A specific group of neurons in the amygdala has been identified as a key player in anxiety, depression, and altered social behavior. Restoring balance to this area can reverse these behaviors in mice.
Researchers used advanced neuroimaging and the Julich-Brain Atlas to identify specific brain networks linked to psychopathy, finding reduced volumes in multiple regions including basal ganglia, thalamus, and cortex. This study advances research on neuropsychobiological correlates of aggression.
Research found that ADHD medication was associated with lower risks of self-harm, unintentional injury, and crime, but the magnitude of these associations decreased as prescription rates rose. The study highlights the need to regularly assess medication use in different patient populations.
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JMIR Publications' portfolio of journals now includes 21 titles with a Journal Impact Factor. Several journals saw significant increases in impact factor, including JMIR Medical Education, which debuted with a score of 12.5, securing the top-ranked journal spot in its category.
A new international study identified two distinct genetic signatures for complex forms of Alzheimer's disease, with one primarily driven by apolipoprotein E and the other involving a combination of 75 additional genetic variants. This shared biological mechanism is largely consistent across global populations.
The Supreme Court's decision increases the likelihood of states limiting or eliminating family access to medical care. Medical professionals emphasize the need for individualized assessments and patient-centered care.
A study of 7,944 ADHD patients found that telehealth-based relationships did not increase the risk of substance use disorder. However, patients aged 26 and above who received initial stimulant prescriptions during telehealth appointments were at higher risk.
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Dr. John Oldham's contributions have fundamentally reshaped personality disorder classification, moving from rigid categories to a more nuanced dimensional system. His Alternative DSM-5 Model for Personality Disorders (AMPD) has marked the most significant epistemological shift in psychiatric diagnosis for decades.
Sara Poletti's research reveals how childhood trauma triggers persistent neuroinflammation pathways and alters brain structure, creating lifelong vulnerability to psychiatric disorders. Her work identifies biological markers of trauma and explores prevention strategies to reduce mental illness odds.
Researchers at the University of Houston found that females with more psychologically flexible personalities have fewer signs of eating disorders. The study suggests a personalized approach to therapy may be most effective for preventing eating disorders when using Acceptance and Commitment Therapy.
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Dr. Enrico Castillo, an assistant professor of psychiatry at UCLA, has been recognized as an emerging leader in health and medicine scholar by the National Academy of Medicine. He will collaborate with the organization's members over three years to address urgent health challenges.
The new residency program will train 16 psychiatry residents to strengthen mental health resources in Imperial County, addressing a significant shortage of mental health professionals. The program is designed to provide high-quality behavioral health treatment, innovation, and research, with medical leadership from UC San Diego Health.
A comprehensive review reveals that early ECT sessions show substantial improvement, but subsequent sessions may lead to diminishing returns and cognitive side effects. The researchers propose a response-guided sequential treatment strategy, categorizing patients into three groups based on their response patterns.
The June issues of The American Journal of Psychiatry and Psychiatric Services feature new research on treating depression and psychosis, as well as studies exploring postpartum mental health risks. These studies highlight the importance of predicting postpartum depression and developing effective treatment models.
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Researchers at the University of Pittsburgh found that mindfulness training and non-invasive brain stimulation can significantly reduce bladder leaks and feelings of urgency evoked by specific environments or scenarios. The study, published in Continence, used transcranial direct current stimulation (tDCS) to activate the prefrontal co...
The BIAL Foundation is now accepting nominations for the 4th edition of its international award, recognizing exceptional work in biomedical research published within the last decade. Nominations are open until June 30, with a significant increase in prize amount to €350,000.
A recent epigenetic study identified RABGGTB as a promising biomarker for autism spectrum disorder, revealing extensive DNA methylation abnormalities in key brain regions. The findings suggest that studying this gene could unlock new doors to understanding ASD and lead to future diagnostic breakthroughs.
A systematic review found that positive expressive writing interventions improve psychological wellbeing, including measures of happiness and life satisfaction, but effects on physical health vary across individuals and intervention types.
UCLA Health psychiatrists and researchers will discuss Los Angeles wildfire mental health impacts, perinatal and postpartum mental health, and athlete mental health. Experts will also cover the therapeutic potential of cannabis, mind-body interventions, and quality of care for individuals with disabilities.
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GLP1-RA treatment is associated with improvements in quality of life, restrained eating, and emotional eating behavior. The treatment also provides reassurance regarding its psychiatric safety profile.
A recent study found that the average duration of ADHD medication for children and adolescents is more than three years. Long-term effects in children have not been sufficiently studied due to limited data on the safety of marketed ADHD medicines.
A new study from the University of Surrey and Université du Québec à Montréal found that controlling coaching styles disrupt athletes' physical and psychological strain. Autonomy-supportive coaches boost mental resilience, while controlling tactics lead to acute stress and burnout.
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JMIR Mental Health is seeking rigorous research on AI-powered therapy bots and virtual companions for mental health. The journal aims to explore their effectiveness, limitations, and place within broader care models.
A new UC lab-on-a-chip device developed by engineers measures the stress hormone cortisol from a patient's saliva, helping doctors diagnose depression and anxiety. The device provides objective evidence for clinicians to supplement traditional screenings, raising red flags about patients' levels of stress.
A new study found that only 39% of clinical trials report the race or ethnicity of participants involved. The research highlights the need for more comprehensive reporting and recruitment practices to ensure studies better reflect diverse populations globally. This is crucial for developing inclusive, effective, and equitable treatments.
A meta-analysis reveals significant racial and ethnic disparities in the reporting of race and ethnicity in clinical trials for pharmacotherapy of mental disorders. The study underscores the importance of equitable recruitment and reporting in clinical trials to ensure inclusive representation of diverse populations.
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Professor Carmen Sandi has made significant contributions to the understanding of stress and anxiety mechanisms in the brain. Her research focuses on the neurobiological effects of stress and anxiety, including their impact on cognition and behavior.
The Psychedelics journal has expanded its focus to include all psychoactive drugs, challenging traditional classifications and embracing a broader understanding of consciousness-altering substances. This move aims to reveal novel therapeutic applications and deepen human knowledge of the mind.
A new study at Columbia University Mailman School of Public Health found an increase in use of only psychotherapy, from 11.5% to 15.4%, and a decline in patients taking medication only, from 68% to 62%. The shift may be attributed to various factors beyond the COVID pandemic.
A study by Emory University researchers has found that spiritual health practitioners' personal experiences with psychedelics drive their careers in the emerging field of psychedelic-assisted therapy. The study introduced a novel training approach, emphasizing self-literacy and reflective learning to balance personal experience with cl...
Researchers identified risk factors for sudden unusual mental or somatic experiences, including past psychedelic use, reality distorting practices, and extensive spiritual practice. These findings can help clinicians diagnose and treat associated suffering, and inform the development of practical guidelines.
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Research found parents of children struggling with school attendance experience distress across all aspects of life, rating it as the second most threatening event. Supporting a child with school attendance difficulties imperils parental mental health and causes significant impact on daily mood and anxiety levels.
Researchers at UCLA Health are launching a clinical trial to test whether wearable nerve stimulation can ease ADHD symptoms in children with prenatal alcohol exposure. The study aims to improve focus and behavior by gently stimulating the trigeminal nerve, which is linked to attention and executive function.
A study published in Psychiatric Research and Clinical Practice found significant improvement in depressive symptoms and emotional well-being in adolescents after receiving inpatient psychiatric care. The study highlights the effectiveness of pediatric inpatient psychiatry units in improving mental health outcomes.
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A new study found that prenatal stress alters the expression of tiny RNA molecules in newborn blood, particularly in female children, affecting key enzymes in the brain's stress-regulation system. This may explain why some children are more vulnerable to developmental or psychiatric challenges.
University of California researchers developed a new drug, JRT, with reduced hallucinogenic potential compared to LSD. The compound has shown promise in treating the negative and cognitive symptoms of schizophrenia, including anhedonia and cognitive function.
Researchers found that cortisol levels were lower in survivors, while heart rate and blood pressure responses were altered. Interleukin 1B was significantly higher, suggesting potential long-term health problems despite healthy symptoms.
Researchers have found that people with cannabis use disorder have elevated dopamine levels in a brain region associated with psychosis. This could explain why frequent cannabis use increases the risk of hallucinations and delusions. The study's findings may help doctors educate patients about the potential risks of frequent cannabis u...
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Dr. Romina Mizrahi's PET-based neuroimaging sheds light on brain workings, integrating genetics, environment and imaging to understand psychiatric illness as a complex biological puzzle. She advocates for precision psychiatry paradigm with customized treatments based on molecular profiles, and calls for diversity in academic leadership.
A new study found that coordination during fear looks different in males and females, with opposite-sex pairs showing resilience under stress. Female mice were more responsive to their partners, while males tended to copy each other's actions, forming a strong social unit against stress.
A new study presented at the European Psychiatric Association Congress 2025 found that young females are more likely to experience higher social anxiety due to excessive smartphone use. The research, which involved 400 young adults, showed significant differences in mediating factors affecting problematic smartphone use between genders.
The study found significant improvements in symptoms for participants with major depressive disorder, generalized anxiety disorder, and eating disorders. Participants reported trusting and communicating with Therabot comparable to working with a therapist.
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A new digital 'translator' for brain studies enables researchers to map the brain in a standardized way, facilitating discoveries and treatments for various disorders. The open-source software allows for the comparison of brain imaging data with widely used brain atlases, promoting commonalities across findings.
A study of over 14,600 Norwegian veterans found that taking a life in combat had no subsequent impact on their mental well-being. In contrast, veterans who served in Lebanon experienced increased mental health problems and reduced quality of life after killing someone in combat.
Dr. Consuelo Walss-Bass shares her groundbreaking research on schizophrenia, emphasizing the importance of considering both genetic predisposition and environmental factors. She also discusses her work with induced pluripotent stem cells to develop personalized psychiatry and reduce stigma around mental health.
A new study suggests that nearly half of depression diagnoses could be considered treatment-resistant, with 48% of patients trying at least two antidepressants and 37% trying four or more. This highlights the need for better treatment options to support patients who don't respond to first-line medications.
A new study from the University of Turku screened school-age children for anxiety and found that a Master Your Worries programme reduced symptoms of generalised anxiety, social anxiety, and separation anxiety. The study also showed that lighter digital study materials can reduce anxiety symptoms in children.
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A study found no increased risk of suicidal events among adults taking GLP-1 receptor agonists for diabetes or obesity, but continued monitoring is warranted to identify at-risk patients. The findings ease concerns about these potential adverse effects, allowing extended use of GLP-1 RAs.
A recent study found that nearly one-tenth of US adults using prescription stimulants have a prescription stimulant use disorder. Additionally, one-fourth of users reported misuse, suggesting potential progress in addressing the mental health care gap for middle-aged women.
A study found that transgender and gender diverse individuals have lower access to appropriate mental health care and support following a psychiatric hospitalization, yet better follow-up after an emergency department visit. The study suggests that transphobia in the hospital system contributes to this disparity.
New York City residents can now access behavioral health treatment services, including cognitive therapy and medication management, at Mount Sinai's Center for Stress, Resilience and Personal Growth. The center aims to help individuals strengthen resilience, improve well-being, and navigate life challenges with confidence.
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The Mount Sinai Hospital has become the first in the US to perform a deep brain stimulation (DBS) implantation procedure as part of a clinical trial investigating its effectiveness for treatment-resistant depression. The study aims to gather evidence on the impact of DBS systems developed by healthcare company Abbott.
A new study found that sports gambling frequency is associated with the trajectory of alcohol-related problems over time. Screening and treatment interventions are recommended for this high-risk group to prevent further problems.
Dr. Nicholas Fabiano's research reveals exercise reduces suicide attempts but shows no connection to thoughts of suicide or deaths by suicide. His work proposes a paradigm shift in mental health treatment, suggesting exercise as a first-line treatment for depression.
A study published in Biological Psychiatry found that anxiety and apathy lead to different patterns in how people process uncertainty and make decisions. Participants made choices between exploring new options or sticking with familiar ones, revealing distinct computational mechanisms underlying these behaviors.
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Researchers found that brain connectivity related to cognitive control predicted substance use initiation, while cognitive control behavior did not. Stronger connectivity between the dorsal anterior cingulate cortex and dorsolateral prefrontal cortex was associated with delayed substance use onset.
The March issues of The American Journal of Psychiatry and Psychiatric Services bring together new developments in treating depression, obsessive-compulsive disorder, and schizophrenia. These journal publications highlight the latest advancements in digital mental health innovations.
Researchers found female physicians had a 53% higher suicide risk compared to females in the general population, highlighting the need for comprehensive suicide prevention strategies. The study suggests that factors such as under-recognition, inequitable pay, and work-life imbalance may contribute to this increased risk.
The University of Cincinnati is testing a collaborative care model to provide mental health resources to youth in rural communities. The program uses a tiered approach, starting with school counselors and progressing to licensed therapists and expert telehealth services, aiming to increase access and reduce barriers.
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A study published in JAMA Psychiatry reveals a significant disparity in suicide rates among US female physicians compared to non-physician females. Comprehensive suicide prevention measures are needed to address this concern and protect vulnerable individuals in the medical profession.