A study of 50 patients with treatment-resistant lupus found an overall 5-year survival rate of 84% after autologous hematopoietic stem cell transplantation (HSCT). The longest continuous duration of remission was 7.5 years, with a 2% treatment-related death rate.
A study of 208 patients treated at Bellevue Hospital from 1990 to 2003 found that most had minor injuries, but some suffered severe amputations or died. The researchers identified a pattern between economic downturns and increased subway accidents, suggesting that slowing down trains could reduce the severity of injuries.
Chronic oil pollution has been a long-standing problem along the Atlantic Coast in Brazil, Uruguay and Argentina. Researchers found that Magellanic penguins, appearing in high numbers among oiled seabirds, are particularly affected by the pollution.
Scientists at Tel Aviv University build a system to create plasma fireballs similar to natural ball lightning, providing insight into the phenomenon. Meanwhile, researchers at Purdue University simulate how to make liquids drip from an opening even without gravity's tug, potentially leading to new applications for printing and microsca...
Scientists at Berkeley Lab create porous scaffolding-like material that mimics nacre's structure, exhibiting four times greater strength than current materials. The composite could foster bone tissue regeneration and improve artificial joints.
Minister Gehrer addresses key challenges in European R&D, including the timing of the new Framework Programme and the need for a strategy to stimulate innovation. She also emphasizes the importance of reducing red tape and promoting entrepreneurship and risk-taking through life-long learning.
A recent study found that discontinuing antidepressant medication during pregnancy can lead to a higher risk of depression relapse compared to continuing treatment. The study, which enrolled 201 pregnant women, suggests that women taking antidepressants who anticipate pregnancy should discuss the risks and benefits with their doctors.
A study published by Northwestern Memorial HealthCare found that high-dose chemotherapy and autologous stem cell transplant can result in disease remission and improvement or salvage of residual organ function in the majority of patients with life-threatening lupus. The treatment's lower toxicity rate compared to previous studies may b...
Researchers found that timely diagnosis of diabetes improves blood pressure control, glucose management, and overall health outcomes. Studies also suggest that reengineering primary care practice through practice redesign may be necessary to substantially improve chronic illness care.
Researchers found that STAT1 expression was lower in SCCHN tumors than in normal tissue, and increasing STAT1 expression led to suppressed tumor growth. The study also suggests that STAT1 works as a tumor suppressor for SCCHN cells, but when its expression is lowered, SCCHN tumors grow.
Researchers found that people tend to use apologies and concessions in intimate relationships, while excuses are less effective. The study also revealed that the context of the situation influences the chosen strategy, with serious offenses generating additional apologies and concessions.
New research reveals the Drosophila homolog of the mammalian UNR protein as a co-factor required for SXL-mediated repression of msl-2 translation. This mechanism prevents dosage compensation in female cells, highlighting an essential role for the UNR protein in maintaining sex-specific regulation.
Research found no significant association between hospital case volume and short-term mortality after ovarian cancer surgery. However, patients treated by gynecologic oncologists had the best outcomes and lowest mortality rates. Long-term outcomes were slightly more favorable for high-volume hospitals, but this difference was modest.
A study in South Africa found that implementing a blood safety program, including education and targeted outreach, significantly reduced the prevalence of HIV-1 in blood donations. The program resulted in a 50% decrease in HIV-1 positivity rates over two years.
Researchers found that STAT1 is a critical survival pathway in head and neck cancer, with increased levels leading to diminished and dying cancer cells. Therapeutic strategies to restore its functioning may be beneficial for patients, potentially improving treatment outcomes and survival rates.
A new study using bone SPECT test shows that the test can identify patients with lower back pain who would benefit from facet joint injections, leading to significant pain reduction and cost savings. The test can help doctors avoid unnecessary injections in patients who may not respond well to them.
African remains found in Campeche, Mexico, provide earliest physical link between the African Diaspora and the New World. The discovery, dating back to the late-16th century, sheds light on the early transatlantic slave trade.
Researchers found that early identification of patients who would benefit from non-surgical treatment improved survival rates. The study, published in the Journal of Clinical Oncology, showed a significantly better cure rate when matching the right treatment to the patient's tumor biology.
Scientists found that RNAi machinery plays a role in maintaining telomere length by regulating retrotransposon transposition. Mutations in key components of the system increase telomere element transposition.
Researchers detected lower gray matter density in brains of patients with Type 1 diabetes, associated with poorer glycemic control and depression. The study opens up new approaches to understanding the central nervous system in diabetes.
The five-year data demonstrate long-term efficacy and reliability of MAL-PDT for treating superficial and nodular basal cell carcinomas, with superior cosmesis compared to cryotherapy. The treatment was found to be non-inferior to surgery in relation to initial response rates, but with significantly better cosmetic outcomes.
An undergraduate researcher at Williams College has discovered the specific mechanism mice use to enter torpor, a state that enables them to survive fasting periods. The study found that replacement of epinephrine and adrenaline in the peripheral nervous system determines whether an animal enters torpor.
University of Illinois researchers Gustavo Gioia and Pinaki Chakraborty explain the behavior, which was previously unknown. The findings provide a new way to calculate friction forces along rough walls.
Researchers use confocal laser scanning microscopy and Raman spectroscopy to analyze ancient microorganisms in Martian rocks, revealing insights into biochemistry and degradation over millions of years. The techniques allow scientists to view fossils in three dimensions, providing new evidence for the search for life on Mars.
A study on rural families in Michigan explores the challenges faced by wage-earning women due to economic restructuring, highlighting the importance of addressing child care needs and increasing access to secure employment with benefits. The research emphasizes the need for new education delivery modes to empower these populations.
In a study published in Biology Letters, researchers found that male monkeys of two species experience a 10% weight gain when their mates are pregnant. This gain is likely due to hormonal changes, including increased prolactin and estrogen levels. The study's findings could provide insights into human fathering behavior and motivate me...
Researchers have developed a new method of lie detection using brain MRI, which can accurately identify deception in 92% of cases. The test measures brain activity, eliminating the limitations of traditional polygraph tests.
A study published in JAMA found that pregnant women with major depression are at a high risk of relapse if they discontinue antidepressant medication. The research highlights the need for accurate information and treatment guidelines to help clinicians make informed decisions about managing depression during pregnancy.
The NYAS China Conference showcased groundbreaking research on chemical biology, infectious diseases, genomic medicine, and neuroscience. Experts discussed innovative approaches to drug development, disease treatment, and brain growth, highlighting the importance of global collaboration.
Researchers found that language affects perception in the right half of the visual field, but not in the left. The study suggests that linguistic differences can sharpen visual distinctions in the right visual field.
Researchers at UCSB discovered a genetic pathway that could lead to new treatments for ADPKD. The polycystin-1 protein plays a key role in the disease, and its inhibition may have beneficial effects. This finding opens up new avenues for drug development.
A new device called DLS-PM measures the quality of blood platelets, allowing for longer storage and improved matching with patients. This innovation has the potential to increase the availability of platelets globally, particularly in crisis situations.
Researchers identified a new gene associated with Charcot-Marie Tooth disease, a rare inherited neurological disorder. This discovery may lead to better understanding of how nerves function and improved diagnostic possibilities for CMT sufferers.
Biobullets, tiny microcapsules that release potassium chloride, have been developed to combat zebra mussels. The new method poses little threat to other marine animals and is faster than existing methods, making it a promising solution to the ongoing problem.
Scientists uncover the final steps of retrotransposon replication, revealing how they integrate into human genomes and contributing to genetic disease and genome expansion. The study sheds light on the mechanism behind the accumulation of millions of 'junk' genes.