Women with the CYP2D6 genetic variant were more likely to experience breast cancer recurrence when treated with tamoxifen. Researchers also found that this group was less likely to suffer from hot flashes, which may predict the gene variation.
Researchers at Gladstone Institutes have made a breakthrough discovery about the role of miRNA-1 in the early stages of heart development. They found that miR-1 helps determine heart progenitor cells and maintain them until later embryonic stages, which could lead to new strategies for cardiac regenerative medicine.
Riboswitches are RNA elements that control gene expression in essential metabolic pathways. Researchers at Yale University have identified pyrithiamine as a toxic compound that disrupts these pathways, leading to the development of new antibiotics.
A study confirms that rice research has contributed significantly to poverty reduction in China and India. The research shows that improved rice varieties can increase farmers' income, lower food prices, and boost demand for labor, ultimately lifting millions out of poverty.
Aplysia sea slugs use a system to mix and release chemicals, including L-lysine, L-arginine, and an enzyme protein called escapin, to defend against predators. The secretion stimulates feeding behaviors in some animals but deters it in others, and may also have antimicrobial properties.
A Mayo Clinic study found that women with a genetic change in the CYP2D6 enzyme are at higher risk of breast cancer relapse when treated with tamoxifen. This genetic variation can also reduce the development of hot flashes, a common side effect of tamoxifen treatment.
A new study reveals that reliable resources like salmon, high population densities, and the defense of territories were crucial for the development of marked inequality in North America. Conversely, Australian Aboriginal societies on the tropical northern coast exhibited 'transient inequality' due to polygyny and high resource availabi...
A recent study found that traditional risk-factor scoring misses one-third of women vulnerable to coronary heart disease, highlighting the need for additional screening methods. Cardiac CT scans are recommended for certain groups of women based on their Framingham Risk Estimate and calcium scores.
The CHIKYU drillship, operated by JAMSTEC, has completed its first coring operations in the ocean. Two piston cores, 50 meters and 70 meters long, were retrieved from 1,200-meter water depths, revealing olive-grey diatomecious mud with ash layers and potentially absorbing CO2 density levels.
Researchers found that cancer cells can signal surrounding tissue cells to alter their molecular composition, promoting tumor growth and proliferation. The study suggests that cell mutations that promote cancer progression may arise in non-cancerous cells, indicating a need for broader anti-tumor therapies.
A new EU project is focused on developing cheaper, smaller ferroelectric films for use in microwave communication devices. These films have high dielectric permittivity and can be used to create voltage-controlled capacitors and tuneable microwave components.