The study found that positive pressure ventilation significantly reduced temperatures and smoke in corridors and stairwells, making them safer for occupants and responders. The experiment involved 11 NIST researchers and over 70 local staff, simulating real-world conditions to assess the effectiveness of PPV in multistory buildings.
A new grid computing system enables doctors to share high-resolution medical images quickly and securely across North America. This breakthrough improves diagnosis accuracy, allows for second opinions from specialists anywhere easily, and enhances monitoring of ongoing clinical research.
A study published in JCI found that overexpression of CaMKII altered sodium channel function, leading to increased susceptibility to ventricular tachyarrhythmias in mice. Additionally, proteasome composition differed between Crohn disease and ulcerative colitis, with CD showing increased degradation of an NF-kappa-B inhibitor.
Researchers found that mutations in LRRK2 protein stunt neuron growth and branching, leading to dopamine-producing neuron loss and disease progression. The study provides a useful animal model for studying PD and discovering new treatments.
Research published in Obesity shows that one-fourth of overweight, inactive children tested positive for sleep-disordered breathing. After three months of vigorous exercise, the number of children with sleep disorders was cut in half, and even those who exercised less saw an improvement on a pediatric sleep questionnaire.
In a groundbreaking pilot study, researchers at Duke University Medical Center found that children with egg allergies can build up their bodies' resistance to eggs by gradually consuming increased quantities over time. The study's findings show promising results for the development of a meaningful therapy for food allergy sufferers.
A study by Cornell Food & Brand Lab shows that we tend to overeat due to cues around us, such as plate size and distractions. By using smaller plates or limiting food options, individuals can make easier changes to control their eating habits.
Massachusetts General Hospital researchers have discovered a master cardiac stem cell capable of differentiating into three types of heart cells. This finding offers new prospects for drug discovery and genetically based models of human disease, as well as a novel strategy for the regeneration of cardiac muscle and associated structures.
Researchers uncover the secret recipe behind Hessian crucibles, a 500-year-old alchemists' lab kit component that was previously unknown to be used in their manufacture. The discovery sheds light on the skill and ingenuity of ancient craftsmen who exploited modern materials centuries before they were understood scientifically.
Scientists developed a comprehensive map of copy number variants (CNVs) in the human genome using advanced microarray technology and algorithmic tools. The study identified over 1,400 CNVs covering 12% of the genome, shedding light on genetic changes linked to diseases such as Alzheimer's and Parkinson's.
A team of scientists used high-energy X-rays to study the hydrophobic water gap, revealing its size and characteristics. The study provides new insights into protein folding and stability, which are crucial in biological systems.
Researchers at Yale University found that competitive female cyclists have reduced genital sensitivity. No negative effects were observed on sexual function or quality of life in the study's young, healthy participants.
A new study found bivalirudin, an anti-clotting agent, is equally effective as a combination of injectable blood thinners in treating acute coronary syndromes, resulting in fewer cases of major bleeding. The medication reduced the risk of mortality by reducing bleeding complications.
Researchers at Yale University have found a gene variant that increases the risk of developing aggressive 'wet' age-related macular degeneration, the most common cause of blindness in people over 50. The study found a single nucleotide polymorphism (SNP) in the HTRA1 gene on chromosome 10 associated with greatly increased risk of wet AMD.
Researchers from Delft University of Technology successfully measured transport through a single atom in a transistor, offering insights into the behaviour of dopant atoms in silicon. The individual behaviour of dopant atoms is a stumbling block to further miniaturisation of electronics.
A type of stem cell has been identified that gives rise to both myocardial cells and vascular smooth muscle cells, challenging previous notions of how the heart develops. This discovery could lead to the development of new treatments for congenital heart defects and damage caused by heart attacks.
The University of Manchester will develop innovative new counter-terrorism technologies using £multi-million pounds in funding from the Home Office. The project aims to improve detection, identification and decontamination of chemical, biological and radiological materials.
A multicenter study found that measuring fetal oxygen levels does not affect the rate of Caesarean section or the health of newborn babies. Researchers tested whether knowing fetal blood-oxygen levels made a difference in the rate of Caesarean section or condition of the newborn infant.
Scientists have created a prototype carbon nanotube knife that could revolutionize cell biology by enabling precise cuts and 3D images of cells. The device, which stretches between two electrochemically sharpened tungsten needles, has shown promising results in mechanical strength tests.
Researchers found that continuous fetal oxygen saturation monitoring had no significant effect on Caesarean delivery rates for both normal and abnormal fetal heart rates. The study enrolled over 5000 women across 14 hospitals, with no statistically meaningful differences in Caesarean deliveries between the groups.
The University of Manchester won a $500,000 prize for its innovative approach to knowledge transfer and collaboration with industry. The university's Faculty of Engineering and Physical Sciences was awarded the grant to support concept studies, short projects, and an incubator scheme for companies.
Joel Rosenbaum's research has made significant advances in understanding the assembly, maintenance and function of cilia and flagella, leading to a deeper understanding of polycystic kidney disease (PKD). His work has also revealed the importance of primary non-motile cilia in signaling pathways.
A new model developed by researchers at the University of California - Santa Barbara predicts the survival of coral reefs based on their shape and size. The study found that table corals with broad flat tops are more susceptible to strong wave forces, while bushy or mounded corals are less vulnerable.
New research reveals that at least 10% of human genes have variations in the number of DNA copies, influencing gene activity and function. This discovery changes the way scientists think about genetic diseases and human evolution.
Researchers discover master cardiac stem cells capable of producing all three major tissues of the mammalian heart. The findings challenge traditional understanding of heart development and may hold promise for cardiac stem cell therapies.
A new study aims to uncover the causes of the testicular cancer increase among 15-35 year old Caucasian men. The research will examine environmental hormone disruptors and genetic susceptibility as potential risk factors.
Researchers found CaMKII alters Na+ channel function, leading to VTs in mice with heart failure. Overexpression of CaMKII increased susceptibility to life-threatening arrhythmias.
Researchers at Yale School of Medicine found that genetic factors contribute significantly to the development of retinopathy of prematurity (ROP), with 70% of the contribution attributed to genetics. The study identified gestational age and supplemental oxygen as significant independent contributing factors for ROP.
Researchers have demonstrated a central role for zinc in modulating signaling among neurons, shedding light on its presence in free ion pools. The findings show that manipulating synaptic zinc levels can affect neuronal action, highlighting the complexity of potential therapeutic interventions.
Research by Alberto Cordero found that 76% of workers over 60 are overweight or obese, leading to increased mortality and reduced productivity. The study also showed a strong link between metabolic syndrome, arterial hypertension, and cardiovascular risk factors.
Researchers at Pacific Northwest National Laboratory have discovered 176 proteins associated with plague virulence, offering promising leads for improved disease detection and treatment. The study's findings may also guide the development of new vaccines and therapies to combat the deadly disease.