Articles tagged with Discovery Research
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A study suggests that smartwatch heart rate measurement algorithms are less effective in people with darker skin tones due to increased melanin absorption. Researchers emphasize the need for diverse population inclusion and explore alternative light wavelengths for more accurate readings.
A new study using subsurface imaging sheds light on the geological connection between Yellowstone's iconic hydrothermal features and deeper heat sources. The research team detected hydrothermal alteration and found a remarkable similarity in deep structure beneath areas such as Norris Geyser Basin and Lower Geyser Basin.
Researchers have identified a new family of proteins in blood vessels that prevent fluid from entering the lungs, offering a potential new avenue for treating acute respiratory distress syndrome. Stimulating these bitter taste receptors has been shown to provide protection against fluid leak into the lung.
Researchers found that suspected amygdala neurons producing corticotropin-releasing factor are not necessary for alcohol withdrawal or dependence. Instead, the CRF is believed to come from other neurons in the brain, with potential implications for human treatment options.
The American Association for Cancer Research (AACR) announced its newly elected class of Fellows of the AACR Academy, recognizing distinguished scientists who have propelled innovation and progress against cancer. The 2022 class consists of 33 luminaries from various scientific disciplines.
Researchers develop novel therapeutic approach for treating tuberculosis using phosphatase inhibitors, offering potential benefits for TB research and basic biology exploration. The discovery provides a promising alternative to traditional antibiotic-based treatments and has significant implications for combating antimicrobial resistance.
Researchers at Colorado State University have discovered that anti-malaria drugs can effectively treat a pulmonary disease similar to tuberculosis. The study found that these drugs target the bacterium's defense mechanism, preventing it from responding to stresses and reducing its ability to form biofilms.
Researchers developed a computational approach called CellTrek to combine parallel gene-expression profiling methods, creating spatial maps at single-cell resolution. The tool provides detailed information on individual cell types' location within tissues, enabling unique biological insights.
Researchers at UNLV's Nevada Extreme Conditions Lab have discovered a new form of ice with unique properties. The team found that the transition to Ice-X occurs at much lower pressures than previously thought.
A new rice rat species, possibly arboreal, was discovered in Ecuador through detailed skull analysis. The species, Mindomys kutuku, has distinct characteristics that distinguish it from its sister species.
Researchers found data analysis, accounting, cleaning, and banking to be the most boring jobs, while religion, watching TV, and bird watching were among the dullest hobbies. Stereotypically boring people are often disliked and avoided due to preconceptions, leading to social ostracization and increased loneliness.
A new research project led by Professor Edze Westra aims to uncover the mechanisms of molecular communication in viruses, which coordinate their infections and replicate in infected cells. The team will use a combination of theoretical, experimental, and observational approaches to address key questions about viral communication systems.
Researchers at the University of Huddersfield have identified a key mechanism by which the coronavirus causes inflammation in the brain's immune cells, potentially explaining some symptoms experienced by COVID-19 patients. The study suggests that adequate funding is needed to further develop this research and its potential applications.
Researchers have discovered a streamlined method for synthesizing novel neuroactive compounds found in the bark of Galbulimima trees, which may lead to new psychiatric and neurological drugs. The new approach enables easy synthesis at scale, paving the way for further study of these compounds' biological effects.
Researchers from NTU Singapore and KIMM create chemical-free printing technique to fabricate semiconductor wafers with nanowires. The method produces highly uniform and scalable wafers, leading to improved performance and high chip yield.
Intermittent fasting produces mild to moderate weight loss and improves cardiometabolic risk factors, comparable to traditional calorie-restricted diets. The review also dispels myths about intermittent fasting, including the misconception that it leads to weakness and decreased concentration.
A new study confirms that abnormalities in the GDF15 gene are involved in hyperemesis gravidarum, a condition causing severe nausea and vomiting during pregnancy. The discovery may lead to targeted treatments and improved care for women with HG.
Research found that adult howler monkey play increases when faced with competition over fruit, a valuable resource. This playful behavior helps regulate relationships within the social group and avoid conflict, unlike collective grooming used by some other primates.
Two clinical trials will report groundbreaking data on adjuvant olaparib for germline BRCA1/2 associated breast cancer and pembrolizumab for early-stage non-small cell lung cancer. These treatments aim to improve survival rates and reduce recurrence.
Researchers have designed a fast-acting injectable insulin based on the venom of the Conus kinoshitai marine snail, which doesn't form clusters like human insulin. The new hybrid insulin holds promise for better diabetes control with faster action and reduced clustering.
A research team at the Advanced Science Research Center has identified peptidoglycan as the most powerful actuator material. The new water-responsive muscles can quickly expand and contract in response to water absorption and evaporation, enabling rapid actuation of micro and macro structures.
A new virtual ligand-assisted screening method enables efficient searching of ligands for optimal catalysis, accelerating reaction design. By simplifying ligand description with two metrics, researchers identify promising ligands and focus on real testing.
A WVU postdoctoral researcher has made a groundbreaking discovery in the field of magnetic reconnection, which can be used to predict space weather events that affect satellite and power grid systems. The study uses advanced laser diagnostics to measure electron speeds, providing new insights into plasma physics processes.
Researchers from Purdue University and other institutions have discovered a supermassive black hole binary system, consisting of two black holes that orbit each other. The system is significant due to its close separation, which may lead to a merger releasing massive energy in gravitational waves.
Researchers at the University of Bath have developed a new coating method for soft robots that allows them to change shape and movement through human-controlled activity. This breakthrough in active matter could lead to the creation of machines governed by individual units that cooperate to determine movement and function.
A CHOP-led study found bortezomib significantly improved overall survival in children and young adults with newly diagnosed T-cell lymphoblastic lymphoma. The trial also showed that intensifying the chemotherapy regimen allowed for elimination of radiation in nearly all patients, resulting in excellent outcomes.
Researchers discovered that plant volatile signals can warn neighboring plants of herbivore attacks, activating defense genes and increasing resistance. The team found epigenetic mechanisms, including histone acetylation, play a key role in this process.
Researchers discovered that an inorganic polyphosphate released by nerve cells contributes to the death of motor neurons in people with ALS and frontotemporal dementia. The study found that lowering levels of this toxin may be an innovative therapeutic strategy for diverse types of ALS/FTD.
Researchers at the University of Virginia Health System have identified a potential way to treat obesity and type 2 diabetes in women by targeting a specific gene called KLF14. Increasing KLF14 abundance in fat cells may help alleviate metabolic abnormalities, including slower metabolic rates and less efficient triglyceride management.
A University of South Florida study suggests targeting kappa-opioid receptors may alleviate working memory deficits and improve executive function in individuals with severe alcohol use disorder. A compound blocking these receptors alleviated working memory deficits and restored normal executive function.
Researchers found that high levels of anti-Mullerian hormone (AMH) may cause follicles to mature too quickly, leading to problems with ovulation and fertility in women with PCOS. AMH was previously thought to be a passive byproduct of the disorder.
Aging egg cells accumulate damage to genetic material, preventing maturation and fertilization. Researchers have identified a key process causing this damage and found that anti-viral drugs can reverse it.
Researchers at Tel Aviv University have developed a unique detector using compressed xenon gas to detect axion-like particles, promising a breakthrough in finding dark matter. The new technology enables the exploration of previously inaccessible masses, constraining the properties of axion-like particles.
Researchers have demonstrated control of graphene's relaxation time, allowing for novel functionalities in devices such as light detectors and modulators. This work paves the way for the development of ultrafast optical devices with potential applications in photonics and telecommunications.
Researchers used submersibles to explore deep reefs, increasing the recorded number of deep-reef fishes by 9-fold. The study found that reef-fish faunas extend below the mesophotic zone and revealed a previously unknown reef ocean zone, the rariphotic.
A world-first discovery has identified a genetic mutation responsible for a lymphatic disorder that may cause stillbirth or severe chronic disease in affected children. The mutation, MDFIC, controls the growth and development of lymphatic vessels in the fetus, leading to fluid accumulation in critical organs.
The Precision ALS programme aims to provide new insights into Motor Neuron Disease through advanced data-driven prediction models and next-generation data analysis. The project will harness AI to analyse large amounts of data from a multimodal dataset, providing tools for clinical trials based on precision-medicine.
A new method using a thin oxide film has revealed that oxygen impurities in germanium are responsible for a surprising effect, creating holes in the material and eclipsing its semiconducting properties. This discovery has broad implications for understanding the role of thin oxide films in future semiconductor design.
Scientists have discovered a new therapeutic approach to aid the immune system in fighting cancer, offering hope for better solutions for patients. Researchers found that blocking the EP4 molecule can 'free' the immune system and restore its cancer-fighting functions.
A new study found that traditional Chinese medicine Shengmai Yin increases the sensitivity of cancer cells to radiation, reducing radioresistance. By altering DNA methylation status, SMY enhances the efficacy of radiation therapy and reduces side effects.
A Providence study confirms COVID vaccines are 94% effective at preventing hospitalization within 50-100 days of vaccination, but protection declines to 80.4% after 200-250 days. The study also identifies key risk factors for severe breakthrough infections, including advanced age, comorbidities, and vaccine type.
Researchers discovered a phase transition from charge-density-wave order to electronic nematicity in Kagome superconductor CsV3Sb5 at 35 Kelvin. This novel nematicity has Z3 symmetry, distinct from high-temperature superconductors.
Researchers at UVA Cancer Center have made a groundbreaking discovery about the EP300 gene and its role in small-cell lung cancer. The study found that the gene makes a protein with properties that can both foster and prevent tumor formation, providing a new potential target for treatment.
Researchers have found that SARS-CoV-2 variants can emerge more quickly than expected, driven by a short-lived increase in mutation rate. This phenomenon was observed in variants such as Delta, which emerged within six weeks of its ancestral form.
A new variant of the Hendra virus has been detected in Australian horses, emphasizing the need for ongoing disease surveillance. The discovery was made possible by a seven-year effort to create a network of frontline veterinarians and researchers aiming to detect new viruses.
Researchers discovered that mortars and pestles were preferred for processing rice and other plants in middle-late Neolithic China, while grinding slabs and rollers declined in use. The study provided solid evidence for the rise of mortar and pestle usage, revealing their high processing efficiency.
The 'Prize Papers' Project has made available online court documents related to the capture of approximately 1,500 ships between 1793 and 1815. Researchers can access digital copies of case books, trial records, and other materials, providing unique discoveries on global maritime history.
Researchers have created and detected dispersing excitons in a metal using angle-resolved photoemission spectroscopy, a breakthrough that could enable efficient data transmission. The discovery of mobile excitons in TaSe3 reveals their mobility and potential to revolutionize electronics.
Researchers at Arizona State University have developed a hybrid device that combines living organisms with bio batteries to produce stored energy under light conditions. The technology, known as microbial electro photosynthesis, has the potential to power a wide range of products, including transportation fuels and cosmetics.
Researchers at Gladstone Institutes have developed a novel method for identifying genetic variants that are likely to play important roles in congenital heart disease. The study leverages interactions between proteins to pinpoint candidate genes, including GLYR1, which is involved in turning other genes on and off.
Researchers have discovered a protein that plays a key role in the malaria parasite, leading to a potential new way to fight the disease. Deactivating this protein reduces the growth of the parasite by over 75%, making it a promising target for treatment development.
Scientists have discovered a new subtype of relapsed pediatric AML characterized by a specific gene mutation called UBTF exon 13 tandem duplication (UBTF-TD), which is associated with poor outcomes and an increased incidence of minimal residual disease. This mutation can be used to identify high-risk patients and guide treatment.
SMART researchers identified a novel phage lysin, Abp013, with promising antimicrobial ability against Acinetobacter baumannii and Klebsiella pneumoniae. The study demonstrated Abp013's ability to effectively target complex bacterial environments and could advance treatment methods for multidrug-resistant Gram-negative pathogens.
Researchers at Brigham and Women's Hospital discovered a new function of miR-10b, interacting with U6 snRNA to alter global splicing in glioma cells. This study highlights the potential for miRNA-based treatments in cancer therapy.
A Wayne State study reveals that communication between two key brain regions determines how we remember experiences. As these regions mature, their precise interactions improve our ability to form lasting memories. The research also found that age-related differences in fast and slow theta oscillations impact memory development.
Researchers found that epigenetic inheritance can affect the genetic composition of a population for multiple generations. Exposure to high temperatures accelerated the rate of evolution, increasing the spread of genes through mating.
A team of researchers found that many marine phytoplankton are voracious predators, consuming bacteria like Prochlorococcus and other primary production. This discovery reveals the complexity of ocean ecosystems and challenges traditional views of phytoplankton as solely photosynthetic organisms.
Researchers at the University of New Hampshire have made a groundbreaking discovery about the origin of lightning using radio telescopes. They found that the sources of lightning are indeed the streamers, or tiny spark-like discharges, supporting one of two competing theories on how lightning begins.
Researchers from Argonne National Laboratory have created a set of new practices to guide the curation of high energy physics datasets, making them more FAIR and reusable. The goal is to automate the finding and use of data for humans and streamline the development of AI tools for scientific discovery.
A research team discovered that human eggs are missing the protein KIFC1, which acts as a molecular motor to stabilize spindle poles during cell division. This finding opens up new avenues for therapeutic approaches to reduce chromosome segregation errors in human eggs.