forest biodiversity to climate change and land use. The research, led by Professor Andy Marshall, also identifies a 'hot spot' of likely undiscovered species in northeast Australia and the Pacific Islands.
Scientists have identified a peripheral mechanism that allows fruit flies to quickly assess complex odors without costly synaptic computation. The fly's olfactory receptor neurons communicate through electrical interactions, enabling an energy-saving way to process meaningful odor blends.
A new study published in Clinical Nutrition found that drinking less than the UK's recommended 14 units of alcohol per week increases the risk of cardiovascular events. Moderate alcohol consumption is associated with a 23% increased risk of suffering a cardiovascular event for every additional 1.5 pints of beer consumed.
A new species of leafhopper, Phlogis kibalensis, has been discovered in the Kibale National Park in western Uganda. The insect belongs to a rare genus that was last recorded in Central African Republic in 1969.
A Rutgers study found measurable airborne SARS-CoV-2 RNA in the air of most homes where COVID-19 infected individuals were isolating, suggesting airborne transmission beyond isolation rooms poses a risk to other occupants. The study also showed that infected individuals often did not strictly adhere to self-isolation protocols.
Dr. John Pierce Wise leads a team to investigate chromosome instability in lungs caused by metal exposure, with hopes of preventing and reversing lung cancer in people. The research aims to understand why humans are more susceptible to metals-induced lung cancer than whales.
Researchers at Durham University have identified a medieval text written by Benedictine monk Gervase of Christ Church Cathedral Priory as the earliest known account of ball lightning in England. The description, composed around 1200, matches historical and modern reports of the phenomenon.
A new dataset examines publication patterns across 170 academic disciplines to provide more nuanced comparisons. The data reveals significant variation in publishing activity and venue preferences among scholars.
A recent study led by the University of Texas at Austin has found that liquid water detected under Mars' ice-covered south pole is likely a dusty mirage. However, the researchers suggest that ancient lakes and riverbeds may still be present on the planet, offering clues about its wetter past.
A longitudinal survey of over 3,000 adolescents aged 11-14 found that supportive relationships with family and friends, physical activity, and better sleep helped shield against the pandemic's negative impact on mental health. Girls were more likely than boys to experience psychological distress during the pandemic.
Researchers at the University of Leicester have partnered with BHP to identify new areas for nickel and copper deposits critical to the electric vehicle (EV) revolution. The project aims to challenge current understanding of the nickel mineral system, potentially opening up new exploration search space globally.
The Nutrition for Precision Health study will use data from 10,000 participants to develop algorithms predicting individual responses to food and dietary routines. The goal is to create more personalized nutrition recommendations and reduce health disparities.
The Epstein Family Foundation has donated $50 million to USC and UC San Diego to accelerate Alzheimer's research and discover effective therapies for the disease. The collaboration aims to compress study design, patient recruitment, and clinical trials to expedite the discovery of better treatments and a cure.
Researchers found that levitating ice requires a significantly higher temperature threshold than liquid water, with the meltwater layer creating a temperature differential that consumes most of the surface's heat. This results in a larger temperature window for boiling, leading to better heat transfer compared to using a liquid alone.
The NIH is awarding $170 million to clinics and centers for a precision nutrition study that will develop algorithms to predict individual responses to food and dietary routines. The Nutrition for Precision Health study will recruit 10,000 participants from the All of Us Research Program.
Researchers found that small groups of scientists are key in generating emerging topics in life sciences and medicine. The study analyzed PubMed data and author lists to identify past and current emerging keywords, revealing that smaller teams with fewer publications were crucial for generating high-performance keywords.
The new BD CellView Image Technology enables high-speed sorting of individual cells based on detailed microscopic analysis, accelerating discovery research in immunology, cell biology, and genomics. This technology has the potential to unlock new cell-based therapeutic discoveries and transform various fields of biomedical research.
The Microbiome and Metagenomics Center at UC San Diego will analyze stool samples from 10,000 All of Us Research Program participants to develop algorithms predicting individual responses to food. This will enable personalized nutrition recommendations based on an individual's genetics, gut microbes, and lifestyle factors.
The discovery of single-walled zeolitic nanotubes by researchers at Georgia Tech, Stockholm University, and Penn State University has the potential to revolutionize the field of materials science. The team found a unique arrangement of atoms in the zeolite nanotube walls that allows it to form as a 1D tube rather than a 2D or 3D material.
Scientists have developed a novel CRISPR-Cas3 editor from the bacteria Neisseria lactamica that improves editing efficiency and is more easily produced. The tool enables 50% editing efficiency in stem cells and 95% efficiency in other human cell lines, paving the way for research in genetic diseases and developmental biology.
The study found that efficient metabolic processes and recycling of components used by the enzyme RuBisCO significantly speed up photosynthesis in Chlorella ohadii. This discovery could lead to improving photosynthesis efficiency in other plants, developing new engineering tools for sustainable food production.
An international team led by the University of Ottawa has published findings on the importance of the enzyme GCN5 in maintaining muscle integrity. The study discovered that GCN5 plays a crucial role in boosting the expression of key structural proteins, notably dystrophin.
Scientists at Scripps Research have devised a method that can rapidly characterize antibodies using high-resolution, low-temperature electron microscopy (cryo-EM). This technique enables the identification of specific antibodies in fraction of time needed for traditional approach.
A new project aims to improve the performance of Graph Neural Networks (GNNs) by leveraging weak supervision and additional information. The research has potential applications in fraud detection, agriculture, and cancer diagnosis.
Epidemiologists have developed a new blood test, DunedinPACE, to measure biological aging. The test uses DNA methylation marks to track changes in organ-system integrity over time, predicting future disease and mortality.
Researchers at the University of Surrey have successfully demonstrated the use of multimodal transistors in artificial neural networks, achieving practically identical classification accuracy as pure ReLU implementations. The study paves the way for thin-film decision and classification circuits, which could be used in more complex AI ...
Fibrodysplasia ossificans progressiva (FOP) may be rooted in impaired and inefficient muscle tissue regeneration, which enables unwanted bone growth. This discovery could lead to new therapies targeting both extra-skeletal bone formation and muscle function.
A recent study found that the number of stage 3 AKI kidneys transplanted in the US has increased significantly over the last decade, yet 44% are still discarded. This highlights the need for further efforts to optimize the use of these organs and reduce waste.
Researchers at La Jolla Institute for Immunology found that macrophages in artery walls can sense octanal, leading to inflammation and atherosclerosis. By blocking this detection, they reversed disease progression. Further research is needed to explore the role of olfactory receptors in cardiovascular diseases.
Researchers have developed a new text-based analytics model that analyzes firms' tailoring of investments to their portfolio of products, using the four-stage product cycle. This framework provides insights into how firms exploit investment opportunities, including disclosure patterns and strategic alliances.
Researchers have discovered that heart disease causes early brain dysfunction, leading to reduced blood flow and increased risk of dementia. A combination of heart disease and a genetic predisposition for Alzheimer's Disease also trebles the amount of beta-amyloid protein in the brain.
Researchers at Cardiff University found that medical face masks increase facial attractiveness more than cloth masks, with blue masks being the most attractive. The study suggests that people associate masks with healthcare workers and find them reassuring, leading to a positive perception of the wearer.
Barrett's esophagus is caused by long-term GERD, which leads to changes in cells where the stomach and esophagus meet. Researchers found that stomach cells adopting intestinal cell qualities may be a key factor in its development.
Research led by Diego Bohórquez at Duke University has identified the cells responsible for sensing sugar in the gut. These neuropod cells produce neurotransmitters that transmit signals to the brain, allowing animals to distinguish between real sugar and artificial sweetener.