A community-based therapeutic care component is being touted as a more effective and cost-efficient way to treat malnutrition during famine. The strategy aims to improve coverage, provide socioeconomic benefits, and reduce death rates from starvation.
The study found that exisulind significantly suppressed the rise in PSA levels compared to placebo, especially in high-risk patients. Exisulind therapy also lengthened the median PSA doubling time, suggesting a delay in disease progression.
A recent Wistar Institute study identifies an enzyme that modifies histones to activate specific genes in yeast. This discovery supports the 'histone code' theory, suggesting a complex interplay among histone modifications controls gene activity.
A UK population study found that an estimated 3.1% of adults aged 45 and older had definite or probable heart failure, highlighting the need for accurate diagnosis and targeted screening to alleviate symptoms and improve prognosis.
A study published in Science identified two genes, WNK1 and WNK4, that cause pseudohypoaldosteronism type II (PHAII), a disorder leading to hypertension. The researchers found that the mutated genes are overexpressed in affected family members, leading to increased salt reabsorption and blood pressure.
A recent trial found that WHO short-course chemotherapy was as effective as traditional Russian treatments in curing patients with tuberculosis. However, the results highlight the challenges of implementing changes in a healthcare system with entrenched cultural and structural barriers.
Researchers measured entropic forces exerted by rod-shaped viruses on particles in water, revealing additional effects of flexibility. The findings suggest that flexible viruses can effectively occupy more space, driving rearrangements in the system and increasing attraction between spheres.
Research suggests centromeric DNA and histones evolve rapidly, influencing species compatibility. Continuous evolution of centromeric histones may be driving adaptation to changing DNA sequences, contributing to the 'centromere paradox' and species sterility.
A new gene study reveals that early land plants and fungi evolved much earlier than thought, around 700-1300 million years ago. These organisms likely played a crucial role in changing the Earth's climate by increasing oxygen levels and decreasing carbon dioxide.
A study found that genetic traits from crops can persist in weeds for generations, potentially leading to hardy and hard-to-kill weeds. This raises concerns about the long-term impact of transgenic crops on weed populations.
Researchers Shiv Grewal and colleagues found that histone H3 variants are linked to gene expression and chromosomal structure. The study suggests a 'histone code' model for organizing the genome into active and silent regions.
Researchers at Clemson University are testing 15 houses with hurricane-resistant retrofits to determine their effectiveness. The study aims to provide more accurate estimates of retrofit costs and benefits, helping homeowners decide whether the expense is worth it.
A UK study found that childhood maltreatment and revictimisation of children and women are common problems. Abusive experiences co-occurred in both childhood and adulthood, with repetition and severity of childhood abuse independently associated with specific types of adult revictimisation.
The National Science Foundation is awarding $53 million to build a distributed terascale facility, supporting research in storm prediction, combustion engines and biology. The project will create a unique national resource for high-performance computing, connecting researchers across the US.
Researchers at Thomas Jefferson University have identified a novel photopigment in the human eye that regulates melatonin production, which plays a vital role in the body's circadian rhythms. Exposure to blue light has been found to be most effective in controlling melatonin levels.
Researchers at Virginia Tech have demonstrated improved fuel cell materials and systems, enabling operation at higher temperatures. The team will receive $2 million in grants to develop next-generation polymer electrolyte membranes and membrane electrode assemblies.
Research suggests that telomere shortening is associated with atherosclerosis, potentially linking it to premature ageing. Patients with severe coronary artery disease showed shorter telomeres compared to healthy controls, indicating accelerated cellular ageing.
A new computer-simulation tool developed at Purdue University has shown that a pre-cooling technique can reduce electricity costs for commercial buildings by as much as 41 percent during the hottest summer months. The tool takes into account factors like utility rates and climate to tailor the best strategy for individual buildings.
A team of researchers, led by George Cybenko and Sue McGrath, are developing a mobile agent-based system to monitor bone loss in astronauts during extended space missions. The system will analyze data on urinary calcium, diet, exercise, atmospheric conditions, and medical history to provide timely feedback and prevent bone loss.
Astronomers have observed a web-like structure in space using NASA's FUSE satellite, confirming theoretical models of how matter condensed into galaxies. The helium traces the universe's architecture back to very early times, shedding light on its re-energization by quasars and star birth.