The new pilot program aims to recover organs from deceased individuals who die of cardiac arrest outside of hospitals, honoring their wishes and saving lives. The program has the potential to transform organ donation in the US, making it possible for more people to become donors regardless of where they die.
Research published in Frontline Gastroenterology finds that Crohn's disease patients are more likely to experience worsening symptoms if they have post-traumatic stress disorder (PTSD), with nearly one in five patients scoring high on the PTSD scale
Researchers from 38 institutions collaborate to study neutrinos in the Daya Bay project. The team aims to understand how neutrinos transition between types and shed light on the universe's matter-antimatter imbalance.
Researchers have described the first functioning 'lipidome' of a mouse macrophage, a white blood cell, providing new insights into how lipids interact and change over time in response to bacterial stimuli. The study sheds light on the crucial role of lipid molecules in inflammation and disease.
A new study suggests preterm infants are at risk of invasive pneumococcal disease despite receiving the pneumococcal conjugate vaccine. Early effective immunization is crucial, as they have lower levels of maternally derived antibody than full-term infants.
A study of 614 vineyard workers in South West France found a link between long-term pesticide exposure and declining cognitive abilities, including lower scores on memory and recall tests. The researchers suggest that higher risks of dementia may be associated with pesticide exposure.
Research shows that damage to nerve supply controlling eye movement is a common problem after stroke, impacting reading abilities and rehabilitation. Stricter assessment methods are necessary to detect vision problems as stroke after-effects rather than age-related symptoms.
Researchers discovered a protein necessary for normal cell division in blood-forming stem cells, which resulted in abnormal numbers of chromosomes and high rates of cell death. This finding highlights the metabolic differences between stem cells and other blood-forming cells.
Researchers at Case Western Reserve University have developed a novel capacitor design that could significantly increase energy density in power supplies for electric cars. The new technology uses titanium alloy and advanced materials to create a highly efficient and compact device capable of absorbing and providing surges of electricity.
A study of 88 Parkinson's outpatients found that 72% experienced fatigue or excessive daytime sleepiness, with 60% of fatigued patients also experiencing EDS. Fatigue was more common in those without EDS, while EDS worsened with dopamine agonist treatment.
Researchers from Boston University School of Medicine have identified a mechanism by which specific viruses acting as oncolytic agents can enter and kill cancer cells. By targeting the AKT signaling pathway, VSV is able to switch off a major cell survival signal, leaving cancer cells vulnerable to attack.
Astronomers at Yale University have discovered that small red dwarfs are much more prolific than previously believed, increasing the total number of stars in the universe. The discovery found 20 times more red dwarfs in elliptical galaxies than in the Milky Way, with potential implications for galaxy formation and evolution.
Global coastal wetlands are likely to disappear near the end of the 21st century, with limited sediment supplies and tidal ranges making them vulnerable. Wetlands with higher sediment availability may survive under slow sea-level rise projections.
A new study by UC Davis researchers found that Southeast-Asian-American families with children having developmental disabilities face significant obstacles in receiving intervention services. Barriers include limited information, language difficulties and a perception that reliance on government support is not acceptable.
Researchers at The Children's Hospital of Philadelphia have discovered a new gene, LMO1, as a significant contributor to neuroblastoma, the most common solid cancer of early childhood. Variants in this gene increase the risk of developing aggressive forms of neuroblastoma and mark the gene for continued disease progression.
A new set of multi-lingual tools has been released by Science-Metrix Inc. to visualize the links between scientific specialties in 18 languages. The tools include a classification of 15,000 peer-reviewed scientific journals, allowing users to track performance and research dynamics.
A large-scale study found that military deployment significantly influences sleep quality and quantity, with participants reporting 28% more trouble falling asleep during deployment. The study suggests promoting healthier sleep patterns may be beneficial for military service members, particularly those with mental health issues.
A study found that loud snoring and difficulty falling asleep predict the development of metabolic syndrome, a key risk factor for cardiovascular disease. The risk was significantly higher in adults who reported frequent loud snoring or unrefreshing sleep.
Researchers found a duplicated region of DNA on chromosome 5 predisposes people to major depression, implicating disruptions in neurotransmission networks. The study identified 12 copy number variations exclusive to MDD cases, with a large duplication of the SLIT3 gene contributing to the risk.
New analysis suggests that stenting can perform as well as surgery for treating narrowed carotid vessels, with age being a significant factor. For younger patients (under 70) with symptoms related to the condition, stenting proved effective in reducing stroke risk.
A study published in Nature found that species loss leads to increases in disease-causing organisms, increasing the risk of infectious diseases such as Lyme disease and hantavirus. The researchers argue that preserving natural habitats is crucial to preventing this effect.
The southeastern United States is home to a diverse array of fish species, but poor stream health poses a significant threat to their survival. The region's growing population and increasing demands on water resources have led to widespread degradation of aquatic habitats.
A new explanation of how humans solve problems creatively has been introduced, providing a roadmap for building systems that perform like humans. The theory proposes the coexistence of two types of knowledge and processing: explicit and implicit. By incorporating this principle, computers can now mimic human creativity in problem-solving.
Researchers developed a shoe-embedded radar system to aid pedestrian navigation, reducing errors in GPS-less situations. The technology uses inertial measurement units (IMUs) with an independent radar sensor to track movement and position.
Researchers identified a crucial protein, LXR-beta, involved in the negative side effects of glucocorticoid drugs. Targeting this protein may lead to safer drug designs. Additionally, TXNL2 is found to protect human breast cancer cells from oxidative stress, while mutations in SLC1A1 cause rare kidney disorder dicarboxylic aminoaciduria.
Tel Aviv University researchers discovered that endurance exercises increase muscle stem cells and enhance their ability to rejuvenate old muscles. This finding could lead to a new drug to help the elderly and immobilized heal their muscles faster.
Men with longer index fingers are at a lower risk of developing prostate cancer, while those with shorter index fingers are more likely to be diagnosed. The study found that men aged under 60 were 87% less likely to have prostate cancer if their index finger was longer than their ring finger.
Joslin researchers found that brain cholesterol synthesis decreases in mouse models of diabetes, affecting nerve function and potentially leading to increased appetite and weight gain. The study suggests a link between diabetes and altered brain function, including changes in Alzheimer's disease risk and diabetic neuropathy.
A USGS study reveals that growing corn for biofuels production has significant effects on water quality and quantity in northwestern Mississippi. Increased irrigation withdrawals from the MRVA aquifer contribute to declining water levels, while nitrogen fertilizer use can lead to low dissolved oxygen conditions in the Gulf of Mexico.
The Hastings Center has issued recommendations on growth attenuation, a controversial procedure used to restrict the growth of profoundly disabled children. The guidelines prioritize parental autonomy while establishing safeguards to ensure the child's well-being.
A new study reveals how diabetes disrupts brain cholesterol synthesis, leading to neurologic complications such as depression and increased Alzheimer's disease risk. Insulin therapy restores normal cholesterol production in the brain.
Advanced riders with formal training demonstrated better road positioning, hazard perception, and progress through bends compared to novice and experienced riders without training. The study suggests that formal advanced training can improve safety on the roads.
The Megaframe Imager, a new ultrafast camera, uses an extremely sensitive SPAD device to detect viral DNA binding events at low target concentrations. This technology has potential applications in biological processes, automotive collisions, and astronomical observations.
The US Department of Energy is awarding time on two world-leading supercomputers to 57 innovative research projects. These projects aim to advance scientific discoveries in areas such as renewable energy solutions, understanding environmental impacts, and developing new technologies like rechargeable batteries and hydrogen fuel. The pr...
A study published in Cell Metabolism found that a protein called Angiopoietin-like protein 4 (Angptl4) protects against the severe inflammatory response caused by high levels of saturated fat. Mice deficient in this protein showed massive lymph node expansion and died after consuming a diet high in saturated fats.
A study reviews nuclear power economics and concludes that the current fuel cycle is unsustainable due to uncertainty about waste management. Reprocessing and recycling of spent fuel is an alternative, but its implementation is controversial due to proliferation risks and high costs.
Researchers used a new brain imaging technique to test an investigational drug for Parkinson's disease, finding it may be effective when combined with levodopa. The study suggests the method could speed drug development and improve treatment outcomes.
A new report commissioned by The National Academy on an Aging Society finds that older adults with diabetes have a lower life expectancy than those without the disease. The analysis, based on data from the Health and Retirement Study, reveals a significant increase in diabetes prevalence among boomers and seniors.
A study of 200 top-selling children's liquid medications found high variability in labeling and measuring devices, with nearly all products containing at least one inconsistency. The researchers highlight three critical areas for improvement: standardized measuring devices, consistent dosing directions, and standardized measurement units.
Scientists discovered a mysterious high-altitude sulphur dioxide layer on Venus that can help explain its formation. The new findings also suggest that injecting large quantities of sulphur dioxide into Earth's atmosphere to mitigate climate change may not be as effective as thought.
Research shows anti-microbial medications are a leading cause of drug-induced liver injury, with women and minorities disproportionately affected. Liver transplantation offers excellent survival rates, but further investigation is needed to understand the impact of alcohol use and diabetes.
A study published in Clinical Gastroenterology and Hepatology found that IBD patients with hospital-acquired infections experience increased mortality and prolonged hospital stays. The majority of infections among hospitalized IBD patients are health-care associated, with severe liver disease patients being at highest risk.
A Columbia University engineering team has discovered how pure graphene breaks under tensile stress, revealing a novel soft-mode phonon instability that leads to mechanical failure. This finding is significant for understanding the behavior of low-dimensional systems like graphene and could lead to new ways to engineer its properties.
A two-part treatment using injections of a patient's own blood and steroid, combined with dry-needling, has shown significant improvements in functionality and pain reduction for patients with hamstring tendinopathy. The study found that this treatment approach outperformed traditional steroid therapy alone.
Researchers at UC Davis Health System found significantly reduced vitamin D levels in patients with metabolic syndrome living in Northern California. The study suggests that supplementation with vitamin D may reduce the risk of diabetes and heart disease, contradicting previous assumptions about adequate sun exposure in sunny latitudes.
A team of astronomers used the Moon to search for ultra-high-energy neutrinos from distant regions of space. They reported their findings in the December edition of the journal Astroparticle Physics, setting a new upper limit on the amount of such particles arriving from space.
Research by University of Minnesota psychologists shows that invisible emotional and practical support from partners significantly reduces anger, anxiety, and increases self-efficacy. The study provides new insights into the dynamics of social support in couples.
Active surveillance outperforms initial treatment for low-risk prostate cancer, providing a higher quality-adjusted life expectancy (QALE) and reducing adverse effects of treatment. The optimal strategy depends on individual patient preferences for surveillance or treatment.
A new study by Binghamton University researchers suggests that individual differences in sexual behavior could be influenced by genetic variation, particularly the dopamine receptor D4 polymorphism. This gene is linked to sensation-seeking behavior, such as alcohol use and gambling, and may contribute to promiscuity and infidelity.
Exposure to arsenic in rural Bangladesh is poisonous to the nation's economy, reducing labor supply by 8 percent. The study also shows that women are working fewer hours outside the home while men are working more to compensate for the lack of healthcare access.
A recent study from Université de Montréal found that using alternative therapies for asthma can result in a two-fold higher rate of poor asthma control in children. The study assessed over 2000 families with children and found that use of alternative therapy was associated with reduced effectiveness of conventional asthma treatment.
A cluster of articles in PLoS Medicine highlights the need to improve global health estimation and data measurement. Experts argue that the process has become overly politicized and that action is needed to address the most vulnerable populations' health needs.
A new study reconstructs America's colonial hydrology, revealing the integral role of water resources in shaping human settlement patterns. By integrating modern scientific data with historical records, researchers have gained insights into the evolution of watersheds and ecosystems.
Researchers found reduced enzyme activity in young adult brains carrying the APOE4 gene, a common Alzheimer's risk factor. The study suggests mitochondrial changes contribute to disease risk, providing a potential target for prevention therapies.
Researchers at Rensselaer Polytechnic Institute developed a technique to probe the temperature rise in the vicinity of RF-actuated nanoparticles. The study found that the measured temperature rise was consistent regardless of whether the sensors were mixed with or covalently bonded to the nanoparticles.
Researchers discovered that exposure to high levels of air pollution narrows tiny blood vessels in the retina, increasing the risk of heart disease. Exposure to even small amounts of pollution can cause a 3% increase in heart disease risk for women living in polluted areas.
Boa constrictors use a unique concertina mode of locomotion to grip and climb ropes of different diameters, adapting their movement based on environmental conditions. The study provides insight into the animals' musculoskeletal design and its relation to their natural habitat.
Researchers found that law firms led by managing partners with powerful faces in college were more profitable, and that facial cues can predict success across a lifespan of approximately 20 years. The study used ratings from judges to measure perceived power and correlated them with firm profits.
A new study by Milton Diamond and colleagues found that legalizing child pornography in the Czech Republic led to a significant decrease in reported cases of child sex abuse. The study's findings also suggest that potential sexual offenders use child pornography as a substitute for sex crimes against children.
A University of Pittsburgh study will test a technology-enhanced weight loss program using text messaging reminders and wearable exercise monitors. The study aims to compare the effectiveness of this intervention with a standard behavioral weight loss program.