Researchers at Virginia Tech will study the potential connection between pesticide exposure during the Persian Gulf War and an increased risk of developing Parkinson's Disease. The three-year project aims to investigate neurochemical changes in mice exposed to insecticides, which could provide insights into the disease.
Researchers found that low SES patients experience worse quality of life after treatment despite aggressive cardiac procedures. They require significant lifestyle changes, physical rehabilitation, and medication management, which can be inaccessible or misunderstood by this group.
A Georgia Tech study found that sensory neurons in animal limbs play a critical role in determining what information is received and what behaviors result. Researchers successfully transplanted female feeding claws onto males, demonstrating novel input processing by the brain.
The Pacific Northwest National Laboratory has established a new adjunct organization to coordinate nuclear nonproliferation programs, research, and policy work in the region. The center aims to promote collaboration among stakeholders for proliferation prevention and arms control policy.
Researchers at Wake Forest University Baptist Medical Center demonstrated a gene-diet interaction that affects cholesterol absorption in humans. The study found that individuals with the apo A-IV-2 gene variant absorbed less cholesterol than those without the variant, particularly on diets high in polyunsaturated fat.
A team of scientists reached a supercomputing milestone by simulating metallic magnetism at 1.002 Teraflops on a Cray T3E supercomputer. The achievement showcases the power and capabilities of parallel computers, enabling the study of larger systems and new phenomena.
The Wistar Institute has received a three-year grant to recruit and equip laboratories of new scientific investigators in regeneration, signal transduction, and brain tumor research. The institute is grateful for the support, which will help transform its programs and attract high-quality scientists.
A new surgical procedure that repairs the mitral valve may help extend and improve lives of people with severe CHF, offering an alternative to heart transplantation. The operation has shown promising results, with one-year survival rates reaching 80% and two-year survival rates at 70%.
A new study suggests that even moderate physical exertions can lead to dangerous shortages in blood supply to the heart, increasing the risk of a heart attack. The research found that routine daily activities such as driving, housework, and yard work can trigger ischemia, a condition characterized by a sudden stoppage of blood flow.
Researchers found that Ritalin reduces activation in the cerebellum and basal ganglia while increasing activation in novel areas of the brain, improving working memory in ADHD patients. This study provides new clues for developing more specific drug treatment for individuals with ADHD.
A study suggests that changes in temperature and atmospheric pressure may increase the risk of heart attack in men. Research found a significant association between extreme weather conditions and fatal and nonfatal heart attacks, particularly among those with previous heart attacks.
Researchers at Fred Hutchinson Cancer Center found that genetic techniques for matching patients with marrow donors can eliminate guesswork and improve survival rates. The study of 300 patients with chronic myeloid leukemia showed that even single mismatches in key genes don't affect long-term survival.
Marion Nestle reviews the history of olestra's approval, highlighting the FDA's decision to approve the fat substitute while requiring warning labels. She calls for changes in the regulatory system to move towards alliances with industries, increasing FDA research authority and funding.
A two-year study found that environmental stressors, such as unemployment and lack of health insurance, contribute to high blood pressure in young African-American males. An intervention team's efforts led to a 50% blood pressure control rate and a 75% decrease in emergency room visits.
The article discusses various public health issues, including tobacco control, food industry manipulation, and violence prevention. It highlights the importance of vaccination coverage estimation using parental recall, medical records, and other methods to prevent diseases such as tuberculosis.
Eleven German research centers are extending their funding by two years, totaling over DM 30 million, to develop innovative biomolecular recognition systems, biomedicine applications, and industrial solutions. This initiative supports the technology transfer from universities to regional companies.
Researchers found that combining abciximab with two low-dose boluses of reteplase provided complete blood flow to up to 35% more patients than using abciximab alone or in combination with a single dose of reteplase. This new strategy may represent an exciting new step in treating most heart attacks.
The ASU geology team is collecting and analyzing data from the Galileo spacecraft, which shows strong evidence of a liquid ocean under Europa's surface. The images transmitted by the spacecraft reveal terrain types similar to an iceberg found on Earth near Europa's surface.
Researchers found that injecting methotrexate significantly improved patient health and reduced costs for those with juvenile rheumatoid arthritis or rheumatoid arthritis. The study involved 52 patients, with 73% switching to injection treatment due to dissatisfaction with oral method side effects.
A recent study found that high levels of inflammation can impede the effectiveness of clot-busting treatment after a heart attack. Individuals with elevated C-reactive protein levels had slower responses to thrombolytic therapy, resulting in delayed revascularization and increased damage to the heart.
A University of North Carolina at Chapel Hill study suggests that consuming vitamin E and other antioxidants may help reduce the risk of knee arthritis. Middle-aged and older individuals who follow a diet rich in these compounds, such as green vegetables and tomatoes, may experience a 30% lower risk of developing osteoarthritis.
According to the study, American children now spend less than an hour per week reading and almost no time engaging in unstructured outdoor play. Meanwhile, TV viewing has become a significant part of their daily routine, with nearly a quarter of their free time spent watching television.
A 12-year study of doctors found that men who ate a diet rich in nuts had a decreased risk of dying from heart disease. In another study, people eating an oat-rich diet had lower blood pressure and reduced cholesterol levels.
The FDA analyzed 94,120 adverse event reports on silicone gel breast implants from 1984-1995. Reports increased significantly after media coverage in 1991-1992, with a shift towards more complex and varied symptom reports.
A study at Duke University Medical Center found Hispanic heart patients experienced a median delay of nine minutes from symptom onset until receiving medical therapy. Despite differences in treatment, clinical outcomes were similar between Hispanic and non-Hispanic patients.
Researchers found that liver ischemia/reperfusion injury induces a caspase-dependent apoptosis in endothelial cells. The study identified the type of affected cell and the molecular pathway responsible for the damage, opening doors to develop therapies to prevent or reduce liver preservation injury.
The REACT trial found a median delay of 2.2 hours, far lower than most U.S. studies have found, indicating an improvement in patients seeking care earlier. This decline is attributed to increased awareness and education about heart attack symptoms and the need for rapid action.
A new study by Merrill F. Elias and colleagues found that individuals with one or more risk factors for heart disease, such as diabetes, obesity, and smoking, are more likely to experience cognitive decline, including memory and learning impairments.
A recent study published in the American Heart Association meeting reveals that hypertension is a significant risk factor for heart failure among urban African Americans. The study analyzed data from cardiac catheterization patients and found a higher prevalence of heart failure among African Americans compared to Caucasians.
The tobacco control community was divided over the merits of providing legal protections to the tobacco industry, wasting time and credibility. Despite this, state and local tobacco control efforts are gaining momentum, with promise in class action litigation against tobacco manufacturers.
A study by Case Western Reserve University professor Miriam Grushka found that low doses of clonazepam can provide significant relief from burning mouth syndrome, a chronic condition affecting 1.3 million adults. The medication may prevent spontaneous firing of the cranial nerve carrying pain sensations to the brain.
A study suggests that adding 4 cents to ticket prices in professional sports venues could cover the cost of automated external defibrillators and training staff, potentially saving thousands of lives. The estimated annual attendance at major league football, basketball, baseball, and hockey games is over 120 million.
A study by Johns Hopkins Medicine found that cases of life-threatening heart muscle inflammation are declining in the US, corresponding with a decline in enteroviral infections. Since 1991, myocarditis was present in less than 5% of patients biopsied each year, correlating with reduced enterovirus cases reported by the CDC.
The US Department of Energy's Brookhaven National Laboratory is offering a new clinical trial for brain tumor patients, including those whose cancer is inoperable or has regrown. The trial aims to increase the radiation dose and expand eligibility requirements for glioblastoma multiforme patients.
A case study published in JAMA reports a patient experiencing severe withdrawal symptoms after stopping valerian supplements. The researchers emphasize the importance of asking patients about herbal product use and providing open-minded care to address potential side effects and interactions.
A new study reports a significant increase in rheumatic fever cases in the Utah area, with over two-thirds of patients showing no history of sore throat. The disease, which can lead to permanent heart valve damage, is on the rise again, sparking concerns among medical professionals.
Researchers find that a protein called Rb can keep heart cells 'dormant', preventing them from dividing and causing damage. By activating a related protein MRP1, scientists hope to induce heart cells to multiply and replace damaged ones, offering new gene therapy possibilities for treating heart disease.
A UK research team has identified vulnerable atherosclerotic plaques in human aortic tissue using near-infrared spectroscopy. The technology aims to predict which plaques are harmless and which pose a risk of rupture, enabling targeted treatment to prevent heart attacks and strokes.
Researchers at the Max Planck Institute of Metals Research have identified two temperature-dependent mechanisms controlling the brittle-to-ductile transition in materials. Dislocation mobility dominates fracture toughness above a characteristic temperature, whereas dislocation nucleation controls fracture toughness below this temperature.
A Guatemalan forest has been identified as the world's most diverse home of slime molds, with over 1,000 species collected by Ohio University researcher James Cavender. The discovery highlights the importance of these ancient organisms in maintaining soil health and fertility.
Researchers found that the thalamus, a key brain region, can remodel its connections after sensory nerves are severed, potentially leading to recovery of function after stroke or nervous system damage. The discovery sheds light on the brain's ability to reorganize and challenges scientific dogma that it is fixed after infancy.
Researchers found that the GroEL oligomeric structure is essential for biologically significant chaperonin function. The study showed that enclosure of an unfolded protein in the cage provides a mechanism to prevent protein aggregation during folding, particularly for aggregation-sensitive proteins.
Research at the University of Delaware reveals that children with Williams Syndrome may struggle to describe spatial relationships, using motion verbs less frequently and having difficulties encoding object properties and location. This cognitive deficit may be related to their impaired non-linguistic knowledge.
Scientists at University of Wisconsin-Madison successfully derive human embryonic stem cells (hES cells), which can form all cell types and tissues, holding great promise for transplantation medicine and drug discovery. The availability of hES cells opens extraordinary opportunities for tissue transplantation and cell and gene therapy ...
Researchers at Johns Hopkins Medicine successfully isolated and cultured human embryonic stem cells, a long-sought achievement. The versatile cells have the potential to rapidly study human processes and develop new therapies for various diseases, including diabetes, Parkinson's disease, and muscular dystrophies.
Scientists found that apoptosis induces the processing of EMAP II precursor protein, releasing a biologically active form that recruits macrophages. This process is crucial for tissue remodelling and coordinating cell death during embryonic development.
A new Ohio University study reveals that alligators evolved from semi-erect to sprawl postures, contrary to the conventional theory of animal posture evolution. Researchers analyzed alligator movement and found that their walking patterns are more similar to those of salamanders and lizards than previously thought.
Researchers at Johns Hopkins Medicine discovered that bearing down hard during sex can cause transient global amnesia, a temporary inability to form new memories. The study found two cases of men experiencing confusion and amnesia after sex, linked to the Valsalva maneuver and sympathetic nervous system activation.
Hydralazine improves cell health by decreasing free radicals, a chemical byproduct of normal aerobic activities. The medication has been used for decades to treat high blood pressure and appears to have a positive side effect.
Researchers at Brandeis University have pinpointed a genetic repressor that can transform diphtheria into a lethal parasite. The discovery could lead to a novel class of antibiotics that prevent bacterial virulence without inducing resistance.
University of North Carolina at Chapel Hill scientists have discovered that over-expressing a special gene in tobacco plants can manipulate the size of individual cells, resulting in smaller plant crops more resistant to dry or wet conditions. This breakthrough could lead to controlled wood cell sizes for various applications.
Researchers at UT Southwestern Medical Center have discovered how aspirin reduces inflammation by targeting a specific kinase. Aspirin inhibition prevents NF-kB activation and suppresses inflammation, making it an excellent target for developing novel anti-inflammatory agents.
Bernard Roizman's research has laid the groundwork for current efforts to develop a vaccine against HSV and gene therapies. He identified essential genes in viral replication, including a protease enzyme targeted by pharmaceutical companies.
Duke University chemists have developed novel liquid polymers that can be solidified by laser light to seal transplanted insulin-producing cells inside a selectively permeable capsule. The microcapsules reduce excessive blood sugar levels in experimental diabetic rats for up to eight days.
Researchers at UB have successfully developed perfectly aligned carbon nanotubes, bringing researchers closer to developing flat panel displays with excellent viewing angles and high resolution. The technical advances made by the team will help make flat panel displays made with carbon nanotubes affordable, using glass as a substrate.
The 'Dissertation Online' project aims to digitize theses, enabling researchers to search and access them quickly. The initiative involves adding meta-data to scientific texts, developing software tools for targeted searching, and providing guidelines for digital theses.
A recent study published in the journal Science has shed new light on the phenomenon of phantom limbs in amputees. Researchers found that the brain adapts by reorganizing nerve cells and increasing activity in pain-related areas, potentially leading to new strategies for preventing post-amputation pain and recovery of function.
Researchers at University of Wisconsin-Madison have derived and cultured human embryonic stem cells, opening doors to growing tissues from scratch. The achievement has profound implications for transplant medicine and drug discovery, offering new possibilities for treating diseases such as Parkinson's and heart disease.
A University of North Carolina at Chapel Hill study found that domestic violence preceded at least two-thirds of the cases, with black women and young women being disproportionately affected. The research also showed that alcohol regularly contributed to the deaths, and guns were involved in 54% of the homicides.
A team of researchers has determined the complete genetic sequence of Plasmodium falciparum's chromosome, identifying over 200 genes crucial for parasite functions and potential targets for new anti-malaria drugs. The findings may help develop a vaccine and improve treatment options for this deadly disease.