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Science News for February 15, 2003


Keeping blood pressure in check

A study found that mice deficient in RGS2, a regulatory protein, exhibited persistent vessel constriction and strongly hypertensive effects. This suggests that abnormally prolonged GPCR signaling may contribute to the onset of hypertension.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateFeb 15, 2003

JCI Table of Contents, February 14, 2003

Researchers found that RGS2-deficient mice developed strongly hypertensive conditions and persistent vessel constriction due to prolonged GPCR signaling. Genetic defects affecting RGS2 function may also contribute to hypertension in humans, according to findings published in the Journal of Clinical Investigation.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateFeb 15, 2003

Laser-pulse technique could aid drug design

A new laser-based technique could aid in drug design and testing for various neurological disorders, enabling the discovery of compounds to block cocaine poisoning effects. The technique allows researchers to study signal transmission between cells and identify potential therapeutic agents.

Opening the ‘black box’: Scientists gain new tools to learn about the near-shore environment

Researchers at UC Santa Barbara have developed new tools to study the near-shore environment, including remote sensing and genetic analysis. By analyzing chemical signals in growing skeletons and genetic differences among populations, scientists can track the movement of marine animals and understand barriers to dispersal.

SourceUniversity of California - Santa Barbara·JournalFrontiers in Ecology and the Environment·DateFeb 15, 2003