Researchers found that regular multi-vitamin use and long-term hormone replacement therapy can lower homocysteine levels in the blood, potentially reducing the risk of cardiovascular disease. The study tracked 353 men and women with varying levels of homocysteine, revealing significant differences in levels among participants.
Emory University researchers suggest that high estradiol levels increase MPO, which oxidizes LDL and clears it via the liver. This mechanism may explain estradiol's protective effects on cardiovascular disease.
SourceEmory University Health Sciences Center·DateNov 11, 1998
Researchers at UNC Chapel Hill have developed a novel solid-state metal sensor that can accurately measure the acidity of chemical solutions, including body fluids. The electrode may help predict cardiac muscle ischemia and offer advance warning for potential heart attacks.
SourceUniversity of North Carolina Health Care·JournalAnalytical Chemistry·DateNov 11, 1998
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Researchers propose that an inactive enzyme may contribute to memory impairment in Alzheimer's patients. A transgenic mouse study found impaired memory in animals lacking the enzyme MMP-9, supporting the idea that its inactivity plays a role in the disease.
A study of 22,454 patients found that most deaths occurred in the first two hospital days, suggesting that extended stays may not provide additional benefits. Hospitals could optimize patient care by providing necessary procedures within three days without compromising quality.
Researchers found genes encoding for glutamate receptors in plants, indicating a common cell-to-cell communication system between plants and animals. This discovery may explain why certain plants produce neuroactive compounds that activate human brain receptors.
A recent study by the American Heart Association found that women with heart disease are more likely to experience chest pain during mental stress. The study tested the effects of psychological stress on ischemic heart disease and found that heart rates increased twice as much among participants who reported chest pain.
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BioStratum's gene-attenuated virus vaccines protect macaque monkeys against HIV-1-based viruses. The study demonstrates the efficacy of two vaccines in preventing AIDS development in 11 out of 12 monkeys.
SourceNoonan/Russo Communications·JournalJournal of Virology·DateNov 11, 1998
Researchers found that dissolved humic material can bind radionuclides, speeding contaminant migration. This process has significant implications for existing and future waste facilities, as low levels of humics in groundwater can facilitate transport.
SourceAmerican Chemical Society·JournalEnvironmental Science & Technology·DateNov 11, 1998
Researchers found a strong association between leg length discrepancies of two centimeters or more and an increased risk of knee arthritis by up to 70 percent. Simple adjustments, such as special shoes or exercises, could help prevent or slow progression of osteoarthritis in millions of people.
SourceUniversity of North Carolina at Chapel Hill·DateNov 11, 1998
The new guidelines provide recommendations for diagnosing and treating heart valve disease, covering common disorders such as mitral valve prolapse and aortic stenosis. It also addresses rare ailments, provides advice on evaluating and treating adults, teens, and pregnant women with defective valves.
A large clinical trial found that amlodipine, a calcium channel blocker, did not prevent the progression of coronary artery atherosclerosis but slowed it in the carotid arteries. Amlodipine significantly reduced angina pectoris and related procedures like bypass surgery.
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Penn physicians developed clinical guidelines for herbal therapies, emphasizing the importance of understanding herbal agents' properties and potential risks. The guidelines caution against using certain herbal products, especially those with toxic effects, and recommend discussing risks and benefits with patients.
SourceUniversity of Pennsylvania School of Medicine·JournalJAMA·DateNov 11, 1998
A recent study found that almost three in five smokers who undergo heart surgery continue to smoke after their procedure. Researchers examined 1,829 individuals who had bypass surgery or angioplasty and found that younger patients, African Americans, and those with a prior history of heart attack were more likely to be 'die-hard' smokers.
Researchers at Virginia Tech successfully cultivated pharmaceutical-producing tobacco, with the goal of producing human proteins for use in pharmaceuticals. The high-density plant cultivation method produced encouraging data and demonstrated flexibility in tobacco varieties.
Researchers at Emory University found that vitamin E supplementation decreased autoantibodies associated with oxidation of lipoproteins in healthy women. The study suggests that antioxidants like vitamin E may help attenuate oxidation and reduce the risk of atherosclerosis.
SourceEmory University Health Sciences Center·DateNov 11, 1998
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