A national study found that 85% of chronically depressed patients improved after three months of treatment combining antidepressant Serzone with Cognitive Behavioral Analysis System of Psychotherapy (CBASP). The combination therapy was more effective than either medication or psychotherapy alone for treating chronic depression.
Researchers found that over 12% of a sample must be covered in soot for people to accurately detect the difference between clean and dirty sheets. The study provides guidelines for determining when to clean and protect fine art from soot damage, helping museum designers preserve valuable collections.
According to the report, Indiana's forests have expanded significantly since the 1960s, with 85% of timberlands in private ownership. The number of trees has increased to 2 billion, providing habitat and food for wildlife.
Susan Okie, a medical reporter at The Washington Post, has won the 2000 American Society for Microbiology (ASM) Public Communications Award. Her two-part series on tuberculosis highlights the challenges of controlling this deadly disease and emphasizes the need for new medicines and vaccines to eradicate it.
Astronomers used Chandra to survey the Hubble Deep Field North, detecting six galaxies that defy expectations with their high rate of star formation and giant black holes. The discovery indicates that only 15% of submillimeter sources can be luminous X-ray sources.
Maternal mortality remains a global health problem, despite significant international efforts. A new $4.95 million grant will aid in developing tools to diagnose and treat ectopic pregnancy, prevent preeclampsia, and identify women at risk of life-threatening infections.
A study published in The New England Journal of Medicine confirms Requip's efficacy in managing early Parkinson's disease symptoms with a low risk of developing dyskinesias. Patients taking Requip alone were seven times more likely to remain dyskinesia-free than those on levodopa alone.
Researchers discovered a new enzyme that moves along DNA, separating its sides, and has a unique gait dubbed the 'quantum inchworm'. This finding may aid in building nanomachines for gene delivery and cancer treatment.
A recent study by the NHLBI found that reducing dietary sodium can significantly lower blood pressure in people with and without hypertension. The study, which involved 412 participants, showed that the lowest sodium intake produced the greatest blood pressure reduction, regardless of diet type.
Researchers found that blocking the interaction between two naturally occurring molecules restricts tumor growth and spread in mice. Inhibition of RAGE-amphoterin interaction decreased tumor cell growth, migration, and invasion without affecting angiogenesis.
Researchers are conducting a nationwide study to identify genes that predispose individuals to major mental illnesses such as depression, bipolar disorder and schizophrenia. The study aims to develop better treatments and tailored medications for these disorders, which often run in families.
Researchers link HIV-protease inhibitors to increased diabetes risk due to impaired glucose storage, prompting reevaluation of screening methods and development of new treatments. Up to 83% of patients on the drugs develop excess belly fat and type 2 diabetes.
The Project Link program combines innovative treatments with a culturally diverse staff and close cooperation with the criminal justice system to improve patients' lives. Participants spent an average of 45 days in jail and 8 days in the hospital, compared to 104 and 114 days respectively before entering the program.
The National Toxicology Program (NTP) will review testing recommendations for future studies on DNA-based therapies, dietary supplements, and occupational chemicals. The agenda includes discussion of DNA-derived vaccines, gene therapies, and radio frequency radiation emissions from cellular phones.
Researchers identify a component of Chilean tarantula venom that specifically blocks stretch-activated channels, implicated in various physiological processes. This peptide toxin shows promise in treating conditions such as congestive heart failure, heart attacks, and brain tumors.
A University of North Carolina at Chapel Hill study found that shorter hospital stays may actually increase the likelihood of breastfeeding. The research suggests that giving clinicians and mothers more decision-making power over discharge timing can support breastfeeding, even in cases where risk factors suggest otherwise.
Research suggests that rising CO2 levels may cause a 40% reduction in coral reef growth over the next 65 years. The team found no evidence of acclimation to reduced carbonate levels, highlighting the negative impact on coral reefs. This finding has significant implications for the increasing vulnerability of many reefs to other stressors.
The symposium aims to strengthen research relationships between university scientists and industry experts in the rapidly growing field of polymers. Robert Waymouth will deliver three lectures on polyolefin catalysis and its applications.
A new study links high hostility levels to an increased risk of coronary artery calcification and heart disease in young adults. The researchers found that those with higher hostility scores were nearly 3 times more likely to develop coronary artery calcification than those with lower scores.
Recent safety studies by the National Toxicology Program will be reviewed by a public meeting on May 18. The studies include chloral hydrate, napthalene, and indium phosphide.
A new study by Northwestern University Medical School researchers found that high blood sugar levels are associated with an increased risk of pancreatic cancer death. The study analyzed data from nearly 40,000 men and women who were screened for cardiovascular disease risk and followed up for an average of 25 years.
Patients with generalized social phobia can benefit from long-term sertraline HCl treatment to prevent relapse and reduce symptoms. The study found that continued use of sertraline significantly reduced the risk of relapse compared to placebo, while also improving quality of life.
A new UF study contradicts dire predictions that prenatal cocaine exposure leads to misbehavior in toddlers. Researchers found no significant behavioral problems in cocaine-exposed children, suggesting poverty and environment may be the cause.
The conference brings together theoreticians and practitioners to discuss the application of algorithms in industry. Experts share their experiences and knowledge on topics such as enabling algorithm use, repository development, and meeting specific client needs.
The AAPS Workshop on Analytical Methods Post Approval Changes and Packaging Post Approval Changes brings together experts to discuss scientific issues related to post-approval changes. Speakers will explore viable approaches to predict the impact of these changes on drug quality.
Two studies in Annals of Internal Medicine explore cost-effectiveness of statins on specific populations. Statin therapy was found to be reasonably cost-effective for patients aged 75-84 years old with a history of heart attack, increasing life expectancy by four months while costing $18,800 per quality-adjusted life year. Cost-effecti...
Dr. Kisilevsky and his team aim to develop agents that prevent protein-carbohydrate binding, effectively inhibiting malaria parasite infection. The project builds on expertise gained in amyloid and Alzheimer's research, exploring novel ideas at a molecular level.
A large clinical trial is underway at UCSF to study a combination drug therapy for osteoporosis, using recombinant human parathyroid hormone (1-84) and alendronate. The trial aims to combine agents that speed up bone formation and resorption with those that slow down resorption, resulting in a net gain of bone strength.
Researchers have successfully created genetically engineered mice that cannot produce their own vitamin C, a nutrient essential for growth and healthy tissues. These 'humanized' mice will aid in understanding vitamin C's role in diseases such as heart disease and cancer.
Barbara Fredrickson's broaden-and-build model asserts that positive emotions broaden thinking and action, creating an upward spiral that builds strength, character, and health. Her research shows positive emotions reduce cardiovascular activity and increase psychological resilience.
The Virginia Heritage Project will create an integrated database of thousands of tagged finding aids describing the history and culture of African-Americans in Virginia. Researchers can access primary sources online, saving time and money.
A study by Princeton researchers estimates that 8-18 million Americans may identify with more than one race in the 2000 census, several times greater than previous estimates. The vast majority of likely multiple race respondents chose 'White' when faced with the traditional single-response race question.
The two-part documentary series explores how West Virginia became a separate state, with equal support for northern and southern causes. The series highlights the military actions and events that led to West Virginia's secession from Virginia and its subsequent development as a distinct state.
A new study reveals that older Latina women are at a higher risk of having low birth weight infants, contradicting previous assumptions. The research, which analyzed data from over 220,000 Mexican-origin Latina women, found that maternal age was a significant factor in determining infant birth weights.
Researchers sequenced a region of the house finch genome, showing similarities to mammalian genomes in structure. The study found that birds' compact genomes favor metabolic demands related to flight, supporting shared basic genome structure with mammals.
A new study suggests that most gamma radiation reaching Earth is leftover energy from massive shock waves caused by gravitational forces. The collision of electrons with low-energy photons could be a sign of ordinary matter captured within intergalactic clouds, shedding light on the 'missing matter' puzzle.
A four-month study of over 200 ambulance arrivals found potential for injury to children and other occupants in urban medical centers. Researchers identified opportunities for prevention, including securing EMS equipment and ensuring proper restraint.
Researchers are developing cost-effective methods to capture and store carbon dioxide, with potential to reduce global warming impact. The DOE-funded projects include membrane development, vortex tube separation, and algae-based carbon sequestration.
Researchers create molecular footprints of information to encode diverse data, including music, on a single silicon surface. The novel approach enables precise control over structure and chemical composition of nano-devices, potentially leading to breakthrough electronic tools.
Researchers found that higher doses of electroconvulsive therapy (ECT) were more effective in relieving depression, with 66.7% of patients experiencing relief compared to 38.9% on lower doses. However, the high-dose group also experienced temporary memory disturbances and longer recovery times.
A door-to-door campaign in Auckland, New Zealand raised awareness of meningococcal disease among at-risk populations. The campaign, initiated in 1998, used lay educators to visit over 11,000 homes and deliver key messages about the disease.
Researchers at OHSU have discovered new synapses between nerve cells and oligodendrocytes, suggesting a key role in myelin formation. These connections may help answer questions about how nerve cells regulate myelin production, potentially leading to treatments for multiple sclerosis.
Researchers at the University of Southern California have discovered a unique nuclear DNA structure that helps elucidate the process of immunoglobulin class switching. This finding may provide insights into B cell cancer, such as Burkitt's lymphoma.
A recent study published in Heart journal has found that recreational cocaine use promotes the formation of blood clots, leading to an increased risk of heart attacks. The research, which monitored 14 young adults after they received a dose of cocaine, showed that even occasional use can have significant effects on cardiovascular health.
Biologists at UCSD discovered that the Argentine ant's ability to thrive in California is due to its low genetic diversity, which allows it to recognize and accept individuals from the same colony. This has led to the formation of a single, large 'supercolony' that dominates native species.
A new Ohio University study reveals that e-commerce has increased the value of used and rare books, with online sales accounting for a 12.5% increase in book sales. The study also found that prices for rare books have climbed, while common titles have seen stabilization or decrease in price.
Astronomers have found evidence of a supermassive black hole similar to the one in our Milky Way in a nearby galaxy. The discovery was made using spectra from the Hubble Space Telescope and reveals details about the object's mass that could help scientists understand how these celestial phenomena are formed.
A new study found that two to three drinks significantly affect mariners' performance, making it twice as long to correct system failures after consuming alcohol. The researchers recommend lowering the current blood alcohol concentration limit for commercial ship personnel to mitigate this risk.
A University of Pittsburgh researcher found that children exposed to lead have a significantly greater odds of developing delinquent behavior. The study showed that delinquent youths had significantly higher mean concentrations of lead in their bones compared to non-delinquent controls, with results true for both whites and African Ame...
A large UM study found that mycophenolate mofetil (MMF) reduces the risk of losing a transplanted kidney due to chronic failure better than azathioprine (AZA). MMF protects against kidney loss even when acute rejection prevention effects are eliminated, with nearly 86% of MMF-treated kidneys surviving four years.
Molecular geneticists have characterized gene mutations in families with pseudoxanthoma elasticum (PXE), a rare inherited disorder that can lead to blindness, early heart attacks, and cardiovascular disease. The study provides the basis for DNA-based carrier detection, prenatal testing, and improved diagnosis of the condition.
Researchers at Oregon State University have discovered a new class of chemicals called 'bruchins' that signal a plant to form a benign tumor, helping prevent insect infestation. The unusual chemical can induce tumor formation even at low levels, with precise effects on the plant.
A recent study found that a half-day safety program for kindergarten students showed minimal improvement in basic safety skills. The research compared two groups of children, one that participated in the program and another that did not, but found no significant difference in their scores. This suggests that many safety programs, like ...
Researchers have used new methods to track the evolution of human chromosomes over a 130 million-year period, finding that one chromosome is shared only with chimpanzees. By examining analogous chromosomes in other mammals, scientists can reconstruct how human chromosomes evolved from ancient origins.
Researchers have developed a model called Reconstruction After Feedback with Take the Best (RAFT) that explains how hindsight bias occurs. Consistent with the model, experiments found that knowledge of nutrition values was updated with feedback, reducing hindsight bias.
Pediatric heart transplant patients with a specific cytokine gene profile may be identified as 'rejecters', indicating a higher risk of rejection. Researchers plan to evaluate the screening's value in tailoring immunosuppression to prevent serious episodes and graft loss.
A study by Thomas Jefferson University found that Pennsylvania's Early Discharge legislation resulted in longer hospital stays for new mothers and babies, increasing maternal and infant healthcare costs. The average maternity stay rose from 34 to 48 hours, with estimated annual costs of $20-25 million.
Researchers found that mice with a missing gene for Protein Kinase A drank twice as much alcohol and recovered in about 65 minutes from intoxication. The study suggests PKA may play a role in regulating voluntary consumption of alcohol and sensitivity to its effects.
A new international study found that parents of premature infants expressed strong interest in being involved in treatment and resuscitation decision-making. The majority felt that discussion on therapy was adequate, but suggested improvements could be made through better communication and simpler terminology.
Researchers found that PKA signaling regulates both alcohol-seeking behavior and sensitivity to alcohol intoxication in mice. Mice with a mutation in the RIIb subunit of PKA drank nearly twice as much 20-percent alcohol solution, while recovering faster from sedative effects.