Researchers found that atorvastatin increased circulating endothelial precursor production by 1.7 to 8-fold in SSc patients, improving Raynaud's phenomenon activity but symptoms generally returned to baseline after discontinuation.
A recent study found 14 cases of direct adverse events associated with pediatric spinal manipulation, including serious events like hemorrhage and paraplegia. The research team is now working on developing a more effective reporting system to collect data on outcomes, including harms.
Researchers have identified new biomarkers that correlate with patient response to anti-TNFá therapy, improving the treatment of spondylarthritis. The study found changes in synovial tissue features, such as macrophage and PMN cell changes, associated with disease activity and treatment effectiveness.
A recent study found that bacteria can utilize DNA as a critical food source, enabling them to outcompete other microbes and survive longer. The study identified eight genes necessary for this process, known as nutritional competence, which could have applications in medical research and the development of genetic antibiotics.
UT Southwestern researchers found that a Yersinia outer protein called YopJ cripples host enzymes, preventing the immune response and allowing the bacteria to survive. The study presents a new paradigm for how cells regulate signaling and could lead to a better understanding of host-pathogen interactions.
Researchers predict that braneworld black holes, created in the early universe, have survived and can be detected by observing gamma-ray bursts passing near them. The signature of these black holes could provide evidence for a fourth dimension of space.
Researchers observed eruptive activity at Northwest Rota-1 for three separate visits over two years, suggesting chronic eruptions. They used an underwater robot to observe explosive activity from 10 feet away, gaining clearer insights than possible on land.
Dental caries is a widespread and increasing problem globally, with 5 billion people affected. Forsyth researchers aim to develop a vaccine targeting bacterial accumulation on teeth, with initial focus on mucosal vaccines for young children.
The ITTO report reveals that sustainably managed tropical forests have expanded from 2.4 million acres in 1988 to at least 87 million acres in 2005. However, the majority of forest land being managed sustainably comprises less than 5% of total surveyed areas.
Carbon nanotubes have withstood pressures up to 40 gigapascals, making them ideal for nanoscale hydraulics and cylinders. The researchers discovered that nanotubes can perform similar functions at the scale of atoms and molecules, including extrusion processes.
Researchers used tree-ring records and gauged streamflows to reconstruct historic Colorado River streamflows, dating back to 1490. The reconstructions suggest that droughts more severe than the recent 100-year period occurred in the past, with at least eight droughts similar in severity to the 2000-2004 drought.
Researchers found that parasites can modulate immune responses and reduce inflammation in inflammatory bowel disease. The study suggests that improved hygiene may be responsible for the rise of IBD in developed societies.
Researchers at Duke University have reported a theoretical blueprint for an invisibility cloak made of metamaterials. The cloak can hide objects so well that observers are unaware of their presence, similar to how water flows around a smooth rock in a river. This technology has potential applications in wireless communications and acou...
Researchers have developed a new approach to target different diseases using short interfering RNA (siRNA) with tailored cellular properties. Human trials for siRNA-based anti-cancer and anti-viral treatments are currently underway in the USA and Europe, offering promising results.
A study by Saint Louis University found significant changes in brain activity after vagal nerve stimulation treatment began, continuing to evolve over 21 months. The treatment appears to induce long-lasting brain changes, with benefits lasting up to two years.
Researchers identified mutations in the AIP gene as the underlying cause of pituitary adenoma predisposition. The discovery provides molecular tools for efficient identification of predisposed individuals, potentially leading to earlier diagnosis and treatment of conditions like acromegaly and gigantism.
Researchers Harry Roberts and Bob Carney are studying the animals that live near oil and gas seeps in the Gulf, including bacteria that feed on hydrogen sulfide gas. They will use the Alvin submersible to take them down to the bottom of the Gulf, where they hope to discover new species and learn more about these unique communities.
NIST researchers create a microfluidics technique to isolate and pattern neuronal cells on surfaces, allowing for the study of cell development and behavior. This breakthrough enables a variety of cell-geometry experiments, such as measuring the maximum gap between lines that can be bridged by neural axons and dendrites.
Two surgical procedures, laparotomy and bowel resection, and peritoneal drainage, were compared in a multi-center randomized controlled trial. The study found that patient survival rates and major outcomes were virtually identical between the two procedures.
A study conducted by Yale University researchers found that Iraqi nurses require improved working conditions, equipment, and financial support to ensure the success of the healthcare system. The nurses also emphasized the importance of respect from physicians, administrators, and society at large.
Ignoring Indigenous communities' health experiences under current MDG policies puts them at risk of disappearing forever. The Lancet series highlights the importance of including Indigenous wisdom and rights in international health and medicine.
Researchers found that magnesiowüstite, a common mineral in the lower mantle, absorbs infrared light when compressed to extreme pressures. This suggests that radiation may not play a significant role in heat flow near Earth's core.
Phase 3 clinical trials demonstrate desvenlafaxine succinate's effectiveness in reducing depressive symptoms and improving quality of life for adult patients. The medication also showed promise in managing depression-related pain, highlighting its potential as a valuable treatment option.
Researchers found that defendants rated as 'stereotypically black' were sentenced to death at a rate of 57.5%, compared to 24.4% for those less stereotypically black, in cases involving white victims. However, this effect disappeared in 'black-on-black' capital cases.
A multicenter randomized controlled trial involving 117 premature infants found that laparotomy and bowel resection and peritoneal drainage surgical approaches have essentially the same major outcomes in terms of patient survival. The study ends three decades of speculation and debate over which approach is more effective.
The Lancet series highlights disparities in indigenous people's health worldwide, with lower life expectancy, higher rates of infectious diseases, and poor access to healthcare. Researchers are calling for greater respect and action to address these issues and preserve unique knowledge about ecosystems and medicines.
Research reveals that non-pathogenic bacteria from cow manure share antibiotic-resistance genes with multi-drug resistant Salmonella strains on the same farm. Ecology appears to play a major role in the spread of drug resistance, rather than therapeutic antibiotic use.
The study found that Aboriginal infants had more preventable deaths and higher disparities in death rates compared to non-Aboriginal peers. The researchers emphasize the need for effective maternal and infant services to address these disparities and promote long-term Aboriginal health and well-being.
NIST researchers have developed a more accurate method for measuring distillation curves, which are crucial for characterizing fuel composition and performance. The new approach eliminates uncertainties and systematic errors, enabling better correlation with thermodynamic theory used in modern fuels and engines.
NIST researchers have successfully grown gallium nitride alloy nanowires with intense ultraviolet and visible light emission. The wires' high light output and defect-free structure enable reliable room-temperature measurements, while their versatility makes them suitable for various devices, including sensors and transistors.
The latest Global Disease Burden study finds a 20% reduction in global disease burden, but HIV/AIDS and malaria increase death tolls, particularly in sub-Saharan Africa. Meanwhile, Eastern Europe experiences a 'striking reversal' in falling adult mortality rates without effective health monitoring.
Researchers found a 2-degree widening of the tropics, with subtropical deserts expanding into midlatitude regions. Midlatitude temperatures warmed by 1.5 degrees Fahrenheit over 26 years, suggesting a change in jet stream positions.
A recent Virginia study suggests that US schools should prioritize an early emphasis on science to boost the number of future scientific leaders. The research found that students who expected to pursue science careers were more likely to earn degrees in life sciences or physical sciences and engineering.
Recent research using genetic data analysis and simulation software challenges the common assumption that modern residents of a region are direct descendants of their earlier inhabitants. The study suggests that the Etruscan population may have been more diverse or socially elite, leading to little overlap with modern Tuscans.
Researchers found faster subtropical warming of the troposphere, moving jet streams poleward, which could widen tropical regions and alter rainfall patterns. This shift may reduce winter precipitation in southern Europe and Australia, as well as impact regional climate patterns.
A new study reveals that removing top predator species from kelp forests has a profound impact on the ecosystem, while organic coastal run-off has minimal effect. The research suggests California is on the right track with fishing limits to protect the delicate food chain.
The ESRC report reveals high demand for social science PhD holders in various sectors beyond academia. The study highlights the crucial importance of equipping UK social scientists with core research and professional skills.