Articles tagged with Discovery Research
Researchers found that zinc ion serves as a master-regulator of various processes in sperm to facilitate fertilization. Zinc helps maintain sperm in the non-capacitated state, preventing premature capacitation during artificial insemination.
A group of researchers discovered a new species of green algae, Gormaniella terricola, in Central New York State. The alga's unique chloroplast genome was found to contain DNA from fungi and bacteria, highlighting the importance of horizontal transfer.
Researchers at MIT identified a flawed analysis of website-fingerprinting attacks and developed new techniques to prevent them. They found that attackers can use machine-learning algorithms to decode signals leaked between software programs, enabling them to obtain private information.
A new genetic study published in Nature Genetics found that roughly one in five invasive breast cancers following ductal carcinoma in situ (DCIS) are genetically unrelated to the original DCIS. The findings provide a deeper understanding of DCIS biology and suggest that DCIS should be considered a risk factor for the development of inv...
Researchers have created a new electrical test to screen hundreds of gene mutations, pinpointing harmful mutations that cause inherited heart disorders and sudden death. The breakthrough can identify genetic variants associated with neurological conditions, muscle and kidney diseases.
Scientists have discovered a new molecule, ERX-41, that effectively targets and kills cancer cells with elevated endoplasmic reticulum stress. The compound exploits the weakness in cells not previously targeted by other drugs, showing promise for patients with triple-negative breast cancer and other hard-to-treat cancers.
Researchers discovered Zophobas morio 'superworms' can survive on polystyrene diet, suggesting they can derive energy from it. The worms' gut microbes are believed to play a crucial role in breaking down the plastic material.
The Gloucester, a warship that sank in 1682 while carrying James Stuart, has been discovered off the Norfolk coast. The wreck is significant due to its age and political context, offering insights into 17th-century social, maritime, and political history.
Researchers will track changes in the blood-brain barrier, neurovascular function, and cognition in over 850 participants with genetic variants at risk of developing Alzheimer’s disease. The study aims to improve understanding of the onset and progression of Alzheimer’s disease and identify effective interventions.
Researchers at Karolinska Institutet have developed nano-sensors that can detect pesticide residues on fruit surfaces in just five minutes. The sensors use flame-sprayed nanoparticles made from silver to increase the signal of chemicals, overcoming high production costs and limited batch-to-batch reproducibility.
Researchers have identified glycans in mucus that can prevent Candida albicans from causing infection. These molecules can be used to develop new antifungal medicines or make disease-causing fungus more susceptible to existing drugs.
Researchers at the Beckman Institute for Advanced Science and Technology observed structural chirality in achiral conjugated polymers, which can enhance solar cells' charge capacity. This discovery introduces new opportunities for research at the convergence of biology and electronics.
The INCLUDE Data Hub provides centralized access to large-scale research resources, including biospecimen libraries and clinical datasets, for the study of Down syndrome. With over 8,000 study participants and 30,000 biospecimens, researchers can accelerate discoveries that benefit people with Down syndrome.
Researchers used drone data to analyze vegetation indicators, such as color appearances, to predict southern rust outbreaks. The study revealed a positive correlation between the presence of southern rust at grain-filling time and yield, enabling informed decision making for growers.
Researchers have identified an anti-malarial compound, ML901, that inhibits the malaria parasite without harming mammalian cells. The compound works by hijacking a reaction to make the parasite self-destruct, showing rapid and prolonged action against resistant strains.
Researchers developed a methodological framework to ensure web data validity in marketing studies. The study provides recommendations for addressing challenges in collecting and using web data via web scraping and APIs.
A team of researchers has found a way to block the replication of one strain of the influenza virus in human cells by inhibiting a specific protein modification process called SUMOylation. This breakthrough could lead to highly effective treatments for the flu and other respiratory viruses.
Scientists at Scripps Research discovered a genetic mutation in PIEZO1 ion channel that impacts tendon biology and boosts the physical performance of mice. Mice with the PIEZO1 mutation had wider tendons, more compliant structures, and could store three times more energy.
A new study reveals that Manx shearwaters use dynamic soaring to harvest wind energy and travel efficiently across the ocean. The birds' ability to adapt their flight patterns to optimize energy gain suggests a potentially game-changing strategy for drones and other aerial vehicles.
A SUTD study has uncovered the reservoir filling strategies and operating rules of China's big hydropower dams on the Lancang-Mekong river. The data shows that dam operations remained steady during a severe drought, indicating no need for emergency releases to mitigate its impact.
This study shows how specific brain regions control the immune response during acute stress, highlighting the detrimental effect on fighting off infection. Researchers found that acute stress prompts a major migration of immune cells, diminishing an immune response to viruses like COVID-19 and influenza.
Researchers found that severe asthma patients produce growth factors that block corticosteroids from working, leading to frequent breathing problems. This discovery may lead to new treatments targeting these growth factors to improve outcomes for patients with severe asthma.
The Frontier supercomputer has achieved an unprecedented level of computing performance, breaking the exascale barrier with 1.1 exaflops of performance. This milestone enables scientists to tackle previously unsolvable problems in fields like energy and national security.
Researchers at Georgia State University have been awarded over $6 million to develop antiviral drugs targeting COVID-19 and other viral threats. The funding will support the establishment of a new Midwest Antiviral Drug Discovery Center, which aims to build a pipeline of antiviral drugs.
Recent studies from Cedars-Sinai have shed light on the importance of a gene in embryo development and its potential link to physical abnormalities. Additionally, research has shown that getting vaccinated against Covid-19 can strengthen immune responses in patients with inflammatory bowel disease. The institution is also working on ne...
Virginia Tech scientists led by Sora Shin are investigating the brain pathways responsible for high-fat diet overconsumption. The study aims to identify a framework for understanding how leptin-responsive circuits respond to food exposure and increase the risk of emotional overeating after abstinence.
The University of Louisville is launching a new campus to focus on health as a shared community resource, incorporating environmental and cultural factors. Researchers will engage with the community to discover how natural environments impact health.
Researchers uncovered intricate settlements in Bolivia's Llanos de Mojos savannah-forest, featuring elaborate structures and a vast network of reservoirs. The cities were built alongside nature, employing successful sustainable subsistence strategies that promoted conservationism and maintained rich biodiversity.
Researchers are utilizing UAVs to capture real-time images of rice crops, extract crop phenotypic traits from the images, and analyze that information to discover superior, high-yielding rice genotypes. The team aims to develop automated algorithms to identify key traits and select best-performing rice genotypes.
Australian researchers have discovered specific gene networks rewired to drive peanut allergy remission through a combination treatment of probiotic and oral immunotherapy. This network reprogramming shuts down the allergic immune response responsible for causing food allergies.
Research reveals pridopidine enhances autophagy in ALS model, reducing toxic protein aggregation and promoting neuronal health. The study supports pridopidine's potential as a treatment for neurodegenerative diseases like Huntington's disease and Alzheimer's.
Researchers discovered a specific glycoprotein, RPTP zeta S3L, that connects to CD33 receptors in the brain, limiting its ability to clean up harmful proteins. This finding may lead to new drug targets and early diagnostics for Alzheimer's disease.
A new study by USC researchers found a significant link between exposure to fine particles (PM2.5) and nitrogen dioxide (NO2) and increased risk of severe COVID-19 outcomes. Long-term PM2.5 exposure was associated with a higher risk of mortality from COVID-19.
The Mount Sinai Hospital will recruit eight postdoctoral trainees for a five-year fellowship program in emergency care research. The program aims to investigate complex medical questions and lead to studies transforming patient care.
A recent study published in JACC: Advances has discovered a significant correlation between the racial demographics of cardiovascular disease fellowship programs and the race of their program directors. The study, led by Indiana University researcher Ankur Kalra, found that fellows from diverse backgrounds are more likely to be accepte...
A study led by Tel Aviv University researchers reveals a common mechanism underlying genetic mutations associated with autism, schizophrenia, and other neurological disorders. The discovery points to an experimental drug developed by the team as a potential treatment for these conditions.
A landmark research article published in Science predicted exponential growth in US drug overdose deaths, which has now come true with over 100,000 annual deaths. The Pitt team suggests that a systems analysis and computational models are necessary to understand the deep causal drivers of the epidemic.
The BiCIKL Project has successfully integrated FAIR data on biodiversity for a year, focusing on creating a more transparent and efficient research ecosystem. The project aims to link different sources of biodiversity data across various infrastructures and open data platforms.
Researchers at the University of Virginia Health System have made important discoveries on the crucial role of malnutrition in global tuberculosis, highlighting how gut infections impair treatment outcomes. A new funding partnership will train Tanzanian postdoctoral researchers to work specifically on this intersection.
Research team from Goethe University reproduces Asian monsoon conditions in experimental chamber, identifying increased aerosol particle formation. The study found that ice clouds can form under lower water vapour supersaturation than anticipated, affecting climate models' accuracy.
A team of scientists discovered that over half of known 3D materials in nature exhibit at least one topological state, challenging the long-held idea that these materials are rare. The study also introduces a new concept called 'supertopological' and makes its data freely available to researchers.
Researchers have discovered that 90% of known crystalline structures contain at least one topological property, and more than 50% exhibit some sort of topological behavior. The newly identified materials are stored in a freely accessible database, allowing scientists to quickly search for materials with robust electronic properties.
Researchers at Institute of Physics Chinese Academy have discovered new zirconium polyhydrides that exhibit superconductivity with a high transition temperature (Tc) of ~71 K. The compounds can be synthesized under high pressure conditions and may lead to the discovery of new superconducting materials.
Researchers from Edith Cowan University, CSIRO, and WEHI have decoded the genome of oats, revealing why they may be a suitable alternative to wheat for those with coeliac disease. The study found that oats contain fewer gluten-like proteins, making them a potentially healthier option.
A study published in Nature Communications sheds light on dopamine transporter (DAT) function, which regulates brain reward centre communication. The researchers discovered DAT depends on potassium, not just sodium, rewriting textbooks on its mechanism.
A new study published in PNAS reveals that a specific bacterial compound, lipopolysaccharide, induces larval marine tubeworms to settle on the seafloor and undergo metamorphosis. The discovery offers hope for coral reef restoration, mariculture, and biofouling prevention.
The discovery of a 164,000- to 131,000-year-old Denisovan tooth in Laos provides significant insights into the species' geographic range. The ancient tooth's shape and similarity to teeth found on the Tibetan Plateau suggest that Denisovans inhabited Southeast Asia, particularly northern Laos.
Researchers at the Beckman Institute found a direct link between high-fat diets and heightened nitric oxide levels, which can lead to increased risk of inflammation and cancer development. The study used a molecular probe to visualize changes in the tumor microenvironment.
A new screening tool has been developed to identify pregnant women at risk of eating disorders, allowing for early intervention and treatment. The Prenatal Eating Behaviors Screening (PEBS) tool, created by WVU researchers, uses a 12-question screener to assess symptoms and emotions associated with eating disorders.
A new species of Phalotris snake was discovered in Paraguay's Cerrado forests, characterized by its unique red head, yellow collar, and black lateral band. The species is considered Endangered due to its extreme rarity and limited distribution.
A team led by Flinders University archaeologist Dr Martin Polkinghorne is reuniting ancient ceramics with their ships of origin, developing a narrative of ancient global trade. The research project will also promote cultural value and awareness among communities in Indonesia and Australia.
Researchers at the University of Colorado School of Medicine have found that histone deacetylase 6 (HDAC6) regulates heart stiffness by acting on titin protein. This discovery could lead to novel treatments for heart failure, a condition affecting millions worldwide.
Two new species of Amazonian fish have been discovered and described by Smithsonian researcher Murilo Pastana, one with vibrant red-orange fins and another that is technically a miniature fish. The species are at risk of extinction due to deforestation in the region where they inhabit.
Plazi receives EUR 1.5 million grant from Arcadia Fund to develop Biodiversity Literature Repository (BLR), providing access to over 750,000 taxonomic treatments, figures, and material citations. The project aims to liberate data from scientific publications, making it FAIR and open for researchers.
A Kyoto University study has discovered that c-type natriuretic peptide facilitates intracellular calcium signaling in chondrocytes to stimulate long bone growth. This finding may lead to the development of new bone growth-stimulating agents for treating developmental disorders.
Researchers at Johns Hopkins Medicine have designed nanobodies derived from llama antibodies to target specific sodium ion channels in human muscle cells. This breakthrough could lead to safer and more efficient treatments for pain during surgery and irregular heart rhythms, as well as seizure control.
Researchers suggest a novel neuroimaging technique can unveil Alzheimer's disease secrets and predict symptom risk. The 'neuromelanin-sensitive MRI' method provides insights into the brain's noradrenergic system, linked to aggressive behavior and cognitive decline.
Private companies like GlaxoSmithKline and Imperial College London have carried out high-risk breaches, handling sensitive patient data outside of agreed contracts. NHS Digital's audits show that many organisations have failed to protect patient confidentiality, with no consequences for those who breach agreements.
Researchers revived photoreceptor cells in human macula, responding to bright and dim lights. The study restores communication between retinal cells, transforming brain and vision research.
Researchers from Clemson University have discovered a promising therapy for toxoplasmosis, a disease caused by the microscopic protozoa Toxoplasma gondii. The team has enlisted an unlikely ally - the herbicide oxadiazon - in the fight against the single-celled parasite.