Researchers used gene therapy to deliver a portion of DNA that makes the SMN protein into newborn mice, resulting in improved muscle coordination and longer survival. The treatment corrected motor function, restored nerve signals, and improved overall health in mice with spinal muscular atrophy.
A systematic review found inadequate coverage of effective interventions for HIV prevention among injecting drug users globally. Only 8% of injectors have accessed needle and syringe programs in the last year, with coverage varying greatly between countries.
Researchers at Johns Hopkins Children's Center report encouraging results in children with egg allergies who consume increasingly higher doses of egg protein. The study found that more than half of the children could tolerate 5 grams of eggs without an allergic reaction, experiencing mild to moderate symptoms.
Researchers at the Salk Institute discover two genetic master switches that determine a plant's polar axis, with one group promoting root development and the other shoot growth. The study reveals an antagonistic relationship between these switches, which are regulated by multiple mechanisms to ensure proper spatial distribution.
A new investigational drug, bapineuzumab, has been shown to reduce amyloid-β deposits in the brain by 25% in patients with mild-to-moderate Alzheimer's disease. This breakthrough finding could help assess the efficacy of other drugs for Alzheimer's treatment.
Beewolves have evolved a symbiotic relationship with bacteria of the genus Streptomyces that produce nine different antibiotics, providing effective protection against various pathogens. This natural defense mechanism, known as combination prophylaxis, has been used by beewolves for millions of years to safeguard their offspring.
A new technique called Fast Relaxation Imaging enables real-time observation of protein folding and unfolding in living cells. The method reveals that proteins are more stable and their thermal denaturation is more gradual in a cellular environment compared to an in vitro setting.
A new study has identified four key aspects of immune system disturbance that contribute to the development of coeliac disease, including how T cells react to toxic wheat proteins and the body's response to viral infections. The research also suggests a shared risk between coeliac disease and other chronic immune-mediated diseases.
Researchers discovered that caddisfly larvae's underwater silk adhesive is sticky and has potential to be used as a medical bioadhesive in surgery. The silk, known as 'rock rollers,' may be useful for sticking wet tissues together, similar to using a wet Band-Aid.