OHSU researchers successfully delivered chemotherapy across the blood-brain barrier for patients with primary central nervous system lymphomas. The study showed that 93% of treated patients achieved a complete response and participating centers outperformed OHSU in blood-brain barrier disruptions.
John P. Holdren receives Tyler Prize for his leadership in research and policy on global energy and environmental issues. His work has shaped new understanding and policies on sustainable development, climate change, and nuclear nonproliferation.
A qualitative study of gay and lesbian physicians in training found that those coping with first awareness of themselves were especially vulnerable to negative reactions. Proactive training programs acknowledging diversity and using professional role models can improve the situation.
The nasal spray flu vaccine protected young children against the A/Sydney flu strain with an 86% efficacy rate, reducing disease severity and middle-ear infections. The two-year study showed overall protection of 92% and significant cross-protection against other strains.
A University of Florida researcher has developed a genetically altered bacteria strain, called an effector strain, that can permanently prevent tooth decay. The new strain, constructed from the naturally occurring bacterium Streptococcus mutans, breaks down food sugars and thrives on high-sugar diets.
A recent study found that communication drives the use of the Internet at home, with individuals using e-mail in more sessions and consistently than they use the World Wide Web. The study, which tracked 229 people's behavior over a year, shows that social uses of the Internet are strongly favored by novice users.
The NEAR spacecraft is set to embark on a historic asteroid rendezvous with Eros, the largest near-Earth asteroid discovered so far. Using its instruments, scientists will study the asteroid's chemical and physical features, evolutionary history, and magnetic field to gain insights into asteroids' origins.
A new treatment combination of paclitaxel and carboplatin has shown encouraging results in a clinical trial, achieving a 62% response rate and a projected 72% one-year survival rate. The treatment, which is compatible with prior anthracycline therapy, offers additional benefits for women with metastatic breast cancer.
The composite liquid oxygen tank is the largest ever made and will be the first to fly on a launch vehicle, aiming to reduce launch costs from $10,000 per pound to $1,000. The X-34 flying laboratory is being developed to demonstrate technologies for safer and more efficient reusable launch vehicles.
The article highlights the need for synergy between the Internet and evidence-based decision-making in healthcare, citing examples like the Cochrane Collaboration. The authors argue that technological advancements will enable multisensory modes of communication and ubiquitous computing, revolutionizing health initiatives.
Researchers have developed a new technique called Doubly Vibrationally Enhanced (DOVE) Four Wave Mixing, which uses two infrared lasers to study molecular connections and vibrations. This method allows chemists to gain insights into complex scientific problems, such as bacterial resistance to antibiotics and soil weathering.
A study of 9-month-old Cree infants found that one-third were anemic, with breast-fed babies facing higher risk. The authors recommend supplementing breast milk with iron after 6 months to prevent severe neurologic and developmental effects.
Researchers at Johns Hopkins and CIBA Vision Corp. have identified a natural chemical substance responsible for blinding blood vessel growth in patients with diabetic retinopathy. The study found that blocking this substance can completely stop abnormal vessel growth, offering new potential treatments for the condition.
Researchers found that people living near industrial hog farms in North Carolina reported more frequent symptoms such as headaches, runny noses, and eye irritation. The study also showed that the quality of life for these residents was significantly reduced compared to those living near cattle farms or without livestock operations.
A Penn State study found that serving larger portions to 5-year-olds but not 3-year-olds leads to increased food intake and calorie consumption. This early learning period marks a significant milestone in children's eating habits, highlighting the importance of portion control for healthy development.
A two-year study of 741 elderly patients found that those receiving general anesthesia had improved mobility and daily functioning compared to those with spinal anesthesia. The researchers are unclear about the underlying reason for this difference, but suggest potential nerve damage may be involved.