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Science News for March 14, 2002


Adult human breast stem cell candidate found

Researchers have successfully established a cell line that functions like adult human mammary stem cells, opening up new avenues for studying breast cancer and tissue regeneration. The discovery was made by Dr. Ole William Petersen and colleagues from the University of Copenhagen and Lawrence Berkeley National Laboratory.

SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateMar 14, 2002

Technophobes may be right after all

Recent research in social informatics reveals that information and communication technologies often have unintended outcomes, such as harming group communications and exacerbating social differences. The studies highlighted the need for frameworks to expose value conflicts embedded in ICT design, but these are not widely practiced.

SourcePenn State·JournalAnnual Review of Information Science and Technology·DateMar 14, 2002

Ovarian carcinoma, ethnicity, and survival

Research found that African-American women with ovarian cancer are at a 30% increased risk of death from any cause compared to Caucasian women. The study also revealed significant differences in tumor stage, lymph node involvement, and surgery rates between the two ethnic groups. Median survival times were also shorter for African-Amer...

SourceWiley·JournalCancer·DateMar 14, 2002

Enzyme once thought harmful to Alzheimer’s patients now appears key to future treatment

A new study suggests that galanin, previously thought to be detrimental to Alzheimer's patients, may actually enhance acetylcholine release from remaining cholinergic basal forebrain neurons. This compensatory role could delay disease progression and inform the development of galanin antagonists as a potential treatment option.

SourceAmerican Physiological Society·JournalJournal of Neurophysiology·DateMar 14, 2002

Ace inhibitors could slow muscle decline

Researchers found that continuous ACE inhibitor users had a lower average decline in muscle strength and walking speed compared to intermittent users of other antihypertensive drugs. The study suggests that ACE inhibitors could be used to slow physical decline in elderly people without congestive heart failure.

SourceThe Lancet_DELETED·JournalThe Lancet·DateMar 14, 2002

Going beyond the genome

Researchers successfully determined the subcellular localization of over 2700 yeast proteins using a high-throughput method. By predicting the localization of all 6100 yeast proteins, Dr. Snyder and colleagues provided insight into nearly half of previously uncharacterized yeast proteins.

SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateMar 14, 2002