A novel coronavirus, HCoV-NL63, is strongly associated with croup in children under three years old. The study found that 43% of patients with high viral load and no co-infection had croup, compared to 6% of those without the virus.
Children in southern Italy face a constellation of risks including high school dropout rates and low youth employment. The region also struggles with low vaccination uptake rates, leaving kids vulnerable to preventable diseases.
Researchers demonstrated that birds can be trained to respond to a magnetic direction and found that the ability to orient with magnetic cues is present in an ancient avian lineage. The new approach uses a social stimulus, unlike most previous attempts which relied on food rewards.
A new project in Australia is exploring the economic benefits of treating depression in employees. The WORC Project has surveyed 80,000 employees and found that treating depression can recoup $338 per employee per year, improving morale and reducing costs associated with absenteeism and work under-productivity.
Researchers found that Bell 206 helicopters with crash-resistant fuel systems had fewer post-crash fires than Aerospatial-350 helicopters without the system. The study suggests that stricter regulations and technology could improve civilian helicopter safety.
Researchers develop new method to detect sequestered malaria parasites in red blood cells. The study found that patients with severe malaria have six times higher parasite burden than those without severe symptoms.
Scientists have devised a new technique for creating human stem cells by fusing somatic cells with embryonic stem cells. The hybrid cells exhibit characteristics of human embryonic stem cells and can be induced to mature into various specialized cell types. However, technical hurdles remain before this method can be widely adopted.
Researchers studied over 13,000 people from five diverse sites to investigate dementia incidence. The study found no convincing evidence of variation in dementia incidence across sites or age groups, challenging previous proposals for public health policy.
In a study published in Nature Neuroscience, researchers found that monkeys overwhelmingly preferred to gamble by looking at the 'risky' target, even when it yielded smaller rewards. The neurons in the posterior cingulate cortex of the brain were found to be signaling the monkeys' subjective valuation of the target.
New study reveals that only about two-thirds of phase I clinical trial data were published within 7.5 years, highlighting the need for improvement in data dissemination. Lack of time and author relocation were cited as major obstacles to publication.
ERDITI, a collaboration between pharmaceutical companies and academic researchers, aims to repurpose 'abandoned' compounds for rare diseases. The initiative, launched by Alain Fischer, could lead to discoveries of effective treatments and profitable new drugs.
Researchers studied fruit flies' gap-climbing behavior, revealing three motor programs and complex motor patterns composed of behavioral subunits. Flies adapt and improve their movements to traverse gaps beyond their body size.
A comprehensive analysis of gene expression revealed that 650 genes differ between normal individuals and patients with ulcerative colitis or Crohn disease. Down-regulation, rather than up-regulation, was the prevailing pattern found in both diseases.
Researchers found that women with ovarian cancer were more likely to present to physicians with abdominal swelling or pelvic pain up to 12 months before diagnosis. Diagnostic testing showed only a minority of patients received necessary tests, highlighting the need for earlier detection.
Researchers found that exercising regularly, eating a high-quality diet and maintaining a normal weight can reduce the risk of periodontitis by up to 40%. These healthy behaviors also contribute to lowering diabetes risk factors. Regular monitoring and promotion of these habits by oral health professionals can help prevent gum disease.
Researchers discovered a new compound, LMP-420, that potently reduces activation of endothelial cells and inflammation in cerebral malaria. This finding offers a promising avenue for treating the condition, which has a high fatality rate despite existing treatments.
A Carnegie Mellon study found that people's emotional reactions to 9/11 persistently predict their perception of terrorism risk. Emotions like fear and anger affect optimism and pessimism about future attacks, while hindsight bias remains unchanged.
A new drug, CX717, has been shown to reverse the negative effects of sleep deprivation on brain activity and performance in monkeys. The drug targets AMPA receptors involved in cell-to-cell communication, restoring normal brain patterns and improving cognitive function.
Researchers at Carnegie Mellon University have discovered a novel mechanism called recursive splicing, which removes long introns by steadily paring them down in a predictable fashion and joining the remaining exons. This process has been conserved over tens of millions of years of insect evolution and is likely to occur in humans.
Researchers used genome synteny to study two closely related flower genes, AGAMOUS and PLENA, in Arabidopsis and Antirrhinum. They found that the genes originated from a single duplicated event around 125 million years ago.
Researchers discovered a potential biomarker, PKCi, which predicts outcome in non-serous ovarian cancer when combined with Cyclin E. High levels of the protein correspond to reduced survival rates.
A study found that weekly zinc supplements significantly reduced mortality rates among children under five years old, with a 85% decrease observed worldwide. Additionally, these supplements also showed promise in reducing pneumonia and diarrhea cases among infants younger than six months.
Researchers discovered that thermophilic bacteria have an abundance of disulfide bonds, which improve protein stability and boost heat-tolerance. The study identified a specific protein, protein disulfide oxidoreductase (PDO), playing a key role in forming these bonds.
Researchers found that bright-colored light can interfere with birds' magnetoreception, but in dim light, they still use a 'chemical compass' to migrate. The study reveals two distinct mechanisms of magnetoreceptors in birds: an inclination compass and a polarity-driven compass.
A recent MRI study has mapped 'silent' heart changes that remodel the heart, linking specific regional changes to early signs of trouble in the left ventricle. The study found that pumping function deteriorates as hearts increasingly change shape or remodel.
Researchers have found a way to get drugs past the blood-brain barrier to treat brain cancer. The compound JV-1-36, an antagonist of the hypothalamic growth hormone-releasing hormone, has shown promising results in treating malignant glioblastomas.
Researchers at Cornell University have developed a beetle-inspired switch that uses surface tension to create bonds, opening up possibilities for powerful adhesive bonding in arrays. The switch can be scaled down to the size of a micron and operates using water and electricity.
Researchers found that chimpanzees learn and adopt specific techniques to solve problems, demonstrating a form of culture. The study shows that chimpanzees have a tendency to conform to their group's norms, even when they know alternative methods exist.
Scientists have identified a new mechanism by which Listeria invades non-phagocytic cells, revealing similarities between phagocytosis and endocytosis. Researchers found that Listeria uses endocytosis to transport tagged proteins inside the cell.
A large study found no link between MS risk and birth order position, contradicting the hygiene hypothesis. In fact, individuals with MS tended to be born later in larger sibships than expected.
Researchers identified a new gene, BRIP1, associated with Fanconi anemia's hallmark chromosomal instability. The protein BACH1 helps DNA unwind for repair, and BRIP1 mutations disrupt this process.
A new statistical analysis of paroxetine trials reveals a significantly higher rate of suicide attempts among adults compared to placebo groups. The study confirms that all SSRIs increase suicidal tendencies in depressed adults, with increased intensity over time.
Researchers have found that few B cells are needed to trigger an effective T-cell immune response in certain cancers. A personalized vaccine used in a Phase I study resulted in an impressive 89% survival rate for patients with mantle cell lymphoma. The study paves the way for future vaccine use in other hematological cancers.
Researchers at NIA discover new gene FANCM linked to Fanconi anemia and increased cancer risk. The gene plays crucial role in DNA repair machinery, offering potential targets for treatment.
Researchers found chimpanzees learn by observation and adopt traditions through ape-to-ape transmission. Chimpanzee groups conform to established norms, even when alternative methods exist, suggesting an ancient origin for cultural conformity in non-human primates.
The competition focuses on exploring innovative research in physics and astronomy, with a focus on deep discoveries about reality and technological innovations. The 18 finalists will present their research papers at a special session in October, with nine prizes awarded based on outstanding merit.
Rensselaer researchers have developed a predictive modeling approach that can determine protein behavior for use in bioseparation applications. The model uses molecular information obtained from the protein structure to predict adsorption isotherm parameters and chromatographic behavior, replicating experimental results.
A study using tree-ring data reveals that severe droughts and low-flow conditions in one basin are unlikely to be offset by abundant streamflow in another. The research covers waterways from Arizona, Colorado, New Mexico, Utah, and Wyoming, spanning nearly 800 years.
The study found that both groups experienced reduced distress and improved cognitive function after writing, with the experimental group using more emotionally expressive language. Language analysis revealed differences in language use between the two groups, but some strategies showed consistent benefits for both conditions.
A large study of over 1000 women with BRCA1 and BRCA2 mutations found that weight loss is associated with a significant reduction in breast cancer risk. Women who lost at least 10 pounds between ages 18-40 had a 65% lower risk, while those who gained 10 pounds or more were at higher risk of developing the disease.
Researchers are working on a next-generation HPV vaccine that is both protective and therapeutic, which can be converted into powder for easier transport. The new vaccine aims to be less expensive than existing options like Cervarix and has shown promise in preventing HPV infection.
Researchers found direct decompressive surgery plus postoperative radiotherapy to be the most effective treatment, enabling 84% of patients to walk after treatment. This approach also reduced dependence on corticosteroids and opiod analgesics, showing significant benefits for patients with metastatic cancer.
A recent review of research suggests that playing violent video games can lead to increased aggressive behavior in children and adolescents. The study found that boys tend to play more violent video games than girls, and those who do play may be more vulnerable to the effects of exposure.
A research team led by Professors Lamb and Pugh has been awarded the Proctor Medal for their comprehensive analysis of molecular events underlying photoreceptor response to light. Their work enables straightforward use of the electroretinogram in analyzing deficits in various basic and clinical situations.
The RIT study found that museum imaging was output-driven and subjective, with a lack of standardized protocols. Key findings include the need for objective evaluation methods, improved color management, and more efficient workflows to enhance digital preservation.
Researchers at EPFL successfully demonstrate controlling the speed of light in an optical fiber, slowing it down by a factor of 3.6 and speeding it up to exceed the speed of light without violating relativity. This breakthrough has significant implications for optical computing and telecommunications.
A large study found that young children with medulloblastoma are at risk of impaired reading skills after radiation therapy, even if they receive lower doses. The greatest decline in IQ and reading skills occurred in patients younger than 7 years old.
Researchers at VCU's Massey Cancer Center have discovered a key enzyme involved in the spread of breast cancer cells. The study, published in the Journal of Biological Chemistry, suggests that sphingosine kinases are potential new targets for cancer therapy.
Researchers at Thomas Jefferson University have discovered a potential biomarker, GRK2, that can predict the severity of heart failure. Elevated levels of this enzyme in the blood are associated with more severe heart failure and may help identify patients who would benefit from specific treatments.
Researchers at Princeton University developed a new structure that can trap and redirect light, outperforming ordinary crystals in photonic circuits. This breakthrough could lead to the development of faster and more energy-efficient communication devices.
The National Safety Council has released new economic tools to measure the impact of health and safety initiatives in workplaces worldwide. These models, including Productivity Assessment Tool and ROHSEI, integrate risk assessments, cost-benefit ratios, and decision-making to motivate business leaders to improve safety performance.
A 15-year longitudinal study found that individuals diagnosed with minor depression were more likely to develop major depression, particularly among young adults (18-29 years old) and women. The study also revealed that cancer and other chronic illnesses did not increase the risk of developing major depression.
A new study reveals that despite progress in attracting women to science and engineering fields, they still face barriers to advancement, including unconscious bias and hostile campus climates. Institutions are responding with initiatives like mentoring programs and workshops to address these issues.
A new study by UCLA researchers reveals that heart-failure patients suffer from both physical and mental injuries, with brain damage impacting their ability to exercise. The findings emphasize the need for cardiologists to recognize this connection and develop therapies to prevent brain injury and boost brain function.
A recent study found that 71% of younger women with early-stage breast cancer discuss fertility-related information with healthcare professionals, while 86% discuss menopause. The research aims to educate women about fertility preservation methods and manage menopausal side-effects after treatment.
A UTD-led research team has produced strong, transparent carbon nanotube sheets with exceptional mechanical and electronic properties. These sheets have numerous applications, including organic light-emitting displays, low-noise electronic sensors, and artificial muscles.
Researchers at Emory University Health Sciences Center discovered the PCP pathway's role in shaping cochlea and hair cells. The study reveals that mutations in this pathway impact hearing and offers new insights into developing hearing restoration therapies.
A new study by the University of Washington's Evans School of Public Affairs found that federal funds intended for low-income schools are often diverted to affluent schools within the same district. The research documents how current rules allow taxpayer money meant to help overcome poverty to be shifted to wealthier neighborhoods.
A large body of evidence highlights barriers to increasing female faculty numbers, including lack of encouragement, confidence, and role models. Specific strategies, such as speed mentoring and ADEPT tool kit, are provided to address these issues.
Researchers at Penn State have developed a new microprinting technique called microdisplacement printing, which enables precise placement of molecules during nanoscale component fabrication. This method relaxes requirements for positioning stamps used to apply consecutive patterns with different molecular inks.