Psychiatry
Articles tagged with Psychiatry
Refugees reveal hidden trauma of life in the UK
Bidirectional association between premenstrual disorders and psychiatric disorders
Doctors favor explaining anxiety to patients as a human evolution ‘success story’
A new study found that mental health clinicians prefer evolutionary explanations of anxiety over genetic approaches, believing they provide a more positive outlook and can improve patient willingness to seek help. This shift could lead to more hopeful and therapeutically empowering attitudes towards anxiety treatment.
Genotype-guided antidepressant prescribing for patients with depression
A randomized clinical trial found that genotype-guided prescribing of SSRIs did not improve depression symptoms at 3 months but showed higher remission rates at 6 months. Future studies should focus on the long-term impact of this approach.
Ketamine infusions and rapid reduction of suicidal and depressive symptoms in major depressive episode
A systematic review and meta-analysis found single and repeated intravenous ketamine infusions to be efficacious in reducing suicidal and depressive symptoms in acute major depressive episodes. Longer-term outcomes remain unclear.
Adjunctive antipsychotics in major depressive disorder
This systematic review and meta-analysis found differences in efficacy and acceptability of adjunctive atypical antipsychotics for major depressive disorder. The study highlights the need for more well-controlled studies on maintenance efficacy of these medications.
Brain Health emergency: Microplastic burden in the human brain now linked to stroke and dementia, with apheresis emerging as the first plausible removal pathway
A study finds microplastics in the human brain associated with increased risk of stroke and dementia. Apheresis, a medical treatment, is proposed as a potential removal method for microplastics from the body.
The boy on the balcony who never came outside
Dr. Dilek Colak's journey began with a childhood observation of a boy with mental illness, which inspired her to pursue a career in neuroscience. Her current work focuses on understanding autism and schizophrenia through the study of human brain organoids.
May 2026 issues of APA journals feature new research on PTSD, substance use disorders, psychopharmacologic treatments, and more
The latest issues of APA journals feature new research on PTSD and substance use disorders. The American Journal of Psychiatry explores the understanding of these conditions, while Psychiatric Services discusses the future of the DSM. Focus journal delves into psychopharmacologic treatments with expert perspectives.
Severe narcolepsy found to damage a second brain region
Researchers found significant loss of neurons in the locus coeruleus, a second critical region involved in arousal and muscle tone regulation. This finding suggests an immune-mediated process and challenges the prevailing explanation for narcolepsy with cataplexy.
The link between reduced inpatient care and suicide
A nationwide ecological study found a statistical correlation between fewer psychiatric beds and higher suicide rates in Sweden. The study suggests that investing in outpatient care may not be enough to prevent suicides, highlighting the need for further research into healthcare resource allocation.
TBI survivors turn to psychedelics for symptom relief
A new study found that nearly 1,200 TBI respondents used psychedelics to treat or manage physical health conditions, with 208 participants using them to manage brain injury-related symptoms. Researchers reported a 90% self-reported symptom improvement rate.
Can wearable technology detect the earliest signs of autism in infants? New study seeks to find out
Researchers are developing a new wearable technology to monitor babies' movements and detect early signs of autism. The study aims to improve early identification and intervention, which is crucial for optimal developmental outcomes in autistic individuals.
Under embargo: Families and friends speak out on electroconvulsive therapy’s silenced risks
A new study reveals that electroconvulsive therapy (ECT) can lead to significant negative impacts on standard of living, personal relationships, and even brain damage. Relatives and friends of ECT patients report long-term effects including memory loss, emotional blunting, and loss of independence.
How do patients’ relatives and friends view the benefits and harms of electroconvulsive therapy?
A survey of 286 relatives and friends found that 45% experienced improvement, while 42% saw worsening symptoms. Many reported memory loss, difficulty concentrating, and relationship problems after ECT.
Preschool children born with heart defects have greater risk of developing behavioral problems
A recent study published in Frontiers in Pediatrics has found that preschool children born with heart defects are at a greater risk of developing behavioral problems, including ADHD and peer relationship issues. The study suggests that a cognitively stimulating home environment may help reduce this risk.
Bullying and adverse social climate take measurable toll on mental health of gender-diverse youth
Research found that gender-diverse teens reported higher rates of psychological stress and psychotic-like experiences, which can lead to depression, anxiety, and other serious mental health disorders. Bullying and unsupportive legislation drove these findings.
JMIR report: Why mental health tech needs systems, not just tools
The report highlights a critical implementation gap in digital mental health tools, which struggle to reach the masses due to inadequate infrastructure. The industry has excelled in creating evidence-based tools and AI systems, but fails to deliver them at population scale without proper systems in place.
Age at first ADHD diagnosis and educational outcomes
A cohort study found that individuals diagnosed with ADHD at a younger age tended to perform better academically, receiving more education and experiencing lower dropout rates compared to those diagnosed closer to age 16. This suggests that targeted support for early diagnoses could help prevent school dropout.
AI can describe human experiences but lacks experience in an actual ‘body.’ UCLA researchers say understanding this ‘body gap’ may matter for safety
Current AI systems lack internal embodiment, a property that humans take for granted, which can lead to performance and behavior limitations. Researchers propose a dual-embodiment framework to guide future research in building safer and more aligned AI models.
Mirtazapine for methamphetamine use disorder
In this randomized clinical trial, mirtazapine effectively reduced methamphetamine use in adults with methamphetamine use disorder. The study's findings have important implications for the treatment of this condition, which currently lacks approved pharmacotherapies.
When the nervous system starves the brain: Autonomic dysfunction unmasked as a hidden driver of treatment-resistant depression
A study published in Brain Medicine suggests autonomic dysfunction, particularly parasympathetic and sympathetic imbalances, contributes to depressive symptoms in patients unresponsive to conventional antidepressants. Low-dose medications targeting these imbalances may offer a new approach to treatment.
Toward strategies for extending ketamine’s antidepressant effects
Researchers identified NOX-1 as a key molecular target to prolong ketamine's therapeutic benefits. Combining ketamine with NOX-1 inhibitors significantly extended its antidepressant-like effects. K-4, a novel AMPAR modulator, also showed rapid antidepressant effects that persisted for at least 2 weeks.
Fathers’ mental health deteriorates long after the birth of their child
A new study published in JAMA Network Open reveals that fathers' mental health declines over time after the birth of their child, with increased risk of anxiety and substance abuse diagnoses returning to pre-pregnancy levels. However, depression and stress-related disorders continue to rise by over 30% one year after childbirth.
European Psychiatric Association rolls out landmark action plan to modernize care and protect vulnerable mental health communities across Europe
The European Psychiatric Association has launched an action plan to address unmet needs in psychiatric care, focusing on brain health, treatment delivery, stigma reduction, and preventive measures. The plan aims to improve diagnostic accuracy and precision care through its 80,000-psychiatrist network.
Housing displacement, employment disruption, and mental health after the 2023 Maui wildfires
The study found that wildfire exposure and its socioeconomic consequences were associated with increased psychological distress beyond the burn zone. Integrating mental health care, housing stability, and economic recovery are crucial for disaster response and climate resilience strategies.
A comprehensive review charts how psychiatry could finally diagnose what it actually treats
Emerging research across conceptual frameworks, biomarker science, digital phenotyping, and artificial intelligence synthesizes a translational pathway toward a more biologically grounded and clinically useful approach to psychiatric diagnosis. The current system falls short due to standardized clinical language and lack of biological ...
Growth in telemedicine has not improved mental health care access in rural areas, study finds
A new study by Brown University and Harvard Medical School found that telemedicine does not substantially increase access to mental health care for those in rural or underserved areas. Despite its convenience benefits for existing patients, telemedicine did not lead to a significant expansion of care access for these populations.
Genetic risk for mental illness is far less disorder-specific than clinicians have assumed, massive Swedish study reveals
A massive Swedish study of over 2 million individuals reveals that genetic risk for mental illness is far less disorder-specific than clinicians have assumed. Schizophrenia shows the highest genetic specificity, while drug use disorder has a much lower specificity, scattering its genetic risk across multiple conditions.
Ultra-processed foods in preschool years associated with behavioural difficulties in childhood
Researchers at the University of Toronto found that higher ultra-processed food consumption is associated with increased anxiety, fearfulness, aggression and hyperactivity in preschoolers. Replacing ultra-processed foods with minimally processed options may support healthier development and lower behavioural difficulties.
March 2026 issues of APA journals feature new research on bipolar disorder treatment, prevention of PTSD symptoms, access to eating disorder care, and more
The latest American Psychiatric Association journals feature new research on treating bipolar disorder, preventing PTSD symptoms, improving access to eating disorder care, and more. Journal highlights include advancements in schizophrenia treatment and a retrospective analysis of suicide deaths in U.S. immigration detention.
Benzodiazepine use declines across the U.S., led by reductions in older adults
Benzodiazepine use decreased across the US from 2018 to 2022, with the greatest decline among older adults. Nearly half of patients receiving benzodiazepines also took other central nervous system depressants, increasing the risk of adverse effects.
Dysregulation of the immune system differentiates depression and psychosis in young adulthood
A study found distinct inflammatory biomarkers and brain signatures for early-stage depression and psychosis, differing even in the earliest stages. These findings support customized therapies and may reduce risk of severe progression.
University of Houston professor warns of nerve stimulation during MRI
Researchers found that implanted cuff electrodes can trigger unintended nerve stimulation during MRI, causing discomfort or pain. The study recommends more refined guidelines and careful safety considerations to mitigate this risk.
Online searches for crisis hotlines surged worldwide and rise in the same months as suicide-related searches
A new study analyzing global Google Trends data reveals a sharp increase in online searches for crisis hotlines, particularly in recent years. The findings suggest that digital help-seeking signals can provide timely insight into population distress and demand for crisis resources.
Can the mental health benefits of exercise be bottled?
Exercise mimetics aim to replicate the muscle-brain axis benefits of physical activity without requiring engagement in regular exercise. By activating key molecular pathways, these compounds may alleviate depressive symptoms without traditional therapy or medication.
Spirituality and harmful or hazardous alcohol and other drug use
A meta-analysis of 55 studies found a significant protective association between spirituality and hazardous alcohol and drug use. The study suggests that spiritual practices may be effective in preventing or reducing the risks associated with these substances.
1 in 6 Medicare beneficiaries depend on telehealth for key medical care
A cross-sectional analysis found that nearly half of mental health visits and 29 million non-mental health telehealth visits occurred annually. The study suggests that telehealth has become an essential component of care for older and medically vulnerable adults, raising concerns about rolling back telehealth flexibilities.
SSRI medication during pregnancy is associated with increased risk of gestational diabetes but may protect against preterm birth
Research finds that SSRIs during pregnancy increase gestational diabetes risk in newborns but lower preterm birth and low birth weight risks. SSRIs also associated with breathing problems and neonatal care needs in newborns.
New resource supports trauma survivors, health professionals
A new online tool provides information and tools for clinicians to respond to emerging patient care needs, enhancing trauma-informed healthcare for individuals with C-PTSD. The resource was co-developed by researchers and survivors, aligning with best practices and patient-centered research.
Brief, intensive exercise helps patients with panic disorder more than standard care
Researchers discovered that brief intermittent intense exercise is a more effective treatment for panic disorder than relaxation therapy. The 12-week program showed significant reductions in Panic and Agoraphobia Scale scores, anxiety, depression, and panic attack frequency and severity.
Maternal perinatal depression may increase the risk of autistic-related traits in girls
A large-scale Japanese cohort study and mouse experiments reveal that maternal perinatal depression increases autistic-related traits in toddlers, with a particularly strong impact on girls. The findings suggest a sex-specific neurobiological pathway underlying these effects.
Weill Cornell physician-scientists recognized with ASCI early-career awards
Two Weill Cornell physician-scientists, Dr. Semra Etyemez and Dr. Jesse Platt, have been awarded prestigious early-career awards from the American Society for Clinical Investigation (ASCI) for their outstanding research in obstetrics and gynecology, psychiatry, and gastroenterology. The ASCI recognizes and supports the scientific effor...
A ketogenic diet for treatment-resistant depression
A ketogenic diet was found to have a modest effect in reducing depressive symptoms in patients with treatment-resistant depression. The study's results suggest that this dietary approach may be worth exploring as an adjunct therapy option.
Mental health crisis: Global surveys expose who falls through the cracks and how to catch them
Dr. Ronald C. Kessler's decades-long research transformed international understanding of psychiatric disorders and suicide prevention. His work exposes the global scope of mental health challenges and highlights key factors in prevention.
More Ontarians are being diagnosed with psychosis than those born in earlier decades
A new study found a significant increase in psychotic disorders among Ontarians born after 1980, with incidence rates rising by 60% for those aged 14-20. The study suggests that recent birth cohorts may be experiencing increased exposure to risk factors such as early life substance use and older-aged parents.
Worrying rise in self-harm among adolescents, with trans, gender diverse and early school leavers most at risk
Research found that rates of poor mental health and suicide attempts have largely recovered, but repeated self-harm is increasing, especially among females. Trans and gender-diverse young people and early school leavers are particularly vulnerable to mental distress.
How bacteria in the mouth may offer new clues to cognitive dysfunction in people with schizophrenia
Research suggests that lower oral microbiota diversity is associated with poorer cognitive function in people with schizophrenia. The study also identified specific microbial metabolic pathways potentially linked to this relationship.
Breakthrough study reveals early neural circuit that determines food reward
Researchers at the University of Delaware discovered a neural network in fruit fly brains that assigns value to specific foods minute by minute, integrating context, internal state, and past experience. This breakthrough study offers insights into the origins of eating disorders and addiction.
More than just ‘daydreaming’ – dissociation is the mind’s survival tactic
Dissociation is a complex survival mechanism in response to overwhelming trauma, affecting memory, identity, and perception. Research confirms its prevalence among individuals who have experienced trauma, and effective dissociation-specific treatment options are needed.
UH psychologist explores reducing anxiety among survivors of sexual assault
A UH psychologist's study finds that anxiety sensitivity and pain-related anxiety are linked to mental health problems and clinically significant alcohol use among survivors of traumatic sexual assault. The investigation highlights the importance of addressing both types of anxiety in reducing the risk of lifelong challenges.
Identification of the central pathological substrate of bipolar disorder as paraventricular thalamic nucleus
The study reveals that the paraventricular thalamic nucleus (PVT) is the central pathological substrate of bipolar disorder, with notable alterations in cell number and gene expression. This discovery highlights the PVT as a potential diagnostic and therapeutic target for improving patient outcomes.
Tailored treatment approach shows promise for reducing suicide and self-harm risk in teens and young adults
A new study demonstrates a health care approach matching treatment intensity to individual risk levels can significantly reduce self-harm and depression among at-risk adolescents and young adults. The randomized clinical trial found significant reductions in self-harm behaviors, improved patient satisfaction, and high follow-up rates.
Decades of suffering: Long-term mental health outcomes of Kurdish chemical gas attacks
A study of over 500 survivors found severe psychological trauma with somatic symptoms persisting decades after the attack. The results highlight the need for culturally sensitive mental health services, compensation, and ongoing care for chemical attack survivors.
Ambitious model fails to explain near-death experiences, experts say
UVA experts Bruce Greyson and Marieta Pehlivanova argue that the NEPTUNE model leaves many unanswered questions about near-death experiences. Despite its sophistication, the model selectively ignores scientific evidence and fails to address key aspects of NDEs.
Where are the biomarkers in psychiatry? Psychiatrists take first steps towards establishing a structure for objective mental health diagnosis
Researchers are creating a centralized database to standardize and share biomarker research in anxiety disorders, depression, and psychosis. This initiative aims to advance precision psychiatry by integrating biological, behavioral, and clinical data for more accurate diagnosis and treatment.
Asthma-related depression may be biologically distinct from primary depression
Adults with asthma who experience depressive symptoms have elevated blood levels of brain-derived neurotrophic factor (BDNF), a protein typically reduced in major depressive disorder. Physical activity may also play a role in depression management, as lower activity levels are linked to worse moods.
With telehealth coverage on the brink, study shows it hasn’t driven up total visits
A recent University of Michigan study analyzed over 60 million Medicare participants and found that total visits remained stable or declined slightly through June 2024. Despite widespread adoption of telehealth, overall healthcare visits stayed steady or decreased, contradicting predictions of increased utilization.
Common: being wrong. Less common: admitting it
Researchers at the University of Houston found that admitting intellectual errors can increase public trust in science. In a classroom setting, professors who admit mistakes were rated higher by students for warmth, competence, and teacher effectiveness. This study highlights the importance of intellectual humility in building respect.