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SP-101 is a novel AAV gene therapy for cystic fibrosis

Scientists from Spirovant Sciences describe a novel adeno-associated virus (AAV) gene therapy called SP-101 that has been optimized for efficient human airway cell transduction. After single dose inhaled delivery, the vector showed consistent expression of a functional and regulated shortened human CFTR minigene.

Sky-Watcher EQ6-R Pro Equatorial Mount

Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.

RNA template-based targeted gene editing in mammalian cells

Experts propose a series of scientific principles and experimental approaches to assess potential carcinogenicity of gene therapies. Data transparency is crucial, with publicly accessible data from viral integrations site studies and clinical settings.

Is it time to redefine youth sport participation?

Researchers propose a new model to understand youth sport participation, mapping out seven phases of involvement. The 'Participation Re-Engagement (PRE) Model' aims to encourage retention and re-engagement efforts, recognizing opportunities for young people to participate in sports.

Changing food consumers' choices may help cut greenhouse gases

Researchers found that adopting plant-based diets could reduce greenhouse gas emissions from food supply chains by 17%, saving 32.4% of global dietary emissions. This would balance the increase in emissions from under-consumed populations moving towards healthier diets.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Japan’s youth and climate change

A recent study reveals that Japanese junior high school students can be divided into four groups: Apathetic, Confused, Concerned, and Advocate. The most important factors influencing engagement in climate change actions are feelings of concern, hope, and attitude towards finding solutions. The research emphasizes the importance of emot...

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Subretinal AAV T-cell Inhibition

Researchers found that subretinal adeno-associated virus 8 injections trigger proinflammatory T-cell responses, but co-injection of immunodominant peptides can modulate the immune system. This study suggests a new approach to AAV gene therapy for retinal diseases.

AAV vectors trigger innate immune pathways

Researchers describe redundant innate immune pathways triggered by AAV vectors, including sensing of viral genome and cytoplasmic DNA sensors. The study highlights the need to understand complex biologic mechanisms underlying adverse reactions to AAV vectors in human gene therapy trials.

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

British conversation is changing: Why people speak more alike today

Research by Lancaster University found that people in higher social grades, including corporate world and education sectors, are adopting each other's speech patterns to be more inclusive. This 'resonance' has increased over the past 20 years, particularly among those with high social status.

Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Violence, aggression against educators grew post-pandemic

After a pandemic-induced lull in violence, incidents rebounded to pre-pandemic levels, causing 57% of teachers to consider resigning or transferring. The study highlights a growing crisis that requires comprehensive approaches to address violence and build positive schools.

Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

Significant gaps between science of obesity and the care patients receive

A new American Heart Association scientific statement reveals significant gaps in the application of obesity research to patient care, with widespread adoption varying by healthcare professional and institution. The statement emphasizes the need for better implementation of evidence-based treatments and strategies, such as lifestyle mo...

The number of people experiencing poor health and early death caused by metabolism-related risk factors such as high blood pressure, high blood sugar, and high BMI has increased by 50% since 2000, reveals new global study

The Global Burden of Diseases study reveals a 49.4% increase in global disability-adjusted life years (DALYs) attributable to metabolism-related risk factors between 2000 and 2021. High blood pressure, high blood sugar, and high BMI are key contributors to poor health and early death.

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

Women in facial plastic and reconstructive surgery

A new study reveals that women make up just 13% of the American Academy of Facial Plastic and Reconstructive Surgery membership. The authors highlight the need for education, mentorship, and sponsorship to address these disparities and promote a more inclusive future for female surgeons.

Social media use linked to tobacco initiation among youth

A new study published in Addictive Behaviors found that frequent social media use among US youth is associated with a higher risk of tobacco initiation. Youth who engaged with tobacco marketing on social media platforms were more likely to start using tobacco products, highlighting the need for regulation and education.

CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Research reveals tools to make STEM degrees more affordable

A new study explores ways to reduce student loan debt and increase affordability in STEM fields, finding differential tuition and policy gaps hinder efforts. Experts advocate for tuition caps, state subsidies, and ongoing conversations to remove barriers to STEM education and careers.

Discovery of a marker of delayed recovery of concussion in children

A new study has identified alpha-1-antichymotrypsin as a blood protein marker that can predict delayed recovery of concussion in children. The study found that children with low levels of alpha-1-antichymotrypsin were more likely to experience delayed recovery, highlighting the potential for early diagnosis and targeted treatment.

Sony Alpha a7 IV (Body Only)

Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.

Promoting healthy movement behaviors in children under five in Europe

The SUNRISE European Study Group urges European countries to take specific actions to promote healthy movement behaviors in children under five years. Effective policies targeting upstream environmental influences are required to equitably change movement behaviors among European populations.

WVU spearheading regional USDA project to increase agricultural production

The WVU Institute for Community and Rural Health is leading a five-year, $8.5 million cooperative agreement grant to support underserved farmers in West Virginia, Pennsylvania, Virginia, and North Carolina. The project aims to increase agricultural production, provide working capital, and create farm-to-institution markets.

Alcohol raises heart disease risk, particularly among women

A large study found that drinking more than one drink per day can increase the risk of coronary heart disease, especially among young to middle-aged women. The risk was highest among those who engaged in binge drinking, with women facing a 68% higher risk compared to moderate drinkers.

Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Is it the school, or the students?

A recent study by MIT scholars reveals that widely disseminated school quality ratings are heavily dependent on the preparation and family background of their students. The study finds that many schools with low ratings perform better than expected, and conventional ratings are highly correlated with race.

Nikon Monarch 5 8x42 Binoculars

Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

Active social lives help dementia patients, caregivers thrive

People with dementia experience declines in social well-being as their disease progresses, while caregivers become isolated due to caregiving responsibilities. Experts recommend screening for loneliness and finding ways to keep individuals socially connected to improve quality of life and reduce health outcomes.

Study tracks shifts in student mental health during college

A four-year study by Dartmouth researchers tracks changes in student mental health during college, identifying key populations and stressors. The study found that first-year and female students are at risk for high anxiety and low self-esteem, while sophomores experience increased social activity but higher stress levels.

Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Apple AirPods Pro (2nd Generation, USB-C)

Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

How Americans really feel about the teaching of controversial topics in schools

A new USC study found that Americans are united on core principles of public education, but diverge on sensitive topics like LGBTQ+ inclusion and racial justice in K-12 curricula. The survey revealed deep partisan divides, with Democrats generally supporting teaching controversial topics, while Republicans were less supportive.

Telehealth is as safe as a visit to the clinic for abortion pills

A large national study of over 6,000 patients found that video visits, texting and mailing pills were effective and safe for medication abortion. The research supports the safety and efficacy of telemedicine abortion, which has become increasingly important due to clinic closures and wait times.

GoPro HERO13 Black

GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.

Garmin GPSMAP 67i with inReach

Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.

Are body temperature and depression linked? Science says, yes

Researchers found a correlation between body temperature and depression symptom severity in a large international study. Participants with higher depression scores had higher body temperatures, suggesting that cooling the body may be a novel treatment approach for depression.