Researchers at Johns Hopkins Oncology Center discovered a genetic alteration in tumor samples that predicts patient response to chemotherapy. The methyl-guanine-DNA methyltransferase (MGMT) gene was found to be altered in 19 patients, resulting in better responses to chemotherapy and increased long-term survival.
Scientists at Virginia Tech have discovered a crucial mechanism behind the growth of calcium carbonate crystals, which help remove carbon dioxide from the atmosphere. The research could lead to novel materials with unique properties for medical and high-tech applications.
Astronomers using Chandra X-ray Observatory have discovered that protostars, the youngest stage of star formation, are marked by powerful X-rays from plasma ten times hotter and 100 to 100,000 times brighter than our Sun's flares. This has provided the closest look yet at the youngest stars in the Universe.
A study published in 1998 found that candidates received an average of 2.33% more votes when their names appeared first on the ballots. In Florida, Bush's name at the top of the ballot likely contributed to his win, particularly with less-than-1,000-vote difference between Gore and Bush.
A 52-week study found that patients treated with 6-12 mg of rivastigmine daily showed significantly better cognitive function than those on placebo or lower doses. The treatment reduced cognitive decline and improved outcomes in patients with mild to moderate Alzheimer's disease.
Sidney Drell, 74, has been honored with the Enrico Fermi Award for his work on arms control and particle physics. The award recognizes his pioneering research in quantum electrodynamics and his technical contributions to national security issues.
Early results from 19 patients treated in the Boston clinical trial show that Endostatin is safe and well-tolerated in high doses without any evidence of toxicity. Extended periods of stable disease and minor responses have been demonstrated, but further study is needed to determine its long-term effectiveness.