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Science News for August 28, 2000


Early results show irradiating donor organ reduces rejection in intestine transplants, say researchers at international meeting

A new strategy involving radiation and bone marrow infusion appears to effectively reduce immune system attack in intestinal transplant recipients. Five patients who received irradiated intestines experienced no episodes of rejection for up to four months, while two control patients experienced typical rejection within weeks.

SourceUniversity of Pittsburgh Medical Center·JournalTransplantation Proceedings·DateAug 28, 2000

Scientists pinpoint possible cause for debilitating sleep disorder narcolepsy

Researchers found a dramatic reduction in hypocretin neurons in people with narcolepsy, suggesting a potential link to neurodegenerative processes or autoimmune responses. The study suggests that replacing missing hypocretin cells may reverse symptoms of the disorder, paving the way for new treatment options.

SourceNIH/National Institute of Neurological Disorders and Stroke·JournalAnnals of Internal Medicine·DateAug 28, 2000