Researchers at UNC Lineberger Comprehensive Cancer Center are conducting a clinical trial using a genetically engineered protein fragment to stimulate the immune system to recognize and kill breast cancer cells. The goal is to treat advanced breast cancer, where the disease has spread beyond the breast.
Scientists have developed a fruit fly model to study malaria parasite development, which may lead to the creation of mosquitoes resistant to malaria. The research could also pave the way for better anti-malarial drugs and transmission-blocking vaccines.
Scientists at Max-Planck Institute report strong violations of classical constraints on electron mean free path in metallic fullerenes, challenging the semi-classical approach. The study suggests that metallic behavior can occur with a mean free path less than atomic distance, indicating a breakdown of the semi-classical picture.
Researchers found that trans-Resveratrol modulates NF-kappa B activity, turning off a natural protective mechanism that prevents cancer cells from being killed. The study suggests that consuming more grapes and grape products may help prevent or treat certain cancers.
A 10-year study of 4,162 elderly adults found that whites are nearly three times more likely to be prescribed antidepressant medications than African Americans. The disparity jumps to seven times more likely if only selective serotonin reuptake inhibitors (SSRIs) are considered.
The new microrobots, made of gold and polypyrrole, can function in salty broths, blood, and other liquids. They may be useful for fundamental studies, manufacturing small devices, or minimally invasive surgery, according to the researchers.
Scientists have developed a chimeric receptor in rice cells that enables the switch on of disease-resistance machinery when exposed to brassinolide, a potent growth-promoting hormone. This breakthrough technique offers a promising approach to understanding plant signaling hormones and receptors.
Researchers at Johns Hopkins Medicine have discovered a compound called C75 that rapidly turns off appetite in mice, causing significant weight loss. The substance works by blocking the production of neuropeptide Y, a key hormone involved in appetite regulation.
Zebrafish have revolutionized the study of brain development, revealing new genes that control the formation of nerve cells and the backbone. This breakthrough has significant implications for understanding human diseases such as Parkinson's, Alzheimer's, and spina bifida, which may be linked to incomplete embryonic development.
A woman's personal search for medical research information led her to a cure for infertility and miscarriages. The proposal of an online archive for all biomedical research would give free access to latest medical findings, benefiting patients and scientists alike.
The National Library of Medicine is providing $102,000 to the Medical Library Association to strengthen programs for recruiting minorities into medical librarianship and increasing scholarship opportunities. The goal is to improve diversity in health sciences librarianship by attracting more minority applicants.
Researchers argue that online retailers focus too much on site hits and not enough on customer behavior patterns. By analyzing these patterns, retailers can identify frequent shoppers and target their marketing efforts more effectively to increase sales.
Researchers at the University of Pennsylvania School Medicine have discovered that the transforming growth factor-beta protein stimulates the development of sclerosis in the kidneys, leading to renal failure in diabetic mice. By neutralizing this protein, the study suggests that kidney disease in diabetes can be prevented.
A computer simulation, known as a cyberkid, was used to study how children's problem-solving behavior changes across ages. The study found that 7-year-olds' thinking improves in strategy selection as they grow towards adulthood.
A new study suggests that proteins alphav-beta3 and leukemia inhibitory factor (LIF) may serve as biomarkers for identifying women with endometriosis-related infertility. The research found a marked reduction in embryo implantation in mice injected with peritoneal fluid from infertile women with endometriosis.