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Science News for December 27, 2005


Medication reduces risk of heart irregularities after cardiac surgery

A recent trial found that a 13-day perioperative course of oral amiodarone significantly reduced the incidence of atrial tachyarrhythmias after cardiac surgery, particularly in older patients and those undergoing valve surgery. This effective therapy also showed promise in reducing hospital stay and associated healthcare costs.

SourceJAMA Network·JournalJAMA·DateDec 27, 2005

Having sibling with cardiovascular disease associated with higher CVD risk

A recent study by Joanne M. Murabito and colleagues found that having a sibling with cardiovascular disease increases the risk of developing CVD, even after adjusting for traditional risk factors. The research analyzed data from over 4,500 participants and found a 55% increased risk for incident CVD in those with a sibling CVD history.

SourceJAMA Network·JournalJAMA·DateDec 27, 2005

Flexible drug dosing produces less side-effects in people with epilepsy

The study found that flexible drug dosing permitted patients to remain on the medication longer due to fewer side-effects, while also showing a significant clinical advantage in treating patients with epilepsy. This approach balances efficacy and tolerability, providing more realistic data on antiepileptic drugs.

SourceBlackwell Publishing Ltd.·JournalEpilepsia·DateDec 27, 2005
CalDigit TS4 Thunderbolt 4 Dock

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Natural compound from 'pond scum' shows potential activity against Alzheimer's

A newly isolated compound, nostocarboline, has been shown to be a potent inhibitor of cholinesterase, a brain chemical linked to Alzheimer's disease progression. Its potency is comparable to an existing cholinesterase inhibitor, and it holds promise as a potential treatment for mild to moderate forms of the disease.

SourceAmerican Chemical Society·JournalJournal of Natural Products·DateDec 27, 2005

Dwarfs commanded respect in ancient Egypt

A study of ancient Egyptian remains and art reveals that dwarfs were highly respected and integrated into society. Elite dwarfs held important positions, while ordinary ones specialized in various occupations, suggesting a positive image of short people in ancient Egypt.

SourceWiley·JournalAmerican Journal of Medical Genetics·DateDec 27, 2005

UCSD researchers state vitamin D needed to cut cancer risk

UCSD researchers found a strong association between vitamin D deficiency and higher rates of colon, breast, and ovarian cancers. They recommend increasing the public's intake of vitamin D3 to 1,000 IU/day to reduce cancer incidence, which could lead to thousands of premature deaths annually.

SourceUniversity of California - San Diego·JournalAmerican Journal of Public Health·DateDec 27, 2005

Misdosing common for powerful anti-clotting drugs

A study of nearly 30,000 patients found that 42 percent received doses outside the recommended range, with excess doses linked to increased risks of bleeding and mortality. The researchers suggest improving dosing accuracy could save lives and reduce healthcare costs.

SourceDuke University Medical Center·JournalJAMA·DateDec 27, 2005
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