A study published in the American Journal of Clinical Nutrition found that cola consumption is associated with lower bone mineral density in older women, regardless of age, menopausal status, or diet. This may be due to phosphoric acid's potential to promote calcium loss from bones.
An interdisciplinary team will investigate how environmental changes influence an organism's evolution and how the evolving organism affects the ecosystem. The study, led by UC Riverside's David Reznick, aims to understand eco-evolutionary feedback loops in guppy populations coexisting with Hart's killifish.
A recent study published in Injury Prevention calls for increased vigilance on car manufacturers' commitment to road safety initiatives. The research analyzed word frequency analysis of road safety documents from the Global Road Safety Partnership and found that commercial interests often conflict with evidence-based recommendations.
A UK researcher has won a major science prize for his work on the region of the brain that helps us hear someone in a noisy place. The researcher, Sam Irving, is studying how the brain adapts to hearing loss and uses feedback systems to compensate.
Researchers at Cambridge University have developed an effective new method to test cognitive decline in mice with Huntington's disease using an automated touch screen. The tool allows for minimal movement by the mouse and is less stressful, making it a valuable asset in studying neurological disorders.
The IVD is a long-term contraceptive designed as an alternative to vasectomy, blocking sperm by plugging the vas deferens. The new device aims to be more appealing than traditional methods, but reversibility studies in men are still unknown.
Doris Tsao's research has shown that specific regions in the monkey brain are dedicated to recognizing faces, with neurons responding strongly to human and monkey faces. Her findings suggest that each face-recognizing neuron is tuned to respond to specific facial characteristics, allowing for the reconstruction of any face.
The Alaska Tsunami Education Program aims to improve math and science skills in students, teaching them how to recognize tsunami signs and react accordingly. The program targets 16 villages, collaborating with local organizations and government agencies to develop workforce-applicable skills.
The European Union should make vaccination against the human papillomavirus (HPV) mandatory for all girls aged 11-12 years to prevent cervical cancer. The vaccine offers protection against HPV types 16 and 18, responsible for 70% of all cervical cancers.
A new protein, RELM-beta, has been identified as a key player in the connection between gut bacteria and inflammatory bowel disease. Research found that mice lacking this protein are protected from colitis induced by dextran sodium sulfate.
Coral reefs face severe threats from human activities, and current MPAs are often insufficient to protect biodiversity. A global network of MPAs with optimal size and isolation is necessary to conserve coral reefs.
Scientists have identified a crucial role of TPH2 protein in regulating serotonin levels, which may be linked to the development of depression and manic depression. The study suggests that variations in the TPH2 gene are associated with an increased risk of developing these psychiatric disorders.
Richard Horton states that Julio Frenk has technical competence and administrative skills for the role. He is considered a front-runner due to his vision for WHO's revitalisation as a global public-health agency.
The tropics are revealed as the Earth's most fruitful biodiversity spawning ground, with fossil data indicating a consistent pattern of extinction, origination, and immigration. The study suggests that human-caused extinctions in the tropics will have long-term consequences on global biodiversity.
NASA's Aqua and Jason satellites have observed a general warming of ocean temperatures and a rise in sea surface heights in the central and eastern Pacific along the equator, indicating El Niño development. The current El Niño signal is far less dramatic than that seen during the start of the last major El Niño episode in 1997-1998.
For the first time, astronomers have looked inside quasars and seen evidence of black holes. They measured the size of the accretion disk around a smaller area emitting X-rays, providing further confirmation that quasars are made up of super-massive black holes and heated disks.
A new workflow language, Martlet, enables the analysis of large datasets in a changing environment by adjusting to data requirements at runtime. This approach has potential for use in various e-Science applications and demonstrates how core computer science can be used to meet exciting challenges.
Researchers have identified Tcf3, a transcription factor that regulates skin stem cells, as a key repressor switch. Activating this gene can prevent skin stem cells from maturing into adult skin cells, potentially providing insights for lab-grown stem cells and therapies.
New data reinforce the safety profile of ENBREL, confirming its efficacy for up to 2.5 years with no significant increase in adverse events. The study also shows that patients who experience interruption in treatment can regain similar positive efficacy results after re-initiating therapy.
Researchers discovered a biochemical signaling pathway between blood platelets and monocytes that triggers production of Cox-2, an enzyme involved in heart attack, stroke, and other inflammatory diseases. This finding offers hope for developing new drugs to modify Cox-2 production and prevent or lessen the severity of these conditions.
A region of the human brain believed to be critical to intellectual abilities functions much like a digital computer, according to CU-Boulder Professor Randall O'Reilly. The prefrontal cortex and basal ganglia operate by turning electrical signals into binary states and flexibly manipulating them, similar to digital computers.
A new study reveals a molecular mechanism underlying bone marrow failure in X-linked human disease, dyskeratosis congenita. Telomere maintenance defects are caused by reduced telomerase RNA, contradicting previous hypotheses about ribosome biogenesis.
The Journal of Infectious Diseases has published a supplement offering current information on pandemic and seasonal influenza, featuring leading experts discussing research and recommendations. The article highlights key findings on disease surveillance, vaccine manufacturing, and public health response plans.
A new study reveals a common pathological process between frontotemporal dementia and amyotrophic lateral sclerosis (ALS), with misfolded protein TDP-43 identified as a key component. This discovery may lead to a better understanding of these devastating neurological diseases.
Cornell researchers have extended a top-down approach to analyze larger proteins containing over 2,000 amino acids, providing more efficient identification and revealing protein modifications. The new technique rivals the commonly used bottom-up approach, offering a complete picture of each protein and its modifications.
A new national strategy could utilize small, lightweight jets to reduce congestion at major airports. The simulation predicts that policy changes are necessary to streamline the system, including better coordination among airlines and infrastructure providers.
A Phase II trial of Revlimid found that over 75% of MDS patients reduced their need for transfusions, with two-thirds completely freed from transfusions. In 45% of cases, no detectable cancer was found after treatment.
Research by Christina Ting Fong found that emotionally ambivalent workers perform better on creativity tasks, as they interpret mixed emotions as a signal to draw upon creative thinking abilities. Managers can leverage this by maintaining odd working environments, similar to companies like IDEO and Disney.
Researchers found that smoking in cars can produce unsafe levels of secondhand tobacco smoke, posing a significant risk to children's health. The study measured concentrations rated 'hazardous' by the EPA, highlighting the need for smoke-free environments for children both in cars and homes.
Penn researchers identify misfolded TDP-43 as common pathologic protein linking frontotemporal dementia and amyotrophic lateral sclerosis, leading to new avenues of research into the relationship between the two disorders. The discovery has significant implications for developing effective treatments for these lethal diseases.
Researchers discover RELM-beta's role in IBD, finding it activates macrophages to produce pro-inflammatory factors. Additionally, antibodies against BP180 cause blister formation in mice by activating the classical complement pathway.
University of Alaska Fairbanks Professor Larry Duffy has been awarded a National Science Foundation grant to develop a new polar science education course. The two-year project will help increase students' and the public's understanding of polar science through an interdisciplinary approach.
Researchers have discovered that animals with altered cytoskeletal structures are less susceptible to alcohol's intoxicating effects. A team of Italian researchers found mice lacking a gene that influences the cellular skeleton became less sensitive to ethanol exposure, leading to increased drinking and reduced neurological damage.
A study by McGill University Health Centre researchers finds that sperm banks are unpopular with patients due to lack of accurate information and improved doctor-patient communication. Quebecers are less likely to choose sperm banking than patients of immigrant descent.
Scientists successfully teleported the state of a light pulse to an ensemble of 10^12 atoms, marking the first transfer between objects of different nature. The experiment has significant implications for quantum computing and quantum cryptography.
A University of Illinois study explores how abused women decide on child custody arrangements, revealing the complex interplay between fear, practical considerations, and family ideology. The research highlights the need for tailored interventions to address the unique needs of parents with histories of violence.
A molecule called TBK-1 helps keep cancer cells alive, and blocking it may be a promising approach to treating cancer. Researchers at UT Southwestern Medical Center found that TBK-1 is essential for cancer cell survival, even though its normal function is in the immune response.
Researchers have identified a gene mutation in fruit flies that regulates sensitivity to alcohol. The study found that some fruit flies were more resistant to alcohol's sedative effects, and the researchers isolated the specific genetic mutation responsible.
Researchers found that microRNA-9a regulates neural development in fruit flies, controlling the precise production of sensory organ precursor cells. mir-9a also represses transcription factor Senseless to regulate neuronal precursor cell numbers in Drosophila and potentially in mammalian neurogenesis.
Researchers found that nearly all tumor cells in the bone marrow of early-stage breast cancer patients have a putative breast cancer stem cell phenotype, increasing the risk of disease progression. This study provides evidence that these stem cells may be responsible for metastases and has significant implications for cancer treatment.
A new UCLA study shows that chemotherapy causes persistent changes in brain function, leading to cognitive symptoms like forgetfulness and confusion. PET scans reveal a link between chemo-brain symptoms and lower brain metabolism, suggesting that monitoring brain activity could help prevent these effects.
Purdue researchers use new mass spectrometry technique to create high-resolution images of biological samples, enabling precise cancer detection and tissue removal. The technology has far-reaching applications in medicine, including the detection of diseases like cancer.
A new study published in Pediatrics found that consuming 100 percent fruit juices is not associated with overweight status among preschool children. The analysis of the largest government database on food consumption suggests that preschoolers are consuming appropriate amounts of juice, averaging 4.7 ounces per day.
Researchers at UCSF discover spineless gene's role in controlling dendritic branching patterns in fruit fly neurons. The findings suggest the gene may convert primordial patterns for different neuron types, potentially contributing to neurological disorders like autism.
A study finds that the mutant huntingtin protein disrupts energy metabolism, leading to neurodegeneration in Huntington's disease. Researchers discovered that PGC-1a levels are lower in affected cells, suggesting a protective role for the protein.
A three-year project led by geologist Brandon Nuttall found that the deeper parts of Devonian black shales in Kentucky could store up to 28 billion tons of injected CO2. The analysis of 43 shale samples from recent drilled wells indicates that the area alone could sequester 6.2 billion tons of CO2.
A study found that misoprostol is an effective way to prevent postpartum hemorrhage in countries with limited hospital services. The drug significantly reduced the risk of acute postpartum hemorrhage and average blood loss, offering a cost-effective solution for resource-poor settings.
A Rutgers-led group has been awarded a $2.55 million grant to develop instructional materials that integrate mathematics and biology in high school courses. The project aims to close the gap between math and biology instruction by creating modules that address key topics such as gene mapping, population trends, and public health.
A recent study found that the tumor suppressor gene H-REV107-1 stimulates growth in non-small cell lung carcinomas via mitogenic signaling. In contrast to expected function, cytoplasmic localization of H-REV107-1 correlates with decreased patient survival.
Gary D. Thomas, a Raytheon engineer, has been honored by the USC Center for Systems and Software Engineering (CSSE) for his seminal contributions to systems and software cost models. His work on COCOMO, a widely used tool for estimating costs and time required for software development, has had a lasting impact on the field.
The University of Alaska Fairbanks study proposes four policy strategies to sustain people and the environment in a dramatically warming climate. The first strategy focuses on adaptability, while the second emphasizes biological diversity as a buffer from change.
A global study published in The Lancet found that over a quarter of women worldwide reported physical or sexual abuse by an intimate partner, with severe acts more common in traditional rural settings. Women's education and marital status did not explain these differences, suggesting other risk factors are at play.
Researchers have developed a laser-based technology that can rapidly detect and identify many types of bacteria, making it three times faster and one-tenth as expensive as current methods. A second innovation uses chlorine dioxide gas to kill pathogens on produce, offering a highly effective and efficient solution.
Researchers at the University of Chicago have made a groundbreaking discovery in air bubble behavior, revealing that they can tear apart instead of pinching off. This phenomenon has significant implications for our understanding of fluid dynamics and the equations that govern it.
The research team identified a single recessive gene, Rymv1, which confers resistance to the virus by blocking its interaction with the host protein. The discovery could lead to the development of resistant rice varieties, reducing yield losses and improving food security.
Researchers at Johns Hopkins Medicine have identified a critical protein player in cell communication, which controls calcium flow into cells. This finding sheds new light on the rare cognitive disorder Williams-Beuren syndrome, associated with overly social behavior and spatial learning defects.
Scientists have detected loops and rings of hot gas surrounding the supermassive black hole, indicating periodic eruptions that generate pressure waves and sound. The sound waves are found to be more discordant and complex than previously detected, with a range of frequencies below middle C.
A new study reveals that tropical regions are both a cradle and a museum of biodiversity, with many species originating in the tropics and spreading to higher latitudes. The research suggests that preserving tropical ecosystems is crucial for maintaining global biodiversity.
Researchers at Boston Children's Hospital have identified a novel pathway that influences the timing of nerve-cell production, favoring neuron over astrocyte formation. This discovery may provide insights into diseases such as Alzheimer's disease, schizophrenia, and autism.
A study published in The Lancet found that oral misoprostol significantly reduces maternal hemorrhage and postpartum blood loss in women giving birth in rural, developing communities. This life-saving treatment has the potential to prevent up to half of maternal deaths from pregnancy-related causes.