Articles tagged with Psychiatry
University of California researchers developed a new drug, JRT, with reduced hallucinogenic potential compared to LSD. The compound has shown promise in treating the negative and cognitive symptoms of schizophrenia, including anhedonia and cognitive function.
Researchers found that cortisol levels were lower in survivors, while heart rate and blood pressure responses were altered. Interleukin 1B was significantly higher, suggesting potential long-term health problems despite healthy symptoms.
Researchers have found that people with cannabis use disorder have elevated dopamine levels in a brain region associated with psychosis. This could explain why frequent cannabis use increases the risk of hallucinations and delusions. The study's findings may help doctors educate patients about the potential risks of frequent cannabis u...
A new study found that coordination during fear looks different in males and females, with opposite-sex pairs showing resilience under stress. Female mice were more responsive to their partners, while males tended to copy each other's actions, forming a strong social unit against stress.
Dr. Romina Mizrahi's PET-based neuroimaging sheds light on brain workings, integrating genetics, environment and imaging to understand psychiatric illness as a complex biological puzzle. She advocates for precision psychiatry paradigm with customized treatments based on molecular profiles, and calls for diversity in academic leadership.
A new study presented at the European Psychiatric Association Congress 2025 found that young females are more likely to experience higher social anxiety due to excessive smartphone use. The research, which involved 400 young adults, showed significant differences in mediating factors affecting problematic smartphone use between genders.
The study found significant improvements in symptoms for participants with major depressive disorder, generalized anxiety disorder, and eating disorders. Participants reported trusting and communicating with Therabot comparable to working with a therapist.
A new digital 'translator' for brain studies enables researchers to map the brain in a standardized way, facilitating discoveries and treatments for various disorders. The open-source software allows for the comparison of brain imaging data with widely used brain atlases, promoting commonalities across findings.
A study of over 14,600 Norwegian veterans found that taking a life in combat had no subsequent impact on their mental well-being. In contrast, veterans who served in Lebanon experienced increased mental health problems and reduced quality of life after killing someone in combat.
Dr. Consuelo Walss-Bass shares her groundbreaking research on schizophrenia, emphasizing the importance of considering both genetic predisposition and environmental factors. She also discusses her work with induced pluripotent stem cells to develop personalized psychiatry and reduce stigma around mental health.
A new study suggests that nearly half of depression diagnoses could be considered treatment-resistant, with 48% of patients trying at least two antidepressants and 37% trying four or more. This highlights the need for better treatment options to support patients who don't respond to first-line medications.
A new study from the University of Turku screened school-age children for anxiety and found that a Master Your Worries programme reduced symptoms of generalised anxiety, social anxiety, and separation anxiety. The study also showed that lighter digital study materials can reduce anxiety symptoms in children.
A recent study found that nearly one-tenth of US adults using prescription stimulants have a prescription stimulant use disorder. Additionally, one-fourth of users reported misuse, suggesting potential progress in addressing the mental health care gap for middle-aged women.
A study found no increased risk of suicidal events among adults taking GLP-1 receptor agonists for diabetes or obesity, but continued monitoring is warranted to identify at-risk patients. The findings ease concerns about these potential adverse effects, allowing extended use of GLP-1 RAs.
A study found that transgender and gender diverse individuals have lower access to appropriate mental health care and support following a psychiatric hospitalization, yet better follow-up after an emergency department visit. The study suggests that transphobia in the hospital system contributes to this disparity.
New York City residents can now access behavioral health treatment services, including cognitive therapy and medication management, at Mount Sinai's Center for Stress, Resilience and Personal Growth. The center aims to help individuals strengthen resilience, improve well-being, and navigate life challenges with confidence.
The Mount Sinai Hospital has become the first in the US to perform a deep brain stimulation (DBS) implantation procedure as part of a clinical trial investigating its effectiveness for treatment-resistant depression. The study aims to gather evidence on the impact of DBS systems developed by healthcare company Abbott.
A new study found that sports gambling frequency is associated with the trajectory of alcohol-related problems over time. Screening and treatment interventions are recommended for this high-risk group to prevent further problems.
A study published in Biological Psychiatry found that anxiety and apathy lead to different patterns in how people process uncertainty and make decisions. Participants made choices between exploring new options or sticking with familiar ones, revealing distinct computational mechanisms underlying these behaviors.
Dr. Nicholas Fabiano's research reveals exercise reduces suicide attempts but shows no connection to thoughts of suicide or deaths by suicide. His work proposes a paradigm shift in mental health treatment, suggesting exercise as a first-line treatment for depression.
Researchers found that brain connectivity related to cognitive control predicted substance use initiation, while cognitive control behavior did not. Stronger connectivity between the dorsal anterior cingulate cortex and dorsolateral prefrontal cortex was associated with delayed substance use onset.
The March issues of The American Journal of Psychiatry and Psychiatric Services bring together new developments in treating depression, obsessive-compulsive disorder, and schizophrenia. These journal publications highlight the latest advancements in digital mental health innovations.
A study published in JAMA Psychiatry reveals a significant disparity in suicide rates among US female physicians compared to non-physician females. Comprehensive suicide prevention measures are needed to address this concern and protect vulnerable individuals in the medical profession.
A recent study published in Frontiers in Psychiatry reveals a strong link between antidepressant use and weight gain, with an average 2% increase in body weight among participants. The study highlights the need to consider this association when prescribing antidepressants and monitor weight changes accordingly.
Researchers found female physicians had a 53% higher suicide risk compared to females in the general population, highlighting the need for comprehensive suicide prevention strategies. The study suggests that factors such as under-recognition, inequitable pay, and work-life imbalance may contribute to this increased risk.
The University of Cincinnati is testing a collaborative care model to provide mental health resources to youth in rural communities. The program uses a tiered approach, starting with school counselors and progressing to licensed therapists and expert telehealth services, aiming to increase access and reduce barriers.
Research from UVA Health and the Flo app finds that many women experience perimenopause symptoms as early as their 30s, including anxiety, depression, and physical problems. The study sheds light on the often-ignored transition period leading to menopause and aims to improve care and support for women approaching this stage.
Heavy screen use, particularly social media and video games, is associated with an increased risk of developing manic symptoms in U.S. preteens. The study found that prolonged screen time can lead to behaviors characteristic of bipolar-spectrum disorders, including inflated self-esteem, decreased sleep needs, and impulsivity.
Researchers used machine learning to predict diagnostic transition to schizophrenia and bipolar disorder, with schizophrenia being notably easier to forecast. By analyzing routine clinical data, the study suggests a possible approach for early intervention and personalized treatment plans.
Researchers discovered a common cognitive feedback loop used by Buddhist jhāna meditation and Christian speaking in tongues practices to achieve profound focus and joy. This 'Attention, Arousal and Release Spiral' offers insights into cultivating deep states of tranquility and bliss.
A new study from the University of Texas at Arlington found that Americans aged 65 and older who experienced parental divorce as children were more likely to suffer a stroke compared to their peers. The study analyzed data from over 13,000 older Americans and found that about 14% had experienced parental divorce during childhood.
Researchers are testing noninvasive electrical stimulation of the spinal cord to treat major depressive disorder. The trial, funded by the National Institute of Mental Health, aims to confirm whether this method reduces signaling in specific pathways related to depression.
Researchers discovered a link between neuroactive steroids in pregnant women's blood and the risk of developing postpartum depression. Measuring these molecules via a blood test could enable doctors to provide treatment sooner. The study may lead to a preventive treatment using existing prescription drugs.
Studies identified 153 cases of psychosis caused by brain lesions, which connected to a common circuit in the hippocampus. The circuit, including the rostromedial prefrontal cortex, is a promising target for transcranial magnetic stimulation therapy, potentially improving symptoms in patients with schizophrenia.
A new study published in Brain Medicine reveals that over 26.7% of schizophrenia patients experience distinct manic symptoms, which can be predicted by the severity of positive symptoms such as hallucinations and delusions.
The APA Annual Meeting will take place in Los Angeles from May 17-21, featuring over 450 educational sessions and 1,000 poster sessions on topics such as lifestyle for positive mental and physical health. Media attendees will have access to exclusive interviews with experts and embargoed research studies.
Researchers developed a biomarker test that can detect small amounts of tau protein and its misfolded forms in cerebrospinal fluid, correlating with cognitive decline severity. The test identifies early stages of tau tangle formation up to a decade before brain scans, opening doors for early-stage disease diagnosis and intervention.
A pilot study will explore whether a ketogenic diet helps stabilize mood symptoms in teens and young adults with bipolar disorder. Preliminary research suggests improvements in mood and executive function among older adults.
Researchers at UC Davis have successfully synthesized ibogaine and its related compounds using a new, efficient method. The study's findings suggest that these analogues may be useful in treating substance use disorders and other conditions, and highlight the potential for safer and more effective medicines.
The latest issues of APA journals bring together research on addictions, including substances and behaviors. The February issue of the American Journal of Psychiatry highlights research on addictions, while Psychiatric Services features articles on various mental health topics.
Research by Professor Stephen M. Stahl suggests that Jackson Pollock incorporated images into his pre-drip paintings, possibly due to spatial skills linked to bipolar disorder. The same images appear in multiple drip paintings, implying a deliberate encoding of images.
A new study found that 81% of Brazilian adolescents had experienced some form of childhood trauma by age 18, with the more types of trauma experienced increasing the risk of mental health problems. The study highlights the need for early interventions to reduce trauma exposure and mitigate its long-term consequences on mental health.
A study by ISGlobal found that exposure to cold temperatures was associated with increased internalizing problems, while heat exposure was linked to attention problems in adolescents. Psychiatric symptoms affect about one in seven adolescents worldwide, and climate change may exacerbate these conditions.
A cohort study from JAMA Network Open reveals an association between temperature exposure and increased psychiatric symptoms among adolescents in the Netherlands and Spain. The findings suggest a possible link between climate change and mental health, warranting further research across diverse climates.
A recent study published in JAMA Psychiatry found that medically recommended cannabis use is associated with a higher prevalence of cannabis use disorder and more frequent use among US adults. The study suggests that medically recommended cannabis may not be effective in reducing addiction risk compared to nonmedical use.
A study published in JAMA Pediatrics found that childhood obesity treatment can reduce the risk of serious health problems such as type 2 diabetes, hypertension, and dyslipidaemia in young adults. However, it did not have a lasting impact on depression and anxiety, which remained unchanged regardless of treatment outcomes.
Researchers found that participants who received early therapeutic interventions were significantly less likely to develop clinical depression within the first year. The interventions, which typically lasted six to twelve sessions, reduced symptoms and lowered the risk of depression by 42% in the first six months.
A new study from Vanderbilt University Medical Center shows that a clinical alerts-driven AI system can effectively prompt doctors to screen patients for suicide risk during regular clinic visits. The study found that interruptive alerts were more effective than passive alerts, leading to a 42% increase in screenings.
A new study reveals multilingualism enhances executive function skills, including focus, understanding perspectives, communication, and reduces repetitive behaviors in both autistic and non-autistic children. Parents of multilingual households report stronger overall executive function compared to mono-lingual households.
The January issue of the American Journal of Psychiatry explores the use of psychedelic medications in psychiatry, addressing basic pharmacology, clinical efficacy, and public health considerations. The series of articles aims to provide sufficient evidence for therapeutic strategies utilizing psychedelic drugs.
Emory University MD candidate Fayzan Rab's research investigates the economic and public health implications of psychedelic therapy implementation. His work emphasizes making these innovative treatments accessible to traditionally underserved communities.
A longitudinal cohort study found that state cannabis legalization is associated with increased cannabis use disorder and poisoning diagnoses. Communities with increased access to cannabis may experience increased healthcare use and costs due to these rising diagnoses.
The global prevalence of autism spectrum disorder (ASD) varies by sex and region but persists globally across all age groups. ASD is significantly higher among males, with a higher prevalence in High-Income Asia Pacific regions.
Researchers found that a blunted response to reward feedback in teens predicts the first onset of depression, but not anxiety or suicidal ideation. This study contributes to understanding neural risk factors for mental health disorders and developing new methods to assess mental health risks.
A randomized controlled trial examines the association between treatment expectancies and the relative efficacy of psilocybin versus escitalopram for major depressive disorder. The results suggest that psilocybin is more effective than escitalopram in treating depression.
A new Simon Fraser University study finds that antidepressants are associated with reduced genital sensitivity in 13% of users, compared to 1% of other psychiatric medication users. The study highlights the need for better patient education and warnings about potential side effects.
Researchers have identified structural grey matter differences in the brains of women with a history of peripartum depression compared to those without. The study found that hormone fluctuations during pregnancy and childbirth may be key to understanding this condition.
A review paper suggests that MDMA-assisted therapy can benefit military personnel with traumatic brain injuries, improving emotional and cognitive challenges. The drug may facilitate social connections, increased self-esteem, and neural plasticity, leading to improved treatment outcomes.
Researchers at UCSF found a brain signature of resilience in mice that suggests a new way to treat severe depression. Stress changes activity in the amygdala, distinguishing resilient from less resilient mice. By stimulating neurons, the team improved decision-making and reduced ruminating in less resilient mice.
Professor Lavretsky's pioneering work integrates conventional psychiatric treatments with mind-body interventions, developing novel therapeutic combinations for treatment-resistant depression and cognitive disorders. Her research has transformed approaches to mental health and aging, emphasizing whole person health and prevention.