The L'Oreal USA Fellowships recognize women scientists conducting innovative research across various disciplines, including neuroscience, oceanography, and aerospace engineering. The recipients will receive $40,000 for independent scientific research and participate in professional development workshops.
A new study identifies CUL7 E3 ubiquitin ligase as a key regulator of protein degradation linked to cellular senescence. The researchers found that the enzyme targets insulin receptor substrate 1 (IRS-1) for degradation, leading to oncogene-induced senescence.
A unique HIV vaccine formulation has been shown to induce strong and balanced immune responses in healthy human volunteers. The combination approach used in the study achieved high titer antibodies that recognized a diverse group of HIV envelope proteins, providing promising results for future efforts to optimize HIV vaccine formulations.
Research by University of Texas M. D. Anderson Cancer Center scientists shows stabilizing p53 can protect mutated versions that promote cancer cell spread. The p53 gene's normal role is to halt defective cell division and force self-destruction.
Researchers documented the arms race within viral and host genes, showing viruses shuffling DNA to evade RNA silencers. This study sheds light on constant warfare between viruses and microbes, with economic impacts on industries using microbe cultures.
Delft University of Technology researchers have observed the spontaneous repair of DNA damage in real time, revealing a key mechanism for repairing breaks. This insight is crucial as errors in this process can lead to cancerous cell development.
Researchers found that HIV protease inhibitors can decrease photoreceptor apoptosis in mouse models of retinal detachment. The study suggests that these drugs may prevent vision loss after retinal detachment by inhibiting mitochondrial apoptosis.
A research study has found that a simple blood test can indicate whether post-menopausal hormone therapies increase the risk of a heart attack. Women with favorable cholesterol levels were not at increased risk of developing heart problems while taking hormones, whereas those with unfavorable cholesterol levels were at higher risk.
A 20-year study found that group-based diet and exercise lifestyle interventions reduced diabetes incidence by 51% during the intervention period and 43% over 20 years. The interventions also led to a significant reduction in the duration of diabetes, with participants spending an average of 3.6 fewer years with the condition.
A recent study published in the Journal of the Science of Food and Agriculture reveals that oregano oil is as effective as synthetic insecticides in controlling Rhizoppertha dominica beetle infestations. The natural compound works by inhibiting egg laying and larval development, posing no environmental harm.
The research center will focus on soft materials, building upon a solid foundation of liquid crystal research. The project aims to accelerate the development of new products at Ohio-based companies, supporting regional economic priorities.
The current figure of 246 million adults worldwide with diabetes is expected to expand rapidly, with 50% of deaths attributed to cardiovascular disease. The Lancet Editorial emphasizes that much of the morbidity and mortality can be prevented through targeted prevention strategies.
Research finds that gender stereotypes can limit both men and women's intentions to become entrepreneurs. However, when entrepreneurship is presented as a gender-neutral career option, both men and women report similar intentions.
Researchers discovered that HIV protease inhibitors can prevent photoreceptor apoptosis in mouse models of retinal detachment, reducing the cause of vision loss. CD133 expression was found not to be restricted to stem cells, and both CD133+ and CD133– metastatic colon cancer cells can initiate tumors.
An experimental drug, OSU-HDAC42, has blocked prostate cancer progression in mice with an aggressive form of the disease. The agent reactivates genes that normally protect against cancer, shifting tumor progression to a more benign direction.
The home telehealth and remote patient monitoring market is projected to grow at a rate of 70% over the next three to five years, driven by increasing demand for convenient and accessible healthcare services. The combined average annual revenue growth of consumer companies in this market is even more explosive, reaching up to 193.5%.
Researchers found that antidepressant use during the first trimester of pregnancy is not associated with an increased risk of birth malformations. The study used data from the Quebec Pregnancy Registry and analyzed records of 2,329 new mothers diagnosed with psychiatric disorders.
Researchers at Beth Israel Deaconess Medical Center have identified a 'food-related clock' that can supersede the body's primary biological rhythms, enabling better coping with changes in time zones and nighttime schedules. By adjusting eating schedules, humans may be able to adapt more quickly to new time zones.
Astronomers capture high-resolution images of Jupiter's turbulent atmosphere using NASA's Hubble Space Telescope and the W. M. Keck Observatory. The images reveal increased changes in the planet's atmosphere, including a color change from white to red near the Great Red Spot.
The Mars rover Spirit has discovered Yellowstone-like hot spring deposits on Mars, suggesting a habitable environment where liquid water and energy were present. The silica deposits, formed by volcanic steam or hot water, may contain preserved traces of ancient Martian life.
Researchers identified a gene that controls the proper development of synapses in fruit flies, which may help explain how they go wrong in humans. The findings suggest that a protein complex helps regulate synaptic growth by decommissioning receptors that respond to pro-growth signals.
Researchers have discovered high levels of acidified ocean water off the West Coast of North America, with corrosive levels detected within 20 miles of the shoreline. The acidic water is likely 50 years old and may increase in future due to rising atmospheric CO2 levels.
Two Rutgers College of Nursing doctoral students, Donna Ho-Shing and Stephanie Turrise, have been awarded FNSNA Fellowships to support their tuition and academic expenses during their online PhD program. The fellowship aims to address the nurse faculty shortage by preparing registered nurses for a career as nurse educators.
Type 1 diabetes incidence among Finnish children more than doubled from 1980-2005, with a significant increase in obesity and early weight gain implicated as risk factors. The predicted cumulative number of new cases between 2006-2020 is around 10800, highlighting the need for urgent action to address environmental triggers.
A recent study published in Aggressive Behavior found that high school girls who perceive themselves as attractive have a 35% increased chance of being indirectly victimized. Older teens who are sexually active also face a higher risk, with a 35% increased likelihood of being bullied.
Researchers identified gene mutations in FIGLA as a cause of premature ovarian failure, which can lead to infertility and other health issues. The study found three types of mutations in the gene, highlighting its importance in ovary function.
Researchers found a common core skin microbiome in healthy individuals, dominated by Proteobacteria species. The study establishes the basis for determining a core microbiome, which may hold the key to novel treatments for skin conditions like acne and atopic dermatitis.
A new statistical approach has been developed to study genetic variation, allowing for a finer detail of human migration history. The technique analyzes shared parts of chromosomes across the entire human genome, identifying smaller genetic contributions and surprising findings such as Mongolian ancestry in Native American Pima people.
A review of 21 studies found no systematic association between 100% fruit juice consumption and overweight in children or adolescents. Health professionals are encouraged to promote moderate consumption of 100% fruit juice as a strategy to help children meet fruit recommendations.
A study found that succinobucol reduced cardiovascular death, heart attack, and stroke in some patients, but also increased LDL cholesterol and atrial fibrillation. However, it improved glycated haemoglobin levels, suggesting potential benefits for long-term diabetes control.
A large US study found that sirolimus increases the risk of new-onset diabetes in kidney transplant recipients. The risk is higher when combined with other anti-rejection drugs and appears to be independent of other factors.
Researchers at OHSU have developed new antibodies that can recognize pancreatic cancer and gastrointestinal cancers. These antibodies show promise in early detection and treatment of pancreatic cancer, which is the fourth-leading cause of cancer death in the US.
A recent study reveals that 16 out of 21 oceanic shark and ray species are at risk of extinction due to unregulated and unsustainable fishing practices. Governments can take key steps to safeguard populations, including establishing science-based catch limits and ending shark finning.
Research shows tobacco promotions were extensive in Ontario stores, with chain convenience stores having large displays and signs advertising tobacco. The study found that tobacco promotions were higher among stores close to schools and in low-income neighbourhoods.
The Phoenix Mars Mission will investigate the Martian environment, searching for signs of climate cycles and microbial life. The spacecraft will collect soil and ice samples and analyze them to understand the Red Planet's history.
A randomized controlled trial found that early intensive insulin therapy improved blood glucose control and β-cell function in patients with newly diagnosed type 2 diabetes. The treatment, which included continuous subcutaneous insulin infusion or multiple daily insulin injections, resulted in higher remission rates and prolonged glyc...
Astronomers captured X-ray outburst from supernova SN 2008D, shedding light on early processes. The explosion was likely from a massive star with retained helium layer, providing valuable information for understanding stellar deaths.
Research highlights the critical role of food intolerance in IBS symptoms, particularly diarrhea, which alters epithelial function and increases intestinal permeability. The study provides valuable insights into the relationship between intestinal inflammation and increased permeability in IBS patients.
Advances in sequencing and surveillance have enabled researchers to identify circulating strains of HIV-1, with subtype B prevalent in the Americas and clades A, C, and D in Sub-Saharan Africa. The study highlights the importance of viral diversity on disease progression and transmission.
A study found that babies born by cesarean section showed a reduction in the suppressive function of their regulatory T-cells. This could be an important factor influencing immune system development in the neonate. Further research is needed to explore potential mechanisms.
Primary pancreatic MFH is a rare entity with distinct clinical characteristics, requiring prompt diagnosis for effective treatment. Characteristic imaging findings include large, liquescent-necrosis masses or multilocular cystic lesions with calcification on CT scans.
A plague of kangaroos is overgrazing Canberra's natural grasslands, leading to dramatic consequences for other species. The eastern grey kangaroo's population has multiplied so much that it now outnumbers the city's inhabitants, threatening the survival of rare species like the golden sun moth and grassland earless dragon.
Research on caribou in West Greenland reveals that climate change is affecting not only the timing of plant growth but also the availability of nutritious food. This 'trophic mismatch' leads to reduced births and increased deaths among caribou calves, highlighting the need for conservation efforts to protect seasonal animals.
A researcher at the University of Western Ontario is studying the relationship between global warming, nutrient enrichment, and lake systems to understand the complex dynamics of climate change. The study aims to identify how human activities impact regional temperature, hydroclimates, and aquatic ecosystems.
Tejate, a traditional Maize and Cacao Beverage from Oaxaca, Mexico, holds the key to understanding the future of agriculture and food variety. The authors found that tejate is in decline in modern communities but remains associated with traditional farmers' varieties, which are essential for preserving crop diversity.
A new method of chemosensitivity testing was found to provide predictive information that could lead to better treatment outcomes for gastric cancer patients. The study's results showed a longer overall 5-year survival time in the sensitive group compared to the control group.
Research findings suggest that high-volume surgeons at high-volume centers have improved in-hospital mortality rates for liver resections. Additionally, hospitals with a high annual volume of IBD patients experience lower mortality rates among hospitalized patients who undergo surgery.
Researchers developed a biomimetic jumping robot inspired by grasshoppers, capable of jumping 1.4 meters and navigating rough terrain with ease. The tiny robot can be fitted with sensors and solar cells to aid in search and rescue operations or explore remote areas on Earth or other planets.
A study by University of Leeds engineers found that roasting energy crops using the torrefaction process can increase their energy content, reducing transportation costs and emissions. Willow emerged as the most favourable crop, retaining 86% of its mass and performing best in terms of energy yield.
Astronomers have observed a rare 'normal' supernova for the first time at its moment of birth, thanks to NASA's Swift satellite. The discovery provides unique insights into how these massive star explosions occur, with the radiation pattern giving scientists the clearest picture ever.
Researchers at Argonne National Laboratory have developed a new method to predict the properties of light nuclei, allowing for better understanding of element origins and star behavior. This breakthrough enables more accurate calculations of nuclear reaction rates, which are crucial for astrophysics experiments.
A team of scientists from Johns Hopkins University used data from NASA's New Horizons spacecraft and multiple telescopes to observe the high winds in Jupiter's Little Red Spot. The winds have increased substantially over previous storms, with maximum speeds reaching 384 miles per hour, surpassing Category 5 storm thresholds.
Two studies using data from the CARDIA cohort provide insights into lung disease and lung function in young adults. Low levels of adiponectin in fat cells are associated with an increased risk of asthma in women, while high levels of ICAM-1 are linked to lower lung function.
Researchers found that alum stimulates clusters of proteins called inflammasomes, which respond to stresses such as infection or injury by releasing immune cell signaling proteins. This discovery provides evidence for the role of Nalp3 inflammasome in alum's adjuvant action.
A new analysis of nearly 7 million US live births found that babies born preterm were more than twice as likely to have major birth defects. The study also showed that very preterm babies, those born between 24-31 weeks gestation, were five times more likely to have a birth defect.
The HORIZONS AMI trial found bivalirudin significantly reduces major bleeding and cardiovascular events in STEMI patients undergoing angioplasty. The study showed a 24% reduction in net adverse clinical events and a 33% decrease in overall mortality at 30 days.
A nested case-control study found that high HBV DNA levels are associated with an increased risk of hepatocellular carcinoma. Patients with higher viral loads have a heightened potential for developing liver cancer, suggesting a potential correlation between viral load and liver cancer development.
Researchers will discuss climate models, air pollution, ozone levels, and their impact on regions like California, Texas, and the southeastern United States. Scientists also explore long-range transport of pollutants from Europe to Africa and the Near East.
Scientists have determined the structure of a catalytic material that can convert methane into benzene, laying the foundation for converting excess methane into various useful fuels and chemicals. The breakthrough was achieved using an ultra-high field nuclear magnetic resonance spectrometer to analyze the active catalyst.
Researchers found that serum RASSF1A promoter hypermethylation is a promising biomarker for diagnosing gastric and colorectal cancer. The study detected higher rates of this abnormality in tumor tissues and patient sera compared to benign disease or healthy individuals.