An Australian-led team has captured the first picture of the sky in which the Milky Way no longer blocks our view of the Universe beyond. The new survey, HIPASS, used CSIRO's Parkes radio telescope to detect large numbers of small and faint galaxies, as well as giant clouds of gas that give off no light.
Familial adenomatous polyposis (FAP) patients treated with Aptosyn experienced a clinically significant reduction in precancerous colon polyp formation after six months of therapy. Over 18 months, patients showed an overall 75% reduction in polyps, highlighting the compound's potential as a treatment for FAP.
Researchers at CWRU's Frances Payne Bolton School of Nursing are studying the effects of a new intervention program on cardiac patients' exercise habits. The CHANGE program uses small-group counseling and behavior modification techniques to help patients maintain long-term, positive exercise habits.
Researchers from the University of Florida College of Medicine have developed a new therapy using bacteriophages to treat Vibrio vulnificus infections. Most mice injected with both the bacterium and a deadly bacteriophage survived what would normally be a fatal infection, demonstrating the effectiveness of this approach.
A study found that 40% of cancer patients use unconventional medical therapies and do not report this information unless specifically asked by their physicians. These therapies, such as mega-doses of vitamins and herbal supplements, can potentially interfere with radiation treatment.
Introgen presents Phase I trial results on RPR/INGN 201, showing safety and expression in ovarian cancer, lung carcinoma, and glioblastoma patients. The therapy has demonstrated significant potential in treating these life-threatening conditions.
Researchers train embryonic stem cells into oligodendrocytes, which can rewrap nerve axons and remyelinate damaged spinal cords. The study demonstrates a potential approach to restoring neurological function in patients with conditions such as multiple sclerosis and spinal cord injury.
Researchers found that estrogen use reduced cognitive decline in women with e2 and e3 ApoE alleles, but not in those with e4 variants. Estrogen also showed protective effects on carotid wall thickening and atherosclerosis.
Dr. Achilles A. Demetriou will present information on the bioartificial liver (BAL), an external device that cleanses blood plasma through synthetic and biologic materials, during Digestive Disease Week. The BAL has completed a Phase I clinical trial at Cedars-Sinai and is now in a large multi-center study.
A new minimally invasive radio-guided parathyroidectomy (MIRP) technique allows surgeons to remove parathyroid glands with fewer complications, reducing surgery time from several hours to just 30 minutes. This outpatient procedure also enables patients to go home within a few hours, compared to days of hospitalization.
Abarelix depot-M successfully suppresses testosterone levels, achieving suppression by day 8 and maintaining it from day 29 through day 85. The studies validated PRAECIS' core technology and demonstrate a potentially new treatment option for prostate cancer.
A study by Johns Hopkins Medicine found that 31% of recent popular press articles on epilepsy contained gross mistakes, including inaccurate science and exaggerated treatment claims. The print media often reflect and shape views about epilepsy, but also perpetuate misconceptions that can shame patients.
The study confirms that M-Vax increases the survival rate of patients with advanced Stage III melanoma, even after disease recurrence. Patients who developed an immune response against their melanoma had a far better outcome, with a five-year survival rate of 65%.
Matthew Warman, an assistant professor of genetics and pediatrics at CWRU, has been selected as a Hughes assistant investigator by the Howard Hughes Medical Institute. He will receive funding for his research on rare and common human genetic diseases, aiming to improve human health.
Researchers studied rhesus macaques from birth to young adulthood, finding that those with high cortisol levels responded more strongly to stress and drank more alcohol as adults. The study's findings suggest early life stress can influence later alcohol consumption and offer a promising biological marker of risk.
A new Ohio University study found that weight training does not increase cholesterol levels in healthy young men and women, but reduces body fat and increases muscle strength. The research counters previous studies and news reports giving weight lifting a bad name.
A study found that faucet handles and phone receivers are high-risk areas for transferring bacteria and viruses to hands and faces. This could lead to diseases like diarrhea and infection if proper hygiene is not practiced. The researchers also highlighted the potential for household items like sponges and telephones to spread infections.
A Phase III trial shows long-term hormone suppression can control recurrence and improve survival in prostate cancer patients. The treatment significantly reduces disease-free survival, local progression, and freedom from distant metastasis.
A new study found that elderly men who rate their health as poor are more likely to die than women with similar ratings. Men's perceptions of their health are a better predictor of death risk, while women consider emotional distress from various factors, reducing accuracy in predicting mortality.
Researchers used a mouse model to identify changes occurring in nerve cells before the onset of Huntington's disease. They identified several signaling molecules that could be targeted for future therapies.
Researchers discovered a sub-group of alcoholics who self-medicate low serotonin levels with carbohydrates when not drinking. Carbohydrates increase serotonin levels, similar to alcohol, and this study provides insight into treating alcoholics with disturbed serotonergic function.
The company presented Phase II data of tgDCC-E1A, a lead cancer therapy, which showed a 45% objective response rate in patients with recurrent head and neck squamous cell carcinoma. Preclinical studies also demonstrated the ability of E1A to sensitize tumors to radiation and chemotherapy.
A study found that infant monkeys raised without adult supervision experienced higher cortisol levels, indicating increased stress, which later led to heavy drinking as adults. This suggests a link between early life experiences, sensitivity to stress, and subsequent alcohol consumption.
A Yale study found that older persons with acute illnesses prefer hospital care over home care, even if the outcomes are equally good. Home care is a viable option only if it provides the same level of care as the hospital.
Chronic alcohol consumption combined with thiamine deficiency may have a synergistic effect on the brain, causing impaired learning, reference memory, and cognitive functions. Thiamine supplementation can exacerbate this effect, and some experts suggest that food supplementation or beer enrichment may be more beneficial.
The X-40A test vehicle, built by Boeing, is being shipped to NASA's Dryden Flight Research Center at Edwards, Calif., for a series of ground and air tests. The X-37 project aims to demonstrate technologies in the orbital and reentry environments for next-generation reusable launch vehicles.
Scientists at Northwestern University discovered that polyglutamine aggregates are toxic and can bring healthy proteins to aggregate with them. The growth of these aggregates can be suppressed by molecular chaperones called heat shock proteins. This finding provides a new model for understanding the common pathology of neurodegenerativ...
Researchers will grow functional human heart tissue, aiming for a fully functional heart in 10 years. They'll use scaffolding, stem cells, and patented technology to engineer cardiac muscle and valves.
Researchers found that watching the video reduced anxiety and stress in patients before surgery, while also decreasing cortisol levels and pain medication needs. The study suggests that preparing for an operation by watching a videotape may improve coping abilities.
A new study shows Bexxar produced tumor shrinkage in 97% of patients with advanced-stage, low-grade non-Hodgkins lymphoma. Most patients achieved complete remission, with no sign of cancer, and molecular remissions lasting up to three years.
The data from an ongoing Phase 1/2 trial of O-Vax in patients with advanced ovarian cancer indicates that the vaccine induces a positive immunological response, as measured by a delayed type hypersensitivity test. Favorable clinical responses were also observed, including complete regression of tumors and normalization of CA-125 levels.
A study found that recently detoxified male alcoholics experience significant cognitive and motor deficits, particularly in gait and balance. These impairments can lead to an increased risk of falls and may be linked to the 'premature aging hypothesis,' where the brains of older alcoholics resemble those of non-drinkers.
A new University of Florida study reveals that consuming folate-rich foods daily can significantly reduce homocysteine levels, a risk factor for heart disease, in postmenopausal women. The research suggests that improving folate intake is crucial for older women's health.
Scientists at Max Planck Institute discover novel potassium current activated by calcium, shaping neural signal frequency. SK channels play a crucial role in neuronal adaptation, influencing brain function and learning. The study resolves a long-standing controversy between electrophysiology and apamin-binding studies.
The Pew Fellows Program in Marine Conservation awards $150,000 to ten ocean ambassadors from five continents tackling pressing issues like marine pollution and coastal conservation. The 2000 recipients will conduct interdisciplinary projects applying sound science to urgent challenges.
A recent study of female participants with functional gastrointestinal disorders found that catastrophizing and low perception of power over symptoms worsened health outcomes. The researchers suggest that cognitive behavioral therapy may help alleviate these negative coping strategies and improve gastrointestinal symptoms.
Researchers have identified a water extract from potatoes that inhibits the attachment of certain bacteria, such as oral streptococcus and E. coli, to their target tissue. This finding could provide a new direction for antibiotic research and potentially help solve the growing problem of antibiotic resistance.
A new study published in Developmental Psychology found that older preteen children (6th grade) are at risk of chronic partial sleep deprivation, leading to increased daytime sleepiness. Family stress, parental education, and age may contribute to this issue, highlighting the need for better sleep habits and support.
Researchers conducted a Phase II trial of adenoviral p53 gene transfer with radiation therapy, showing 29% of patients achieved local tumor control and 12 of 15 had no active cancer. The study demonstrated considerable promise for combined treatments, comparing favorably to a control rate of less than 20% in patients treated with radia...
A study published at ASCO suggests that treating cancer patients on clinical trials is not more expensive than standard treatment. The research found average charges of $57,542 for trial patients and $63,721 for control patients, highlighting the potential for increased access to high-quality care.
A Phase II trial found a 40% response rate with low-dose anti-VEGF combination therapy, compared to 24% for high-dose and 17% for chemotherapy alone. Median survival increased by 2 months with the low-dose treatment.
Researchers at Johns Hopkins presented Phase I study results for Taxoprexin DHA-paclitaxel, a novel taxane that tolerates high doses with minimal side effects. The drug delivers more therapeutic agent to tumor cells and less to healthy tissues, improving safety and effectiveness.
Researchers have discovered a metal wire with 'memory' that can help compress broken bones, leading to quicker healing times and better fusion of the bone. The alloy, Nitinol, resists loosening even after being absorbed by the bone, applying consistent pressure to promote proper healing.
Scientists at the University of Michigan School of Dentistry have developed a method to create bones from skin and gum tissue cells, which can be used to replace missing bone in living rats. The engineered cells not only deliver bone-forming proteins but also participate directly in bone formation.
Scientists report evidence that high-temperature superconductivity in copper oxides is linked to two-dimensional spin excitations, contradicting the long-held idea that stripes are responsible. This finding sheds new light on the mechanism behind this phenomenon.
The Deutsche Forschungsgemeinschaft conference highlighted the need for research into adiposity, which causes physical disorders and increases the risk of contracting illnesses such as diabetes and cardiovascular disorders. Scientists called for guidelines to support doctors and patients in their struggle against obesity.
Researchers from various fields will discuss normal development and understanding of the visual world, as well as brain failures to recognize objects. The symposium aims to bring together converging perspectives on how our brains organize and interpret visual information.
A team of researchers at Sandia National Laboratories has developed an intelligent software agent that can defend itself and other computers against cyber attacks. The agent uses a multi-agent collective approach to detect and respond to unusual requests or commands, providing real-time protection against various types of threats.
Researchers have identified a compound in tobacco that inhibits an enzyme that breaks down key brain chemicals, potentially offering protection against Parkinson's disease. The discovery opens up new avenues of research and may lead to the development of neuroprotective compounds.
Researchers have identified a new protein synthesis mechanism at synapses that regulates synaptic strength, leading to long-term memory storage. The study reveals that experience or activity in the mammalian brain can modify individual synapses on an individual basis.
A team of scientists led by Li-Huei Tsai found that the enzyme calpain triggers neurodegeneration in brain cells, similar to Alzheimer's disease. The discovery proposes a common mechanistic link between toxic insults and brain cell injury, offering potential targets for drugs to slow or stop progression.
The Marshall Center's Fastrac engine team has developed a 60,000-pound-thrust engine with reduced costs through innovative design and commercial off-the-shelf parts. The team achieved this feat in under three years, significantly faster than usual for rocket engines.
Researchers found that brief daily awakenings reduce ventilation duration, cut ICU stays by one-third, and lower healthcare costs. Patients who had daily sedative breaks recovered much more quickly, with reduced need for diagnostic tests related to mental status.
A custom-made vaccine created from a patient's own cancer tumor cells has proven effective in prolonging the survival of patients with malignant melanoma. The vaccine resulted in a 47% five-year survival rate among 214 patients with disease spread, outperforming standard treatment.
ReQuip significantly reduces the risk of levodopa-induced dyskinesia in Parkinson's disease patients. The five-year study shows that ReQuip monotherapy can reduce dyskinesia incidence by seven times and effectively control early PD symptoms.
A new study found a combination therapy of Serzone and psychotherapy to be highly effective in treating chronic forms of major depression, with an 85-percent response rate. The treatment approach produced significant improvement in patients sooner than psychotherapy alone, and with fewer side effects.
Researchers found two protein biomarkers, cIAP-1 and XIAP, that correlate with distant metastasis-free survival in prostate cancer patients. Elevated levels of these proteins were associated with a higher risk of relapse after radiation therapy.
Researchers have reported promising results from a Phase I-II trial of an ovarian cancer vaccine made from patient's own cancer cells. Eight of 10 patients showed immunological response, with one experiencing complete tumor disappearance and CA125 levels normalization.
Researchers found that concurrent chemotherapy and daily chest radiation can help lung cancer patients live longer, with an average survival of 17 months. In contrast, sequential treatment resulted in an average survival of 14.6 months.
A study of rural teenagers found lower asthma rates among farm-raised teens, while respiratory syncytial virus (RSV) bronchiolitis in infancy strongly correlates with later development of asthma and other breathing issues. Asthma experts emphasize the need for tailored management strategies addressing different stages of the disease.