The HHS research plan aims to improve understanding of autoimmune diseases through genetic and environmental factor studies. The plan also calls for developing new treatments and diagnostics, as well as public education campaigns.
Researchers at Johns Hopkins Lupus Center and Kimmel Cancer Center found that high-dose intravenous cyclophosphamide can lead to complete responses and partial responses in lupus patients who failed standard therapy. The treatment also had fewer side effects compared to traditional treatments.
Bazer and Roberts identified proteins and mechanisms that regulate embryo development, fetal growth, and immune competence. Their research has clarified the biological mystery of signaling between embryo and mother to establish and maintain pregnancy in mammals.
A new method called GFT NMR increases data collection speed by orders of magnitude while increasing accuracy, potentially revolutionizing protein structure determination. This breakthrough could enable scientists to harness the power of latest NMR machines and cryogenic probes.
Researchers have discovered a genetic mutation in the DKC1 gene that causes a rare, fatal X-linked recessive disease characterized by premature aging, bone marrow failure, and increased cancer risk. The study suggests that ribosome dysfunction, rather than telomerase impairment, is the primary cause of this syndrome.
A new study by the University of North Carolina at Chapel Hill found that socioeconomic factors do not equally impact child obesity rates among different ethnic groups. The research suggests that focusing on social and environmental factors can lead to more effective weight management, particularly in minority populations.
Rice University scientists develop a nanosensor that can precisely analyze chemical information, opening doors for new methods to examine single molecules. The technology has widespread applications in environmental science, chemistry and biosensing, with potential early detection of cancer.
The study found that whole-body 18F-FDG PET scanning resulted in a change in treatment plans for 55 patients, avoiding unnecessary irradiation and treatment costs. PET scans also detected previously undiagnosed distant metastases in some cases, sparing patients from futile radiation therapy.
A new study by Dee W. Edington, Ph.D., of the University of Michigan found that individuals with obesity incur significantly higher medical costs than those with normal weight, with average annual costs rising from $2,225 to $3,753 for obese individuals. The economic burden of obesity is estimated to be substantial, with conservative e...
A recent study by Whitaker investigator Phil Bayly and his collaborators tested four brands of headgear, finding that they failed to dampen the impact of heading a soccer ball. The researchers used pressure sensors and metal mannequin heads to simulate heading at different speeds, revealing that only the fastest speed eased the impact.
A recent study found that gyms in western Oregon fail to meet ADA guidelines for accessibility, with pathways and customer service areas being the most non-compliant. The researchers offer specific recommendations for improvement, available online.
Molecular signals play a critical role in separating the lymphatic system from the circulatory system during fetal development. The study sheds light on the mechanisms behind this separation and its potential therapeutic applications, including influencing blood vessel growth and tumor treatment.