Add BrightSurf on Google Email

Science News for November 14, 2003


JCI Table of Contents, November 14, 2003

Two independent studies successfully selected and expanded gene-corrected human stem cells using a novel drug-resistance gene. This breakthrough may be useful in human clinical trials of gene therapy for bone marrow transplantation settings. Additionally, upregulation of Irs2 promotes beta cell growth, survival, and insulin secretion, ...

SourceJCI Journals·JournalJournal of Clinical Investigation·DateNov 14, 2003

Epilepsy at the movies

A study analyzing 62 movies across four continents found that epilepsy is often stereotyped, with males shown as violent and females as exotic and vulnerable. The dramatic potential of seizures may contribute to these portrayals.

SourceThe Lancet_DELETED·JournalThe Lancet Neurology·DateNov 14, 2003

Stem cell gene therapy: selecting only the best

Researchers successfully transferred and expressed MGMT into relatively few hematopoietic stem cells using a lentivirus vector, enabling gene-corrected cells to repopulate the hematopoietic compartment. This breakthrough has significant implications for human clinical trials of gene therapy in bone marrow transplantation settings.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateNov 14, 2003